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Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells
Nature
Abraham, SA;Hopcroft, LE;Carrick, E;Drotar, ME;Dunn, K;Williamson, AJ;Korfi, K;Baquero, P;Park, LE;Scott, MT;Pellicano, F;Pierce, A;Copland, M;Nourse, C;Grimmond, SM;Vetrie, D;Whetton, AD;Holyoake, TL;
2016
27281222
June 8th, 2016
United Kingdom
Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Gartnavel General Hospital, 1053 Great Western Road, Glasgow G12 0YN, UK
Dysfunction of parvalbumin neurons in the cerebellar nuclei produces an action tremor
J. Clin. Invest.
Zhou, M;Melin, MD;Xu, W;Sudhof, TC;
2020
32634124
July 7th, 2020
United States
Department of Molecular and Cellular Physiology, Stanford University, Stanford, United States of America
Ischemic Preconditioning Protects Astrocytes against Oxygen Glucose Deprivation Via the Nuclear Erythroid 2-Related Factor 2 Pathway
Translational Stroke Research
Narayanan, SV;Dave, KR;Perez-Pinzon, MA;
2017
29103101
November 4th, 2017
United States
Cerebral Vascular Disease Research Laboratories, School of Medicine, University of Miami Miller, Miami, FL, USA
Biomechanical forces promote embryonic haematopoiesis
Nature
Adamo, L;Naveiras, O;Wenzel, PL;McKinney-Freeman, S;Mack, PJ;Gracia-Sancho, J;Suchy-Dicey, A;Yoshimoto, M;Lensch, MW;Yoder, MC;GarcÌ_a-Carde̱a, G;Daley, GQ;
2009
19440194
June 25th, 2009
United States
Center for Excellence in Vascular Biology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
RAS and RHO families of GTPases directly regulate distinct phosphoinositide 3-kinase isoforms
Cell
Fritsch, R;de Krijger, I;Fritsch, K;George, R;Reason, B;Kumar, MS;Diefenbacher, M;Stamp, G;Downward, J;
2013
23706742
May 23rd, 2013
United Kingdom
Signal Transduction Laboratory, Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3LY, UK
Hunger states switch a flip-flop memory circuit via a synaptic AMPK-dependent positive feedback loop
Cell
Yang, Y;Atasoy, D;Su, HH;Sternson, SM;
2011
21925320
September 16th, 2011
United States
Janelia Farm Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA
Genetic tracing via DNGR-1 expression history defines dendritic cells as a hematopoietic lineage
Cell
Schraml, BU;van Blijswijk, J;Zelenay, S;Whitney, PG;Filby, A;Acton, SE;Rogers, NC;Moncaut, N;Carvajal, JJ;Reis e Sousa, C;
2013
23953115
August 15th, 2013
United States
Immunobiology Laboratory, Cancer Research UK, London Research Institute, Lincoln's Inn Fields Laboratories, 44 Lincoln's Inn Fields, London WC2A 3LY, UK
The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-ë_ locus
Cell
Gomez, JA;Wapinski, OL;Yang, YW;Bureau, JF;Gopinath, S;Monack, DM;Chang, HY;Brahic, M;Kirkegaard, K;
2013
23415224
February 14th, 2013
United States
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
The retinoblastoma binding protein RBP2 is an H3K4 demethylase
Cell
Klose, RJ;Yan, Q;Tothova, Z;Yamane, K;Erdjument-Bromage, H;Tempst, P;Gilliland, DG;Zhang, Y;Kaelin, WG;
2007
17320163
March 9th, 2007
United States
Howard Hughes Medical Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Hijacking the neuronal NMDAR signaling circuit to promote tumor growth and invasion
Cell
Li, L;Hanahan, D;
2013
23540692
March 28th, 2013
Switzerland
Swiss Institute for Experimental Cancer Research, School of Life Science, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne 1015, Switzerland
Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML
Cell
Puram, RV;Kowalczyk, MS;de Boer, CG;Schneider, RK;Miller, PG;McConkey, M;Tothova, Z;Tejero, H;Heckl, D;JÌ_rÌ´s, M;Chen, MC;Li, H;Tamayo, A;Cowley, GS;Rozenblatt-Rosen, O;Al-Shahrour, F;Regev, A;Ebert, BL;
2016
27058663
April 1st, 2016
United States
Department of Medicine, Division of Hematology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of Harvard University and MIT, Cambridge, MA 02142, USA; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA
53BP1 regulates DSB repair using Rif1 to control 5'' end resection
Science
Zimmermann, M;Lottersberger, F;Buonomo, SB;Sfeir, A;de Lange, T;
2013
23306437
February 1st, 2013
United States
Laboratory for Cell Biology and Genetics, Rockefeller University, New York, NY 10065, USA
Thalamic miR-338-3p mediates auditory thalamocortical disruption and its late onset in models of 22q11.2 microdeletion
Nature Medicine
Chun, S;Du, F;Westmoreland, JJ;Han, SB;Wang, YD;Eddins, D;Bayazitov, IT;Devaraju, P;Yu, J;Mellado Lagarde, MM;Anderson, K;Zakharenko, SS;
2016
27892953
November 28th, 2016
United States
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses
Nature Medicine
Moynihan, KD;Opel, CF;Szeto, GL;Tzeng, A;Zhu, EF;Engreitz, JM;Williams, RT;Rakhra, K;Zhang, MH;Rothschilds, AM;Kumari, S;Kelly, RL;Kwan, BH;Abraham, W;Hu, K;Mehta, NK;Kauke, MJ;Suh, H;Cochran, JR;Lauffenburger, DA;Wittrup, KD;Irvine, DJ;
2016
27775706
December 1st, 2016
United States
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA
Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma
Nature Medicine
Ambrogio, C;GÃŒ_mez-LÃŒ_pez, G;Falcone, M;Vidal, A;Nadal, E;Crosetto, N;Blasco, RB;FernÃŒÃndez-Marcos, PJ;SÃŒÃnchez-CÌ©spedes, M;Ren, X;Wang, Z;Ding, K;Hidalgo, M;Serrano, M;Villanueva, A;SantamarÃŒ_a, D;Barbacid, M;
2016
26855149
March 1st, 2016
Spain
Experimental Oncology, Molecular Oncology Programme, Centro Nacional de Investigaciones OncolÌ_gicas (CNIO), Madrid, Spain
Loss of BAP1 function leads to EZH2-dependent transformation
Nature Medicine
LaFave, LM;BÌ©guelin, W;Koche, R;Teater, M;Spitzer, B;Chramiec, A;Papalexi, E;Keller, MD;Hricik, T;Konstantinoff, K;Micol, JB;Durham, B;Knutson, SK;Campbell, JE;Blum, G;Shi, X;Doud, EH;Krivtsov, AV;Chung, YR;Khodos, I;de Stanchina, E;Ouerfelli, O;Adusumilli, PS;Thomas, PM;Kelleher, NL;Luo, M;Keilhack, H;Abdel-Wahab, O;Melnick, A;Armstrong, SA;Levine, RL;
2015
26437366
November 1st, 2015
United States
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Epidermal growth factor regulates hematopoietic regeneration after radiation injury
Nature Medicine
Doan, PL;Himburg, HA;Helms, K;Russell, JL;Fixsen, E;Quarmyne, M;Harris, JR;Deoliviera, D;Sullivan, JM;Chao, NJ;Kirsch, DG;Chute, JP;
2013
23377280
March 1st, 2013
United States
Department of Medicine, Division of Hematologic Malignancies and Cellular Therapy, Durham, North Carolina, USA
DNA sequencing: generation next-next
Nature Methods
Blow, N;
2008
March 15th, 2008
United States
The Editor of Nature Methods, One New York Plaza, Suite 4500,New York, NY 10004-1562, USA
IL-37 requires the receptors IL-18Rë± and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
Nature Immunology
Nold-Petry, CA;Lo, CY;Rudloff, I;Elgass, KD;Li, S;Gantier, MP;Lotz-Havla, AS;Gersting, SW;Cho, SX;Lao, JC;Ellisdon, AM;Rotter, B;Azam, T;Mangan, NE;Rossello, FJ;Whisstock, JC;Bufler, P;Garlanda, C;Mantovani, A;Dinarello, CA;Nold, MF;
2015
25729923
April 1st, 2015
Australia
1] Ritchie Centre, MIMR-PHI Institute of Medical Research, Melbourne, Victoria, Australia. [2] Department of Paediatrics, Monash University, Melbourne, Australia
The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses
Nature Immunology
Khare, S;Ratsimandresy, RA;de Almeida, L;Cuda, CM;Rellick, SL;Misharin, AV;Wallin, MC;Gangopadhyay, A;Forte, E;Gottwein, E;Perlman, H;Reed, JC;Greaves, DR;Dorfleutner, A;Stehlik, C;
2014
24531343
April 1st, 2014
United States
Division of Rheumatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma
Cancer Cell
Blasco, RB;Francoz, S;SantamarÌ_a, D;Ca̱amero, M;Dubus, P;Charron, J;Baccarini, M;Barbacid, M;
2011
21514245
May 17th, 2011
Spain
Molecular Oncology, Centro Nacional de Investigaciones OncolÌ_gicas (CNIO), E-28029 Madrid, Spain
The ALK(F1174L) mutation potentiates the oncogenic activity of MYCN in neuroblastoma
Cancer Cell
Berry, T;Luther, W;Bhatnagar, N;Jamin, Y;Poon, E;Sanda, T;Pei, D;Sharma, B;Vetharoy, WR;Hallsworth, A;Ahmad, Z;Barker, K;Moreau, L;Webber, H;Wang, W;Liu, Q;Perez-Atayde, A;Rodig, S;Cheung, NK;Raynaud, F;Hallberg, B;Robinson, SP;Gray, NS;Pearson, AD;Eccles, SA;Chesler, L;George, RE;
2012
22789543
July 10th, 2012
United Kingdom
Division of Clinical Studies, The Institute of Cancer Research, Sutton, Surrey SM2 5NG, UK
Calcification of multipotent prostate tumor endothelium
Cancer Cell
Dudley, AC;Khan, ZA;Shih, SC;Kang, SY;Zwaans, BM;Bischoff, J;Klagsbrun, M;
2008
18772110
September 1st, 2008
United States
Vascular Biology Program, Children's Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling
Nature Cell Biology
Sandilands, E;Serrels, B;McEwan, DG;Morton, JP;Macagno, JP;McLeod, K;Stevens, C;Brunton, VG;Langdon, WY;Vidal, M;Sansom, OJ;Dikic, I;Wilkinson, S;Frame, MC;
2011
22138575
December 4th, 2011
United Kingdom
Edinburgh Cancer Research UK Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XR, UK
Suppression of microRNA activity amplifies IFN-ë_-induced macrophage activation and promotes anti-tumour immunity
Nature Cell Biology
Baer, C;Squadrito, ML;Laoui, D;Thompson, D;Hansen, SK;Kiialainen, A;Hoves, S;Ries, CH;Ooi, CH;De Palma, M;
2016
27295554
July 1st, 2016
Switzerland
Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ìäcole Polytechnique FÌ©dÌ©rale de Lausanne (EPFL), 1015åÊLausanne, Switzerland
PET imaging of leptin biodistribution and metabolism in rodents and primates
Cell Metabolism
Ceccarini, G;Flavell, RR;Butelman, ER;Synan, M;Willnow, TE;Bar-Dagan, M;Goldsmith, SJ;Kreek, MJ;Kothari, P;Vallabhajosula, S;Muir, TW;Friedman, JM;
2009
19656493
August 1st, 2009
United States
Laboratory of Molecular Genetics, Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA
Imaging activity in neurons and glia with a Polr2a-based and cre-dependent GCaMP5G-IRES-tdTomato reporter mouse
Neuron
Gee, JM;Smith, NA;Fernandez, FR;Economo, MN;Brunert, D;Rothermel, M;Morris, SC;Talbot, A;Palumbos, S;Ichida, JM;Shepherd, JD;West, PJ;Wachowiak, M;Capecchi, MR;Wilcox, KS;White, JA;Tvrdik, P;
2014
25155958
September 1st, 2014
United States
Department of Bioengineering, University of Utah, Salt Lake City, UT 84112; Brain Institute, University of Utah, Salt Lake City, UT 84112
Sexual divergence in microtubule function: the novel intranasal microtubule targeting SKIP normalizes axonal transport and enhances memory
Molecular Psychiatry
Amram, N;Hacohen-Kleiman, G;Sragovich, S;Malishkevich, A;Katz, J;Touloumi, O;Lagoudaki, R;Grigoriadis, NC;Giladi, E;Yeheskel, A;Pasmanik-Chor, M;Jouroukhin, Y;Gozes, I;
2016
26782054
October 1st, 2016
Israel
Lily and Avraham Gildor Chair for the Investigation of Growth Factors; Elton Laboratory for Neuroendocrinology; Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Sagol School of Neuroscience and Adams Super Center for Brain Studies, Tel Aviv University, Tel Aviv, Israel
Identification of neurodegenerative factors using translatome-regulatory network analysis
Nature Neuroscience
Brichta, L;Shin, W;Jackson-Lewis, V;Blesa, J;Yap, EL;Walker, Z;Zhang, J;Roussarie, JP;Alvarez, MJ;Califano, A;Przedborski, S;Greengard, P;
2015
26214373
September 1st, 2015
United States
Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York, USA
Diminished KCC2 confounds synapse specificity of LTP during senescence
Nature Neuroscience
Ferando, I;Faas, GC;Mody, I;
2016
27500406
September 1st, 2016
United States
Department of Neurology, The David Geffen School of Medicine, University of California, Los Angeles, California, USA
AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training
Nature Neuroscience
Aponte, Y;Atasoy, D;Sternson, SM;
2011
21209617
March 1st, 2011
United States
Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, Virginia, USA
Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in CCR2-/- mice: evidence for independent chemokine functions in atherogenesis
Circulation
Saederup, N;Chan, L;Lira, SA;Charo, IF;
2008
18165355
April 1st, 2008
United States
Gladstone Institute of Cardiovascular Disease, 1650 Owens St, San Francisco, CA 94158, USA
TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres
Molecular Cell
Kibe, T;Zimmermann, M;de Lange, T;
2016
26778124
January 21st, 2016
United States
Laboratory for Cell Biology and Genetics, Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
Inhibition of Tumor Growth and Metastasis in Pancreatic Cancer Models by Interference With CD44v6 Signaling
Gastroenterology
Matzke-Ogi, A;Jannasch, K;Shatirishvili, M;Fuchs, B;Chiblak, S;Morton, J;Tawk, B;Lindner, T;Sansom, O;Alves, F;Warth, A;Schwager, C;Mier, W;Kleeff, J;Ponta, H;Abdollahi, A;Orian-Rousseau, V;
2016
26597578
February 1st, 2016
United States
Karlsruhe Institute of Technology, Institute of Toxicology and Genetics, Eggenstein-Leopoldshafen, Germany
Ca2+ responses in enteric glia are mediated by connexin-43 hemichannels and modulate colonic transit in mice
Gastroenterology
McClain, JL;GrubiÂÃiۈ , V;Fried, D;Gomez-Suarez, RA;Leinninger, GM;SÌ©vigny, J;Parpura, V;Gulbransen, BD;
2014
24211490
February 1st, 2014
United States
Neuroscience Program and Department of Physiology, Michigan State University, East Lansing, Michigan
NOS1-derived nitric oxide promotes NF-ë¼B transcriptional activity through inhibition of suppressor of cytokine signaling-1
Journal of Experimental Medicine
Baig, MS;Zaichick, SV;Mao, M;de Abreu, AL;Bakhshi, FR;Hart, PC;Saqib, U;Deng, J;Chatterjee, S;Block, ML;Vogel, SM;Malik, AB;Consolaro, ME;Christman, JW;Minshall, RD;Gantner, BN;Bonini, MG;
2015
26324446
September 21st, 2015
United States
Department of Medicine, Department of Pharmacology, Department of Anesthesiology, and Department of Pathology, University of Illinois College of Medicine, Chicago, IL 60607 bgantner@uic.edu
Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression
Journal of Clinical Investigation
Patel, R;Gao, M;Ahmad, I;Fleming, J;Singh, LB;Rai, TS;McKie, AB;Seywright, M;Barnetson, RJ;Edwards, J;Sansom, OJ;Leung, HY;
2013
23434594
March 1st, 2013
United Kingdom
The Beatson Institute for Cancer Research, Glasgow, United Kingdom
Foxc1 and Foxc2 deletion causes abnormal lymphangiogenesis and correlates with ERK hyperactivation
Journal of Clinical Investigation
Fatima, A;Wang, Y;Uchida, Y;Norden, P;Liu, T;Culver, A;Dietz, WH;Culver, F;Millay, M;Mukouyama, YS;Kume, T;
2016
27214551
July 1st, 2016
United States
Feinberg Cardiovascular Research Institute, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth
Journal of Clinical Investigation
Jaba, IM;Zhuang, ZW;Li, N;Jiang, Y;Martin, KA;Sinusas, AJ;Papademetris, X;Simons, M;Sessa, WC;Young, LH;Tirziu, D;
2013
23454748
April 1st, 2013
United States
Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut 06510, USA
Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis
Journal of Clinical Investigation
Burstyn-Cohen, T;Heeb, MJ;Lemke, G;
2009
19729839
October 1st, 2009
United States
Molecular Neurobiology Laboratory, The Salk Institute, La Jolla, California, USA
Neurovascular crosstalk between interneurons and capillaries is required for vision
Journal of Clinical Investigation
Usui, Y;Westenskow, PD;Kurihara, T;Aguilar, E;Sakimoto, S;Paris, LP;Wittgrove, C;Feitelberg, D;Friedlander, MS;Moreno, SK;Dorrell, MI;Friedlander, M;
2015
25915585
June 1st, 2015
United States
Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, California, USA
Targeting mTOR dependency in pancreatic cancer
Gut
Morran, DC;Wu, J;Jamieson, NB;Mrowinska, A;Kalna, G;Karim, SA;Au, AY;Scarlett, CJ;Chang, DK;Pajak, MZ;, ;Oien, KA;McKay, CJ;Carter, CR;Gillen, G;Champion, S;Pimlott, SL;Anderson, KI;Evans, TR;Grimmond, SM;Biankin, AV;Sansom, OJ;Morton, JP;
2014
24717934
September 1st, 2014
United Kingdom
CRUK Beatson Institute, Glasgow, UK
Ketone bodies mediate antiseizure effects through mitochondrial permeability transition
Annals of Neurology
Kim, DY;Simeone, KA;Simeone, TA;Pandya, JD;Wilke, JC;Ahn, Y;Geddes, JW;Sullivan, PG;Rho, JM;
2015
25899847
July 1st, 2015
United States
Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, AZ
Matrix metalloproteinase 3 deletion preserves denervated motor endplates after traumatic nerve injury
Annals of Neurology
Chao, T;Frump, D;Lin, M;Caiozzo, VJ;Mozaffar, T;Steward, O;Gupta, R;
2013
23281061
February 1st, 2013
United States
Department of Orthopaedic Surgery, University of California, Irvine, Irvine, CA, USA
Periostin is required for maximal airways inflammation andåÊhyperresponsiveness in mice
Journal of Allergy and Clinical Immunology
Bentley, JK;Chen, Q;Hong, JY;Popova, AP;Lei, J;Moore, BB;Hershenson, MB;
2014
24996263
December 1st, 2014
United States
Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Mich; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Mich
Endothelial cell-dependent regulation of arteriogenesis
Circulation Research
Moraes, F;Paye, J;Mac Gabhann, F;Zhuang, ZW;Zhang, J;Lanahan, AA;Simons, M;
2013
23897694
October 12th, 2013
United States
From the Department of Internal Medicine, Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, New Haven, CT
Biallelic Mutations in PDE10A Lead to Loss of Striatal PDE10A and a Hyperkinetic Movement Disorder with Onset in Infancy
American Journal of Human Genetics
Diggle, CP;Sukoff Rizzo, SJ;Popiolek, M;Hinttala, R;SchÌ_lke, JP;Kurian, MA;Carr, IM;Markham, AF;Bonthron, DT;Watson, C;Sharif, SM;Reinhart, V;James, LC;Vanase-Frawley, MA;Charych, E;Allen, M;Harms, J;Schmidt, CJ;Ng, J;Pysden, K;Strick, C;Vieira, P;Mankinen, K;Kokkonen, H;Kallioinen, M;Sormunen, R;Rinne, JO;Johansson, J;Alakurtti, K;Huilaja, L;Hurskainen, T;Tasanen, K;Anttila, E;Marques, TR;Howes, O;Politis, M;Fahiminiya, S;Nguyen, KQ;Majewski, J;Uusimaa, J;Sheridan, E;Brandon, NJ;
2016
27058446
April 7th, 2016
Finland
PEDEGO Research Unit and Medical Research Center Oulu, University of Oulu and Oulu University Hospital, PO Box 5000, 90014 Oulu, Finland; Department of Children and Adolescents, Oulu University Hospital, PO Box 23, 90029 Oulu, Finland; Biocenter Oulu, University of Oulu, PO Box 5000, 90014 Oulu, Finland
Transduction of group I mGluR-mediated synaptic plasticity by ë_-arrestin2 signalling
Nature Communications
Eng, AG;Kelver, DA;Hedrick, TP;Swanson, GT;
2016
27886171
November 25th, 2016
United States
Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa
Nature Communications
Chung, JJ;Navarro, B;Krapivinsky, G;Krapivinsky, L;Clapham, DE;
2011
21224844
January 11th, 2011
United States
1] Howard Hughes Medical Institute, Manton Center for Orphan Disease, Children's Hospital, Boston, Massachusetts 02115, USA.. [2] Department of Neurobiology, Harvard Medical School, Enders 1309, 320 Longwood Avenue, Boston, Massachusetts 02115, USA
P-Rex1 is required for efficient melanoblast migration and melanoma metastasis
Nature Communications
Lindsay, CR;Lawn, S;Campbell, AD;Faller, WJ;Rambow, F;Mort, RL;Timpson, P;Li, A;Cammareri, P;Ridgway, RA;Morton, JP;Doyle, B;Hegarty, S;Rafferty, M;Murphy, IG;McDermott, EW;Sheahan, K;Pedone, K;Finn, AJ;Groben, PA;Thomas, NE;Hao, H;Carson, C;Norman, JC;Machesky, LM;Gallagher, WM;Jackson, IJ;Van Kempen, L;Beermann, F;Der, C;Larue, L;Welch, HC;Ozanne, BW;Sansom, OJ;
2011
22109529
November 22nd, 2011
United Kingdom
The Beatson Institute for Cancer Research, Glasgow G61 1BD, UK
Inflammation-driven carcinogenesis is mediated through STING
Nature Communications
Ahn, J;Xia, T;Konno, H;Konno, K;Ruiz, P;Barber, GN;
2014
25300616
October 10th, 2014
United States
Department of Cell Biology and Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, Florida 33136, USA
Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia
Developmental Cell
Scholl, FA;Dumesic, PA;Barragan, DI;Harada, K;Bissonauth, V;Charron, J;Khavari, PA;
2007
17419998
April 1st, 2007
United States
Veterans Affairs Palo Alto Healthcare System, Palo Alto, CA 94304, USA
Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits
Developmental Cell
Ferguson, SM;Ferguson, S;Raimondi, A;Paradise, S;Shen, H;Mesaki, K;Ferguson, A;Destaing, O;Ko, G;Takasaki, J;Cremona, O;O' Toole, E;De Camilli, P;
2009
20059951
December 1st, 2009
United States
Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA
TRPC6 channel translocation into phagosomal membrane augments phagosomal function
Proceedings of the National Academy of Sciences of the United States of America
Riazanski, V;Gabdoulkhakova, AG;Boynton, LS;Eguchi, RR;Deriy, LV;Hogarth, DK;LoaÌÇc, N;Oumata, N;Galons, H;Brown, ME;Shevchenko, P;Gallan, AJ;Yoo, SG;Naren, AP;Villereal, ML;Beacham, DW;Bindokas, VP;Birnbaumer, L;Meijer, L;Nelson, DJ;
2015
26604306
November 24th, 2015
United States
Laboratory of Neurobiology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 nelson@uchicago.edu
Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity
Proceedings of the National Academy of Sciences of the United States of America
Sah, R;Mesirca, P;Van den Boogert, M;Rosen, J;Mably, J;Mangoni, ME;Clapham, DE;
2013
23878236
August 1st, 2013
United States
Howard Hughes Medical Institute, Department of Cardiology, Boston Children's Hospital, Boston, MA 02115, USA
Notch3 drives development and progression of cholangiocarcinoma
Proceedings of the National Academy of Sciences of the United States of America
Guest, RV;Boulter, L;Dwyer, BJ;Kendall, TJ;Man, TY;Minnis-Lyons, SE;Lu, WY;Robson, AJ;Gonzalez, SF;Raven, A;Wojtacha, D;Morton, JP;Komuta, M;Roskams, T;Wigmore, SJ;Sansom, OJ;Forbes, SJ;
2016
27791012
October 25th, 2016
United Kingdom
Medical Research Council Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4UU, United Kingdom; Department of Surgery, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, United Kingdom; stuart.forbes@ed.ac.uk
Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer
Proceedings of the National Academy of Sciences of the United States of America
Ahmad, I;Mui, E;Galbraith, L;Patel, R;Tan, EH;Salji, M;Rust, AG;Repiscak, P;Hedley, A;Markert, E;Loveridge, C;van der Weyden, L;Edwards, J;Sansom, OJ;Adams, DJ;Leung, HY;
2016
27357679
July 19th, 2016
United Kingdom
Cancer Research UK Beatson Institute, Bearsden, Glasgow G61 1BD, United Kingdom; Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, United Kingdom; h.leung@beatson.gla.ac.uk
Striosome-dendron bouquets highlight a unique striatonigral circuit targeting dopamine-containing neurons
Proceedings of the National Academy of Sciences of the United States of America
Crittenden, JR;Tillberg, PW;Riad, MH;Shima, Y;Gerfen, CR;Curry, J;Housman, DE;Nelson, SB;Boyden, ES;Graybiel, AM;
2016
27647894
October 4th, 2016
United States
McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139
Identification of cancer initiating cells in K-Ras driven lung adenocarcinoma
Proceedings of the National Academy of Sciences of the United States of America
Mainardi, S;Mijimolle, N;Francoz, S;Vicente-Due̱as, C;SÃŒÃnchez-GarcÃŒ_a, I;Barbacid, M;
2014
24367082
January 1st, 2014
Spain
Molecular Oncology Programme, Centro Nacional de Investigaciones OncolÌ_gicas, 28029 Madrid, Spain
Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation
Proceedings of the National Academy of Sciences of the United States of America
Castillo, EF;Dekonenko, A;Arko-Mensah, J;Mandell, MA;Dupont, N;Jiang, S;Delgado-Vargas, M;Timmins, GS;Bhattacharya, D;Yang, H;Hutt, J;Lyons, CR;Dobos, KM;Deretic, V;
2012
23093667
November 13th, 2012
United States
Department of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
HER2 overcomes PTEN (loss)-induced senescence to cause aggressive prostate cancer
Proceedings of the National Academy of Sciences of the United States of America
Ahmad, I;Patel, R;Singh, LB;Nixon, C;Seywright, M;Barnetson, RJ;Brunton, VG;Muller, WJ;Edwards, J;Sansom, OJ;Leung, HY;
2011
21930937
September 27th, 2011
United Kingdom
Beatson Institute for Cancer Research, Glasgow G61 1BD, United Kingdom
Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice
Proceedings of the National Academy of Sciences of the United States of America
Laposa, RR;Huang, EJ;Cleaver, JE;
2007
17229834
January 23rd, 2007
United States
Department of Dermatology and Cancer Center, University of California, San Francisco, CA 94143-0808, USA
Cystic fibrosis transmembrane conductance regulator with a shortened R domain rescues the intestinal phenotype of CFTR-/- mice
Proceedings of the National Academy of Sciences of the United States of America
Ostedgaard, LS;Meyerholz, DK;Vermeer, DW;Karp, PH;Schneider, L;Sigmund, CD;Welsh, MJ;
2011
21285372
February 15th, 2011
United States
Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
The preproghrelin gene is required for the normal integration of thermoregulation and sleep in mice
Proceedings of the National Academy of Sciences of the United States of America
Szentirmai, E;KapÃŒÃs, L;Sun, Y;Smith, RG;Krueger, JM;
2009
19666521
August 18th, 2009
United States
Sleep and Performance Research Center, Department of Veterinary and Comparative Anatomy, Pharmacology, and Physiology, Washington State University, Pullman, WA 99164, USA
CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo
Proceedings of the National Academy of Sciences of the United States of America
Zhu, JG;Ochalek, JT;Kaufmann, M;Jones, G;Deluca, HF;
2013
24019477
September 24th, 2013
United States
Department of Biochemistry, University of Wisconsin, Madison, WI 53706
STING manifests self DNA-dependent inflammatory disease
Proceedings of the National Academy of Sciences of the United States of America
Ahn, J;Gutman, D;Saijo, S;Barber, GN;
2012
23132945
November 20th, 2012
United States
Department of Cell Biology and Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, FL 33136, USA
A human IL10 BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome
Proceedings of the National Academy of Sciences of the United States of America
Ranatunga, D;Hedrich, CM;Wang, F;McVicar, DW;Nowak, N;Joshi, T;Feigenbaum, L;Grant, LR;StÌ_ger, S;Bream, JH;
2009
19805095
October 1st, 2009
United States
W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205-1901, USA
Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst
Proceedings of the National Academy of Sciences of the United States of America
Ramsey, IS;Ruchti, E;Kaczmarek, JS;Clapham, DE;
2009
19372380
May 1st, 2009
United States
Howard Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, and Department of Cardiovascular Research, Manton Center for Orphan Disease, Children's Hospital, 320 Longwood Avenue, Boston, MA 02115, USA
Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine ë_-thalassemia
Blood
Suragani, RN;Cawley, SM;Li, R;Wallner, S;Alexander, MJ;Mulivor, AW;Gardenghi, S;Rivella, S;Grinberg, AV;Pearsall, RS;Kumar, R;
2014
24795345
June 19th, 2014
United States
Acceleron Pharma, Cambridge, MA; and
FGF signaling facilitates postinjury recovery of mouse hematopoietic system
Blood
Zhao, M;Ross, JT;Itkin, T;Perry, JM;Venkatraman, A;Haug, JS;Hembree, MJ;Deng, CX;Lapidot, T;He, XC;Li, L;
2012
22802336
August 30th, 2012
United States
Stowers Institute for Medical Research, Kansas City, MO 64110, USA
Targeting vasculogenesis to prevent progression in multiple myeloma
Leukemia
Moschetta, M;Mishima, Y;Kawano, Y;Manier, S;Paiva, B;Palomera, L;Aljawai, Y;Calcinotto, A;Unitt, C;Sahin, I;Sacco, A;Glavey, S;Shi, J;Reagan, MR;Prosper, F;Bellone, M;Chesi, M;Bergsagel, LP;Vacca, A;Roccaro, AM;Ghobrial, IM;
2016
26859080
May 1st, 2016
United States
Medical Oncology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA, USA
p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia
Cancer Research
Hendley, AM;Wang, YJ;Polireddy, K;Alsina, J;Ahmed, I;Lafaro, KJ;Zhang, H;Roy, N;Savidge, SG;Cao, Y;Hebrok, M;Maitra, A;Reynolds, AB;Goggins, M;Younes, M;Iacobuzio-Donahue, CA;Leach, SD;Bailey, JM;
2016
27032419
June 1st, 2016
United States
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland. The McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland. The David Rubenstein Pancreatic Cancer Research Center, Memorial Sloan Kettering Cancer Center, New York, New York. Jennifer.M.Bailey@uth.tmc.edu
Deregulated estrogen receptor alpha and p53 heterozygosity collaborate in the development of mammary hyperplasia
Cancer Research
DÌ_az-Cruz, ES;Furth, PA;
2010
20466998
May 15th, 2010
United States
Departments of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia 20057, USA
STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma
Cancer Research
Lau, J;Ilkhanizadeh, S;Wang, S;Miroshnikova, YA;Salvatierra, NA;Wong, RA;Schmidt, C;Weaver, VM;Weiss, WA;Persson, AI;
2015
26282165
October 15th, 2015
United States
Department of Pediatrics, University of California, San Francisco, San Francisco, California. Department of Neurology, Neurological Surgery and Brain Tumor Research Center, University of California, San Francisco, San Francisco, California. Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California. waweiss@gmail.com
Obesity promotes breast cancer by CCL2-mediated macrophage recruitment and angiogenesis
Cancer Research
Arendt, LM;McCready, J;Keller, PJ;Baker, DD;Naber, SP;Seewaldt, V;Kuperwasser, C;
2013
23959857
October 1st, 2013
United States
Authors' Affiliations: Developmental, Molecular, and Chemical Biology Department, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine; Molecular Oncology Research Institute and Medical Oncology and Department of Pathology, Tufts Medical Center, Boston, Massachusetts; and Departments of Medicine, Duke University, Durham, North Carolina
A novel mouse model that develops spontaneous arthritis and is predisposed towards atherosclerosis
Annals of Rheumatic Diseases
Rose, S;Eren, M;Murphy, S;Zhang, H;Thaxton, CS;Chowaniec, J;Waters, EA;Meade, TJ;Vaughan, DE;Perlman, H;
2013
22736097
January 1st, 2013
United States
Department of Medicine, Northwestern UniversityFeinberg School of Medicine, Chicago, IL, USA
The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis
Oncogene
Park, JM;Wu, T;Cyr, AR;Woodfield, GW;De Andrade, JP;Spanheimer, PM;Li, T;Sugg, SL;Lal, G;Domann, FE;Zhang, W;Weigel, RJ;
2015
25772240
December 10th, 2015
United States
Department of Surgery, University of Iowa, Iowa City, IA, USA
In vivo oncogenic conflict triggered by co-existing KRAS and EGFR activating mutations in lung adenocarcinoma
Oncogene
Ambrogio, C;Barbacid, M;SantamarÌ_a, D;
2016
27775074
October 24th, 2016
Spain
Experimental Oncology, Molecular Oncology Programme, Centro Nacional de Investigaciones OncolÌ_gicas (CNIO), Madrid, Spain
TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis
Oncogene
Cyr, AR;Kulak, MV;Park, JM;Bogachek, MV;Spanheimer, PM;Woodfield, GW;White-Baer, LS;O'Malley, YQ;Sugg, SL;Olivier, AK;Zhang, W;Domann, FE;Weigel, RJ;
2015
24469049
January 22nd, 2015
United States
1] Department of Surgery, University of Iowa, Iowa City, IA, USA [2] Department of Radiation Oncology, University of Iowa, Iowa City, IA, USA
Mek1/2 gene dosage determines tissue response to oncogenic Ras signaling in the skin
Oncogene
Scholl, FA;Dumesic, PA;Barragan, DI;Charron, J;Khavari, PA;
2009
19198628
March 26th, 2009
United States
Department of Dermatology, Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305, USA
Functions of TAp63 and p53 in restraining the development of metastatic cancer
Oncogene
Tan, EH;Morton, JP;Timpson, P;Tucci, P;Melino, G;Flores, ER;Sansom, OJ;Vousden, KH;Muller, PA;
2014
23873029
June 19th, 2014
United Kingdom
Cancer Research UK Beatson Institute, Glasgow, UK
p53 mutations cooperate with oncogenic Kras to promote adenocarcinoma from pancreatic ductal cells
Oncogene
Bailey, JM;Hendley, AM;Lafaro, KJ;Pruski, MA;Jones, NC;Alsina, J;Younes, M;Maitra, A;McAllister, F;Iacobuzio-Donahue, CA;Leach, SD;
2016
26592447
August 11th, 2016
United States
Department of Internal Medicine, Division of Gastroenterology, Hepatology and Nutrition, The University of Texas Health Science Center at Houston, Houston, TX, USA
C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptor
Elife
Azevedo, AW;Doan, T;Moaven, H;Sokal, I;Baameur, F;Vishnivetskiy, SA;Homan, KT;Tesmer, JJ;Gurevich, VV;Chen, J;Rieke, F;
2015
25910054
April 24th, 2015
United States
Department of Physiology and Biophysics, University of Washington, Seattle, United States
Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel
Elife
Lana-Elola, E;Watson-Scales, S;Slender, A;Gibbins, D;Martineau, A;Douglas, C;Mohun, T;Fisher, EM;Tybulewicz, VLj;
2016
26765563
January 14th, 2016
United Kingdom
The Francis Crick Institute, London, United Kingdom
Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration
Elife
Kurihara, T;Westenskow, PD;Gantner, ML;Usui, Y;Schultz, A;Bravo, S;Aguilar, E;Wittgrove, C;Friedlander, MSh;Paris, LP;Chew, E;Siuzdak, G;Friedlander, M;
2016
26978795
March 15th, 2016
United States
Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, United States
Sex differences in cerebellar synaptic transmission and sex-specific responses to autism-linked Gabrb3 mutations in mice
Elife
Mercer, AA;Palarz, KJ;Tabatadze, N;Woolley, CS;Raman, IM;
2016
27077953
April 14th, 2016
United States
Northwestern University Interdepartmental Neuroscience Program, Northwestern University, Evanston, United States
Kindlin1 regulates microtubule function to ensure normal mitosis
Journal of Molecular Cell Biology
Patel, H;Stavrou, I;Shrestha, RL;Draviam, V;Frame, MC;Brunton, VG;
2016
26993041
August 1st, 2016
United Kingdom
Edinburgh Cancer Research Centre, Institute of Genetics & Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK h.patel@ed.ac.uk
Matrix metalloproteinase-20 mediates dental enamel biomineralization by preventing protein occlusion inside apatite crystals
Biomaterials
Prajapati, S;Tao, J;Ruan, Q;De Yoreo, JJ;Moradian-Oldak, J;
2016
26513418
January 1st, 2016
United States
University of Southern California, Herman Ostrow School of Dentistry, Division of Biomedical Sciences, Center for Craniofacial Molecular Biology, Los Angeles, CA 90033, USA
Disrupted Cortical State Regulation in a Rat Model of Fragile X Syndrome
Cerebral Cortex
Berzhanskaya, J;Phillips, MA;Gorin, A;Lai, C;Shen, J;Colonnese, MT;
2016
26733529
January 5th, 2016
United States
Department of Pharmacology and Physiology and Institute for Neuroscienc,2300 Eye St NW, Ross Hall 640, Washington, DC 20037, USA.
Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy
EMBO Molecular Medicine
Miller, BW;Morton, JP;Pinese, M;Saturno, G;Jamieson, NB;McGhee, E;Timpson, P;Leach, J;McGarry, L;Shanks, E;Bailey, P;Chang, D;Oien, K;Karim, S;Au, A;Steele, C;Carter, CR;McKay, C;Anderson, K;Evans, TR;Marais, R;Springer, C;Biankin, A;Erler, JT;Sansom, OJ;
2015
26077591
June 15th, 2015
Denmark
Biotech Research & Innovation Centre (BRIC), University of Copenhagen, Copenhagen (UCPH), Denmark o.sansom@beatson.gla.ac.uk
SPRY2 loss enhances ErbB trafficking and PI3K/AKT signalling to drive human and mouse prostate carcinogenesis
EMBO Molecular Medicine
Gao, M;Patel, R;Ahmad, I;Fleming, J;Edwards, J;McCracken, S;Sahadevan, K;Seywright, M;Norman, J;Sansom, O;Leung, HY;
2012
22649008
August 1st, 2012
United Kingdom
Beatson Institute for Cancer Research, Glasgow, UK
p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium
EMBO Molecular Medicine
Cole, AM;Ridgway, RA;Derkits, SE;Parry, L;Barker, N;Clevers, H;Clarke, AR;Sansom, OJ;
2010
20976827
November 1st, 2010
United Kingdom
Beatson Institute of Cancer Research, Glasgow, UK
Differential role of lipocalin 2 during immune complex-mediated acute and chronic inflammation in mice
Arthritis & Rheumatology
Shashidharamurthy, R;Machiah, D;Aitken, JD;Putty, K;Srinivasan, G;Chassaing, B;Parkos, CA;Selvaraj, P;Vijay-Kumar, M;
2013
23280250
April 1st, 2013
United States
Department of Pharmaceutical Sciences, Philadelphia College of Osteopathic Medicine, Suwanee, Georgia 30024, USA
Requirement of myeloid cell-specific Fas expression for prevention of systemic autoimmunity in mice
Arthritis & Rheumatology
Cuda, CM;Agrawal, H;Misharin, AV;Haines, GK;Hutcheson, J;Weber, E;Schoenfeldt, JA;Mohan, C;Pope, RM;Perlman, H;
2012
22143975
March 1st, 2012
United States
Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Role of ë_4* Nicotinic Acetylcholine Receptors in the Habenulo-Interpeduncular Pathway in Nicotine Reinforcement in Mice
Neuropsychopharmacology
Harrington, L;Vi̱als, X;Herrera-SolÌ_s, A;Flores, A;Morel, C;Tolu, S;Faure, P;Maldonado, R;Maskos, U;Robledo, P;
2016
26585290
June 1st, 2016
Spain
Unit̩ Neurobiologie Int̩grative des Syst̬mes Cholinergiques, D̩partement de Neuroscience, Institut Pasteur, Paris Cedex, France
Forebrain-specific CRF overproduction during development is sufficient to induce enduring anxiety and startle abnormalities in adult mice
Neuropsychopharmacology
Toth, M;Gresack, JE;Bangasser, DA;Plona, Z;Valentino, RJ;Flandreau, EI;Mansuy, IM;Merlo-Pich, E;Geyer, MA;Risbrough, VB;
2014
24326400
May 1st, 2014
United States
1] Department of Psychiatry, University of California San Diego, La Jolla, CA, USA [2] Center of Excellence for Stress and Mental Health, Veterans Affairs Hospital, La Jolla, CA, USA
NADPH Oxidase-Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes
Small
Sun, B;Wang, X;Ji, Z;Wang, M;Liao, YP;Chang, CH;Li, R;Zhang, H;Nel, AE;Xia, T;
2015
25581126
May 6th, 2015
United States
Nature Methods,5,267,2008
CXCR2 inhibition suppresses acute and chronic pancreatic inflammation
Journal of Pathology
Steele, CW;Karim, SA;Foth, M;Rishi, L;Leach, JD;Porter, RJ;Nixon, C;Jeffry Evans, TR;Carter, CR;Nibbs, RJ;Sansom, OJ;Morton, JP;
2015
25950520
September 1st, 2015
United Kingdom
Cancer Research UK Beatson Institute, Glasgow, UK
Fibroblast growth factor receptor 3 activation plays a causative role in urothelial cancer pathogenesis in cooperation with Pten loss in mice
Journal of Pathology
Foth, M;Ahmad, I;van Rhijn, BW;van der Kwast, T;Bergman, AM;King, L;Ridgway, R;Leung, HY;Fraser, S;Sansom, OJ;Iwata, T;
2014
24519156
June 1st, 2014
United Kingdom
School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK; Beatson Institute for Cancer Research, Glasgow, UK
Vertebrate Host Susceptibility to Heartland Virus
Emerging Infectious Diseases
Lauth, AM;Calvert, AE;Root, JJ;Gidlewski, T;Bird, BH;Bowen, RA;Muehlenbachs, A;Zaki, SR;Brault, AC;
2016
December 1st, 2016
United States
Centers for Disease Control and Prevention, 3156 Rampart Rd, Foothills Campus, Fort Collins, CO 80521, USA
Telomere-Internal Double-Strand Breaks Are Repaired by Homologous Recombination and PARP1/Lig3-Dependent End-Joining
Cell Reports
Doksani, Y;de Lange, T;
2016
27806302
November 1st, 2016
European Union
Laboratory for Cell Biology and Genetics, Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
Expression of BCR/ABL p210 from a knockin allele enhances bone marrow engraftment without inducing neoplasia
Cell Reports
Foley, SB;Hildenbrand, ZL;Soyombo, AA;Magee, JA;Wu, Y;Oravecz-Wilson, KI;Ross, TS;
2013
24095735
October 17th, 2013
United States
Department of Internal Medicine and Cancer Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Role of angiopoietin-2 in adaptive tumor resistance to VEGF signaling blockade
Cell Reports
Rigamonti, N;Kadioglu, E;Keklikoglou, I;Wyser Rmili, C;Leow, CC;De Palma, M;
2014
25088418
August 1st, 2014
Switzerland
Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ìäcole Polytechnique FÌ©dÌ©rale de Lausanne (EPFL), 1015åÊLausanne, Switzerland
Pten loss in Olig2 expressing neural progenitor cells and oligodendrocytes leads to interneuron dysplasia and leukodystrophy
Stem Cells
Maire, CL;Ramkissoon, S;Hayashi, M;Haidar, S;Ramkissoon, L;DiTomaso, E;Ligon, KL;
2014
24395742
January 1st, 2014
United States
Department of Medical Oncology, Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA
Target-derived neurotrophins coordinate transcription and transport of bclw to prevent axonal degeneration
Journal of Neuroscience
Cosker, KE;Pazyra-Murphy, MF;Fenstermacher, SJ;Segal, RA;
2013
23516285
March 20th, 2013
United States
Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA
Fatty Acid-Binding Protein 5 at the Blood-Brain Barrier Regulates Endogenous Brain Docosahexaenoic Acid Levels and Cognitive Function
Journal of Neuroscience
Pan, Y;Short, JL;Choy, KH;Zeng, AX;Marriott, PJ;Owada, Y;Scanlon, MJ;Porter, CJ;Nicolazzo, JA;
2016
27852782
November 16th, 2016
United States
Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia
The Angelman syndrome protein Ube3a/E6AP is required for Golgi acidification and surface protein sialylation
Journal of Neuroscience
Condon, KH;Ho, J;Robinson, CG;Hanus, C;Ehlers, MD;
2013
23447592
February 27th, 2013
United States
Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
Homeostatic responses fail to correct defective amygdala inhibitory circuit maturation in fragile X syndrome
Journal of Neuroscience
Vislay, RL;Martin, BS;Olmos-Serrano, JL;Kratovac, S;Nelson, DL;Corbin, JG;Huntsman, MM;
2013
23616559
April 24th, 2013
United States
Center for Neuroscience Research, Children's National Medical Center, Washington, DC 20010, USA
PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons
Journal of Neuroscience
Ying, SW;Tibbs, GR;Picollo, A;Abbas, SY;Sanford, RL;Accardi, A;Hofmann, F;Ludwig, A;Goldstein, PA;
2011
21753018
July 13th, 2011
United States
Department of Anesthesiology, Weill Cornell Medical College, New York, New York 10065, USA
Mature mice lacking Rbl2/p130 gene have supernumerary inner ear hair cells and supporting cells
Journal of Neuroscience
Rocha-Sanchez, SM;Scheetz, LR;Contreras, M;Weston, MD;Korte, M;McGee, J;Walsh, EJ;
2011
21677172
June 15th, 2011
United States
Department of Oral Biology, Creighton University School of Dentistry, Omaha, Nebraska 68178, USA
The p38ë± MAPK regulates microglial responsiveness to diffuse traumatic brain injury
Journal of Neuroscience
Bachstetter, AD;Rowe, RK;Kaneko, M;Goulding, D;Lifshitz, J;Van Eldik, LJ;
2013
23554495
April 1st, 2013
United States
Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky 40536, USA
PPARë_ recruitment to active ERK during memory consolidation is required for Alzheimer''s disease-related cognitive enhancement
Journal of Neuroscience
Jahrling, JB;Hernandez, CM;Denner, L;Dineley, KT;
2014
24623782
March 12th, 2014
United States
Mitchell Center for Neurodegenerative Diseases, Departments of Neurology and Internal Medicine, Division of Endocrinology, McCoy Stem Cells and Diabetes Mass Spectrometry Research Laboratory, Sealy Center for Molecular Medicine, and Institute for Translational Science, University of Texas Medical Branch, Galveston, Texas 77555
Sensory neuropathy attributable to loss of Bcl-w
Journal of Neuroscience
Courchesne, SL;Karch, C;Pazyra-Murphy, MF;Segal, RA;
2011
21289171
February 1st, 2011
United States
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA
Circuit-specific intracortical hyperconnectivity in mice with deletion of the autism-associated Met receptor tyrosine kinase
Journal of Neuroscience
Qiu, S;Anderson, CT;Levitt, P;Shepherd, GM;
2011
21490227
April 13th, 2011
United States
Zilkha Neurogenetics Institute, Department of Cell and Neurobiology, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
Dendritic HCN2 channels constrain glutamate-driven excitability in reticular thalamic neurons
Journal of Neuroscience
Ying, SW;Jia, F;Abbas, SY;Hofmann, F;Ludwig, A;Goldstein, PA;
2007
17687049
August 1st, 2007
United States
C. V. Starr Laboratory for Molecular Neuropharmacology, Department of Anesthesiology, Weill Medical College, Cornell University, New York, New York 10021, USA
A new mouse model for stationary night blindness with mutant Slc24a1 explains the pathophysiology of the associated human disease
Human Molecular Genetics
Vinberg, F;Wang, T;Molday, RS;Chen, J;Kefalov, VJ;
2015
26246500
October 15th, 2015
United States
Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA
CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy
Human Molecular Genetics
Ljungberg, MC;Ali, YO;Zhu, J;Wu, CS;Oka, K;Zhai, RG;Lu, HC;
2012
22027994
January 15th, 2012
United States
The Cain Foundation Laboratories, Jan and Dan Duncan Neurological Research Institute at Texas Children‰Ûªs Hospital, Baylor College of Medicine, Houston, TX 77030, USA
Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis
Human Molecular Genetics
Husson, H;Moreno, S;Smith, LA;Smith, MM;Russo, RJ;Pitstick, R;Sergeev, M;Ledbetter, SR;Bukanov, NO;Lane, M;Zhang, K;Billot, K;Carlson, G;Shah, J;Meijer, L;Beier, DR;Ibraghimov-Beskrovnaya, O;
2016
27053712
June 1st, 2016
United States
Department of Rare Diseases, Sanofi-Genzyme R&D Center, 49 New York Avenue, Framingham, MA 01701, USA
Lipid-enriched diet rescues lethality and slows down progression in a murine model of VCP-associated disease
Human Molecular Genetics
Llewellyn, KJ;Nalbandian, A;Jung, KM;Nguyen, C;Avanesian, A;Mozaffar, T;Piomelli, D;Kimonis, VE;
2014
24158850
March 1st, 2014
United States
Department of Pediatrics, Division of Genetics and Metabolism
Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease
Human Molecular Genetics
Natoli, TA;Husson, H;Rogers, KA;Smith, LA;Wang, B;Budman, Y;Bukanov, NO;Ledbetter, SR;Klinger, KW;Leonard, JP;Ibraghimov-Beskrovnaya, O;
2012
22563011
August 1st, 2012
United States
Department of Cell Biology, Genzyme Corporation, Framingham, MA 01701, USA
Glycogen accumulation underlies neurodegeneration and autophagy impairment in Lafora disease
Human Molecular Genetics
Duran, J;Gruart, A;GarcÌ_a-Rocha, M;Delgado-GarcÌ_a, JM;Guinovart, JJ;
2014
24452334
June 15th, 2014
Spain
Institute for Research in Biomedicine (IRB Barcelona), Barcelona 08028, Spain Centro de InvestigaciÌ_n BiomÌ©dica en Red de Diabetes y Enfermedades MetabÌ_licas Asociadas (CIBERDEM), Barcelona 08017, Spain Department of Biochemistry and Molecular Biology, University of Barcelona, Barcelona 08028, Spain
AKT regulates NPM dependent ARF localization and p53mut stability in tumors
Oncotarget
Hamilton, G;Abraham, AG;Morton, J;Sampson, O;Pefani, DE;Khoronenkova, S;Grawenda, A;Papaspyropoulos, A;Jamieson, N;McKay, C;Sansom, O;Dianov, GL;O'Neill, E;
2014
25071014
August 15th, 2014
United Kingdom
Cancer Research UK/MRC Oxford Institute, Department of Oncology, University of Oxford, Old Road Campus, Roosevelt Drive, UK
The role of apoptosis in immune hyporesponsiveness following AAV8 liver gene transfer
Molecular Therapy
Faust, SM;Bell, P;Zhu, Y;Sanmiguel, J;Wilson, JM;
2013
24126962
December 1st, 2013
United States
Department of Pathology and Laboratory Medicine, Gene Therapy Program, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling
Journal of Investigative Dermatology
Pawlikowski, JS;Brock, C;Chen, SC;Al-Olabi, L;Nixon, C;McGregor, F;Paine, S;Chanudet, E;Lambie, W;Holmes, WM;Mullin, JM;Richmond, A;Wu, H;Blyth, K;King, A;Kinsler, VA;Adams, PD;
2015
26178707
November 1st, 2015
United Kingdom
Institute of Cancer Sciences, University of Glasgow, Glasgow, UK
ë±5 and ë±v integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo
Development
Turner, CJ;Badu-Nkansah, K;Crowley, D;van der Flier, A;Hynes, RO;
2015
25670798
February 15th, 2015
United States
Howard Hughes Medical Institute, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle
Development
Gokhin, DS;Ochala, J;Domenighetti, AA;Fowler, VM;
2015
26586224
December 15th, 2015
United States
Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037, USA velia@scripps.edu
Phenotypic analysis of mice completely lacking netrin 1
Development
Yung, AR;Nishitani, AM;Goodrich, LV;
2015
26395479
November 1st, 2015
United States
Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA
Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development
Development
van der Flier, A;Badu-Nkansah, K;Whittaker, CA;Crowley, D;Bronson, RT;Lacy-Hulbert, A;Hynes, RO;
2010
20570943
July 1st, 2010
United States
Howard Hughes Medical Institute, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development
Development
Mao, Y;Mulvaney, J;Zakaria, S;Yu, T;Morgan, KM;Allen, S;Basson, MA;Francis-West, P;Irvine, KD;
2011
21303848
March 1st, 2011
United Kingdom
Howard Hughes Medical Institute, Waksman Institute and Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ 08854, USA
Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation
Development
Ma, Y;Li, A;Faller, WJ;Libertini, S;Fiorito, F;Gillespie, DA;Sansom, OJ;Yamashiro, S;Machesky, LM;
2013
23633513
May 1st, 2013
United Kingdom
Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK
The neuron-specific interleukin-1 receptor accessory protein is required for homeostatic sleep and sleep responses to influenza viral challenge in mice
Brain Behavior and Immunity
Davis, CJ;Dunbrasky, D;Oonk, M;Taishi, P;Opp, MR;Krueger, JM;
2015
25449578
July 1st, 2015
United States
College of Medical Sciences and the Sleep and Performance Research Center, Washington State University Spokane, Spokane, WA 99210, United States
Sickness behaviour after lipopolysaccharide treatment in ghrelin deficient mice
Brain Behavior and Immunity
Szentirmai, Ìä;Krueger, JM;
2014
24309634
February 1st, 2014
United States
Washington, Wyoming, Alaska, Montana and Idaho (WWAMI) Medical Education Program, Washington State University, Spokane, WA, USA; Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, WA, USA; Sleep and Performance Research Center, Washington State University, Spokane, WA, USA
Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow aging
Aging Cell
Arum, O;Boparai, RK;Saleh, JK;Wang, F;Dirks, AL;Turner, JG;Kopchick, JJ;Liu, JL;Khardori, RK;Bartke, A;
2014
25244225
December 1st, 2014
United States
Department of Internal Medicine, Southern Illinois University-School of Medicine, Springfield, IL, 62794, USA
Sensitization of nociceptive spinal neurons contributes to pain in a transgenic model of sickle cell disease
Pain
Cataldo, G;Rajput, S;Gupta, K;Simone, DA;
2015
25630029
April 1st, 2015
United States
aDepartment of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN, USA bDivision of Hematology, Oncology and Transplantation, Department of Medicine, Vascular Biology Center, University of Minnesota, Minneapolis, MN, USA
Optogenetic release of norepinephrine from cardiac sympathetic neurons alters mechanical and electrical function
Cardiovascular Research
Wengrowski, AM;Wang, X;Tapa, S;Posnack, NG;Mendelowitz, D;Kay, MW;
2015
25514932
February 1st, 2015
United States
Department of Biomedical Engineering, The George Washington University, Phillips Hall, Room 607, 801 22nd Street NW, Washington, DC 20052, USA Department of Pharmacology and Physiology, The George Washington University, Washington, DC, USA
NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis
Free Radical Biology and Medicine
Di Marco, E;Gray, SP;Kennedy, K;Szyndralewiez, C;Lyle, AN;Lass̬gue, B;Griendling, KK;Cooper, ME;Schmidt, HH;Jandeleit-Dahm, KA;
2016
27445103
August 1st, 2016
Australia
Diabetic Complications Division, Baker IDI Heart & Diabetes Institute, Melbourne, Australia; Department of Medicine, Monash University, Melbourne, Australia
Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury
Free Radical Biology and Medicine
Mukhopadhyay, P;HorvÃŒÃth, B;Rajesh, M;Matsumoto, S;Saito, K;BÃŒÃtkai, S;Patel, V;Tanchian, G;Gao, RY;Cravatt, BF;HaskÃŒ_, G;Pacher, P;
2011
21070851
January 1st, 2011
United States
Laboratory of Physiologic Studies, National Institute on Alcohol Abuse and Alcoholism, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Chk1 is essential for the development of murine epidermal melanocytes
Pigment Cell and Melanoma Research
Smith, J;Larue, L;Gillespie, DA;
2013
23557358
July 1st, 2013
United Kingdom
Beatson Institute for Cancer Research, Glasgow, UK
Differential effects of NOX4 and NOX1 on immune cell-mediated inflammation in the aortic sinus of diabetic ApoE-/- mice
Clinical Science
Di Marco, E;Gray, SP;Chew, P;Kennedy, K;Cooper, ME;Schmidt, HH;Jandeleit-Dahm, KA;
2016
27190136
August 1st, 2016
Australia
Diabetic Complications Division, Baker IDI Heart & Diabetes Institute, Melbourne, Australia Department of Medicine, Monash University, Melbourne, Australia
Use of a genetically engineered mouse model as a preclinical tool for HER2 breast cancer
Disease Models and Mechanisms
Creedon, H;Balderstone, LA;Muir, M;Balla, J;Gomez-Cuadrado, L;Tracey, N;Loane, J;Klinowska, T;Muller, WJ;Brunton, VG;
2016
26721874
February 1st, 2016
United Kingdom
Edinburgh Cancer Research UK Centre, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK
CK2 activity is required for the interaction of FGF14 with voltage-gated sodium channels and neuronal excitability
FASEB Journal
Hsu, WC;Scala, F;Nenov, MN;Wildburger, NC;Elferink, H;Singh, AK;Chesson, CB;Buzhdygan, T;Sohail, M;Shavkunov, AS;Panova, NI;Nilsson, CL;Rudra, JS;Lichti, CF;Laezza, F;
2016
26917740
June 1st, 2016
United States
Department of Pharmacology and Toxicology, Mitchell Center for Neurodegenerative Diseases, Center for Addiction Research, and Center for Biomedical Engineering, University of Texas Medical Branch, Galveston, Texas, USA
Sustained nitric oxide (NO)-releasing compound reverses dysregulated NO signal transduction in priapism
FASEB Journal
Lagoda, G;Sezen, SF;Hurt, KJ;Cabrini, MR;Mohanty, DK;Burnett, AL;
2014
24076963
January 1st, 2014
United States
1Department of Urology, The Johns Hopkins Hospital, 600 N. Wolfe St., Marburg 407, Baltimore, MD 21287-2411, USA
Proceedings of the Second Shanthi V. Sitaraman Intestinal Pathobiology Symposium
Inflammory Bowel Disorder Journal
Etienne-Mesmin, L;Wang, T;Viennois, E;Chassaing, B;Gewirtz, AT;Merlin, D;
2015
26389819
August 1st, 2015
United States
Center for Inflammation, Immunity, and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia
Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor
International Journal of Obesity (Lond)
Hoang-Yen Tran, D;Hoang-Ngoc Tran, D;Mattai, SA;Sallam, T;Ortiz, C;Lee, EC;Robbins, L;Ho, S;Lee, JE;Fisseha, E;Shieh, C;Sideri, A;Shih, DQ;Fleshner, P;McGovern, DP;Vu, M;Hing, TC;Bakirtzi, K;Cheng, M;Su, B;Law, I;Karagiannides, I;Targan, SR;Gallo, RL;Li, Z;Koon, HW;
2016
27163748
September 1st, 2016
United States
Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USA
Intrauterine group A streptococcal infections are exacerbated by prostaglandin E2
Journal of Immunology
Mason, KL;Rogers, LM;Soares, EM;Bani-Hashemi, T;Erb Downward, J;Agnew, D;Peters-Golden, M;Weinberg, JB;Crofford, LJ;Aronoff, DM;
2013
23913961
September 1st, 2013
United States
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI 48109, USA
The class A scavenger receptor, macrophage receptor with collagenous structure, is the major phagocytic receptor for Clostridium sordellii expressed by human decidual macrophages
Journal of Immunology
Thelen, T;Hao, Y;Medeiros, AI;Curtis, JL;Serezani, CH;Kobzik, L;Harris, LH;Aronoff, DM;
2010
20810988
October 1st, 2010
United States
Molecular, Cellular, and Developmental Biology Graduate Program, Eastern Michigan University, Ypsilanti, MI 48197, USA
Characterization of human antiviral adaptive immune responses during hepatotropic virus infection in HLA-transgenic human immune system mice
Journal of Immunology
Billerbeck, E;Horwitz, JA;Labitt, RN;Donovan, BM;Vega, K;Budell, WC;Koo, GC;Rice, CM;Ploss, A;
2013
23833235
August 15th, 2013
United States
Laboratory of Virology and Infectious Disease, Center for the Study of Hepatitis C, The Rockefeller University, New York, NY 10065, USA
Intrinsic self-DNA triggers inflammatory disease dependent on STING
Journal of Immunology
Ahn, J;Ruiz, P;Barber, GN;
2014
25261479
November 1st, 2014
United States
Department of Cell Biology, University of Miami Miller School of Medicine, Miami, FL 33136; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136; and
Beta1 integrin is an adhesion protein for sperm binding to eggs
ACS Chemical Biology
Baessler, KA;Lee, Y;Sampson, NS;
2009
19338281
May 15th, 2009
United States
Biochemistry and Structural Biology Graduate Program, Stony Brook University, Stony Brook, NY 11794, USA
Microglial p38ë± MAPK is critical for LPS-induced neuron degeneration, through a mechanism involving TNFë±
Molecular Neurodegeneration
Xing, B;Bachstetter, AD;Van Eldik, LJ;
2011
22185458
December 20th, 2011
United States
Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA
Fibroblast Growth Factor 14 Modulates the Neurogenesis of Granule Neurons in the Adult Dentate Gyrus
Molecular Neurobiology
Alshammari, MA;Alshammari, TK;Nenov, MN;Scala, F;Laezza, F;
2016
26687232
December 1st, 2016
United States
Mitchell Center for Neurodegenerative Diseases, The University of Texas Medical Branch, Galveston, TX, USA
Role of ERalpha in the differential response of Stat5a loss in susceptibility to mammary preneoplasia and DMBA-induced carcinogenesis
Carcinogenesis
Miermont, AM;Parrish, AR;Furth, PA;
2010
20181624
June 1st, 2010
United States
Department of Oncology, Georgetown University, Washington, DC 20007, USA
NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium
Journal of Molecular and Cellular Cardiology
White, MP;Theodoris, CV;Liu, L;Collins, WJ;Blue, KW;Lee, JH;Meng, X;Robbins, RC;Ivey, KN;Srivastava, D;
2015
25871831
July 1st, 2015
United States
Gladstone Institute of Cardiovascular Disease and University of California, San Francisco, USA
Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington''s disease
Neurobiology of Disease
Swarnkar, S;Chen, Y;Pryor, WM;Shahani, N;Page, DT;Subramaniam, S;
2015
26048156
October 1st, 2015
United States
Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida 33458, USA
Mitochondrial dysfunction in an Opa1(Q285STOP) mouse model of dominant optic atrophy results from Opa1 haploinsufficiency
Cell Death Discovery
Kushnareva, Y;Seong, Y;Andreyev, AY;Kuwana, T;Kiosses, WB;Votruba, M;Newmeyer, DD;
2016
27468686
July 28th, 2016
United States
Immune Regulation, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA
Protease induced plasticity: matrix metalloproteinase-1 promotes neurostructural changes through activation of protease activated receptor 1
Scientific Reports
Allen, M;Ghosh, S;Ahern, GP;Villapol, S;Maguire-Zeiss, KA;Conant, K;
2016
27762280
October 20th, 2016
United States
Interdisciplinary Program in Neuroscience, Georgetown University, Washington, DC, USA
Electroacupuncture in conscious free-moving mice reduces pain by ameliorating peripheral and central nociceptive mechanisms
Scientific Reports
Wang, Y;Lei, J;Gupta, M;Peng, F;Lam, S;Jha, R;Raduenz, E;Beitz, AJ;Gupta, K;
2016
27687125
September 30th, 2016
United States
Vascular Biology Center, Division of Hematology, Oncology &Transplantation, Department of Medicine, University of Minnesota, 14-100 PWB, 516 Delaware ST SE, Minneapolis, MN 55455, USA
Macrophages form functional vascular mimicry channels in vivo
Scientific Reports
Barnett, FH;Rosenfeld, M;Wood, M;Kiosses, WB;Usui, Y;Marchetti, V;Aguilar, E;Friedlander, M;
2016
27834402
November 11th, 2016
United States
Department of Cell and Molecular Biology, The Scripps Research Institute, 10550 N. Torrey Pines Rd, La Jolla, CA 92037, USA
miR-182 Modulates Myocardial Hypertrophic Response Induced by Angiogenesis in Heart
Scientific Reports
Li, N;Hwangbo, C;Jaba, IM;Zhang, J;Papangeli, I;Han, J;Mikush, N;Larriv̩e, B;Eichmann, A;Chun, HJ;Young, LH;Tirziu, D;
2016
26888314
February 18th, 2016
United States
Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, 06520, USA
Sensory hypo-excitability in a rat model of fetal development in Fragile X Syndrome
Scientific Reports
Berzhanskaya, J;Phillips, MA;Shen, J;Colonnese, MT;
2016
27465362
July 28th, 2016
United States
College of Mechanical and Electronic Engineering, Northwest A&F University, Washington, DC 20052, United States
The astrocytic transporter SLC7A10 (Asc-1) mediates glycinergic inhibition of spinal cord motor neurons
Scientific Reports
Ehmsen, JT;Liu, Y;Wang, Y;Paladugu, N;Johnson, AE;Rothstein, JD;du Lac, S;Mattson, MP;H̦ke, A;
2016
27759100
October 19th, 2016
United States
Department of Neurology, Johns Hopkins School of Medicine, 855 N. Wolfe Street, Baltimore, Maryland, 21205, USA
Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis
Scientific Reports
O'Conor, CJ;Ramalingam, S;Zelenski, NA;Benefield, HC;Rigo, I;Little, D;Wu, CL;Chen, D;Liedtke, W;McNulty, AL;Guilak, F;
2016
27388701
July 8th, 2016
United States
Department of Orthopaedic Surgery, Washington University in St. Louis, Missouri, 63110, USA
Magnetic Resonance Spectroscopy discriminates the response to microglial stimulation of wild type and Alzheimer''s disease models
Scientific Reports
Pardon, MC;Yanez Lopez, M;Yuchun, D;MarjaÂãska, M;Prior, M;Brignell, C;Parhizkar, S;Agostini, A;Bai, L;Auer, DP;Faas, HM;
2016
26813748
January 27th, 2016
United Kingdom
Neuroscience, School of Life Sciences, University of Nottingham United Kingdom
Microfluidic squeezing for intracellular antigen loading in polyclonal B-cells as cellular vaccines
Scientific Reports
Szeto, GL;Van Egeren, D;Worku, H;Sharei, A;Alejandro, B;Park, C;Frew, K;Brefo, M;Mao, S;Heimann, M;Langer, R;Jensen, K;Irvine, DJ;
2015
25999171
May 22nd, 2015
United States
1] Department of Materials Science &Engineering, MIT [2] Department of Biological Engineering, MIT [3] David. H. Koch Institute for Integrative Cancer Research, MIT [4] The Ragon Institute of Harvard, MIT, and MGH
Crumbs3 is essential for proper epithelial development and viability
Molelcular and Cellular Biology
Whiteman, EL;Fan, S;Harder, JL;Walton, KD;Liu, CJ;Soofi, A;Fogg, VC;Hershenson, MB;Dressler, GR;Deutsch, GH;Gumucio, DL;Margolis, B;
2014
24164893
January 1st, 2014
United States
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA
Enhanced Cognition and Hypoglutamatergic Signaling in a Growth Hormone Receptor Knockout Mouse Model of Successful Aging
Journals of Gerontology
Hascup, KN;Lynn, MK;Fitzgerald, PJ;Randall, S;Kopchick, JJ;Boger, HA;Bartke, A;Hascup, ER;
2016
27208894
May 21st, 2016
United States
Department of Neurology, Center for Alzheimer's Disease and Related Disorders, Southern Illinois University School of Medicine, Springfield. Department of Pharmacology, Southern Illinois University School of Medicine, Springfield
Primary cancer cell culture: mammary-optimized vs conditional reprogramming
Endocrine Related Cancer
Alamri, AM;Kang, K;Groeneveld, S;Wang, W;Zhong, X;Kallakury, B;Hennighausen, L;Liu, X;Furth, PA;
2016
27267121
July 1st, 2016
United States
Department of OncologyLombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA Department of MedicineLombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA
Microglial p38ë± MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aë_)
Journal of Neuroinflammation
Bachstetter, AD;Xing, B;de Almeida, L;Dimayuga, ER;Watterson, DM;Van Eldik, LJ;
2011
21733175
July 6th, 2011
United States
Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA
The p38alpha mitogen-activated protein kinase limits the CNS proinflammatory cytokine response to systemic lipopolysaccharide, potentially through an IL-10 dependent mechanism
Journal of Neuroinflammation
Bachstetter, AD;Xing, B;Van Eldik, LJ;
2014
25297465
October 10th, 2014
United States
Sanders-Brown Center on Aging, University of Kentucky, 800 S, Limestone Street, Lexington 40536, KY, USA
Age exacerbates the CCR2/5-mediated neuroinflammatory response to traumatic brain injury
Journal of Neuroinflammation
Morganti, JM;Riparip, LK;Chou, A;Liu, S;Gupta, N;Rosi, S;
2016
27090212
April 18th, 2016
United States
Brain and Spinal Injury Center, University of California, 1001 Potrero Ave, Bldg. 1, Room 101, San Francisco, CA, 94110, USA
Deficiency of complement receptors CR2/CR1 in Cr2‰ÂÈ/‰ÂÈ mice reduces the extent of secondary brain damage after closed head injury
Journal of Neuroinflammation
Neher, MD;Rich, MC;Keene, CN;Weckbach, S;Bolden, AL;Losacco, JT;Patane, J;Flierl, MA;Kulik, L;Holers, VM;Stahel, PF;
2014
24885042
May 24th, 2014
United States
Department of Orthopedic Surgery, Denver Health Medical Center, University of Colorado School of Medicine, 777 Bannock Street, Denver CO 80204, USA
Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease
Neurobiology of Aging
Rosa, E;Mahendram, S;Ke, YD;Ittner, LM;Ginsberg, SD;Fahnestock, M;
2016
27676333
August 31st, 2016
Canada
Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada
Accelerated protein damage in brains of PIMT+/- mice; a possible model for the variability of cognitive decline in human aging
Neurobiology of Aging
Qin, Z;Dimitrijevic, A;Aswad, DW;
2015
25465735
February 1st, 2015
United States
Department of Molecular Biology & Biochemistry, University of California, Irvine, Irvine, CA, USA
CB䉉 receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease
Molecular Medicine
Koppel, J;Vingtdeux, V;Marambaud, P;d'Abramo, C;Jimenez, H;Stauber, M;Friedman, R;Davies, P;
2013
24408112
November 8th, 2013
United States
Litwin-Zucker Research Center, Feinstein Institute for Medical Research, North-Shore Long Island Jewish Health System, Manhasset, New York, United States of America
Transcriptional dysregulation causes altered modulation of inhibition by haloperidol
Neuropharmacology
Brady, LJ;Bartley, AF;Li, Q;McMeekin, LJ;Hablitz, JJ;Cowell, RM;Dobrunz, LE;
2016
27480797
December 1st, 2016
United States
Department of Neurobiology and Evelyn F. McKnight Brain Institute, University of Alabama at Birmingham, 1825 University Blvd., Birmingham, AL, USA; Civitan International Research Center, University of Alabama at Birmingham, 1719 6th Ave. S., Birmingham, AL, USA
In vitro gamma oscillations following partial and complete ablation of ë« subunit-containing GABAA receptors from parvalbumin interneurons
Neuropharmacology
Ferando, I;Mody, I;
2015
25261782
January 1st, 2015
United States
Departments of Neurology, The David Geffen School of Medicine, University of California, Los Angeles, CA, USA; Departments of Physiology, The David Geffen School of Medicine, University of California, Los Angeles, CA, USA
Monitoring cholinergic activity during attentional performance in mice heterozygous for the choline transporter: a model of cholinergic capacity limits
Neuropharmacology
Paolone, G;Mallory, CS;Koshy Cherian, A;Miller, TR;Blakely, RD;Sarter, M;
2013
23958450
December 1st, 2013
United States
Department of Psychology & Neuroscience Program, University of Michigan, Ann Arbor, MI 48103, USA
Attenuated p53 activation in tumour-associated stromal cells accompanies decreased sensitivity to etoposide and vincristine
British Journal of Cancer
Dudley, AC;Shih, SC;Cliffe, AR;Hida, K;Klagsbrun, M;
2008
18594537
July 1st, 2008
United States
Vascular Biology Program, Department of Surgery, Children's Hospital and Harvard Medical School, Boston, MA 02115, USA
The ability of an attaching and effacing pathogen to trigger localized actin assembly contributes to virulence by promoting mucosal attachment
Cellular Microbiology
Mallick, EM;Garber, JJ;Vanguri, VK;Balasubramanian, S;Blood, T;Clark, S;Vingadassalom, D;Louissaint, C;McCormick, B;Snapper, SB;Leong, JM;
2014
24780054
September 1st, 2014
United States
Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA
Fatty Acid-Binding Protein 5 Facilitates the Blood-Brain Barrier Transport of Docosahexaenoic Acid
Molecular Pharmaceutics
Pan, Y;Scanlon, MJ;Owada, Y;Yamamoto, Y;Porter, CJ;Nicolazzo, JA;
2015
26455443
December 1st, 2015
Australia
Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences,Monash University, 399 Royal Parade, Parkville, Victoria 3052, Australia
KISS1R signals independently of Gë±q/11 and triggers LH secretion via the ë_-arrestin pathway in the male mouse
Endocrinology
Ahow, M;Min, L;Pampillo, M;Nash, C;Wen, J;Soltis, K;Carroll, RS;Glidewell-Kenney, CA;Mellon, PL;Bhattacharya, M;Tobet, SA;Kaiser, UB;Babwah, AV;
2014
25147978
November 1st, 2014
Canada
Children's Health Research Institute, Victoria Research Laboratories, A4‰ÛÒ140, 800 Commissioners Road East, London, Ontario, Canada N6C 2V5.
Reduced melanocortin production causes sexual dysfunction in male mice with POMC neuronal insulin and leptin insensitivity
Endocrinology
Faulkner, LD;Dowling, AR;Stuart, RC;Nillni, EA;Hill, JW;
2015
25590244
April 1st, 2015
United States
Department of Physiology and Pharmacology (L.D.F., A.R.D., J.W.H.), College of Medicine, The University of Toledo, Toledo, Ohio 43614-2598; and Division of Endocrinology (R.C.S., E.A.N.), Department of Medicine, The Warren Alpert Medical School of Brown University, Providence, Rhode Island 02912-9107
Delayed puberty but normal fertility in mice with selective deletion of insulin receptors from Kiss1 cells
Endocrinology
Qiu, X;Dowling, AR;Marino, JS;Faulkner, LD;Bryant, B;BrÌ_ning, JC;Elias, CF;Hill, JW;
2013
23392256
March 1st, 2013
United States
Center for Diabetes and Endocrine Research, University of Toledo College of Medicine, Toledo, OH 43614, USA
Mechanisms of amylin/leptin synergy in rodent models
Endocrinology
Turek, VF;Trevaskis, JL;Levin, BE;Dunn-Meynell, AA;Irani, B;Gu, G;Wittmer, C;Griffin, PS;Vu, C;Parkes, DG;Roth, JD;
2010
19875640
January 1st, 2010
United States
Amylin Pharmaceuticals, Inc., 9360 Towne Centre Drive, San Diego, California 92121, USA
Regulation of brain PPARgamma2 contributes to ketogenic diet anti-seizure efficacy
Experimental Neurology
Simeone, TA;Matthews, SA;Samson, KK;Simeone, KA;
2017
27527983
January 1st, 2017
United States
Creighton University, School of Medicine, Department of Pharmacology, Omaha, NE 68174, USA
Preservation of neuromuscular function in symptomatic SOD1-G93A mice by peripheral infusion of methylene blue
Experimental Neurology
Talbot, JD;Barrett, JN;Nonner, D;Zhang, Z;Wicomb, K;Barrett, EF;
2016
27567739
November 1st, 2016
United States
Department of Physiology and Biophysics, University of Miami Miller School of Medicine, P.O. Box 016430, Miami, FL 33101, USA; Neuroscience Program, University of Miami Miller School of Medicine, Miami, FL, USA 33101
Desert hedgehog is a mediator of demyelination in compression neuropathies
Experimental Neurology
Jung, J;Frump, D;Su, J;Wang, W;Mozaffar, T;Gupta, R;
2015
25936873
September 1st, 2015
United States
Department of Orthopaedic Surgery, University of California, Irvine, CA 92697, USA; Department of Biomedical Engineering, University of California, Irvine, CA 92697, USA; Department of Anatomy and Neurobiology, University of California, Irvine, CA 92697, USA
BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle
American Journal of Pathology
Kennedy, TL;Swiderski, K;Murphy, KT;Gehrig, SM;Curl, CL;Chandramouli, C;Febbraio, MA;Delbridge, LM;Koopman, R;Lynch, GS;
2016
27750047
December 1st, 2016
Australia
Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, Melbourne, Victoria
The PPARë_ agonist efatutazone increases the spectrum of well-differentiated mammary cancer subtypes initiated by loss of full-length BRCA1 in association with TP53 haploinsufficiency
American Journal of Pathology
Nakles, RE;Kallakury, BV;Furth, PA;
2013
23664366
June 1st, 2013
United States
Department of Oncology, Georgetown University, Washington, District of Columbia 20057, USA
The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity
Journal of Biological Chemisrty
Clement, CC;Becerra, A;Yin, L;Zolla, V;Huang, L;Merlin, S;Follenzi, A;Shaffer, SA;Stern, LJ;Santambrogio, L;
2016
26740625
March 11th, 2016
United States
From the Departments of Pathology and Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York 10461
Hepatic Insulin Resistance Following Chronic Activation of the CREB Coactivator CRTC2
Journal of Biological Chemisrty
Hogan, MF;Ravnskjaer, K;Matsumura, S;Huising, MO;Hull, RL;Kahn, SE;Montminy, M;
2015
26342077
October 23rd, 2015
United States
From the Peptide Biology Laboratories, Salk Institute for Biological Studies, La Jolla, California 92037
Central Mechanisms Mediating Thrombospondin-4-induced Pain States
Journal of Biological Chemisrty
Park, J;Yu, YP;Zhou, CY;Li, KW;Wang, D;Chang, E;Kim, DS;Vo, B;Zhang, X;Gong, N;Sharp, K;Steward, O;Vitko, I;Perez-Reyes, E;Eroglu, C;Barres, B;Zaucke, F;Feng, G;Luo, ZD;
2016
27129212
June 17th, 2016
United States
From the Department of Pharmacology and Department of Anesthesiology and Perioperative Care, University of California, Irvine, California 92697, Reeve-Irvine Research Center, University of California, Irvine, School of Medicine, Irvine, California 92697
Purinergic control of hippocampal circuit hyperexcitability in Dravet syndrome
Epilepsia
Gu, F;Hazra, A;Aulakh, A;Â_iburkus, J;
2014
24417577
February 1st, 2014
United States
Department of Biology and Biochemistry, University of Houston, Houston, Texas, U.S.A
In vivo ketogenic diet treatment attenuates pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices from epileptic Kv 1.1ë± knockout mice
Epilepsia
Simeone, TA;Samson, KK;Matthews, SA;Simeone, KA;
2014
24702645
May 1st, 2014
United States
Department of Pharmacology, School of Medicine, Creighton University, Omaha, Nebraska, U.S.A
Optogenetic stimulation of cholinergic brainstem neurons during focal limbic seizures: Effects on cortical physiology
Epilepsia
Furman, M;Zhan, Q;McCafferty, C;Lerner, BA;Motelow, JE;Meng, J;Ma, C;Buchanan, GF;Witten, IB;Deisseroth, K;Cardin, JA;Blumenfeld, H;
2015
26530287
December 1st, 2015
United States
Department of Neurology, Yale University School of Medicine, New Haven, Connecticut, U.S.A
Ketogenic diet treatment increases longevity in Kcna1-null mice, a model of sudden unexpected death in epilepsy
Epilepsia
Simeone, KA;Matthews, SA;Rho, JM;Simeone, TA;
2016
27346881
August 1st, 2016
United States
Department of Pharmacology, Creighton University School of Medicine, Omaha, Nebraska, U.S.A
Ketogenic diet treatment abolishes seizure periodicity and improves diurnal rhythmicity in epileptic Kcna1-null mice
Epilepsia
Fenoglio-Simeone, KA;Wilke, JC;Milligan, HL;Allen, CN;Rho, JM;Maganti, RK;
2009
19490051
September 1st, 2009
United States
Barrow Neurological Institute and St. Joseph's Medical Center, Neurology Research, Phoenix, Arizona 85013, USA
Research tool: Validation of floxed ë±7 nicotinic acetylcholine receptor conditional knockout mice using in vitro and in vivo approaches
Journal of Physiology (London)
Hernandez, CM;Cortez, I;Gu, Z;ColÃŒ_n-SÃŒÃez, JO;Lamb, PW;Wakamiya, M;Yakel, JL;Dineley, KT;
2014
24879866
August 1st, 2014
United States
Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch at Galveston (UTMB), Galveston, TX, USA Department of Neurology, UTMB, Galveston, TX, USA Rodent In Vivo Assessment Core, UTMB, Galveston, TX, USA Center for Addiction Research, UTMB, Galveston, TX, USA
Fluorescence recovery after photobleaching reveals regulation and distribution of connexin36 gap junction coupling within mouse islets of Langerhans
Journal of Physiology (London)
Farnsworth, NL;Hemmati, A;Pozzoli, M;Benninger, RK;
2014
25172942
October 15th, 2014
United States
Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, CO, USA Department of Bioengineering, University of Colorado, Aurora, CO, USA
Utrophin regulates modal gating of mechanosensitive ion channels in dystrophic skeletal muscle
Journal of Physiology (London)
Tan, N;Lansman, JB;
2014
24879867
August 1st, 2014
United States
Department of Cellular and Molecular Pharmacology, School of Medicine, University of California, San Francisco, San Francisco, CA, 94143-0450, USA
CLC-3 chloride channels moderate long-term potentiation at Schaffer collateral-CA1 synapses
Journal of Physiology (London)
Farmer, LM;Le, BN;Nelson, DJ;
2013
23165767
February 15th, 2013
United States
Department of Neurobiology, Pharmacology and Physiology, The University of Chicago, Chicago, IL 60637, USA
Physiological and morphological properties of Dbx1-derived respiratory neurons in the pre-Botzinger complex of neonatal mice
Journal of Physiology (London)
Picardo, MC;Weragalaarachchi, KT;Akins, VT;Del Negro, CA;
2013
23459755
May 15th, 2013
United States
Department of Applied Science, McGlothlin-Street Hall, Room 318, The College of William & Mary, Williamsburg, VA 23187-8795, USA
Is connexin36 critical for GABAergic hypersynchronization in the hippocampus?
Journal of Physiology (London)
Beaumont, M;Maccaferri, G;
2011
21300748
April 1st, 2011
United States
Northwestern University Interdepartmental Neuroscience Program, Department of Physiology, Feinberg School of Medicine, 303 E Chicago Ave, Tarry Blg Rm 5-707, Chicago, IL 60611, USA
Automated cell-specific laser detection and ablation of neural circuits in neonatal brain tissue
Journal of Physiology (London)
Wang, X;Hayes, JA;Picardo, MC;Del Negro, CA;
2013
23440965
May 15th, 2013
United States
Department of Applied Science, McGlothlin-Street Hall, Room 318, The College of William & Mary, Williamsburg, VA 23187-8795, USA
T-bet is essential for Th1-mediated, but not Th17-mediated, CNS autoimmune disease
European Journal of Immunology
O'Connor, RA;Cambrook, H;Huettner, K;Anderton, SM;
2013
23878019
November 1st, 2013
United Kingdom
Medical Research Council Centre for Inflammation Research, Centre for Multiple Sclerosis Research and Centre for Immunity Infection and Evolution, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK
CD40 engagement of CD4+ CD40+ T cells in a neo-self antigen disease model ablates CTLA-4 expression and indirectly impacts tolerance
European Journal of Immunology
Carter, J;Vaitaitis, GM;Waid, DM;Wagner, DH;
2012
22105491
February 1st, 2012
United States
The Webb-Waring Center, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
Lineage tracking of mesenchymal and endothelial progenitors in BMP-induced bone formation
Bone
Kolind, M;Bobyn, JD;Matthews, BG;Mikulec, K;Aiken, A;Little, DG;Kalajzic, I;Schindeler, A;
2015
26141839
December 1st, 2015
Australia
Centre for Children's Bone Health, The Children's Hospital at Westmead, Westmead, NSW, Australia; Discipline of Paediatrics and Child Health, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia
Activity-dependent neuroprotective protein (ADNP) exhibits striking sexual dichotomy impacting on autistic and Alzheimer's pathologies
Translational Psychiatry
Malishkevich, A;Amram, N;Hacohen-Kleiman, G;Magen, I;Giladi, E;Gozes, I;
2015
25646590
February 3rd, 2015
Israel
The Lily and Avraham Gildor Chair for Investigation of Growth Factors; The Elton Laboratory for Molecular Neuroendocrinology, Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Sagol School of Neuroscience and Adams Super Center for Brain Studies, Tel Aviv University, Tel Aviv, Israel
The activin A antagonist follistatin inhibits cystic fibrosis-like lung inflammation and pathology
Immunology and Cell Biology
Hardy, CL;King, SJ;Mifsud, NA;Hedger, MP;Phillips, DJ;Mackay, F;de Kretser, DM;Wilson, JW;Rolland, JM;O'Hehir, RE;
2015
25753271
July 1st, 2015
United States
1] Department of Allergy, Immunology & Respiratory Medicine, Central Clinical School, Monash University, Melbourne, Victoria, Australia [2] Department of Immunology, Central Clinical School, Monash University, Melbourne, Victoria, Australia
Mutation-independent rescue of a novel mouse model of Retinitis Pigmentosa
Gene Therapy
Greenwald, DL;Cashman, SM;Kumar-Singh, R;
2013
22809998
April 1st, 2013
United States
Department of Ophthalmology, Tufts University School of Medicine, Boston, MA 02111, USA
Ovarian cycle-linked plasticity of ë«-GABAA receptor subunits in hippocampal interneurons affects ë_ oscillations in vivo
Frontiers in Cellular Neuroscience
Barth, AM;Ferando, I;Mody, I;
2014
25157218
August 26th, 2014
United States
Department of Neurology, The David Geffen School of Medicine, University of California at Los Angeles Los Angeles, CA, USA ; Department of Physiology, The David Geffen School of Medicine, University of California at Los Angeles Los Angeles, CA, USA
Regulation of ethanol intake under chronic mild stress: roles of dopamine receptors and transporters
Frontiers in Behavioral Neuroscience
Delis, F;Rombola, C;Bellezza, R;Rosko, L;Grandy, DK;Volkow, ND;Thanos, PK;
2015
26029066
June 1st, 2015
United States
Department of Psychology, State University of New York at Stony Brook Stony Brook, NY, USA
TIR Domain-Containing Adapter-Inducing Beta Interferon (TRIF) Mediates Immunological Memory against Bacterial Pathogens
Infection and Immunity
Kanagavelu, S;Flores, C;Termini, JM;Romero, L;Riveron, R;Ruiz, J;Arditi, M;Schesser, K;Fukata, M;
2015
26351279
November 1st, 2015
United States
Division of Gastroenterology, Department of Medicine, Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA
SOCS-3 Regulates Alveolar Bone Loss in Experimental Periodontitis
Journal of Dental Research
Papathanasiou, E;Kantarci, A;Konstantinidis, A;Gao, H;Van Dyke, TE;
2016
27126447
August 1st, 2016
United States
Department of Applied Oral Sciences, Center for Periodontology, Forsyth Institute, Cambridge, MA, USA
Skeletal muscle glucose uptake during treadmill exercise in neuronal nitric oxide synthase-ë_ knockout mice
American Journal of Physiology Endocrinology and Metabolism
Hong, YH;Yang, C;Betik, AC;Lee-Young, RS;McConell, GK;
2016
27006199
May 15th, 2016
Malaysia
College of Health and Biomedicine, Victoria University, Melbourne, Victoria, Australia; Clinical Exercise Science Program, Institute of Sport, Exercise and Active Living, Victoria University, Melbourne, Victoria, Australia; Department of Physiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia; and
The absence of 25-hydroxyvitamin D3-1ë±-hydroxylase potentiates the suppression of EAE in mice by ultraviolet light
Journal of Steroid Biochemistry and Molecular Biology
Wang, Y;Marling, SJ;Martino, VM;Prahl, JM;Deluca, HF;
2016
27108944
October 1st, 2016
United States
Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706-1544, United States
Fibroblast-specific expression of AC6 enhances beta-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis
American Journal of Physiology Lung Cellular and Molecular Physiology
Liu, X;Li, F;Sun, SQ;Thangavel, M;Kaminsky, J;Balazs, L;Ostrom, RS;
2010
20348281
June 1st, 2010
United States
Department of Pharmacology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
Periostin promotes fibrosis and predicts progression in patients with idiopathic pulmonary fibrosis
American Journal of Physiology Lung Cellular and Molecular Physiology
Naik, PK;Bozyk, PD;Bentley, JK;Popova, AP;Birch, CM;Wilke, CA;Fry, CD;White, ES;Sisson, TH;Tayob, N;Carnemolla, B;Orecchia, P;Flaherty, KR;Hershenson, MB;Murray, S;Martinez, FJ;Moore, BB;, ;
2012
23043074
December 15th, 2012
United States
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Toll-like receptor 2 mediates mesenchymal stem cell-associated myocardial recovery and VEGF production following acute ischemia-reperfusion injury
American Journal of Physiology Heart and Circulatory Physiology
Abarbanell, AM;Wang, Y;Herrmann, JL;Weil, BR;Poynter, JA;Manukyan, MC;Meldrum, DR;
2010
20173040
May 1st, 2010
United States
Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
ApoE deficiency exacerbates the development and sustainment of a semi-chronic K/BxN serum transfer-induced arthritis model
Journal of Translational Medicine
Archer, AM;Saber, R;Rose, S;Shaffer, A;Misharin, AV;Tsai, F;Haines Iii, GK;Dominguez, S;Eren, M;Vaughan, DE;Cuda, CM;Perlman, H;
2016
27287704
June 10th, 2016
United States
Division of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, 240 East Huron Street, McGaw M338, Chicago, IL, 60611, USA
EP2 and EP4 receptors mediate PGE2 induced relaxation in murine colonic circular muscle: pharmacological characterization
Pharmacology Research
Martinez-Cutillas, M;Ma̱̩, N;Gallego, D;Jimenez, M;Martin, MT;
2014
25461458
December 1st, 2014
Spain
Department of Cell Biology, Physiology and Immunology, Universitat AutÃŒ_noma de Barcelona, Barcelona, Spain; Centro de InvestigaciÃŒ_n BiomÌ©dica en Red de Enfermedades HepÃŒÃticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Barcelona, Spain
Males are from Mars, and females are from Venus: sex-specific fetal brain gene expression signatures in a mouse model of maternal diet-induced obesity
American Journal of Obsterics and Gynecology
Edlow, AG;Guedj, F;Pennings, JL;Sverdlov, D;Neri, C;Bianchi, DW;
2016
26945603
May 1st, 2016
United States
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Tufts Medical Center, Boston, MA; Mother Infant Research Institute, Tufts Medical Center, Boston, MA
Network of brain protein level changes in glutaminase deficient fetal mice
Journal of Proteomics
Bae, N;Wang, Y;Li, L;Rayport, S;Lubec, G;
2013
23376484
March 27th, 2013
Austria
Department of Pediatrics, Medical University of Vienna, WÌ_hringer GÌ_rtel 18, 1090 Vienna, Austria
Neurological Dysfunction in Early Maturity of a Model for Niemann-Pick C1 Carrier Status
Neurotherapeutics
Hung, YH;Walterfang, M;Churilov, L;Bray, L;Jacobson, LH;Barnham, KJ;Jones, NC;O'Brien, TJ;Velakoulis, D;Bush, AI;
2016
26942423
July 1st, 2016
Australia
Oxidation Biology Unit, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, 3010, Australia
Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity
Journal of Pharmacology and Expreimental Therapeutics
Longo, KA;Govek, EK;Nolan, A;McDonagh, T;Charoenthongtrakul, S;Giuliana, DJ;Morgan, K;Hixon, J;Zhou, C;Kelder, B;Kopchick, JJ;Saunders, JO;Navia, MA;Curtis, R;DiStefano, PS;Geddes, BJ;
2011
21775475
October 1st, 2011
United States
Elixir Pharmaceuticals, Inc, Cambridge, Massachusetts, USA
Enhancing eNOS activity with simultaneous inhibition of IKKë_ restores vascular function in Ins2(Akita+/-) type-1 diabetic mice
Laboratory Investigation
Krishnan, M;Janardhanan, P;Roman, L;Reddick, RL;Natarajan, M;van Haperen, R;Habib, SL;de Crom, R;Mohan, S;
2015
26214584
October 1st, 2015
United States
Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
Quantitative assessment of pancreatic cancer precursor lesions in IHC-stained tissue with a tissue image analysis platform
Laboratory Investigation
Aeffner, F;Martin, NT;Peljto, M;Black, JC;Major, JK;Jangani, M;Ports, MO;Krueger, JS;Young, GD;
2016
27775692
December 1st, 2016
United States
Flagship Biosciences Inc., Westminster, CO, USA
Mice lacking sialyltransferase ST3Gal-II develop late onset obesity and insulin resistance
Glycobiology
Lopez, PH;Aja, S;Aoki, K;Seldin, MM;Lei, X;Ronnett, GV;Wong, GW;Schnaar, RL;
2016
27683310
September 28th, 2016
United States
Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205 USA Departments of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205 USA
c-Met signalling is required for efficient postnatal thymic regeneration and repair
Immunology
Song, Y;Su, M;Panchatsharam, P;Rood, D;Lai, L;
2015
25074726
February 1st, 2015
United States
Department of Allied Health Sciences, University of Connecticut, Storrs, CT, USA
Nervous-tissue-specific elimination of microtubule-actin crosslinking factor 1a results in multiple developmental defects in the mouse brain
Molecular and Cellular Neuroscience
Goryunov, D;He, CZ;Lin, CS;Leung, CL;Liem, RK;
2010
20170731
May 1st, 2010
United States
Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, NY, NY 10032, USA
Cooperative regulation of neurotransmitter release by Rab3a and synapsin II
Molecular and Cellular Neuroscience
Coleman, WL;Bykhovskaia, M;
2010
20338242
June 1st, 2010
United States
Department of Biological Sciences, Lehigh University, Bethlehem, PA, USA
Tissue inducible Lifeact expression allows visualization of actin dynamics in vivo and ex vivo
European Journal of Cell Biology
Schachtner, H;Li, A;Stevenson, D;Calaminus, SD;Thomas, SG;Watson, SP;Sixt, M;Wedlich-Soldner, R;Strathdee, D;Machesky, LM;
2012
22658956
October 15th, 2012
United Kingdom
The Beatson Institute for Cancer Research, Garscube Estate, Bearsden, Glasgow, United Kingdom
Mis-expression of the BK K(+) channel disrupts suprachiasmatic nucleus circuit rhythmicity and alters clock-controlled behavior
American Journal of Physiology, Cell Physiology
Montgomery, JR;Whitt, JP;Wright, BN;Lai, MH;Meredith, AL;
2013
23174562
February 15th, 2013
United States
Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Delayed in vitro development of Up states but normal network plasticity in Fragile X circuits
European Journal of Neuroscience
Motanis, H;Buonomano, D;
2015
26138886
September 1st, 2015
United States
Departments of Neurobiology and Psychology, Integrative Center for Learning and Memory, University of California, 695 Young Drive, Gonda, Los Angeles, CA, 90095, USA
Dopamine increases NMDA-stimulated calcium flux in striatopallidal neurons through a matrix metalloproteinase-dependent mechanism
European Journal of Neuroscience
Li, Y;Partridge, J;Berger, C;Sepulveda-Rodriguez, A;Vicini, S;Conant, K;
2016
26660285
January 1st, 2016
United States
Departments of Neuroscience and Pharmacology, Georgetown University, 3970 Reservoir Road, Washington, DC, USA
Intact brown adipose tissue thermogenesis is required for restorative sleep responses after sleep loss
European Journal of Neuroscience
Szentirmai, Ìä;KapÃŒÃs, L;
2014
24372950
March 1st, 2014
United States
Washington, Wyoming, Alaska, Montana and Idaho (WWAMI) Medical Education Program, PO Box 1495, Spokane, WA 99210-1495, USA; Department of Integrative Physiology and Neuroscience, Pullman, WA, USA; Sleep and Performance Research Center, Washington State University, Spokane, WA, USA
Impaired wake-promoting mechanisms in ghrelin receptor-deficient mice
European Journal of Neuroscience
Esposito, M;Pellinen, J;KapÃŒÃs, L;Szentirmai, Ìä;
2012
22211783
January 1st, 2012
United States
Washington, Wyoming, Alaska, Montana and Idaho (WWAMI) Medical Education Program, Washington State University, PO Box 1495, Spokane, WA 99210-1495, USA
5'-Ectonucleotidase-knockout mice lack non-REM sleep responses to sleep deprivation
European Journal of Neuroscience
Zielinski, MR;Taishi, P;Clinton, JM;Krueger, JM;
2012
22540145
June 1st, 2012
United States
Sleep and Performance Research Center, Programs in Neuroscience, WWAMI Medical Education Program, Washington State University, Spokane, WA 99210-1495, USA
RPGR-associated retinal degeneration in human X-linked RP and a murine model
Investigative Ophthalmology and Visual Science
Huang, WC;Wright, AF;Roman, AJ;Cideciyan, AV;Manson, FD;Gewaily, DY;Schwartz, SB;Sadigh, S;Limberis, MP;Bell, P;Wilson, JM;Swaroop, A;Jacobson, SG;
2012
22807293
August 15th, 2012
United States
Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
L450W and Q455K Col8a2 knock-in mouse models of Fuchs endothelial corneal dystrophy show distinct phenotypes and evidence for altered autophagy
Investigative Ophthalmology and Visual Science
Meng, H;Matthaei, M;Ramanan, N;Grebe, R;Chakravarti, S;Speck, CL;Kimos, M;Vij, N;Eberhart, CG;Jun, AS;
2013
23422828
March 28th, 2013
United States
Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
Altered Refractive Development in Mice With Reduced Levels of Retinal Dopamine
Investigative Ophthalmology and Visual Science
Bergen, MA;Park, HN;Chakraborty, R;Landis, EG;Sidhu, C;He, L;Iuvone, PM;Pardue, MT;
2016
27750284
August 1st, 2016
United States
Center for Visual and Neurocognitive Rehabilitation, Atlanta VA Medical Center, Decatur, Georgia, United States 2Biology, Emory University, Atlanta, Georgia, United States
Isoaspartyl protein damage and repair in mouse retina
Investigative Ophthalmology and Visual Science
Qin, Z;Yang, J;Klassen, HJ;Aswad, DW;
2014
24550364
March 13th, 2014
United States
Department of Molecular Biology and Biochemistry, University of California, Irvine, California
Reduced ocular blood flow as an early indicator of diabetic retinopathy in a mouse model of diabetes
Investigative Ophthalmology and Visual Science
Muir, ER;RenterÌ_a, RC;Duong, TQ;
2012
22915034
September 21st, 2012
United States
Research Imaging Institute, University of Texas Health Science Center, San Antonio, Texas 78229, USA
The D-isoAsp-25 variant of histone H2B is highly enriched in active chromatin: potential role in the regulation of gene expression?
Amino Acids
Qin, Z;Zhu, JX;Aswad, DW;
2016
26666674
February 1st, 2016
China
Department of Molecular Biology and Biochemistry, University of California, 3205 McGaugh Hall, Irvine, CA, 92697-3900, USA
WDR72 models of structure and function: a stage-specific regulator of enamel mineralization
Matrix Biology
Katsura, KA;Horst, JA;Chandra, D;Le, TQ;Nakano, Y;Zhang, Y;Horst, OV;Zhu, L;Le, MH;DenBesten, PK;
2014
25008349
September 1st, 2014
United States
Department of Oral and Craniofacial Sciences, School of Dentistry, University of California, San Francisco, 513 Parnassus Ave., San Francisco, CA 94143-0422, USA
p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas
Developmental Biology
Hendley, AM;Provost, E;Bailey, JM;Wang, YJ;Cleveland, MH;Blake, D;Bittman, RW;Roeser, JC;Maitra, A;Reynolds, AB;Leach, SD;
2015
25523391
March 1st, 2015
United States
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; The McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
A quantitative method for defining high-arched palate using the Tcof1(+/-) mutant mouse as a model
Developmental Biology
Conley, ZR;Hague, M;Kurosaka, H;Dixon, J;Dixon, MJ;Trainor, PA;
2016
26772999
July 15th, 2016
United States
The Stowers Institute for Medical Research, Kansas City, MO, United States; Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS, United States
Integrin-ë±5ë_1 is not required for mural cell functions during development of blood vessels but is required for lymphatic-blood vessel separation and lymphovenous valve formation
Developmental Biology
Turner, CJ;Badu-Nkansah, K;Crowley, D;van der Flier, A;Hynes, RO;
2014
24858485
August 15th, 2014
United States
Howard Hughes Medical Institute, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice
Toxicology and Applied Pharmacology
Harrill, JA;Hukkanen, RR;Lawson, M;Martin, G;Gilger, B;Soldatow, V;Lecluyse, EL;Budinsky, RA;Rowlands, JC;Thomas, RS;
2013
23859880
October 15th, 2013
United States
The Hamner Institute for Health Sciences, Institute for Chemical Safety Sciences, RTP, NC 27709, USA
MKP1-dependent PTH modulation of bone matrix mineralization in female mice is osteoblast maturation stage specific and involves P-ERK and P-p38 MAPKs
Journal of Endocrinology
Mahalingam, CD;Sampathi, BR;Sharma, S;Datta, T;Das, V;Abou-Samra, AB;Datta, NS;
2013
23197743
March 1st, 2013
United States
Division of Endocrinology, Department of Internal Medicine, Wayne State University School of Medicine, 1107 Elliman Clinical Research Building, 421 East Canfield Avenue, Detroit, Michigan 48201, USA
Mitogen-activated protein kinase phosphatase 1 regulates bone mass, osteoblast gene expression, and responsiveness to parathyroid hormone
Journal of Endocrinology
Mahalingam, CD;Datta, T;Patil, RV;Kreider, J;Bonfil, RD;Kirkwood, KL;Goldstein, SA;Abou-Samra, AB;Datta, NS;
2011
21852324
November 1st, 2011
United States
Division of Endocrinology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
Blood-brain barrier impairment in an animal model of MPS III B
PLOS ONE
Garbuzova-Davis, S;Louis, MK;Haller, EM;Derasari, HM;Rawls, AE;Sanberg, PR;
2011
21408219
March 7th, 2011
United States
College of Medicine, Center of Excellence for Aging & Brain Repair, University of South Florida, Tampa, Florida, United States of America
Neonatal periostin knockout mice are protected from hyperoxia-induced alveolar simplication
PLOS ONE
Bozyk, PD;Bentley, JK;Popova, AP;Anyanwu, AC;Linn, MD;Goldsmith, AM;Pryhuber, GS;Moore, BB;Hershenson, MB;
2012
22363622
February 24th, 2012
United States
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
Neuromuscular junction defects in mice with mutation of dynein heavy chain 1
PLOS ONE
Courchesne, SL;Pazyra-Murphy, MF;Lee, DJ;Segal, RA;
2011
21346813
February 4th, 2011
United States
Department of Cancer Biology, Dana Farber Cancer Institute, Boston, Massachusetts, United States of America
The nicotinic receptor Alpha7 impacts the mouse lung response to LPS through multiple mechanisms
PLOS ONE
Enioutina, EY;Myers, EJ;Tvrdik, P;Hoidal, JR;Rogers, SW;Gahring, LC;
2015
25803612
March 25th, 2015
United States
Department of Internal Medicine, Division of Geriatrics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America; Department of Pathology, Division of Microbiology and Immunology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America
Generation and Characterisation of a Pax8-CreERT2 Transgenic Line and a Slc22a6-CreERT2 Knock-In Line for Inducible and Specific Genetic Manipulation of Renal Tubular Epithelial Cells
PLOS ONE
Espana-Agusti, J;Zou, X;Wong, K;Fu, B;Yang, F;Tuveson, DA;Adams, DJ;Matakidou, A;
2016
26866916
February 12th, 2016
United Kingdom
Department of Oncology, University of Cambridge, CRUK Cambridge institute, Cambridge, United Kingdom
A neonatal model of intravenous Staphylococcus epidermidis infection in mice <24 h old enables characterization of early innate immune responses
PLOS ONE
Kronforst, KD;Mancuso, CJ;Pettengill, M;Ninkovic, J;Power Coombs, MR;Stevens, C;Otto, M;Mallard, C;Wang, X;Goldmann, D;Levy, O;
2012
22970147
September 12th, 2012
United States
Newborn Medicine, Boston Children's Hospital, Boston, Massachusetts, United States of America
Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis
PLOS ONE
May, SL;Zhou, Q;Lewellen, M;Carter, CM;Coffey, D;Highfill, SL;Bucher, CM;Matise, I;Morse, HC;O'Sullivan, MG;Schutten, M;Johnson, C;Bellgrau, D;Blazar, BR;Modiano, JF;
2014
24945807
June 20th, 2014
United States
Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States of America; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota, United States of America; Integrated Department of Immunology, School of Medicine, University of Colorado, Denver, Colorado, United States of America; University of Colorado Cancer Center, Aurora, Colorado, United States of America
Smad4 loss synergizes with TGFë± overexpression in promoting pancreatic metaplasia, PanIN development, and fibrosis
PLOS ONE
Garcia-Carracedo, D;Yu, CC;Akhavan, N;Fine, SA;Sch̦nleben, F;Maehara, N;Karg, DC;Xie, C;Qiu, W;Fine, RL;Remotti, HE;Su, GH;
2015
25803032
March 25th, 2015
United States
The Department of Pathology, Columbia University Medical Center, New York, New York, United States of America; Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, United States of America; Pancreas Center, Columbia University Medical Center, New York, New York, United States of America; Department of Otolaryngology and Head and Neck Surgery, Columbia University Medical Center, New York, New York, United States of America
CRX is a diagnostic marker of retinal and pineal lineage tumors
PLOS ONE
Santagata, S;Maire, CL;Idbaih, A;Geffers, L;Correll, M;Holton, K;Quackenbush, J;Ligon, KL;
2009
19936203
November 20th, 2009
United States
Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America
Lamellipodin-Deficient Mice: A Model of Rectal Carcinoma
PLOS ONE
Miller, CL;Muthupalani, S;Shen, Z;Drees, F;Ge, Z;Feng, Y;Chen, X;Gong, G;Nagar, KK;Wang, TC;Gertler, FB;Fox, JG;
2016
27045955
April 6th, 2016
United States
Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, United States of America
Insulin and Leptin Signaling Interact in the Mouse Kiss1 Neuron during the Peripubertal Period
PLOS ONE
Qiu, X;Dao, H;Wang, M;Heston, A;Garcia, KM;Sangal, A;Dowling, AR;Faulkner, LD;Molitor, SC;Elias, CF;Hill, JW;
2015
25946091
May 7th, 2015
United States
Center for Diabetes and Endocrine Research, Department of Physiology and Pharmacology, University of Toledo College of Medicine, Toledo, Ohio, United States of America; Department of Obstetrics-Gynecology, University of Toledo College of Medicine, Toledo, Ohio, United States of America
Considerations in the identification of endogenous substrates for protein L-isoaspartyl methyltransferase: the case of synuclein
PLOS ONE
Morrison, GJ;Ganesan, R;Qin, Z;Aswad, DW;
2012
22905247
August 20th, 2012
United States
Department of Molecular Biology & Biochemistry, University of California Irvine, Irvine, California, United States of America
Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage
PLOS ONE
Shearn, CT;Orlicky, DJ;McCullough, RL;Jiang, H;Maclean, KN;Mercer, KE;Stiles, BL;Saba, LM;Ronis, MJ;Petersen, DR;
2016
27124661
April 29th, 2016
United States
Skaggs School of Pharmaceutical Sciences and Pharmacy, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America
Comparative Analysis of Pain Behaviours in Humanized Mouse Models of Sickle Cell Anemia
PLOS ONE
Lei, J;Benson, B;Tran, H;Ofori-Acquah, SF;Gupta, K;
2016
27494522
August 6th, 2016
United States
Vascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, United States of America
Isoaspartate accumulation in mouse brain is associated with altered patterns of protein phosphorylation and acetylation, some of which are highly sex-dependent
PLOS ONE
Qin, Z;Kaufman, RS;Khoury, RN;Khoury, MK;Aswad, DW;
2013
24224061
November 13th, 2013
United States
Department of Molecular Biology & Biochemistry, University of California Irvine, Irvine, California, United States of America
Generation and behavior characterization of CaMKIIë_ knockout mice
PLOS ONE
Bachstetter, AD;Webster, SJ;Tu, T;Goulding, DS;Haiech, J;Watterson, DM;Van Eldik, LJ;
2014
25127391
August 16th, 2014
United States
Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America; Department of Anatomy and Neurobiology, University of Kentucky, Lexington, Kentucky, United States of America
Parental diabetes: the Akita mouse as a model of the effects of maternal and paternal hyperglycemia in wildtype offspring
PLOS ONE
Grasemann, C;Devlin, MJ;Rzeczkowska, PA;Herrmann, R;Horsthemke, B;Hauffa, BP;Grynpas, M;Alm, C;Bouxsein, ML;Palmert, MR;
2012
23209676
December 4th, 2012
Germany
Kinderklinik II, Division of Paediatric Endocrinology, UK- Essen and The University of Duisburg-Essen, Essen, Germany
Digastric Muscle Phenotypes of the Ts65Dn Mouse Model of Down Syndrome
PLOS ONE
Glass, TJ;Connor, NP;
2016
27336944
June 24th, 2016
United States
Department of Surgery, University of Wisconsin, Madison, Wisconsin, United States of America
Rapamycin and chloroquine: the in vitro and in vivo effects of autophagy-modifying drugs show promising results in valosin containing protein multisystem proteinopathy
PLOS ONE
Nalbandian, A;Llewellyn, KJ;Nguyen, C;Yazdi, PG;Kimonis, VE;
2015
25884947
April 18th, 2015
United States
Department of Pediatrics, Division of Genetics and Metabolism, University of California, Irvine, California, United States of America; Sue and Bill Gross Stem Cell Center, University of California, Irvine, California, United States of America
A Fine Balance of Dietary Lipids Improves Pathology of a Murine Model of VCP-Associated Multisystem Proteinopathy
PLOS ONE
Llewellyn, KJ;Walker, N;Nguyen, C;Tan, B;BenMohamed, L;Kimonis, VE;Nalbandian, A;
2015
26134519
July 3rd, 2015
United States
Department of Pediatrics, Division of Genetics and Genomics Medicine, University of California Irvine, Irvine, CA, 92697, United States of America; Sue and Bill Gross Stem Institute, University of California Irvine, Irvine, CA, 92697, United States of America
Cholecystokinin: an excitatory modulator of mitral/tufted cells in the mouse olfactory bulb
PLOS ONE
Ma, J;Dankulich-Nagrudny, L;Lowe, G;
2013
23691163
May 21st, 2013
United States
Monell Chemical Senses Center, Philadelphia, Pennsylvania, United States of America
Mechanism of testosterone deficiency in the transgenic sickle cell mouse
PLOS ONE
Musicki, B;Zhang, Y;Chen, H;Brown, TR;Zirkin, BR;Burnett, AL;
2015
26023917
May 30th, 2015
United States
The James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America
Novel marker for the onset of frontotemporal dementia: early increase in activity-dependent neuroprotective protein (ADNP) in the face of Tau mutation
PLOS ONE
Schirer, Y;Malishkevich, A;Ophir, Y;Lewis, J;Giladi, E;Gozes, I;
2014
24489906
February 3rd, 2014
Israel
The Adams Super Center for Brain Studies, The Lily and Avraham Gildor Chair for the Investigation of Growth Factors, The Elton Laboratory for Neuroendocrinology, Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel
Intrinsic susceptibility MRI identifies tumors with ALKF1174L mutation in genetically-engineered murine models of high-risk neuroblastoma
PLOS ONE
Jamin, Y;Glass, L;Hallsworth, A;George, R;Koh, DM;Pearson, AD;Chesler, L;Robinson, SP;
2014
24667968
March 26th, 2014
United Kingdom
Division of Radiotherapy and Imaging, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, United Kingdom
The effects of C75, an inhibitor of fatty acid synthase, on sleep and metabolism in mice
PLOS ONE
Pellinen, J;Szentirmai, Ìä;
2012
22348016
February 20th, 2012
United States
Washington, Wyoming, Alaska, Montana and Idaho, Medical Education Program, Washington State University, Spokane, Washington, United States of America
A reinforcing circuit action of extrasynaptic GABAA receptor modulators on cerebellar granule cell inhibition
PLOS ONE
Santhakumar, V;Meera, P;Karakossian, MH;Otis, TS;
2013
23977374
August 26th, 2013
United States
Department of Neurobiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America
Cranial irradiation alters the brain's microenvironment and permits CCR2+ macrophage infiltration
PLOS ONE
Morganti, JM;Jopson, TD;Liu, S;Gupta, N;Rosi, S;
2014
24695541
April 3rd, 2014
United States
Brain and Spinal Injury Center, University of California San Francisco, San Francisco, California, United States of America; Departments of Physical Therapy and Rehabilitation Science, University of California San Francisco, San Francisco, California, United States of America; Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America
Deficiency in p38ë_ MAPK fails to inhibit cytokine production or protect neurons against inflammatory insult in in vitro and in vivo mouse models
PLOS ONE
Xing, B;Bachstetter, AD;Van Eldik, LJ;
2013
23457629
March 4th, 2013
United States
Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America
Hilar somatostatin interneurons contribute to synchronized GABA activity in an in vitro epilepsy model
PLOS ONE
Grosser, S;Queenan, BN;Lalchandani, RR;Vicini, S;
2014
24465989
January 27th, 2014
United States
Department of Pharmacology and Physiology, Georgetown University, Washington, District of Columbia, United States of America ; Interdisciplinary Program in Neuroscience, Georgetown University, Washington, District of Columbia, United States of America
RDH10 oxidation of Vitamin A is a critical control step in synthesis of retinoic acid during mouse embryogenesis
PLOS ONE
Sandell, LL;Lynn, ML;Inman, KE;McDowell, W;Trainor, PA;
2012
22319578
February 9th, 2012
United States
Stowers Institute for Medical Research, Kansas City, Missouri, United States of America
7 Nicotinic receptor-mediated astrocytic gliotransmitter release: A effects in a preclinical Alzheimer's mouse model
PLOS ONE
Pirttimaki, TM;Codadu, NK;Awni, A;Pratik, P;Nagel, DA;Hill, EJ;Dineley, KT;Parri, HR;
2013
November 28th, 2013
United States
School of Life and Health Sciences, Aston University
Comprehensive analysis of ultrasonic vocalizations in a mouse model of fragile X syndrome reveals limited, call type specific deficits
PLOS ONE
Roy, S;Watkins, N;Heck, D;
2012
22984567
September 17th, 2012
United States
Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
GPR40 and GPR120 fatty acid sensors are critical for postoral but not oral mediation of fat preferences in the mouse
American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Sclafani, A;Zukerman, S;Ackroff, K;
2013
24154510
December 15th, 2013
United States
Department of Psychology, Brooklyn College, City University of New York, Brooklyn, New York, and
P2X7 receptors in body temperature, locomotor activity, and brain mRNA and lncRNA responses to sleep deprivation
American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Davis, CJ;Taishi, P;Honn, KA;Koberstein, JN;Krueger, JM;
2016
27707719
December 1st, 2016
United States
Elson S. Floyd College of Medicine, Department of Biomedical Sciences, Washington State University-Spokane, Spokane, Washington
Sugar-induced cephalic-phase insulin release is mediated by a T1r2+T1r3-independent taste transduction pathway in mice
American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Glendinning, JI;Stano, S;Holter, M;Azenkot, T;Goldman, O;Margolskee, RF;Vasselli, JR;Sclafani, A;
2015
26157055
September 1st, 2015
United States
Department of Biology, Barnard College, Columbia University, New York, New York
Restricted feeding-induced sleep, activity, and body temperature changes in normal and preproghrelin-deficient mice
American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Szentirmai, E;KapÃŒÃs, L;Sun, Y;Smith, RG;Krueger, JM;
2010
19939974
February 1st, 2010
United States
WWAMI Medical Education Program, Washington State Univ., Spokane, P.O. Box 1495, Spokane, WA 99210-1495, USA
Spontaneous sleep and homeostatic sleep regulation in ghrelin knockout mice
American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Szentirmai, E;KapÃŒÃs, L;Sun, Y;Smith, RG;Krueger, JM;
2007
17409264
July 1st, 2007
United States
Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology, Program in Neuroscience, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6520, USA
SOD1-G93A mice exhibit muscle-fiber-type-specific decreases in glucose uptake in the absence of whole-body changes in metabolism
Neuro-degenerative Diseases
Smittkamp, SE;Morris, JK;Bomhoff, GL;Chertoff, ME;Geiger, PC;Stanford, JA;
2014
24021858
December 20th, 2014
United States
Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kans., USA
Effects of stimulus salience on touchscreen serial reversal learning in a mouse model of fragile X syndrome
Behavioral Brain Research
Dickson, PE;Corkill, B;McKimm, E;Miller, MM;Calton, MA;Goldowitz, D;Blaha, CD;Mittleman, G;
2013
23747611
September 1st, 2013
United States
The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
Sustained attention in mice: expanding the translational utility of the SAT by incorporating the Michigan Controlled Access Response Port (MICARP)
Behavioral Brain Research
St Peters, M;Cherian, AK;Bradshaw, M;Sarter, M;
2011
21888929
December 1st, 2011
United States
Department of Psychology, University of Michigan, Ann Arbor, MI 48109-8862, United States
A novel role for the immunophilin FKBP52 in motor coordination
Behavioral Brain Research
Young, MJ;Geiszler, PC;Pardon, MC;
2016
27418439
October 15th, 2016
United Kingdom
University of Nottingham Medical School, School of Life Sciences, Neuroscience group, Queen's Medical Centre, Nottingham NG7 2UH United Kingdom
Neuronal nitric oxide synthase and NADPH oxidase interact to affect cognitive, affective, and social behaviors in mice
Behavioral Brain Research
Walton, JC;Selvakumar, B;Weil, ZM;Snyder, SH;Nelson, RJ;
2013
23948215
November 1st, 2013
United States
Department of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA
Measures of bulbar and spinal motor function, muscle innervation, and mitochondrial function in ALS rats
Behavioral Brain Research
Smittkamp, SE;Spalding, HN;Brown, JW;Gupte, AA;Chen, J;Nishimune, H;Geiger, PC;Stanford, JA;
2010
20211206
July 29th, 2010
United States
Department of Molecular & Integrative Physiology, University of Kansas Medical Center, Kansas City, KS 66160, United States
Spatial frequency threshold and contrast sensitivity of an optomotor behavior are impaired in the Ins2Akita mouse model of diabetes
Behavioral Brain Research
Akimov, NP;RenterÌ_a, RC;
2012
21963766
January 15th, 2012
United States
Department of Physiology and Center for Biomedical Neuroscience, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, United States
Molecular and behavioral profiling of Dbx1-derived neurons in the arcuate, lateral and ventromedial hypothalamic nuclei
Neural Development
Sokolowski, K;Tran, T;Esumi, S;Kamal, Y;Oboti, L;Lischinsky, J;Goodrich, M;Lam, A;Carter, M;Nakagawa, Y;Corbin, JG;
2016
27209204
May 21st, 2016
United States
Center for Neuroscience Research, Children's National Medical Center, 111 Michigan Avenue, NW, Washington, 20010, DC, USA
Common and unique genetic interactions of the poly(ADP-ribose) polymerases PARP1 and PARP2 with DNA double-strand break repair pathways
DNA Repair
Ghosh, R;Roy, S;Kamyab, J;Dantzer, F;Franco, S;
2016
27373144
September 1st, 2016
United States
Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21287, United States
In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice
Drug Metabolism and Disposition
Yasuda, K;Cline, C;Lin, YS;Scheib, R;Ganguly, S;Thirumaran, RK;Chaudhry, A;Kim, RB;Schuetz, EG;
2015
26281846
November 1st, 2015
United States
Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee (K.Y., C.C., R.S., S.G., R.K.T., A.C., E.G.S.); Department of Medicine, Division of Clinical Pharmacology, University of Western Ontario, London, Ontario, Canada (R.B.K.); and Department of Pharmaceutics, The University of Washington, Seattle, Washington (Y.S.L.)
Pharmacokinetics of oral D-serine in D-amino acid oxidase knockout mice
Drug Metabolism and Disposition
Rais, R;Thomas, AG;Wozniak, K;Wu, Y;Jaaro-Peled, H;Sawa, A;Strick, CA;Engle, SJ;Brandon, NJ;Rojas, C;Slusher, BS;Tsukamoto, T;
2012
22837388
November 1st, 2012
United States
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Separation of function for classical and ganglion cell photoreceptors with respect to circadian rhythm entrainment and induction of photosomnolence
Neuroscience
Morin, LP;Studholme, KM;
2011
21985934
December 29th, 2011
United States
Department of Psychiatry, Stony Brook University Medical Center, Stony Brook, NY, USA
Activation of the Wnt/ë_-catenin signaling cascade after traumatic nerve injury
Neuroscience
Kurimoto, S;Jung, J;Tapadia, M;Lengfeld, J;Agalliu, D;Waterman, M;Mozaffar, T;Gupta, R;
2015
25743255
May 21st, 2015
United States
Department of Orthopaedic Surgery, University of California, Irvine, CA 92697, USA; Department of Hand Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-Cho, Showa-Ku, Nagoya 466-8550, Japan
Distinct mechanisms of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine resistance revealed by transcriptome mapping in mouse striatum
Neuroscience
Pattarini, R;Rong, Y;Qu, C;Morgan, JI;
2008
18675323
September 1st, 2008
United States
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105-3678, USA
Nuclear Thioredoxin-1 Overexpression Attenuates Alcohol-Mediated Nrf2 Signaling and Lung Fibrosis
Alcoholism Clinical and Experimental Research
Sueblinvong, V;Mills, ST;Neujahr, DC;Go, YM;Jones, DP;Guidot, DM;
2016
27436123
September 1st, 2016
United States
Division of Pulmonary, Allergy & Critical Care, Department of Medicine, Atlanta, Georgia
Effects of Gabra2 Point Mutations on Alcohol Intake: Increased Binge-Like and Blunted Chronic Drinking by Mice
Alcoholism Clinical and Experimental Research
Newman, EL;Gunner, G;Huynh, P;Gachette, D;Moss, SJ;Smart, TG;Rudolph, U;DeBold, JF;Miczek, KA;
2016
27717041
November 1st, 2016
United States
Department of Psychology, Tufts University, Medford, Massachusetts. , ELnewman@gmail.com
Galanin knockout mice show disturbances in ethanol consumption and expression of hypothalamic peptides that stimulate ethanol intake
Alcoholism Clinical and Experimental Research
Karatayev, O;Baylan, J;Weed, V;Chang, S;Wynick, D;Leibowitz, SF;
2010
19860804
January 1st, 2010
United States
Laboratory of Behavioral Neurobiology, Rockefeller University, New York, New York, USA
Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication
Virology
Hodgson, AJ;Hyser, JM;Keasler, VV;Cang, Y;Slagle, BL;
2012
22342275
April 25th, 2012
United States
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA
Fragile X mental retardation protein regulates olfactory sensitivity but not odorant discrimination
Chemical Senses
Schilit Nitenson, A;Stackpole, EE;Truszkowski, TL;Midroit, M;Fallon, JR;Bath, KG;
2015
25917509
June 1st, 2015
United States
Department of Neuroscience, Brown University, 185 Meeting Street, Providence, RI 02912, USA, Department of Cognitive, Linguistic and Psychological Sciences, Brown University, 190 Thayer Street, Providence, RI 02912, USA
Salty taste deficits in CALHM1 knockout mice
Chemical Senses
Tordoff, MG;Ellis, HT;Aleman, TR;Downing, A;Marambaud, P;Foskett, JK;Dana, RM;McCaughey, SA;
2014
24846212
July 1st, 2014
United States
Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104, USA
Normal Taste Acceptance and Preference of PANX1 Knockout Mice
Chemical Senses
Tordoff, MG;Aleman, TR;Ellis, HT;Ohmoto, M;Matsumoto, I;Shestopalov, VI;Mitchell, CH;Foskett, JK;Poole, RL;
2015
25987548
September 1st, 2015
United States
Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104, USA
Heightened avidity for trisodium pyrophosphate in mice lacking Tas1r3
Chemical Senses
Tordoff, MG;Aleman, TR;McCaughey, SA;
2015
25452580
January 1st, 2015
United States
Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104, USA and
Ectopic POU5F1 in the male germ lineage disrupts differentiation and spermatogenesis in mice
Reproduction
Zheng, Y;Phillips, LJ;Hartman, R;An, J;Dann, CT;
2016
27486267
October 1st, 2016
United States
Department of ChemistryIndiana University, Bloomington, Indiana, USA
Comprehensive motor testing in Fmr1-KO mice exposes temporal defects in oromotor coordination
Behavioral Neuroscience
Roy, S;Zhao, Y;Allensworth, M;Farook, MF;LeDoux, MS;Reiter, LT;Heck, DH;
2011
22004265
December 1st, 2011
United States
Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
Aryl hydrocarbon receptor knockout rats are insensitive to the pathological effects of repeated oral exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
Journal of Applied Toxicology
Harrill, JA;Layko, D;Nyska, A;Hukkanen, RR;Manno, RA;Grassetti, A;Lawson, M;Martin, G;Budinsky, RA;Rowlands, JC;Thomas, RS;
2016
26278112
June 1st, 2016
United States
The Hamner Institutes for Health Sciences, Institute for Chemical Safety Sciences, Research Triangle Park, NC, 27709, USA
Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis
Journal of Sexual Medicine
Musicki, B;Bivalacqua, TJ;Champion, HC;Burnett, AL;
2014
24251665
February 1st, 2014
United States
The James Buchanan Brady Urological Institute, Department of Urology, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Post-translational inactivation of endothelial nitric oxide synthase in the transgenic sickle cell mouse penis
Journal of Sexual Medicine
Musicki, B;Champion, HC;Hsu, LL;Bivalacqua, TJ;Burnett, AL;
2011
21143412
February 1st, 2011
United States
The Johns Hopkins University, Department of Urology, Baltimore, MD 21287, USA
Extracellular sodium and potassium levels modulate cardiac conduction in mice heterozygous null for the Connexin43 gene
Pflugers Archiv - European Journal of Physiology
George, SA;Sciuto, KJ;Lin, J;Salama, ME;Keener, JP;Gourdie, RG;Poelzing, S;
2015
25771952
November 1st, 2015
United States
Department of Biomedical Engineering and Mechanics, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA
Astrocytic group I mGluR-dependent potentiation of astrocytic glutamate and potassium uptake
Journal of Neurophysiology
Devaraju, P;Sun, MY;Myers, TL;Lauderdale, K;Fiacco, TA;
2013
23427307
May 1st, 2013
United States
Department of Cell Biology and Neuroscience, University of California, Riverside, CA, USA
pigk Mutation underlies macho behavior and affects Rohon-Beard cell excitability
Journal of Neurophysiology
Carmean, V;Yonkers, MA;Tellez, MB;Willer, JR;Willer, GB;Gregg, RG;Geisler, R;Neuhauss, SC;Ribera, AB;
2015
26133798
August 1st, 2015
United States
Neuroscience Program, University of Colorado Anschutz Medical Campus, Aurora, Colorado; Department of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, Colorado
PACAP modulation of calcium ion activity in developing granule cells of the neonatal mouse olfactory bulb
Journal of Neurophysiology
Irwin, M;Greig, A;Tvrdik, P;Lucero, MT;
2015
25475351
February 15th, 2015
United States
Department of Physiology, University of Utah School of Medicine, Salt Lake City, Utah; Interdepartmental Neuroscience Program, University of Utah School of Medicine, Salt Lake City, Utah; and Department of Neuroscience and Physiology, American University of the Caribbean, Cupecoy, Sint Maarten, Netherlands Antilles
Impact of inhibitory constraint of interneurons on neuronal excitability
Journal of Neurophysiology
Lee, V;Maguire, J;
2013
24027099
December 1st, 2013
United States
Medical Scientist Training Program and Graduate Program in Neuroscience, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts; and
Intragastric fat self-administration is impaired in GPR40/120 double knockout mice
Physiology and Behavior
Sclafani, A;Touzani, K;Ackroff, K;
2015
25911263
August 1st, 2015
United States
Brooklyn College of CUNY, Brooklyn, NY, USA
MCH receptor deletion does not impair glucose-conditioned flavor preferences in mice
Physiology and Behavior
Sclafani, A;Adamantidis, A;Ackroff, K;
2016
27195455
September 1st, 2016
United States
Department of Psychology, Brooklyn College of the City University of New York, Brooklyn, NY, USA; Behavioral and Cognitive Neuroscience Cluster, Psychology Doctoral Program, The Graduate School, City University of New York, New York, NY, USA
Ghrelin signaling is not essential for sugar or fat conditioned flavor preferences in mice
Physiology and Behavior
Sclafani, A;Touzani, K;Ackroff, K;
2015
26003495
October 1st, 2015
United States
Brooklyn College of CUNY, Brooklyn, NY, USA
Macronutrient selection by seven inbred mouse strains and three taste-related knockout strains
Physiology and Behavior
Tordoff, MG;Downing, A;Voznesenskaya, A;
2014
24912134
August 1st, 2014
United States
Monell Chemical Senses Center, Philadelphia, PA 19194, USA
Sucrose-conditioned flavor preferences in sweet ageusic T1r3 and Calhm1 knockout mice
Physiology and Behavior
Sclafani, A;Marambaud, P;Ackroff, K;
2014
24384370
March 14th, 2014
United States
Department of Psychology, Brooklyn College, City University of New York, Brooklyn, NY 11210, USA
Retinal macroglia changes in a triple transgenic mouse model of Alzheimer's disease
Experimental Eye Research
Edwards, MM;RodrÌ_guez, JJ;Gutierrez-Lanza, R;Yates, J;Verkhratsky, A;Lutty, GA;
2014
25149907
October 1st, 2014
United States
Wilmer Eye Institute, Johns Hopkins Hospital, M023 Smith Building, 400 N. Broadway, Baltimore, MD 21287, USA
Intact Toll-like receptor 9 signaling in neutrophils modulates normal thrombogenesis in mice
Journal of Vasuclar Surgery
El-Sayed, OM;Dewyer, NA;Luke, CE;Elfline, M;Laser, A;Hogaboam, C;Kunkel, SL;Henke, PK;
2016
26482993
November 1st, 2016
United States
Department of Vascular Surgery, University of Michigan Medical School, Ann Arbor, Mich
Morphine-induced antinociception and reward in humanized mice expressing the mu opioid receptor A118G polymorphism
Brain Research Bulletin
Henderson-Redmond, AN;Yuill, MB;Lowe, TE;Kline, AM;Zee, ML;Guindon, J;Morgan, DJ;
2016
26521067
May 1st, 2016
United States
Department of Pharmacology and Neuroscience, Texas Tech University Health Science Center, Lubbock, TX 79430, United States
Altered gamma oscillations during pregnancy through loss of ë« subunit-containing GABA(A) receptors on parvalbumin interneurons
Frontiers in Neural Circuits
Ferando, I;Mody, I;
2013
24062647
September 24th, 2013
United States
Department of Neurology, The David Geffen School of Medicine, University of California Los Angeles, CA 90095-733522, USA
Severe drug-induced repetitive behaviors and striatal overexpression of VAChT in ChAT-ChR2-EYFP BAC transgenic mice
Frontiers in Neural Circuits
Crittenden, JR;Lacey, CJ;Lee, T;Bowden, HA;Graybiel, AM;
2014
24904300
June 6th, 2014
United States
Department of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology Cambridge, MA, USA
Distinct roles of synaptic and extrasynaptic GABAAreceptors in striatal inhibition dynamics
Frontiers in Neural Circuits
Luo, R;Partridge, JG;Vicini, S;
2013
24324406
December 10th, 2013
United States
Department of Pharmacology and Physiology, Georgetown University School of Medicine Washington, DC, USA
Cerebellar Nuclei Neurons Show Only Small Excitatory Responses to Optogenetic Olivary Stimulation in Transgenic Mice: In Vivo and In Vitro Studies
Frontiers in Neural Circuits
Lu, H;Yang, B;Jaeger, D;
2016
27047344
April 6th, 2016
United States
Department of Biomedical Sciences, Philadelphia College of Osteopathic Medicine-Georgia CampusSuwannee, GA, USA; Department of Biology, Emory UniversityAtlanta, GA, USA
Conditional knockout of myocyte focal adhesion kinase abrogates ischemic preconditioning in adult murine hearts
Journal of American Heart Association
Perricone, AJ;Bivona, BJ;Jackson, FR;Vander Heide, RS;
2013
24080910
September 30th, 2013
United States
Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, LA
Reorganization of circuits underlying cerebellar modulation of prefrontal cortical dopamine in mouse models of autism spectrum disorder
Cerebellum
Rogers, TD;Dickson, PE;McKimm, E;Heck, DH;Goldowitz, D;Blaha, CD;Mittleman, G;
2013
23436049
August 1st, 2013
United States
Department of Psychology, University of Memphis, Memphis, TN 38152-6400, USA
E-prostanoid 2 receptor signaling suppresses lung innate immunity against Streptococcus pneumoniae
Prostaglandins Other Lipid Mediators
Aronoff, DM;Bergin, IL;Lewis, C;Goel, D;O'Brien, E;Peters-Golden, M;Mancuso, P;
2012
22575745
May 1st, 2012
United States
Divisions of Infectious Diseases, The University of Michigan, Ann Arbor, MI 48109-5680, United States
Non-invasive quantification of brain tumor-induced astrogliosis
BMC Neuroscience
Lee, J;Borboa, AK;Baird, A;Eliceiri, BP;
2011
21247490
January 19th, 2011
United States
Department of Surgery, University of California San Diego, San Diego, CA, USA
Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis
Brain Research
Lopez, AM;Chuang, JC;Posey, KS;Turley, SD;
2017
27789278
January 1st, 2017
United States
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Long-term improvements in sensory inhibition with gestational choline supplementation linked to 7 nicotinic receptors through studies in Chrna7 null mutation mice
Brain Research
Stevens, KE;Choo, KS;Stitzel, JA;Marks, MJ;Adams, CE;
2014
March 13th, 2014
United States
Medical Research Service, Veterans Affairs Medical Center, Denver, CO, USA
Taste dysfunction in BTBR mice due to a mutation of Itpr3, the inositol triphosphate receptor 3 gene
Physiological Genomics
Tordoff, MG;Ellis, HT;
2013
23859941
September 16th, 2013
United States
Monell Chemical Senses Center, Philadelphia, Pennsylvania
Involvement of T1R3 in calcium-magnesium taste
Physiological Genomics
Tordoff, MG;Shao, H;AlarcÌ_n, LK;Margolskee, RF;Mosinger, B;Bachmanov, AA;Reed, DR;McCaughey, S;
2008
18593862
August 15th, 2008
United States
Monell Chemical Senses Center, Philadelphia, Pennsylvania 19104-3308, USA
Lipoprotein(a) and vitamin C impair development of breast cancer tumors in Lp(a)+; Gulo-/- mice
International Journal of Oncology
Cha, J;Roomi, MW;Kalinovsky, T;Niedzwiecki, A;Rath, M;
2016
27573077
September 1st, 2016
United States
Dr. Rath Research Institute, Santa Clara, CA 95050, USA
Ascorbate supplementation inhibits growth and metastasis of B16FO melanoma and 4T1 breast cancer cells in vitamin C-deficient mice
International Journal of Oncology
Cha, J;Roomi, MW;Ivanov, V;Kalinovsky, T;Niedzwiecki, A;Rath, M;
2013
23175106
January 1st, 2013
United States
Dr Rath Research Institute, Santa Clara, CA 95050, USA
Inhibition of neuronal p38ë±, but not p38ë_ MAPK, provides neuroprotection against three different neurotoxic insults
Journal of Molecular Neuroscience
Xing, B;Bachstetter, AD;Van Eldik, LJ;
2015
25012593
February 1st, 2015
United States
Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, 40536, USA
Abstracts of the 10th International Symposium on VIP-PACAP and Related Peptides. December 13-16, 2011. Eilat, Israel
Journal of Molecular Neuroscience
Unknown, ;
2012
22144041
November 1st, 2012
Israel
The Israel Society for Neuroscience Meeting
Lentiviral-based approach for the validation of cancer therapeutic targets in vivo
BioTechniques
Ambrogio, C;Stern, P;Scuoppo, C;Kranz, H;Barbacid, M;SantamarÌ_a, D;
2014
25312087
October 1st, 2014
Spain
Molecular Oncology Programme, Centro Nacional de Investigaciones OncolÌ_gicas (CNIO), Spanish National Cancer Research Center, Madrid, Spain
Intravital live cell triggered imaging system reveals monocyte patrolling and macrophage migration in atherosclerotic arteries
Journal of Biomedical Optics
McArdle, S;Chodaczek, G;Ray, N;Ley, K;
2015
25710308
February 1st, 2015
United States
La Jolla Institute, 9420 Athena Circle, La Jolla, California 92037, United States
Knockout of p11 attenuates the acquisition and reinstatement of cocaine conditioned place preference in male but not in female mice
Synapse
Thanos, PK;Malave, L;Delis, F;Mangine, P;Kane, K;Grunseich, A;Vitale, M;Greengard, P;Volkow, ND;
2016
26990537
July 1st, 2016
United States
Behavioral Neuropharmacology and Neuroimaging Laboratory on Addictions, Research Institute on Addictions, University at Buffalo, Buffalo, New York
Evaluation of [Ã¥_‰ÂüF]PFH PET renography to predict future disease progression in a rat model of autosomal dominant polycystic kidney disease
Nuclear Medicine and Biology
Pathuri, G;Hedrick, AF;Awasthi, V;Cowley, BD;Gali, H;
2016
26702780
January 1st, 2016
United States
Department of Pharmaceutical Sciences, College of Pharmacy, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
Quantification of pain in sickle mice using facial expressions and body measurements
Blood Cells, Molecules, and Diseases
Mittal, A;Gupta, M;Lamarre, Y;Jahagirdar, B;Gupta, K;
2016
26852657
March 1st, 2016
United States
Vascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN, USA
Utrophin suppresses low frequency oscillations and coupled gating of mechanosensitive ion channels in dystrophic skeletal muscle
Channels (Austin)
Lansman, JB;
2015
25941878
June 13th, 2015
United States
a Department of Cellular and Molecular Pharmacology ; School of Medicine; University of California San Francisco; San Francisco , CA USA
A progressive translational mouse model of human valosin-containing protein disease: the VCP(R155H/+) mouse
Muscle Nerve
Nalbandian, A;Llewellyn, KJ;Badadani, M;Yin, HZ;Nguyen, C;Katheria, V;Watts, G;Mukherjee, J;Vesa, J;Caiozzo, V;Mozaffar, T;Weiss, JH;Kimonis, VE;
2013
23169451
February 1st, 2013
United States
Department of Pediatrics, Division of Genetics and Metabolism, 2501 Hewitt Hall, University of California, Irvine, Irvine, California 92696, USA
Circadian rhythmicity in serotonin transporter knockout mice
Life Sciences
Pang, RD;Holschneider, DP;Miller, JD;
2012
22884802
October 1st, 2012
United States
Graduate Program in Neuroscience, University of Southern California, CA 90033, United States
Protection against vascular leak in neprilysin transgenic mice with complexåÊoverexpressionåÊpattern
Transgenic Research
Wick, MJ;Loomis, ZL;Harral, JW;Le, M;Wehling, CA;Miller, YE;Dempsey, EC;
2016
27369050
December 1st, 2016
United States
Cardiovascular Pulmonary Research Laboratory, University of Colorado Denver, RC-2, Box B-133, 12700 E. 19th Ave., Aurora, CO, 80045, USA
A germline-competent embryonic stem cell line from NOD.Cg-Prkdc ( scid ) Il2rg ( tm1Wjl )/SzJ (NSG) mice
Transgenic Research
Landel, CP;Dunlap, J;Patton, JB;Manser, T;
2013
22767020
February 1st, 2013
United States
Department of Microbiology and Immunology, Thomas Jefferson University, 233 S. 10th St, Philadelphia, PA 19107, USA
Effects of SB-269970, a 5-HT7 receptor antagonist, in mouse models predictive of antipsychotic-like activity
Behavioral Pharmacology
Galici, R;Boggs, JD;Miller, KL;Bonaventure, P;Atack, JR;
2008
18332680
March 1st, 2008
United States
Johnson & Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA
Inducible cell labeling and lineage tracking during fracture repair
Development, Growth, and Differentiation
Seime, T;Kolind, M;Mikulec, K;Summers, MA;Cantrill, L;Little, DG;Schindeler, A;
2015
25389084
January 1st, 2015
Australia
Department of Orthopaedic Research & Biotechnology, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, Sydney, NSW, 2145, Australia; MCI Management Center Innsbruck, A-6020 Innsbruck, Austria
Global gene expression profiling in R155H knock-in murine model of VCP disease
Clinical Transltional Science
Nalbandian, A;Ghimbovschi, S;Wang, Z;Knoblach, S;Llewellyn, KJ;Vesa, J;Hoffman, EP;Kimonis, VE;
2015
25388089
February 1st, 2015
United States
Department of Pediatrics, Division of Genetics and Metabolism, University of California-Irvine, Irvine, California, USA
ZASC1 knockout mice exhibit an early bone marrow-specific defect in murine leukemia virus replication
Virology Journal
Seidel, S;Bruce, J;Leblanc, M;Lee, KF;Fan, H;Ahlquist, P;Young, JA;
2013
23617998
April 24th, 2013
United States
Nomis Center for Immunobiology and Microbial Pathogenesis, The Salk Institute for Biological Studies, La Jolla, CA, USA
Anticonvulsant effects of the selective melatonin receptor agonist ramelteon
Epilepsy and Behavior
Fenoglio-Simeone, K;Mazarati, A;Sefidvash-Hockley, S;Shin, D;Wilke, J;Milligan, H;Sankar, R;Rho, JM;Maganti, R;
2009
19682955
September 1st, 2009
United States
Creighton University School of Medicine, Omaha, NE, USA
Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure
American Journal of Medical Genetics Part A
Rogers, SW;Tvrdik, P;Capecchi, MR;Gahring, LC;
2012
22473653
May 1st, 2012
United States
Salt Lake City VA Geriatric Research, Education and Clinical Center, Salt Lake City, Utah, USA
Megaesophagus in a line of transgenic rats: a model of achalasia
Veterinary Pathology
Pang, J;Borjeson, TM;Muthupalani, S;Ducore, RM;Carr, CA;Feng, Y;Sullivan, MP;Cristofaro, V;Luo, J;Lindstrom, JM;Fox, JG;
2014
24457157
November 1st, 2014
United States
Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA
Increased intake of ethanol and dietary fat in galanin overexpressing mice
Alcohol
Karatayev, O;Baylan, J;Leibowitz, SF;
2009
20004335
December 1st, 2009
United States
Laboratory of Behavioral Neurobiology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice
Regulatory Peptides
Longo, KA;Charoenthongtrakul, S;Giuliana, DJ;Govek, EK;McDonagh, T;Qi, Y;DiStefano, PS;Geddes, BJ;
2008
18453014
October 1st, 2008
United States
Elixir Pharmaceuticals, Inc., 12 Emily St., Cambridge, MA 02139, United States
Bacterial load and inflammation in fetal tissues is not dependent on IL-17a or IL-22 in 10-14 day pregnant mice infected with Listeria monocytogenes
Microbial Pathogenesis
Poulsen, KP;Faith, NG;Steinberg, H;Czuprynski, CJ;
2013
23178254
March 1st, 2013
United States
Department of Clinical Sciences, College of Veterinary Medicine, Oregon State University, 700 SW 30th Street, Corvallis, OR 97331, USA
Multiple ERbeta antisera label in ERbeta knockout and null mouse tissues
Journal of Neuroscience Methods
Snyder, MA;Smejkalova, T;Forlano, PM;Woolley, CS;
2010
20170675
May 15th, 2010
United States
Department of Neurobiology and Physiology, Northwestern University, 2205 Tech Drive, Evanston, IL 60208, USA
Prediction of death in the SMNëÓ7 mouse model of spinal muscular atrophy: insight into disease stage and progression
Journal of Neuroscience Methods
El-Khodor, BF;Cirillo, K;Beltran, JA;Mushlin, R;Winberg, ML;Charney, R;Chomicova, O;Marino, T;Ramboz, S;
2012
22750651
August 15th, 2012
United States
PsychoGenics Inc., 765 Old Sawmill River Road, Tarrytown, NY 10591, United States
Activation of the NLRP3 Inflammasome Is Associated with Valosin-Containing Protein Myopathy
Inflammation
Nalbandian, A;Khan, AA;Srivastava, R;Llewellyn, KJ;Tan, B;Shukr, N;Fazli, Y;Kimonis, VE;BenMohamed, L;
2016
27730320
October 11th, 2016
United States
Laboratory of Cellular and Molecular Immunology, Gavin Herbert Institute, School of Medicine, University of California Irvine, Irvine, CA, 92697, USA
Attenuated Salmonella enterica Typhimurium reduces tumor burden in an autochthonous breast cancer model
Anticancer Research
Drees, J;Mertensotto, M;Liu, G;Panyam, J;Leonard, A;Augustin, L;Schottel, J;Saltzman, D;
2015
25667465
February 1st, 2015
United States
Department of Surgery, University of Minnesota, Minneapolis, MN, U.S.A
Maneb causes pro-oxidant effects in the hippocampus of Nrf2 knockout mice
Environ.mental Toxicology and Pharmacology
Kurzatkowski, DM;Trombetta, LD;
2013
23764462
September 1st, 2013
United States
Department of Pharmaceutical Sciences, St. John's University, 8000 Utopia Parkway, Queens, NY 11439, USA
Osteopontin does not mitigate cisplatin ototoxicity or nephrotoxicity in adult mice
Otolaryngology - Head and Neck Surgery
Schmitt, NC;Rubel, EW;
2013
23884286
October 1st, 2013
United States
Virginia Merrill Bloedel Hearing Research Center, Seattle, Washington, USA
Relationship between circadian period and body size in the tau-mutant golden hamster
Canadian Journal of Physiology and Pharmacology
Refinetti, R;
2014
24383870
January 1st, 2014
United States
Circadian Rhythm Laboratory, University of South Carolina, 807 Hampton Street, Walterboro, SC 29488, USA
A comparative assessment of the cytotoxicity and nitric oxide reducing ability of resveratrol, pterostilbene and piceatannol in transformed and normal mouse macrophages
Drug and Chemical Toxicology
Adiabouah Achy-Brou, CA;Billack, B;
2016
27079867
April 14th, 2016
United States
a Department of Pharmaceutical Sciences , College of Pharmacy and Health Sciences, St. John's University , Jamaica , NY , USA
Cannabinoid receptor-specific mechanisms to alleviate pain in sickle cell anemia via inhibition of mast cell activation and neurogenic inflammation
Haematologica
Vincent, L;Vang, D;Nguyen, J;Benson, B;Lei, J;Gupta, K;
2016
26703965
May 1st, 2016
United States
Vascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN, USA
Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease
Science Signaling
Pryor, WM;Biagioli, M;Shahani, N;Swarnkar, S;Huang, WC;Page, DT;MacDonald, ME;Subramaniam, S;
2014
25351248
October 28th, 2014
United States
Department of Neuroscience, The Scripps Research Institute Florida, Jupiter, FL 33458, USA
SLC26A4 targeted to the endolymphatic sac rescues hearing and balance in Slc26a4 mutant mice
PLOS Genetics
Li, X;Sanneman, JD;Harbidge, DG;Zhou, F;Ito, T;Nelson, R;Picard, N;Chambrey, R;Eladari, D;Miesner, T;Griffith, AJ;Marcus, DC;Wangemann, P;
2013
23874234
July 22nd, 2013
United States
Anatomy & Physiology Department, Kansas State University, Manhattan, Kansas, USA
Interaction between Foxc1 and Fgf8 during mammalian jaw patterning and in the pathogenesis of syngnathia
PLOS Genetics
Inman, KE;Purcell, P;Kume, T;Trainor, PA;
2013
24385915
January 3rd, 2013
United States
Stowers Institute for Medical Research, Kansas City, Missouri, United States of America
Transient Loss of Protection Afforded by a Live Attenuated Non-typhoidal Salmonella Vaccine in Mice Co-infected with Malaria
PLOS Neglected Tropical Diseases
Mooney, JP;Lee, SJ;Lokken, KL;Nanton, MR;Nuccio, SP;McSorley, SJ;Tsolis, RM;
2015
26366739
September 15th, 2015
United States
Department of Microbiology & Immunology, School of Medicine, University of California Davis, Davis, California, United States of America
Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner
Arthritis Research and Therapy
Cuda, CM;Misharin, AV;Khare, S;Saber, R;Tsai, F;Archer, AM;Homan, PJ;Haines, GK;Hutcheson, J;Dorfleutner, A;Budinger, GR;Stehlik, C;Perlman, H;
2015
26471282
October 16th, 2015
United States
Division of Rheumatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, 240 East Huron Street, Room M300, Chicago, IL, 60611, USA
Short telomeres initiate telomere recombination in primary and tumor cells
PLOS Genetics
Morrish, TA;Greider, CW;
2009
19180191
January 1st, 2009
United States
Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
Small-molecule nociceptin receptor agonist ameliorates mast cell activation and pain in sickle mice
Haematologica
Vang, D;Paul, JA;Nguyen, J;Tran, H;Vincent, L;Yasuda, D;Zaveri, NT;Gupta, K;
2015
26294734
December 1st, 2015
United States
Astraea Therapeutics, Mountain View, CA, USA nurulain@astraeatherapeutics.com
Ventral prostate fibrosis in the Akita mouse is associated with macrophage and fibrocyte infiltration
Journal of Diabetes Research
Lee, S;Yang, G;Mulligan, W;Gipp, J;Bushman, W;
2014
25019092
July 14th, 2014
United States
Department of Urology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53717, USA ; Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI 53717, USA
Salmonella enterica Typhimurium as a tumor-targeting immunotherapy vector
Thesis
Drees, J;
2015
How serotonin system alterations influence emotion-and cognition-related behaviors
Thesis
Gilman, TL;
2013
Neuron to microglia communication; a study of CX3CL1 signaling implications in cognitive function, inflammation, and neurodegeneration
Thesis
Morganti, JM;
2012
Investigation of the functional and structural role of podosomes in megakaryocytes
Thesis
Schachtner, H;
2013
Role of -Glucuronidase in the Chemopreventive Efficacy of Oral Curcumin: A Prodrug Hypothesis
Thesis
Liu, G;
2015
The Role of the Dopamine D1 Receptor in Cognition
Thesis
Arola, A;
2013
Affiliation Unavailable
Role of Astrocytes in Ischemic Preconditioning-Induced Neuroprotection
Thesis
Narayanan, S;
2015
Functional characterisation of driver events in ovarian clear cell carcinoma
Thesis
Gounaris, I;
2014
Defining the role of Notch Signalling in Intrahepatic Cholangiocarcinoma
Thesis
Guest, RV;
2015
Neuronal cicuits and reinforcement mechanisms underlying feeding behaviour
Thesis
Huang Cao, ZF;
2015
Regulation of striatal medium spiny neuron GABAA receptor mediated tonic current
Thesis
Janssen Schroeder, MJ;
2010
United States
COMBINATION IMMUNOTHERAPY TARGETING IMMUNOSUPPRESSIVE SIGNALS IN THE TUMOR MICROENVIRONMENT PREVENTS CANCER PROGRESSION
Thesis
Keenan, BP;
2015
Serotonergic Modulation of Glutamate Transmission: Bridging Two Theories of Depression
Thesis
Kallarackal, AJ;
2011
United States
THE ROLE OF PPAR- IN TROPHOBLAST LAYER DYNAMICS
Thesis
Levytska, K;
2013
Canada
Laboratory Medicine and Pathobiology,University of Toronto
Defining the functional role of laminin isoforms in the regulation of the adult hepatic progenitor cell
Thesis
Williams, MJ;
2015
More than a License to Kill: Immune Regulation of Crohn's Disease by Natural Killer Cell and Its Clinical Implication
Thesis
Lin, L;
2013
United States
University of California LA
Assessment of hepatic micronutrient disruption and the hepatotoxicity of 3, 3', 4, 4', 5-pentachlorobiphenyl (PCB126)
Thesis
Klaren, WD;
2016
Neuropilin-2 in pancreatic cancer and Semaphorin-3F as a treatment
Thesis
Li, X;
2016
Cannabinoid CB1R Receptor Mediates Metabolic Syndrome in Models of Circadian and Glucocorticoid Dysregulation
Thesis
Bowles, N;
2013
The role of Netrin-1 in semicircular canal morphogenesis
Thesis
Nishitani, A;
2014
The Role of Serotonin in the Development of Psychiatric Disorders: Studies on Drug Dependence and Anxiety-like Behaviour Following the Genetic Reduction of the
Thesis
Oakly, A;
2015
Victoria University of Wellington
Examining and improving the chemopreventive efficacy of curcumin
Thesis
Grill, AE;
2012
RON Over-expression Induces Acinar-Ductal Metaplasia and Accelerates Tumorigenesis in a Kras Mutant Mouse Model of Pancreatic Cancer
Thesis
Harper, MM;
2013
United States
UC San Diego
Study of functions of shelterins and telomerase in aging and nuclear reprograming
Thesis
Garrobo Calleja, I;
2014
Universidad AutÌ_noma de Madrid, Facultad de Ciencias, Departamento de BiologÌ_a Molecular
The role of FGFR3 mutation in tumour initiation, progression and invasion of urothelial cell carcinoma in mice
Thesis
Foth, M;
2014
Requirement for fibroblast growth factor receptor 1 in hematopoietic stem cells under stress but not during homeostasis
Thesis
Ross, JT;
2010
The Mechanism of Neuroprotection Mediated By Nicotinamide Mononucleotide Adenylyl Transferase (NMNAT)
Thesis
Ali, YO;
2011
Investigating the role of caspase cleavage of ROCK1 in tissue homeostasis and tumour development
Thesis
Julian, L;
2015
The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming
Stem Cell Reports
Unternaehrer, JJ;Zhao, R;Kim, K;Cesana, M;Powers, JT;Ratanasirintrawoot, S;Onder, T;Shibue, T;Weinberg, RA;Daley, GQ;
2014
25316190
November 11th, 2014
United States
Division of Pediatric Hematology/Oncology, Stem Cell Transplantation Program, Manton Center for Orphan Disease Research, Howard Hughes Medical Institute, Children's Hospital Boston and Dana Farber Cancer Institute, Harvard University, Cambridge, MA 02138, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Harvard University, Cambridge, MA 02138, USA; Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA
Investigating downstream effectors of KRas signalling in vivo: Dusp6 and Fra1
Thesis
Moreaux, G;
2012
In vivo characterization of pituitary adenylate cyclase-activating polypeptide in mouse olfactory epithelium
Thesis
Stamm, ML;
2011
Kiss 1 neurons and metabolic sensing
Thesis
Qiu, X;
2013
Sex differences in the cardiac beta-adrenergic receptor contractile response
Thesis
Mcintosh, V;
2012
Nutraceutical Antioxidants and Their Therapeutic Potential in Neurodegeneration
Thesis
Ross, EK;
2012
AN INVESTIGATION INTO THE ROLE OF IRON, COPPER, AND GENDER IN A TRANSGENIC MOUSE MODEL OF ALZHEIMER'S DISEASE.
Thesis
Groeber, CM;
2013
Host cell factors involved in retrovirus replication and disease pathogenesis
Thesis
Seidel, SB;
2012
United States
University of California San Diego
The mechanisms of reversal of refractory dysplasia in the salivary gland: Testing the role of p53, RXR and PPARgamma agonists, and PD0332991
Thesis
Cabrera, MC;
2012
United States
Modulation of oncogenic transformation by Raf proteins
Thesis
Karreth, F;
2009
Universitat WIEN
The Effects of Specialized Proresolving Lipid Mediators on B Lymphocyte Function: Implications for B Cell Differentiation and Antibody Production
Thesis
Ramon, S;
2013
United States
University of RochesterRochester, New York
Mechanisms of epithelial cell cancer generation: genetic risk factors on cancer progression investigated using in vivo models and at a single cell level
Thesis
Nakles, RE;
2012
United States
p53 loss and Kras mutation in an invasive murine model of colorectal cancer
Thesis
Cuesta Garcia, N;
2013
Mechanisms that control the growth of cells in the presence of replication stress
Thesis
Monasor Pascual, A;
2013
Spain
UNIVERSIDAD DE ALCALÃŒÂ, Facultad de Medicina y Ciencias de la Salud, Departamento de BiologÃŒ_a de Sistemas
Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice
Oncogenesis
Xiong, X;Chorzalska, A;Dubielecka, PM;White, JR;Vedvyas, Y;Hedvat, CV;Haimovitz-Friedman, A;Koutcher, JA;Reimand, J;Bader, GD;Sawicki, JA;Kotula, L;
2012
23552839
September 3rd, 2012
United States
Laboratory of Cell Signaling, New York Blood Center, New York, NY, USA
Regulation of DMD pathology by an ankyrin-encoded miRNA
Skeletal Muscle
Alexander, MS;Casar, JC;Motohashi, N;Myers, JA;Eisenberg, I;Gonzalez, RT;Estrella, EA;Kang, PB;Kawahara, G;Kunkel, LM;
2011
21824387
August 8th, 2011
United States
Program in Genomics and Division of Genetics, Children's Hospital Boston, 3 Blackfan Circle, CLS15024, Boston, MA 02115, USA
CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State
Stem Cell Reports
Zheng, X;Yang, P;Lackford, B;Bennett, BD;Wang, L;Li, H;Wang, Y;Miao, Y;Foley, JF;Fargo, DC;Jin, Y;Williams, CJ;Jothi, R;Hu, G;
2016
27746116
November 8th, 2016
United States
Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Pericyte structure and distribution in the cerebral cortex revealed by high-resolution imaging of transgenic mice
Neurophotonics
Hartmann, DA;Underly, RG;Grant, RI;Watson, AN;Lindner, V;Shih, AY;
2015
26158016
October 1st, 2015
United States
Medical University of South Carolina , Department of Neurosciences, 173 Ashley Avenue CRI 406, Charleston, South Carolina 29425, United States ; Medical University of South Carolina , Center for Biomedical Imaging, 68 President Street, Charleston, South Carolina 29425, United States
Transcription factor activator protein 2C and downstream redox biology effectors in development and carcinogenesis
Thesis
Cyr, AR;
2014
Crosstalk between the canonical NF-B and Notch signaling pathways inhibits Ppar expression and promotes pancreatic cancer progression in mice
The Journal of Clinical Investigation‰
Maniati, E;Bossard, M;Cook, N;Candido, JB;Emami-Shahri, N;Nedospasov, SA;Balkwill, FR;Tuveson, DA;Hagemann, T;
2011
December 6th, 2011
United Kindom
1Centre for Cancer and Inflammation, Barts Cancer Institute, Queen Mary University of London
Altered AIB1 or AIB13 expression impacts ER effects on mammary gland stromal and epithelial content
Molecular Endocrinology
Nakles, RE;Shiffert, MT;DÌ_az-Cruz, ES;Cabrera, MC;Alotaiby, M;Miermont, AM;Riegel, AT;Furth, PA;
2011
February 3rd, 2011
United States
Georgetown University, Room E520A, Research Building, 3970 Reservoir Road Northwest, Washington, D.C. 20057
Diphtheria toxin-mediated ablation of lymphatic endothelial cells results in progressive lymphedema
JCI Insight
Gardenier, JC;Hespe, GE;Kataru, RP;Savetsky, IL;Torrisi, JS;Nores, GD;Dayan, JJ;Chang, D;Zampell, J;MartÌ_nez-Corral, I;Ortega, S;Mehrara, BJ;
2016
27699240
September 22nd, 2016
United States
Section of Plastic and Reconstructive Surgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA
Role of the Regulator of G protein Signaling 4 in renal ischemic reperfusion injury and repair
Thesis
Pang, PD;
2013
Mapping Functional Brain Activation Using [14 C]-Iodoantipyrine in Male Serotonin Transporter Knockout Mice
PLOS ONE
Pang, RD;Wang, Z;Klosinski, LP;Guo, Y;Herman, DH;Celikel, T;Dong, HW;Holschneider, DP;
2011
August 23rd, 2011
United States
Graduate Program in Neuroscience, University of Southern California
Reduction in hSOD1 copy number significantly impacts ALS phenotype presentation in G37R (line 29) mice: implications for the assessment of putative therapeutic agents
Journal of Negative Results in Biomedicine
Zwiegers, P;Lee, G;Shaw, CA;
2014
25103619
August 8th, 2014
United States
Program in Experimental Medicine, University of British Columbia, Vancouver, Canada
Biosynthesis of the major brain gangliosides GD1a and GT1b
Glycobiology
Sturgill, ER;Aoki, K;Lopez, PH;Colacurcio, D;Vajn, K;Lorenzini, I;ۈ , SM;Yang, WH;Heffer, M;Tiemeyer, M;Marth, JD;Schnaar, RL;
2012
June 26th, 2012
United States
Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, 725 N. Wolfe Street, Baltimore, MD 21205, USA
The Role of Dietary Copper and Zinc on Inflammation and Oxidative Stress in Alzheimer's Disease
Thesis
Boggs, K;
2015
An Investigation into the Role of Copper Deficiency and Zinc in a Mouse Model of Early Onset Alzheimer's Disease.
Thesis
Howell, SN;
2014
SELECTIVE MOLECULAR MODIFICATION TO CALCIUM CONDUCTANCE DOMAINS OF NMDA RECEPTOR GLUN2 SUBUNITS REGULATES MATURATION OF
Thesis
Sanders, EM;
2014
United States
George Mason University
The role of neuropilin 2 in physiological and pathological angiogenesis
Thesis
Levonyak, NS;
2013
Genome wide gene expression analysis of two ENU mouse models of major mental illness
Thesis
Brown, SM;
2011
Identification of a maleimide-based glycogen synthase kinase-3 (GSK-3) inhibitor, BIP-135, that prolongs the median survival time of 7 SMA KO mouse model of
ACS Chemical Neuroscience
Chen, PC;Gaisina, IN;El-Khodor, BF;Ramboz, S;Makhortova, NR;Rubin, LL;Kozikowski, AP;
2011
October 18th, 2011
United States
Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, United States
Receptor-Dependent Phagocytosis of Clostridium sordellii by Human Decidual Macrophages
Thesis
Thelen, TD;
2010
Contribution of Organic Cation Transporter 2 (OCT2) to CisplatinInduced Nephrotoxicity
Clinical Pharmacology & Therapeutics
Filipski, KK;Mathijssen, RH;Mikkelsen, TS;Schinkel, AH;Sparreboom, A;
2009
July 22nd, 2009
United States
Department of Pharmaceutical Sciences, St Jude Children's Research Hospital,262 Danny Thomas Place Memphis, TN 38105-3678 USA
Synaptic molecular imaging in spared and deprived columns of mouse barrel cortex with array tomography
Scientific Data
Weiler, NC;Collman, F;Vogelstein, JT;Burns, R;Smith, SJ;
2014
25977797
May 15th, 2014
United States
Graduate Program in Neurosciences, Stanford University School of Medicine , Stanford, California 94305, USA ; Department of Molecular and Cellular Physiology, Stanford University School of Medicine , Stanford, California 94305, USA
Genetic Pharmacotherapy as an Early CNS Drug Development Strategy: Testing Glutaminase Inhibition for Schizophrenia Treatment in Adult Mice
Frontiers in Systems Neuroscience
Mingote, S;Masson, J;Gellman, C;Thomsen, GM;Lin, CS;Merker, RJ;Gaisler-Salomon, I;Wang, Y;Ernst, R;Hen, R;Rayport, S;
2015
26778975
January 18th, 2015
United States
Department of Psychiatry, Columbia UniversityNew York, NY, USA; Department of Molecular Therapeutics, New York State Psychiatric InstituteNew York, NY, USA
Novel tubulin and tau neuroprotective fragments sharing structural similarities with the drug candidate NAP (Davuentide)
Journal of Alzheimers Disease
Gozes, I;Iram, T;Maryanovsky, E;Arviv, C;Rozenberg, L;Schirer, Y;Giladi, E;Furman-Assaf, S;
2014
24503616
May 28th, 2014
Israel
The Adams Super Center for Brain Studies and Sagol School of Neuroscience; The Lily and Avraham Gildor Chair for the Investigation of Growth Factors, The Dr. Diana and Zelman Elton (Elbaum) Laboratory for Neuroendocrinology, Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel