Category: jci insight
Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells
Nature
Abraham, SA;Hopcroft, LE;Carrick, E;Drotar, ME;Dunn, K;Williamson, AJ;Korfi, K;Baquero, P;Park, LE;Scott, MT;Pellicano, F;Pierce, A;Copland, M;Nourse, C;Grimmond, SM;Vetrie, D;Whetton, AD;Holyoake, TL;
2016
27281222
June 8th, 2016
United Kingdom
Paul O'Gorman Leukaemia Research Centre, Institute of Cancer Sciences, University of Glasgow, Gartnavel General Hospital, 1053 Great Western Road, Glasgow G12 0YN, UK
Real-time in vivo imaging reveals localised Nrf2 stress responses associated with direct and metabolism-dependent drug toxicity
Scientific Reports
Forootan, SS;Mutter, FE;Kipar, A;Iwawaki, T;Francis, B;Goldring, CE;Park, BK;Copple, IM;
2017
29167567
November 22nd, 2017
United Kingdom
MRC Centre for Drug Safety Science, Department of Molecular and Clinical Pharmacology, Institute of Translational Medicine, University of Liverpool, Liverpool, L69 3GE, UK
Ischemic Preconditioning Protects Astrocytes against Oxygen Glucose Deprivation Via the Nuclear Erythroid 2-Related Factor 2 Pathway
Translational Stroke Research
Narayanan, SV;Dave, KR;Perez-Pinzon, MA;
2017
29103101
November 4th, 2017
United States
Cerebral Vascular Disease Research Laboratories, School of Medicine, University of Miami Miller, Miami, FL, USA
Biomechanical forces promote embryonic haematopoiesis
Nature
Adamo, L;Naveiras, O;Wenzel, PL;McKinney-Freeman, S;Mack, PJ;Gracia-Sancho, J;Suchy-Dicey, A;Yoshimoto, M;Lensch, MW;Yoder, MC;GarcÌ_a-Carde̱a, G;Daley, GQ;
2009
19440194
June 25th, 2009
United States
Center for Excellence in Vascular Biology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
RAS and RHO families of GTPases directly regulate distinct phosphoinositide 3-kinase isoforms - Cell
RAS and RHO families of GTPases directly regulate distinct phosphoinositide 3-kinase isoforms
Cell
Fritsch, R;de Krijger, I;Fritsch, K;George, R;Reason, B;Kumar, MS;Diefenbacher, M;Stamp, G;Downward, J;
2013
23706742
May 23rd, 2013
United Kingdom
Signal Transduction Laboratory, Cancer Research UK London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3LY, UK
Hunger states switch a flip-flop memory circuit via a synaptic AMPK-dependent positive feedback loop
Cell
Yang, Y;Atasoy, D;Su, HH;Sternson, SM;
2011
21925320
September 16th, 2011
United States
Janelia Farm Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA
Genetic tracing via DNGR-1 expression history defines dendritic cells as a hematopoietic lineage
Cell
Schraml, BU;van Blijswijk, J;Zelenay, S;Whitney, PG;Filby, A;Acton, SE;Rogers, NC;Moncaut, N;Carvajal, JJ;Reis e Sousa, C;
2013
23953115
August 15th, 2013
United States
Immunobiology Laboratory, Cancer Research UK, London Research Institute, Lincoln's Inn Fields Laboratories, 44 Lincoln's Inn Fields, London WC2A 3LY, UK
The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-ë_ locus
Cell
Gomez, JA;Wapinski, OL;Yang, YW;Bureau, JF;Gopinath, S;Monack, DM;Chang, HY;Brahic, M;Kirkegaard, K;
2013
23415224
February 14th, 2013
United States
Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305, USA
The retinoblastoma binding protein RBP2 is an H3K4 demethylase
Cell
Klose, RJ;Yan, Q;Tothova, Z;Yamane, K;Erdjument-Bromage, H;Tempst, P;Gilliland, DG;Zhang, Y;Kaelin, WG;
2007
17320163
March 9th, 2007
United States
Howard Hughes Medical Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
Hijacking the neuronal NMDAR signaling circuit to promote tumor growth and invasion
Cell
Li, L;Hanahan, D;
2013
23540692
March 28th, 2013
Switzerland
Swiss Institute for Experimental Cancer Research, School of Life Science, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne 1015, Switzerland
Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML
Cell
Puram, RV;Kowalczyk, MS;de Boer, CG;Schneider, RK;Miller, PG;McConkey, M;Tothova, Z;Tejero, H;Heckl, D;JÌ_rÌ´s, M;Chen, MC;Li, H;Tamayo, A;Cowley, GS;Rozenblatt-Rosen, O;Al-Shahrour, F;Regev, A;Ebert, BL;
2016
27058663
April 1st, 2016
United States
Department of Medicine, Division of Hematology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of Harvard University and MIT, Cambridge, MA 02142, USA; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02215, USA
53BP1 regulates DSB repair using Rif1 to control 5'' end resection
Science
Zimmermann, M;Lottersberger, F;Buonomo, SB;Sfeir, A;de Lange, T;
2013
23306437
February 1st, 2013
United States
Laboratory for Cell Biology and Genetics, Rockefeller University, New York, NY 10065, USA
Thalamic miR-338-3p mediates auditory thalamocortical disruption and its late onset in models of 22q11.2 microdeletion
Nature Medicine
Chun, S;Du, F;Westmoreland, JJ;Han, SB;Wang, YD;Eddins, D;Bayazitov, IT;Devaraju, P;Yu, J;Mellado Lagarde, MM;Anderson, K;Zakharenko, SS;
2016
27892953
November 28th, 2016
United States
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee, USA
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses
Nature Medicine
Moynihan, KD;Opel, CF;Szeto, GL;Tzeng, A;Zhu, EF;Engreitz, JM;Williams, RT;Rakhra, K;Zhang, MH;Rothschilds, AM;Kumari, S;Kelly, RL;Kwan, BH;Abraham, W;Hu, K;Mehta, NK;Kauke, MJ;Suh, H;Cochran, JR;Lauffenburger, DA;Wittrup, KD;Irvine, DJ;
2016
27775706
December 1st, 2016
United States
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology (MIT), Cambridge, Massachusetts, USA
Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma
Nature Medicine
Ambrogio, C;GÃŒ_mez-LÃŒ_pez, G;Falcone, M;Vidal, A;Nadal, E;Crosetto, N;Blasco, RB;FernÃŒÃndez-Marcos, PJ;SÃŒÃnchez-CÌ©spedes, M;Ren, X;Wang, Z;Ding, K;Hidalgo, M;Serrano, M;Villanueva, A;SantamarÃŒ_a, D;Barbacid, M;
2016
26855149
March 1st, 2016
Spain
Experimental Oncology, Molecular Oncology Programme, Centro Nacional de Investigaciones OncolÌ_gicas (CNIO), Madrid, Spain
Loss of BAP1 function leads to EZH2-dependent transformation
Nature Medicine
LaFave, LM;BÌ©guelin, W;Koche, R;Teater, M;Spitzer, B;Chramiec, A;Papalexi, E;Keller, MD;Hricik, T;Konstantinoff, K;Micol, JB;Durham, B;Knutson, SK;Campbell, JE;Blum, G;Shi, X;Doud, EH;Krivtsov, AV;Chung, YR;Khodos, I;de Stanchina, E;Ouerfelli, O;Adusumilli, PS;Thomas, PM;Kelleher, NL;Luo, M;Keilhack, H;Abdel-Wahab, O;Melnick, A;Armstrong, SA;Levine, RL;
2015
26437366
November 1st, 2015
United States
Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, New York, USA
Epidermal growth factor regulates hematopoietic regeneration after radiation injury
Nature Medicine
Doan, PL;Himburg, HA;Helms, K;Russell, JL;Fixsen, E;Quarmyne, M;Harris, JR;Deoliviera, D;Sullivan, JM;Chao, NJ;Kirsch, DG;Chute, JP;
2013
23377280
March 1st, 2013
United States
Department of Medicine, Division of Hematologic Malignancies and Cellular Therapy, Durham, North Carolina, USA
DNA sequencing: generation next-next
Nature Methods
Blow, N;
2008
March 15th, 2008
United States
The Editor of Nature Methods, One New York Plaza, Suite 4500,New York, NY 10004-1562, USA
IL-37 requires the receptors IL-18Rë± and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
Nature Immunology
Nold-Petry, CA;Lo, CY;Rudloff, I;Elgass, KD;Li, S;Gantier, MP;Lotz-Havla, AS;Gersting, SW;Cho, SX;Lao, JC;Ellisdon, AM;Rotter, B;Azam, T;Mangan, NE;Rossello, FJ;Whisstock, JC;Bufler, P;Garlanda, C;Mantovani, A;Dinarello, CA;Nold, MF;
2015
25729923
April 1st, 2015
Australia
1] Ritchie Centre, MIMR-PHI Institute of Medical Research, Melbourne, Victoria, Australia. [2] Department of Paediatrics, Monash University, Melbourne, Australia
The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses
Nature Immunology
Khare, S;Ratsimandresy, RA;de Almeida, L;Cuda, CM;Rellick, SL;Misharin, AV;Wallin, MC;Gangopadhyay, A;Forte, E;Gottwein, E;Perlman, H;Reed, JC;Greaves, DR;Dorfleutner, A;Stehlik, C;
2014
24531343
April 1st, 2014
United States
Division of Rheumatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma
Cancer Cell
Blasco, RB;Francoz, S;SantamarÌ_a, D;Ca̱amero, M;Dubus, P;Charron, J;Baccarini, M;Barbacid, M;
2011
21514245
May 17th, 2011
Spain
Molecular Oncology, Centro Nacional de Investigaciones OncolÌ_gicas (CNIO), E-28029 Madrid, Spain
The ALK(F1174L) mutation potentiates the oncogenic activity of MYCN in neuroblastoma
Cancer Cell
Berry, T;Luther, W;Bhatnagar, N;Jamin, Y;Poon, E;Sanda, T;Pei, D;Sharma, B;Vetharoy, WR;Hallsworth, A;Ahmad, Z;Barker, K;Moreau, L;Webber, H;Wang, W;Liu, Q;Perez-Atayde, A;Rodig, S;Cheung, NK;Raynaud, F;Hallberg, B;Robinson, SP;Gray, NS;Pearson, AD;Eccles, SA;Chesler, L;George, RE;
2012
22789543
July 10th, 2012
United Kingdom
Division of Clinical Studies, The Institute of Cancer Research, Sutton, Surrey SM2 5NG, UK
Calcification of multipotent prostate tumor endothelium
Cancer Cell
Dudley, AC;Khan, ZA;Shih, SC;Kang, SY;Zwaans, BM;Bischoff, J;Klagsbrun, M;
2008
18772110
September 1st, 2008
United States
Vascular Biology Program, Children's Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling
Nature Cell Biology
Sandilands, E;Serrels, B;McEwan, DG;Morton, JP;Macagno, JP;McLeod, K;Stevens, C;Brunton, VG;Langdon, WY;Vidal, M;Sansom, OJ;Dikic, I;Wilkinson, S;Frame, MC;
2011
22138575
December 4th, 2011
United Kingdom
Edinburgh Cancer Research UK Centre, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XR, UK
Suppression of microRNA activity amplifies IFN-ë_-induced macrophage activation and promotes anti-tumour immunity
Nature Cell Biology
Baer, C;Squadrito, ML;Laoui, D;Thompson, D;Hansen, SK;Kiialainen, A;Hoves, S;Ries, CH;Ooi, CH;De Palma, M;
2016
27295554
July 1st, 2016
Switzerland
Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ìäcole Polytechnique FÌ©dÌ©rale de Lausanne (EPFL), 1015åÊLausanne, Switzerland
PET imaging of leptin biodistribution and metabolism in rodents and primates
Cell Metabolism
Ceccarini, G;Flavell, RR;Butelman, ER;Synan, M;Willnow, TE;Bar-Dagan, M;Goldsmith, SJ;Kreek, MJ;Kothari, P;Vallabhajosula, S;Muir, TW;Friedman, JM;
2009
19656493
August 1st, 2009
United States
Laboratory of Molecular Genetics, Howard Hughes Medical Institute, The Rockefeller University, New York, NY 10065, USA
Imaging activity in neurons and glia with a Polr2a-based and cre-dependent GCaMP5G-IRES-tdTomato reporter mouse
Neuron
Gee, JM;Smith, NA;Fernandez, FR;Economo, MN;Brunert, D;Rothermel, M;Morris, SC;Talbot, A;Palumbos, S;Ichida, JM;Shepherd, JD;West, PJ;Wachowiak, M;Capecchi, MR;Wilcox, KS;White, JA;Tvrdik, P;
2014
25155958
September 1st, 2014
United States
Department of Bioengineering, University of Utah, Salt Lake City, UT 84112; Brain Institute, University of Utah, Salt Lake City, UT 84112
Sexual divergence in microtubule function: the novel intranasal microtubule targeting SKIP normalizes axonal transport and enhances memory
Molecular Psychiatry
Amram, N;Hacohen-Kleiman, G;Sragovich, S;Malishkevich, A;Katz, J;Touloumi, O;Lagoudaki, R;Grigoriadis, NC;Giladi, E;Yeheskel, A;Pasmanik-Chor, M;Jouroukhin, Y;Gozes, I;
2016
26782054
October 1st, 2016
Israel
Lily and Avraham Gildor Chair for the Investigation of Growth Factors; Elton Laboratory for Neuroendocrinology; Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Sagol School of Neuroscience and Adams Super Center for Brain Studies, Tel Aviv University, Tel Aviv, Israel
Identification of neurodegenerative factors using translatome-regulatory network analysis
Nature Neuroscience
Brichta, L;Shin, W;Jackson-Lewis, V;Blesa, J;Yap, EL;Walker, Z;Zhang, J;Roussarie, JP;Alvarez, MJ;Califano, A;Przedborski, S;Greengard, P;
2015
26214373
September 1st, 2015
United States
Laboratory of Molecular and Cellular Neuroscience, The Rockefeller University, New York, New York, USA
Diminished KCC2 confounds synapse specificity of LTP during senescence
Nature Neuroscience
Ferando, I;Faas, GC;Mody, I;
2016
27500406
September 1st, 2016
United States
Department of Neurology, The David Geffen School of Medicine, University of California, Los Angeles, California, USA
AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training
Nature Neuroscience
Aponte, Y;Atasoy, D;Sternson, SM;
2011
21209617
March 1st, 2011
United States
Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, Virginia, USA
Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in CCR2-/- mice: evidence for independent chemokine functions in atherogenesis
Circulation
Saederup, N;Chan, L;Lira, SA;Charo, IF;
2008
18165355
April 1st, 2008
United States
Gladstone Institute of Cardiovascular Disease, 1650 Owens St, San Francisco, CA 94158, USA
TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres
Molecular Cell
Kibe, T;Zimmermann, M;de Lange, T;
2016
26778124
January 21st, 2016
United States
Laboratory for Cell Biology and Genetics, Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
Inhibition of Tumor Growth and Metastasis in Pancreatic Cancer Models by Interference With CD44v6 Signaling
Gastroenterology
Matzke-Ogi, A;Jannasch, K;Shatirishvili, M;Fuchs, B;Chiblak, S;Morton, J;Tawk, B;Lindner, T;Sansom, O;Alves, F;Warth, A;Schwager, C;Mier, W;Kleeff, J;Ponta, H;Abdollahi, A;Orian-Rousseau, V;
2016
26597578
February 1st, 2016
United States
Karlsruhe Institute of Technology, Institute of Toxicology and Genetics, Eggenstein-Leopoldshafen, Germany
Ca2+ responses in enteric glia are mediated by connexin-43 hemichannels and modulate colonic transit in mice
Gastroenterology
McClain, JL;GrubiÂÃiۈ , V;Fried, D;Gomez-Suarez, RA;Leinninger, GM;SÌ©vigny, J;Parpura, V;Gulbransen, BD;
2014
24211490
February 1st, 2014
United States
Neuroscience Program and Department of Physiology, Michigan State University, East Lansing, Michigan
NOS1-derived nitric oxide promotes NF-ë¼B transcriptional activity through inhibition of suppressor of cytokine signaling-1
Journal of Experimental Medicine
Baig, MS;Zaichick, SV;Mao, M;de Abreu, AL;Bakhshi, FR;Hart, PC;Saqib, U;Deng, J;Chatterjee, S;Block, ML;Vogel, SM;Malik, AB;Consolaro, ME;Christman, JW;Minshall, RD;Gantner, BN;Bonini, MG;
2015
26324446
September 21st, 2015
United States
Department of Medicine, Department of Pharmacology, Department of Anesthesiology, and Department of Pathology, University of Illinois College of Medicine, Chicago, IL 60607 bgantner@uic.edu
Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression
Journal of Clinical Investigation
Patel, R;Gao, M;Ahmad, I;Fleming, J;Singh, LB;Rai, TS;McKie, AB;Seywright, M;Barnetson, RJ;Edwards, J;Sansom, OJ;Leung, HY;
2013
23434594
March 1st, 2013
United Kingdom
The Beatson Institute for Cancer Research, Glasgow, United Kingdom
Foxc1 and Foxc2 deletion causes abnormal lymphangiogenesis and correlates with ERK hyperactivation
Journal of Clinical Investigation
Fatima, A;Wang, Y;Uchida, Y;Norden, P;Liu, T;Culver, A;Dietz, WH;Culver, F;Millay, M;Mukouyama, YS;Kume, T;
2016
27214551
July 1st, 2016
United States
Feinberg Cardiovascular Research Institute, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA
NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth
Journal of Clinical Investigation
Jaba, IM;Zhuang, ZW;Li, N;Jiang, Y;Martin, KA;Sinusas, AJ;Papademetris, X;Simons, M;Sessa, WC;Young, LH;Tirziu, D;
2013
23454748
April 1st, 2013
United States
Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut 06510, USA
Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis
Journal of Clinical Investigation
Burstyn-Cohen, T;Heeb, MJ;Lemke, G;
2009
19729839
October 1st, 2009
United States
Molecular Neurobiology Laboratory, The Salk Institute, La Jolla, California, USA
Neurovascular crosstalk between interneurons and capillaries is required for vision
Journal of Clinical Investigation
Usui, Y;Westenskow, PD;Kurihara, T;Aguilar, E;Sakimoto, S;Paris, LP;Wittgrove, C;Feitelberg, D;Friedlander, MS;Moreno, SK;Dorrell, MI;Friedlander, M;
2015
25915585
June 1st, 2015
United States
Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, California, USA
Targeting mTOR dependency in pancreatic cancer
Gut
Morran, DC;Wu, J;Jamieson, NB;Mrowinska, A;Kalna, G;Karim, SA;Au, AY;Scarlett, CJ;Chang, DK;Pajak, MZ;, ;Oien, KA;McKay, CJ;Carter, CR;Gillen, G;Champion, S;Pimlott, SL;Anderson, KI;Evans, TR;Grimmond, SM;Biankin, AV;Sansom, OJ;Morton, JP;
2014
24717934
September 1st, 2014
United Kingdom
CRUK Beatson Institute, Glasgow, UK
Ketone bodies mediate antiseizure effects through mitochondrial permeability transition
Annals of Neurology
Kim, DY;Simeone, KA;Simeone, TA;Pandya, JD;Wilke, JC;Ahn, Y;Geddes, JW;Sullivan, PG;Rho, JM;
2015
25899847
July 1st, 2015
United States
Barrow Neurological Institute, St Joseph's Hospital and Medical Center, Phoenix, AZ
Matrix metalloproteinase 3 deletion preserves denervated motor endplates after traumatic nerve injury
Annals of Neurology
Chao, T;Frump, D;Lin, M;Caiozzo, VJ;Mozaffar, T;Steward, O;Gupta, R;
2013
23281061
February 1st, 2013
United States
Department of Orthopaedic Surgery, University of California, Irvine, Irvine, CA, USA
Periostin is required for maximal airways inflammation andåÊhyperresponsiveness in mice
Journal of Allergy and Clinical Immunology
Bentley, JK;Chen, Q;Hong, JY;Popova, AP;Lei, J;Moore, BB;Hershenson, MB;
2014
24996263
December 1st, 2014
United States
Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Mich; Department of Molecular and Integrative Physiology, University of Michigan Medical School, Ann Arbor, Mich
Endothelial cell-dependent regulation of arteriogenesis
Circulation Research
Moraes, F;Paye, J;Mac Gabhann, F;Zhuang, ZW;Zhang, J;Lanahan, AA;Simons, M;
2013
23897694
October 12th, 2013
United States
From the Department of Internal Medicine, Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, New Haven, CT
Biallelic Mutations in PDE10A Lead to Loss of Striatal PDE10A and a Hyperkinetic Movement Disorder with Onset in Infancy
American Journal of Human Genetics
Diggle, CP;Sukoff Rizzo, SJ;Popiolek, M;Hinttala, R;SchÌ_lke, JP;Kurian, MA;Carr, IM;Markham, AF;Bonthron, DT;Watson, C;Sharif, SM;Reinhart, V;James, LC;Vanase-Frawley, MA;Charych, E;Allen, M;Harms, J;Schmidt, CJ;Ng, J;Pysden, K;Strick, C;Vieira, P;Mankinen, K;Kokkonen, H;Kallioinen, M;Sormunen, R;Rinne, JO;Johansson, J;Alakurtti, K;Huilaja, L;Hurskainen, T;Tasanen, K;Anttila, E;Marques, TR;Howes, O;Politis, M;Fahiminiya, S;Nguyen, KQ;Majewski, J;Uusimaa, J;Sheridan, E;Brandon, NJ;
2016
27058446
April 7th, 2016
Finland
PEDEGO Research Unit and Medical Research Center Oulu, University of Oulu and Oulu University Hospital, PO Box 5000, 90014 Oulu, Finland; Department of Children and Adolescents, Oulu University Hospital, PO Box 23, 90029 Oulu, Finland; Biocenter Oulu, University of Oulu, PO Box 5000, 90014 Oulu, Finland
Transduction of group I mGluR-mediated synaptic plasticity by ë_-arrestin2 signalling
Nature Communications
Eng, AG;Kelver, DA;Hedrick, TP;Swanson, GT;
2016
27886171
November 25th, 2016
United States
Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa
Nature Communications
Chung, JJ;Navarro, B;Krapivinsky, G;Krapivinsky, L;Clapham, DE;
2011
21224844
January 11th, 2011
United States
1] Howard Hughes Medical Institute, Manton Center for Orphan Disease, Children's Hospital, Boston, Massachusetts 02115, USA.. [2] Department of Neurobiology, Harvard Medical School, Enders 1309, 320 Longwood Avenue, Boston, Massachusetts 02115, USA
P-Rex1 is required for efficient melanoblast migration and melanoma metastasis
Nature Communications
Lindsay, CR;Lawn, S;Campbell, AD;Faller, WJ;Rambow, F;Mort, RL;Timpson, P;Li, A;Cammareri, P;Ridgway, RA;Morton, JP;Doyle, B;Hegarty, S;Rafferty, M;Murphy, IG;McDermott, EW;Sheahan, K;Pedone, K;Finn, AJ;Groben, PA;Thomas, NE;Hao, H;Carson, C;Norman, JC;Machesky, LM;Gallagher, WM;Jackson, IJ;Van Kempen, L;Beermann, F;Der, C;Larue, L;Welch, HC;Ozanne, BW;Sansom, OJ;
2011
22109529
November 22nd, 2011
United Kingdom
The Beatson Institute for Cancer Research, Glasgow G61 1BD, UK
Inflammation-driven carcinogenesis is mediated through STING
Nature Communications
Ahn, J;Xia, T;Konno, H;Konno, K;Ruiz, P;Barber, GN;
2014
25300616
October 10th, 2014
United States
Department of Cell Biology and Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, Florida 33136, USA
Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia
Developmental Cell
Scholl, FA;Dumesic, PA;Barragan, DI;Harada, K;Bissonauth, V;Charron, J;Khavari, PA;
2007
17419998
April 1st, 2007
United States
Veterans Affairs Palo Alto Healthcare System, Palo Alto, CA 94304, USA
Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits
Developmental Cell
Ferguson, SM;Ferguson, S;Raimondi, A;Paradise, S;Shen, H;Mesaki, K;Ferguson, A;Destaing, O;Ko, G;Takasaki, J;Cremona, O;O' Toole, E;De Camilli, P;
2009
20059951
December 1st, 2009
United States
Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06510, USA
TRPC6 channel translocation into phagosomal membrane augments phagosomal function
Proceedings of the National Academy of Sciences of the United States of America
Riazanski, V;Gabdoulkhakova, AG;Boynton, LS;Eguchi, RR;Deriy, LV;Hogarth, DK;LoaÌÇc, N;Oumata, N;Galons, H;Brown, ME;Shevchenko, P;Gallan, AJ;Yoo, SG;Naren, AP;Villereal, ML;Beacham, DW;Bindokas, VP;Birnbaumer, L;Meijer, L;Nelson, DJ;
2015
26604306
November 24th, 2015
United States
Laboratory of Neurobiology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 nelson@uchicago.edu
Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity
Proceedings of the National Academy of Sciences of the United States of America
Sah, R;Mesirca, P;Van den Boogert, M;Rosen, J;Mably, J;Mangoni, ME;Clapham, DE;
2013
23878236
August 1st, 2013
United States
Howard Hughes Medical Institute, Department of Cardiology, Boston Children's Hospital, Boston, MA 02115, USA
Notch3 drives development and progression of cholangiocarcinoma
Proceedings of the National Academy of Sciences of the United States of America
Guest, RV;Boulter, L;Dwyer, BJ;Kendall, TJ;Man, TY;Minnis-Lyons, SE;Lu, WY;Robson, AJ;Gonzalez, SF;Raven, A;Wojtacha, D;Morton, JP;Komuta, M;Roskams, T;Wigmore, SJ;Sansom, OJ;Forbes, SJ;
2016
27791012
October 25th, 2016
United Kingdom
Medical Research Council Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4UU, United Kingdom; Department of Surgery, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, United Kingdom; stuart.forbes@ed.ac.uk
Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer
Proceedings of the National Academy of Sciences of the United States of America
Ahmad, I;Mui, E;Galbraith, L;Patel, R;Tan, EH;Salji, M;Rust, AG;Repiscak, P;Hedley, A;Markert, E;Loveridge, C;van der Weyden, L;Edwards, J;Sansom, OJ;Adams, DJ;Leung, HY;
2016
27357679
July 19th, 2016
United Kingdom
Cancer Research UK Beatson Institute, Bearsden, Glasgow G61 1BD, United Kingdom; Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, United Kingdom; h.leung@beatson.gla.ac.uk
Striosome-dendron bouquets highlight a unique striatonigral circuit targeting dopamine-containing neurons
Proceedings of the National Academy of Sciences of the United States of America
Crittenden, JR;Tillberg, PW;Riad, MH;Shima, Y;Gerfen, CR;Curry, J;Housman, DE;Nelson, SB;Boyden, ES;Graybiel, AM;
2016
27647894
October 4th, 2016
United States
McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139
Identification of cancer initiating cells in K-Ras driven lung adenocarcinoma
Proceedings of the National Academy of Sciences of the United States of America
Mainardi, S;Mijimolle, N;Francoz, S;Vicente-Due̱as, C;SÃŒÃnchez-GarcÃŒ_a, I;Barbacid, M;
2014
24367082
January 1st, 2014
Spain
Molecular Oncology Programme, Centro Nacional de Investigaciones OncolÌ_gicas, 28029 Madrid, Spain
Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation
Proceedings of the National Academy of Sciences of the United States of America
Castillo, EF;Dekonenko, A;Arko-Mensah, J;Mandell, MA;Dupont, N;Jiang, S;Delgado-Vargas, M;Timmins, GS;Bhattacharya, D;Yang, H;Hutt, J;Lyons, CR;Dobos, KM;Deretic, V;
2012
23093667
November 13th, 2012
United States
Department of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA
HER2 overcomes PTEN (loss)-induced senescence to cause aggressive prostate cancer
Proceedings of the National Academy of Sciences of the United States of America
Ahmad, I;Patel, R;Singh, LB;Nixon, C;Seywright, M;Barnetson, RJ;Brunton, VG;Muller, WJ;Edwards, J;Sansom, OJ;Leung, HY;
2011
21930937
September 27th, 2011
United Kingdom
Beatson Institute for Cancer Research, Glasgow G61 1BD, United Kingdom
Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice
Proceedings of the National Academy of Sciences of the United States of America
Laposa, RR;Huang, EJ;Cleaver, JE;
2007
17229834
January 23rd, 2007
United States
Department of Dermatology and Cancer Center, University of California, San Francisco, CA 94143-0808, USA
Cystic fibrosis transmembrane conductance regulator with a shortened R domain rescues the intestinal phenotype of CFTR-/- mice
Proceedings of the National Academy of Sciences of the United States of America
Ostedgaard, LS;Meyerholz, DK;Vermeer, DW;Karp, PH;Schneider, L;Sigmund, CD;Welsh, MJ;
2011
21285372
February 15th, 2011
United States
Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
The preproghrelin gene is required for the normal integration of thermoregulation and sleep in mice
Proceedings of the National Academy of Sciences of the United States of America
Szentirmai, E;KapÃŒÃs, L;Sun, Y;Smith, RG;Krueger, JM;
2009
19666521
August 18th, 2009
United States
Sleep and Performance Research Center, Department of Veterinary and Comparative Anatomy, Pharmacology, and Physiology, Washington State University, Pullman, WA 99164, USA
CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo
Proceedings of the National Academy of Sciences of the United States of America
Zhu, JG;Ochalek, JT;Kaufmann, M;Jones, G;Deluca, HF;
2013
24019477
September 24th, 2013
United States
Department of Biochemistry, University of Wisconsin, Madison, WI 53706
STING manifests self DNA-dependent inflammatory disease
Proceedings of the National Academy of Sciences of the United States of America
Ahn, J;Gutman, D;Saijo, S;Barber, GN;
2012
23132945
November 20th, 2012
United States
Department of Cell Biology and Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, FL 33136, USA
A human IL10 BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome
Proceedings of the National Academy of Sciences of the United States of America
Ranatunga, D;Hedrich, CM;Wang, F;McVicar, DW;Nowak, N;Joshi, T;Feigenbaum, L;Grant, LR;StÌ_ger, S;Bream, JH;
2009
19805095
October 1st, 2009
United States
W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205-1901, USA
Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst
Proceedings of the National Academy of Sciences of the United States of America
Ramsey, IS;Ruchti, E;Kaczmarek, JS;Clapham, DE;
2009
19372380
May 1st, 2009
United States
Howard Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, and Department of Cardiovascular Research, Manton Center for Orphan Disease, Children's Hospital, 320 Longwood Avenue, Boston, MA 02115, USA
Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine ë_-thalassemia
Blood
Suragani, RN;Cawley, SM;Li, R;Wallner, S;Alexander, MJ;Mulivor, AW;Gardenghi, S;Rivella, S;Grinberg, AV;Pearsall, RS;Kumar, R;
2014
24795345
June 19th, 2014
United States
Acceleron Pharma, Cambridge, MA; and
FGF signaling facilitates postinjury recovery of mouse hematopoietic system
Blood
Zhao, M;Ross, JT;Itkin, T;Perry, JM;Venkatraman, A;Haug, JS;Hembree, MJ;Deng, CX;Lapidot, T;He, XC;Li, L;
2012
22802336
August 30th, 2012
United States
Stowers Institute for Medical Research, Kansas City, MO 64110, USA
Targeting vasculogenesis to prevent progression in multiple myeloma
Leukemia
Moschetta, M;Mishima, Y;Kawano, Y;Manier, S;Paiva, B;Palomera, L;Aljawai, Y;Calcinotto, A;Unitt, C;Sahin, I;Sacco, A;Glavey, S;Shi, J;Reagan, MR;Prosper, F;Bellone, M;Chesi, M;Bergsagel, LP;Vacca, A;Roccaro, AM;Ghobrial, IM;
2016
26859080
May 1st, 2016
United States
Medical Oncology, Harvard Medical School, Dana-Farber Cancer Institute, Boston, MA, USA
p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia
Cancer Research
Hendley, AM;Wang, YJ;Polireddy, K;Alsina, J;Ahmed, I;Lafaro, KJ;Zhang, H;Roy, N;Savidge, SG;Cao, Y;Hebrok, M;Maitra, A;Reynolds, AB;Goggins, M;Younes, M;Iacobuzio-Donahue, CA;Leach, SD;Bailey, JM;
2016
27032419
June 1st, 2016
United States
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland. The McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland. The David Rubenstein Pancreatic Cancer Research Center, Memorial Sloan Kettering Cancer Center, New York, New York. Jennifer.M.Bailey@uth.tmc.edu
Deregulated estrogen receptor alpha and p53 heterozygosity collaborate in the development of mammary hyperplasia
Cancer Research
DÌ_az-Cruz, ES;Furth, PA;
2010
20466998
May 15th, 2010
United States
Departments of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia 20057, USA
STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma
Cancer Research
Lau, J;Ilkhanizadeh, S;Wang, S;Miroshnikova, YA;Salvatierra, NA;Wong, RA;Schmidt, C;Weaver, VM;Weiss, WA;Persson, AI;
2015
26282165
October 15th, 2015
United States
Department of Pediatrics, University of California, San Francisco, San Francisco, California. Department of Neurology, Neurological Surgery and Brain Tumor Research Center, University of California, San Francisco, San Francisco, California. Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California. waweiss@gmail.com
Obesity promotes breast cancer by CCL2-mediated macrophage recruitment and angiogenesis
Cancer Research
Arendt, LM;McCready, J;Keller, PJ;Baker, DD;Naber, SP;Seewaldt, V;Kuperwasser, C;
2013
23959857
October 1st, 2013
United States
Authors' Affiliations: Developmental, Molecular, and Chemical Biology Department, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine; Molecular Oncology Research Institute and Medical Oncology and Department of Pathology, Tufts Medical Center, Boston, Massachusetts; and Departments of Medicine, Duke University, Durham, North Carolina
A novel mouse model that develops spontaneous arthritis and is predisposed towards atherosclerosis
Annals of Rheumatic Diseases
Rose, S;Eren, M;Murphy, S;Zhang, H;Thaxton, CS;Chowaniec, J;Waters, EA;Meade, TJ;Vaughan, DE;Perlman, H;
2013
22736097
January 1st, 2013
United States
Department of Medicine, Northwestern UniversityFeinberg School of Medicine, Chicago, IL, USA
The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis
Oncogene
Park, JM;Wu, T;Cyr, AR;Woodfield, GW;De Andrade, JP;Spanheimer, PM;Li, T;Sugg, SL;Lal, G;Domann, FE;Zhang, W;Weigel, RJ;
2015
25772240
December 10th, 2015
United States
Department of Surgery, University of Iowa, Iowa City, IA, USA
In vivo oncogenic conflict triggered by co-existing KRAS and EGFR activating mutations in lung adenocarcinoma
Oncogene
Ambrogio, C;Barbacid, M;SantamarÌ_a, D;
2016
27775074
October 24th, 2016
Spain
Experimental Oncology, Molecular Oncology Programme, Centro Nacional de Investigaciones OncolÌ_gicas (CNIO), Madrid, Spain
TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis - Oncogene
TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis
Oncogene
Cyr, AR;Kulak, MV;Park, JM;Bogachek, MV;Spanheimer, PM;Woodfield, GW;White-Baer, LS;O'Malley, YQ;Sugg, SL;Olivier, AK;Zhang, W;Domann, FE;Weigel, RJ;
2015
24469049
January 22nd, 2015
United States
1] Department of Surgery, University of Iowa, Iowa City, IA, USA [2] Department of Radiation Oncology, University of Iowa, Iowa City, IA, USA
Mek1/2 gene dosage determines tissue response to oncogenic Ras signaling in the skin
Oncogene
Scholl, FA;Dumesic, PA;Barragan, DI;Charron, J;Khavari, PA;
2009
19198628
March 26th, 2009
United States
Department of Dermatology, Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA 94305, USA
Functions of TAp63 and p53 in restraining the development of metastatic cancer
Oncogene
Tan, EH;Morton, JP;Timpson, P;Tucci, P;Melino, G;Flores, ER;Sansom, OJ;Vousden, KH;Muller, PA;
2014
23873029
June 19th, 2014
United Kingdom
Cancer Research UK Beatson Institute, Glasgow, UK
p53 mutations cooperate with oncogenic Kras to promote adenocarcinoma from pancreatic ductal cells
Oncogene
Bailey, JM;Hendley, AM;Lafaro, KJ;Pruski, MA;Jones, NC;Alsina, J;Younes, M;Maitra, A;McAllister, F;Iacobuzio-Donahue, CA;Leach, SD;
2016
26592447
August 11th, 2016
United States
Department of Internal Medicine, Division of Gastroenterology, Hepatology and Nutrition, The University of Texas Health Science Center at Houston, Houston, TX, USA
C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptor
Elife
Azevedo, AW;Doan, T;Moaven, H;Sokal, I;Baameur, F;Vishnivetskiy, SA;Homan, KT;Tesmer, JJ;Gurevich, VV;Chen, J;Rieke, F;
2015
25910054
April 24th, 2015
United States
Department of Physiology and Biophysics, University of Washington, Seattle, United States
Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel
Elife
Lana-Elola, E;Watson-Scales, S;Slender, A;Gibbins, D;Martineau, A;Douglas, C;Mohun, T;Fisher, EM;Tybulewicz, VLj;
2016
26765563
January 14th, 2016
United Kingdom
The Francis Crick Institute, London, United Kingdom
Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration
Elife
Kurihara, T;Westenskow, PD;Gantner, ML;Usui, Y;Schultz, A;Bravo, S;Aguilar, E;Wittgrove, C;Friedlander, MSh;Paris, LP;Chew, E;Siuzdak, G;Friedlander, M;
2016
26978795
March 15th, 2016
United States
Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, United States
Sex differences in cerebellar synaptic transmission and sex-specific responses to autism-linked Gabrb3 mutations in mice
Elife
Mercer, AA;Palarz, KJ;Tabatadze, N;Woolley, CS;Raman, IM;
2016
27077953
April 14th, 2016
United States
Northwestern University Interdepartmental Neuroscience Program, Northwestern University, Evanston, United States
Kindlin1 regulates microtubule function to ensure normal mitosis - Journal of Molecular Cell Biology
Kindlin1 regulates microtubule function to ensure normal mitosis
Journal of Molecular Cell Biology
Patel, H;Stavrou, I;Shrestha, RL;Draviam, V;Frame, MC;Brunton, VG;
2016
26993041
August 1st, 2016
United Kingdom
Edinburgh Cancer Research Centre, Institute of Genetics & Molecular Medicine, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK h.patel@ed.ac.uk
Matrix metalloproteinase-20 mediates dental enamel biomineralization by preventing protein occlusion inside apatite crystals
Biomaterials
Prajapati, S;Tao, J;Ruan, Q;De Yoreo, JJ;Moradian-Oldak, J;
2016
26513418
January 1st, 2016
United States
University of Southern California, Herman Ostrow School of Dentistry, Division of Biomedical Sciences, Center for Craniofacial Molecular Biology, Los Angeles, CA 90033, USA
Disrupted Cortical State Regulation in a Rat Model of Fragile X Syndrome
Cerebral Cortex
Berzhanskaya, J;Phillips, MA;Gorin, A;Lai, C;Shen, J;Colonnese, MT;
2016
26733529
January 5th, 2016
United States
Department of Pharmacology and Physiology and Institute for Neuroscienc,2300 Eye St NW, Ross Hall 640, Washington, DC 20037, USA.
Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy
EMBO Molecular Medicine
Miller, BW;Morton, JP;Pinese, M;Saturno, G;Jamieson, NB;McGhee, E;Timpson, P;Leach, J;McGarry, L;Shanks, E;Bailey, P;Chang, D;Oien, K;Karim, S;Au, A;Steele, C;Carter, CR;McKay, C;Anderson, K;Evans, TR;Marais, R;Springer, C;Biankin, A;Erler, JT;Sansom, OJ;
2015
26077591
June 15th, 2015
Denmark
Biotech Research & Innovation Centre (BRIC), University of Copenhagen, Copenhagen (UCPH), Denmark o.sansom@beatson.gla.ac.uk
SPRY2 loss enhances ErbB trafficking and PI3K/AKT signalling to drive human and mouse prostate carcinogenesis
EMBO Molecular Medicine
Gao, M;Patel, R;Ahmad, I;Fleming, J;Edwards, J;McCracken, S;Sahadevan, K;Seywright, M;Norman, J;Sansom, O;Leung, HY;
2012
22649008
August 1st, 2012
United Kingdom
Beatson Institute for Cancer Research, Glasgow, UK
p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium
EMBO Molecular Medicine
Cole, AM;Ridgway, RA;Derkits, SE;Parry, L;Barker, N;Clevers, H;Clarke, AR;Sansom, OJ;
2010
20976827
November 1st, 2010
United Kingdom
Beatson Institute of Cancer Research, Glasgow, UK
Differential role of lipocalin 2 during immune complex-mediated acute and chronic inflammation in mice
Arthritis & Rheumatology
Shashidharamurthy, R;Machiah, D;Aitken, JD;Putty, K;Srinivasan, G;Chassaing, B;Parkos, CA;Selvaraj, P;Vijay-Kumar, M;
2013
23280250
April 1st, 2013
United States
Department of Pharmaceutical Sciences, Philadelphia College of Osteopathic Medicine, Suwanee, Georgia 30024, USA
Requirement of myeloid cell-specific Fas expression for prevention of systemic autoimmunity in mice
Arthritis & Rheumatology
Cuda, CM;Agrawal, H;Misharin, AV;Haines, GK;Hutcheson, J;Weber, E;Schoenfeldt, JA;Mohan, C;Pope, RM;Perlman, H;
2012
22143975
March 1st, 2012
United States
Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Role of ë_4* Nicotinic Acetylcholine Receptors in the Habenulo-Interpeduncular Pathway in Nicotine Reinforcement in Mice
Neuropsychopharmacology
Harrington, L;Vi̱als, X;Herrera-SolÌ_s, A;Flores, A;Morel, C;Tolu, S;Faure, P;Maldonado, R;Maskos, U;Robledo, P;
2016
26585290
June 1st, 2016
Spain
Unit̩ Neurobiologie Int̩grative des Syst̬mes Cholinergiques, D̩partement de Neuroscience, Institut Pasteur, Paris Cedex, France
Forebrain-specific CRF overproduction during development is sufficient to induce enduring anxiety and startle abnormalities in adult mice
Neuropsychopharmacology
Toth, M;Gresack, JE;Bangasser, DA;Plona, Z;Valentino, RJ;Flandreau, EI;Mansuy, IM;Merlo-Pich, E;Geyer, MA;Risbrough, VB;
2014
24326400
May 1st, 2014
United States
1] Department of Psychiatry, University of California San Diego, La Jolla, CA, USA [2] Center of Excellence for Stress and Mental Health, Veterans Affairs Hospital, La Jolla, CA, USA
NADPH Oxidase-Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes
Small
Sun, B;Wang, X;Ji, Z;Wang, M;Liao, YP;Chang, CH;Li, R;Zhang, H;Nel, AE;Xia, T;
2015
25581126
May 6th, 2015
United States
Nature Methods,5,267,2008
CXCR2 inhibition suppresses acute and chronic pancreatic inflammation
Journal of Pathology
Steele, CW;Karim, SA;Foth, M;Rishi, L;Leach, JD;Porter, RJ;Nixon, C;Jeffry Evans, TR;Carter, CR;Nibbs, RJ;Sansom, OJ;Morton, JP;
2015
25950520
September 1st, 2015
United Kingdom
Cancer Research UK Beatson Institute, Glasgow, UK
Fibroblast growth factor receptor 3 activation plays a causative role in urothelial cancer pathogenesis in cooperation with Pten loss in mice
Journal of Pathology
Foth, M;Ahmad, I;van Rhijn, BW;van der Kwast, T;Bergman, AM;King, L;Ridgway, R;Leung, HY;Fraser, S;Sansom, OJ;Iwata, T;
2014
24519156
June 1st, 2014
United Kingdom
School of Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK; Beatson Institute for Cancer Research, Glasgow, UK
Vertebrate Host Susceptibility to Heartland Virus
Emerging Infectious Diseases
Lauth, AM;Calvert, AE;Root, JJ;Gidlewski, T;Bird, BH;Bowen, RA;Muehlenbachs, A;Zaki, SR;Brault, AC;
2016
December 1st, 2016
United States
Centers for Disease Control and Prevention, 3156 Rampart Rd, Foothills Campus, Fort Collins, CO 80521, USA
Telomere-Internal Double-Strand Breaks Are Repaired by Homologous Recombination and PARP1/Lig3-Dependent End-Joining
Cell Reports
Doksani, Y;de Lange, T;
2016
27806302
November 1st, 2016
European Union
Laboratory for Cell Biology and Genetics, Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
Expression of BCR/ABL p210 from a knockin allele enhances bone marrow engraftment without inducing neoplasia
Cell Reports
Foley, SB;Hildenbrand, ZL;Soyombo, AA;Magee, JA;Wu, Y;Oravecz-Wilson, KI;Ross, TS;
2013
24095735
October 17th, 2013
United States
Department of Internal Medicine and Cancer Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Role of angiopoietin-2 in adaptive tumor resistance to VEGF signaling blockade
Cell Reports
Rigamonti, N;Kadioglu, E;Keklikoglou, I;Wyser Rmili, C;Leow, CC;De Palma, M;
2014
25088418
August 1st, 2014
Switzerland
Swiss Institute for Experimental Cancer Research (ISREC), School of Life Sciences, Ìäcole Polytechnique FÌ©dÌ©rale de Lausanne (EPFL), 1015åÊLausanne, Switzerland
Pten loss in Olig2 expressing neural progenitor cells and oligodendrocytes leads to interneuron dysplasia and leukodystrophy
Stem Cells
Maire, CL;Ramkissoon, S;Hayashi, M;Haidar, S;Ramkissoon, L;DiTomaso, E;Ligon, KL;
2014
24395742
January 1st, 2014
United States
Department of Medical Oncology, Center for Molecular Oncologic Pathology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA
Target-derived neurotrophins coordinate transcription and transport of bclw to prevent axonal degeneration
Journal of Neuroscience
Cosker, KE;Pazyra-Murphy, MF;Fenstermacher, SJ;Segal, RA;
2013
23516285
March 20th, 2013
United States
Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA
Fatty Acid-Binding Protein 5 at the Blood-Brain Barrier Regulates Endogenous Brain Docosahexaenoic Acid Levels and Cognitive Function
Journal of Neuroscience
Pan, Y;Short, JL;Choy, KH;Zeng, AX;Marriott, PJ;Owada, Y;Scanlon, MJ;Porter, CJ;Nicolazzo, JA;
2016
27852782
November 16th, 2016
United States
Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia
The Angelman syndrome protein Ube3a/E6AP is required for Golgi acidification and surface protein sialylation
Journal of Neuroscience
Condon, KH;Ho, J;Robinson, CG;Hanus, C;Ehlers, MD;
2013
23447592
February 27th, 2013
United States
Department of Neurobiology, Duke University Medical Center, Durham, North Carolina 27710, USA
Homeostatic responses fail to correct defective amygdala inhibitory circuit maturation in fragile X syndrome
Journal of Neuroscience
Vislay, RL;Martin, BS;Olmos-Serrano, JL;Kratovac, S;Nelson, DL;Corbin, JG;Huntsman, MM;
2013
23616559
April 24th, 2013
United States
Center for Neuroscience Research, Children's National Medical Center, Washington, DC 20010, USA
PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons
Journal of Neuroscience
Ying, SW;Tibbs, GR;Picollo, A;Abbas, SY;Sanford, RL;Accardi, A;Hofmann, F;Ludwig, A;Goldstein, PA;
2011
21753018
July 13th, 2011
United States
Department of Anesthesiology, Weill Cornell Medical College, New York, New York 10065, USA
Mature mice lacking Rbl2/p130 gene have supernumerary inner ear hair cells and supporting cells
Journal of Neuroscience
Rocha-Sanchez, SM;Scheetz, LR;Contreras, M;Weston, MD;Korte, M;McGee, J;Walsh, EJ;
2011
21677172
June 15th, 2011
United States
Department of Oral Biology, Creighton University School of Dentistry, Omaha, Nebraska 68178, USA
The p38ë± MAPK regulates microglial responsiveness to diffuse traumatic brain injury
Journal of Neuroscience
Bachstetter, AD;Rowe, RK;Kaneko, M;Goulding, D;Lifshitz, J;Van Eldik, LJ;
2013
23554495
April 1st, 2013
United States
Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky 40536, USA
PPARë_ recruitment to active ERK during memory consolidation is required for Alzheimer''s disease-related cognitive enhancement
Journal of Neuroscience
Jahrling, JB;Hernandez, CM;Denner, L;Dineley, KT;
2014
24623782
March 12th, 2014
United States
Mitchell Center for Neurodegenerative Diseases, Departments of Neurology and Internal Medicine, Division of Endocrinology, McCoy Stem Cells and Diabetes Mass Spectrometry Research Laboratory, Sealy Center for Molecular Medicine, and Institute for Translational Science, University of Texas Medical Branch, Galveston, Texas 77555
Sensory neuropathy attributable to loss of Bcl-w
Journal of Neuroscience
Courchesne, SL;Karch, C;Pazyra-Murphy, MF;Segal, RA;
2011
21289171
February 1st, 2011
United States
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA
Circuit-specific intracortical hyperconnectivity in mice with deletion of the autism-associated Met receptor tyrosine kinase
Journal of Neuroscience
Qiu, S;Anderson, CT;Levitt, P;Shepherd, GM;
2011
21490227
April 13th, 2011
United States
Zilkha Neurogenetics Institute, Department of Cell and Neurobiology, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
Dendritic HCN2 channels constrain glutamate-driven excitability in reticular thalamic neurons
Journal of Neuroscience
Ying, SW;Jia, F;Abbas, SY;Hofmann, F;Ludwig, A;Goldstein, PA;
2007
17687049
August 1st, 2007
United States
C. V. Starr Laboratory for Molecular Neuropharmacology, Department of Anesthesiology, Weill Medical College, Cornell University, New York, New York 10021, USA
A new mouse model for stationary night blindness with mutant Slc24a1 explains the pathophysiology of the associated human disease
Human Molecular Genetics
Vinberg, F;Wang, T;Molday, RS;Chen, J;Kefalov, VJ;
2015
26246500
October 15th, 2015
United States
Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA
CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy
Human Molecular Genetics
Ljungberg, MC;Ali, YO;Zhu, J;Wu, CS;Oka, K;Zhai, RG;Lu, HC;
2012
22027994
January 15th, 2012
United States
The Cain Foundation Laboratories, Jan and Dan Duncan Neurological Research Institute at Texas Children‰Ûªs Hospital, Baylor College of Medicine, Houston, TX 77030, USA
Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis
Human Molecular Genetics
Husson, H;Moreno, S;Smith, LA;Smith, MM;Russo, RJ;Pitstick, R;Sergeev, M;Ledbetter, SR;Bukanov, NO;Lane, M;Zhang, K;Billot, K;Carlson, G;Shah, J;Meijer, L;Beier, DR;Ibraghimov-Beskrovnaya, O;
2016
27053712
June 1st, 2016
United States
Department of Rare Diseases, Sanofi-Genzyme R&D Center, 49 New York Avenue, Framingham, MA 01701, USA
Lipid-enriched diet rescues lethality and slows down progression in a murine model of VCP-associated disease
Human Molecular Genetics
Llewellyn, KJ;Nalbandian, A;Jung, KM;Nguyen, C;Avanesian, A;Mozaffar, T;Piomelli, D;Kimonis, VE;
2014
24158850
March 1st, 2014
United States
Department of Pediatrics, Division of Genetics and Metabolism
Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease
Human Molecular Genetics
Natoli, TA;Husson, H;Rogers, KA;Smith, LA;Wang, B;Budman, Y;Bukanov, NO;Ledbetter, SR;Klinger, KW;Leonard, JP;Ibraghimov-Beskrovnaya, O;
2012
22563011
August 1st, 2012
United States
Department of Cell Biology, Genzyme Corporation, Framingham, MA 01701, USA
Glycogen accumulation underlies neurodegeneration and autophagy impairment in Lafora disease
Human Molecular Genetics
Duran, J;Gruart, A;GarcÌ_a-Rocha, M;Delgado-GarcÌ_a, JM;Guinovart, JJ;
2014
24452334
June 15th, 2014
Spain
Institute for Research in Biomedicine (IRB Barcelona), Barcelona 08028, Spain Centro de InvestigaciÌ_n BiomÌ©dica en Red de Diabetes y Enfermedades MetabÌ_licas Asociadas (CIBERDEM), Barcelona 08017, Spain Department of Biochemistry and Molecular Biology, University of Barcelona, Barcelona 08028, Spain
AKT regulates NPM dependent ARF localization and p53mut stability in tumors
Oncotarget
Hamilton, G;Abraham, AG;Morton, J;Sampson, O;Pefani, DE;Khoronenkova, S;Grawenda, A;Papaspyropoulos, A;Jamieson, N;McKay, C;Sansom, O;Dianov, GL;O'Neill, E;
2014
25071014
August 15th, 2014
United Kingdom
Cancer Research UK/MRC Oxford Institute, Department of Oncology, University of Oxford, Old Road Campus, Roosevelt Drive, UK
The role of apoptosis in immune hyporesponsiveness following AAV8 liver gene transfer
Molecular Therapy
Faust, SM;Bell, P;Zhu, Y;Sanmiguel, J;Wilson, JM;
2013
24126962
December 1st, 2013
United States
Department of Pathology and Laboratory Medicine, Gene Therapy Program, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling
Journal of Investigative Dermatology
Pawlikowski, JS;Brock, C;Chen, SC;Al-Olabi, L;Nixon, C;McGregor, F;Paine, S;Chanudet, E;Lambie, W;Holmes, WM;Mullin, JM;Richmond, A;Wu, H;Blyth, K;King, A;Kinsler, VA;Adams, PD;
2015
26178707
November 1st, 2015
United Kingdom
Institute of Cancer Sciences, University of Glasgow, Glasgow, UK
ë±5 and ë±v integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo
Development
Turner, CJ;Badu-Nkansah, K;Crowley, D;van der Flier, A;Hynes, RO;
2015
25670798
February 15th, 2015
United States
Howard Hughes Medical Institute, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle
Development
Gokhin, DS;Ochala, J;Domenighetti, AA;Fowler, VM;
2015
26586224
December 15th, 2015
United States
Department of Cell and Molecular Biology, The Scripps Research Institute, La Jolla, CA 92037, USA velia@scripps.edu
Phenotypic analysis of mice completely lacking netrin 1
Development
Yung, AR;Nishitani, AM;Goodrich, LV;
2015
26395479
November 1st, 2015
United States
Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA
Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development
Development
van der Flier, A;Badu-Nkansah, K;Whittaker, CA;Crowley, D;Bronson, RT;Lacy-Hulbert, A;Hynes, RO;
2010
20570943
July 1st, 2010
United States
Howard Hughes Medical Institute, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development
Development
Mao, Y;Mulvaney, J;Zakaria, S;Yu, T;Morgan, KM;Allen, S;Basson, MA;Francis-West, P;Irvine, KD;
2011
21303848
March 1st, 2011
United Kingdom
Howard Hughes Medical Institute, Waksman Institute and Department of Molecular Biology and Biochemistry, Rutgers University, Piscataway, NJ 08854, USA
Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation
Development
Ma, Y;Li, A;Faller, WJ;Libertini, S;Fiorito, F;Gillespie, DA;Sansom, OJ;Yamashiro, S;Machesky, LM;
2013
23633513
May 1st, 2013
United Kingdom
Beatson Institute for Cancer Research, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK
The neuron-specific interleukin-1 receptor accessory protein is required for homeostatic sleep and sleep responses to influenza viral challenge in mice
Brain Behavior and Immunity
Davis, CJ;Dunbrasky, D;Oonk, M;Taishi, P;Opp, MR;Krueger, JM;
2015
25449578
July 1st, 2015
United States
College of Medical Sciences and the Sleep and Performance Research Center, Washington State University Spokane, Spokane, WA 99210, United States
Sickness behaviour after lipopolysaccharide treatment in ghrelin deficient mice
Brain Behavior and Immunity
Szentirmai, Ìä;Krueger, JM;
2014
24309634
February 1st, 2014
United States
Washington, Wyoming, Alaska, Montana and Idaho (WWAMI) Medical Education Program, Washington State University, Spokane, WA, USA; Department of Integrative Physiology and Neuroscience, Washington State University, Pullman, WA, USA; Sleep and Performance Research Center, Washington State University, Spokane, WA, USA
Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow aging
Aging Cell
Arum, O;Boparai, RK;Saleh, JK;Wang, F;Dirks, AL;Turner, JG;Kopchick, JJ;Liu, JL;Khardori, RK;Bartke, A;
2014
25244225
December 1st, 2014
United States
Department of Internal Medicine, Southern Illinois University-School of Medicine, Springfield, IL, 62794, USA
Sensitization of nociceptive spinal neurons contributes to pain in a transgenic model of sickle cell disease
Pain
Cataldo, G;Rajput, S;Gupta, K;Simone, DA;
2015
25630029
April 1st, 2015
United States
aDepartment of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN, USA bDivision of Hematology, Oncology and Transplantation, Department of Medicine, Vascular Biology Center, University of Minnesota, Minneapolis, MN, USA
Optogenetic release of norepinephrine from cardiac sympathetic neurons alters mechanical and electrical function
Cardiovascular Research
Wengrowski, AM;Wang, X;Tapa, S;Posnack, NG;Mendelowitz, D;Kay, MW;
2015
25514932
February 1st, 2015
United States
Department of Biomedical Engineering, The George Washington University, Phillips Hall, Room 607, 801 22nd Street NW, Washington, DC 20052, USA Department of Pharmacology and Physiology, The George Washington University, Washington, DC, USA
NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis
Free Radical Biology and Medicine
Di Marco, E;Gray, SP;Kennedy, K;Szyndralewiez, C;Lyle, AN;Lass̬gue, B;Griendling, KK;Cooper, ME;Schmidt, HH;Jandeleit-Dahm, KA;
2016
27445103
August 1st, 2016
Australia
Diabetic Complications Division, Baker IDI Heart & Diabetes Institute, Melbourne, Australia; Department of Medicine, Monash University, Melbourne, Australia
Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury
Free Radical Biology and Medicine
Mukhopadhyay, P;HorvÃŒÃth, B;Rajesh, M;Matsumoto, S;Saito, K;BÃŒÃtkai, S;Patel, V;Tanchian, G;Gao, RY;Cravatt, BF;HaskÃŒ_, G;Pacher, P;
2011
21070851
January 1st, 2011
United States
Laboratory of Physiologic Studies, National Institute on Alcohol Abuse and Alcoholism, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, USA
Chk1 is essential for the development of murine epidermal melanocytes
Pigment Cell and Melanoma Research
Smith, J;Larue, L;Gillespie, DA;
2013
23557358
July 1st, 2013
United Kingdom
Beatson Institute for Cancer Research, Glasgow, UK
Differential effects of NOX4 and NOX1 on immune cell-mediated inflammation in the aortic sinus of diabetic ApoE-/- mice
Clinical Science
Di Marco, E;Gray, SP;Chew, P;Kennedy, K;Cooper, ME;Schmidt, HH;Jandeleit-Dahm, KA;
2016
27190136
August 1st, 2016
Australia
Diabetic Complications Division, Baker IDI Heart & Diabetes Institute, Melbourne, Australia Department of Medicine, Monash University, Melbourne, Australia
Use of a genetically engineered mouse model as a preclinical tool for HER2 breast cancer
Disease Models and Mechanisms
Creedon, H;Balderstone, LA;Muir, M;Balla, J;Gomez-Cuadrado, L;Tracey, N;Loane, J;Klinowska, T;Muller, WJ;Brunton, VG;
2016
26721874
February 1st, 2016
United Kingdom
Edinburgh Cancer Research UK Centre, University of Edinburgh, Crewe Road South, Edinburgh EH4 2XR, UK
CK2 activity is required for the interaction of FGF14 with voltage-gated sodium channels and neuronal excitability
FASEB Journal
Hsu, WC;Scala, F;Nenov, MN;Wildburger, NC;Elferink, H;Singh, AK;Chesson, CB;Buzhdygan, T;Sohail, M;Shavkunov, AS;Panova, NI;Nilsson, CL;Rudra, JS;Lichti, CF;Laezza, F;
2016
26917740
June 1st, 2016
United States
Department of Pharmacology and Toxicology, Mitchell Center for Neurodegenerative Diseases, Center for Addiction Research, and Center for Biomedical Engineering, University of Texas Medical Branch, Galveston, Texas, USA
Sustained nitric oxide (NO)-releasing compound reverses dysregulated NO signal transduction in priapism
FASEB Journal
Lagoda, G;Sezen, SF;Hurt, KJ;Cabrini, MR;Mohanty, DK;Burnett, AL;
2014
24076963
January 1st, 2014
United States
1Department of Urology, The Johns Hopkins Hospital, 600 N. Wolfe St., Marburg 407, Baltimore, MD 21287-2411, USA
Proceedings of the Second Shanthi V. Sitaraman Intestinal Pathobiology Symposium
Inflammory Bowel Disorder Journal
Etienne-Mesmin, L;Wang, T;Viennois, E;Chassaing, B;Gewirtz, AT;Merlin, D;
2015
26389819
August 1st, 2015
United States
Center for Inflammation, Immunity, and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, Georgia
Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor
International Journal of Obesity (Lond)
Hoang-Yen Tran, D;Hoang-Ngoc Tran, D;Mattai, SA;Sallam, T;Ortiz, C;Lee, EC;Robbins, L;Ho, S;Lee, JE;Fisseha, E;Shieh, C;Sideri, A;Shih, DQ;Fleshner, P;McGovern, DP;Vu, M;Hing, TC;Bakirtzi, K;Cheng, M;Su, B;Law, I;Karagiannides, I;Targan, SR;Gallo, RL;Li, Z;Koon, HW;
2016
27163748
September 1st, 2016
United States
Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine at the University of California Los Angeles, Los Angeles, CA, USA
Intrauterine group A streptococcal infections are exacerbated by prostaglandin E2
Journal of Immunology
Mason, KL;Rogers, LM;Soares, EM;Bani-Hashemi, T;Erb Downward, J;Agnew, D;Peters-Golden, M;Weinberg, JB;Crofford, LJ;Aronoff, DM;
2013
23913961
September 1st, 2013
United States
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan Health System, Ann Arbor, MI 48109, USA
The class A scavenger receptor, macrophage receptor with collagenous structure, is the major phagocytic receptor for Clostridium sordellii expressed by human decidual macrophages
Journal of Immunology
Thelen, T;Hao, Y;Medeiros, AI;Curtis, JL;Serezani, CH;Kobzik, L;Harris, LH;Aronoff, DM;
2010
20810988
October 1st, 2010
United States
Molecular, Cellular, and Developmental Biology Graduate Program, Eastern Michigan University, Ypsilanti, MI 48197, USA
Characterization of human antiviral adaptive immune responses during hepatotropic virus infection in HLA-transgenic human immune system mice
Journal of Immunology
Billerbeck, E;Horwitz, JA;Labitt, RN;Donovan, BM;Vega, K;Budell, WC;Koo, GC;Rice, CM;Ploss, A;
2013
23833235
August 15th, 2013
United States
Laboratory of Virology and Infectious Disease, Center for the Study of Hepatitis C, The Rockefeller University, New York, NY 10065, USA
Intrinsic self-DNA triggers inflammatory disease dependent on STING
Journal of Immunology
Ahn, J;Ruiz, P;Barber, GN;
2014
25261479
November 1st, 2014
United States
Department of Cell Biology, University of Miami Miller School of Medicine, Miami, FL 33136; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136; and
Beta1 integrin is an adhesion protein for sperm binding to eggs
ACS Chemical Biology
Baessler, KA;Lee, Y;Sampson, NS;
2009
19338281
May 15th, 2009
United States
Biochemistry and Structural Biology Graduate Program, Stony Brook University, Stony Brook, NY 11794, USA
Microglial p38ë± MAPK is critical for LPS-induced neuron degeneration, through a mechanism involving TNFë±
Molecular Neurodegeneration
Xing, B;Bachstetter, AD;Van Eldik, LJ;
2011
22185458
December 20th, 2011
United States
Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA
Fibroblast Growth Factor 14 Modulates the Neurogenesis of Granule Neurons in the Adult Dentate Gyrus
Molecular Neurobiology
Alshammari, MA;Alshammari, TK;Nenov, MN;Scala, F;Laezza, F;
2016
26687232
December 1st, 2016
United States
Mitchell Center for Neurodegenerative Diseases, The University of Texas Medical Branch, Galveston, TX, USA
Role of ERalpha in the differential response of Stat5a loss in susceptibility to mammary preneoplasia and DMBA-induced carcinogenesis
Carcinogenesis
Miermont, AM;Parrish, AR;Furth, PA;
2010
20181624
June 1st, 2010
United States
Department of Oncology, Georgetown University, Washington, DC 20007, USA
NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium
Journal of Molecular and Cellular Cardiology
White, MP;Theodoris, CV;Liu, L;Collins, WJ;Blue, KW;Lee, JH;Meng, X;Robbins, RC;Ivey, KN;Srivastava, D;
2015
25871831
July 1st, 2015
United States
Gladstone Institute of Cardiovascular Disease and University of California, San Francisco, USA
Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington''s disease
Neurobiology of Disease
Swarnkar, S;Chen, Y;Pryor, WM;Shahani, N;Page, DT;Subramaniam, S;
2015
26048156
October 1st, 2015
United States
Department of Neuroscience, The Scripps Research Institute, Jupiter, Florida 33458, USA
Mitochondrial dysfunction in an Opa1(Q285STOP) mouse model of dominant optic atrophy results from Opa1 haploinsufficiency
Cell Death Discovery
Kushnareva, Y;Seong, Y;Andreyev, AY;Kuwana, T;Kiosses, WB;Votruba, M;Newmeyer, DD;
2016
27468686
July 28th, 2016
United States
Immune Regulation, La Jolla Institute for Allergy and Immunology, 9420 Athena Circle, La Jolla, CA 92037, USA
Protease induced plasticity: matrix metalloproteinase-1 promotes neurostructural changes through activation of protease activated receptor 1
Scientific Reports
Allen, M;Ghosh, S;Ahern, GP;Villapol, S;Maguire-Zeiss, KA;Conant, K;
2016
27762280
October 20th, 2016
United States
Interdisciplinary Program in Neuroscience, Georgetown University, Washington, DC, USA
Electroacupuncture in conscious free-moving mice reduces pain by ameliorating peripheral and central nociceptive mechanisms
Scientific Reports
Wang, Y;Lei, J;Gupta, M;Peng, F;Lam, S;Jha, R;Raduenz, E;Beitz, AJ;Gupta, K;
2016
27687125
September 30th, 2016
United States
Vascular Biology Center, Division of Hematology, Oncology &Transplantation, Department of Medicine, University of Minnesota, 14-100 PWB, 516 Delaware ST SE, Minneapolis, MN 55455, USA
Macrophages form functional vascular mimicry channels in vivo
Scientific Reports
Barnett, FH;Rosenfeld, M;Wood, M;Kiosses, WB;Usui, Y;Marchetti, V;Aguilar, E;Friedlander, M;
2016
27834402
November 11th, 2016
United States
Department of Cell and Molecular Biology, The Scripps Research Institute, 10550 N. Torrey Pines Rd, La Jolla, CA 92037, USA
miR-182 Modulates Myocardial Hypertrophic Response Induced by Angiogenesis in Heart
Scientific Reports
Li, N;Hwangbo, C;Jaba, IM;Zhang, J;Papangeli, I;Han, J;Mikush, N;Larriv̩e, B;Eichmann, A;Chun, HJ;Young, LH;Tirziu, D;
2016
26888314
February 18th, 2016
United States
Yale Cardiovascular Research Center, Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, CT, 06520, USA
Sensory hypo-excitability in a rat model of fetal development in Fragile X Syndrome
Scientific Reports
Berzhanskaya, J;Phillips, MA;Shen, J;Colonnese, MT;
2016
27465362
July 28th, 2016
United States
College of Mechanical and Electronic Engineering, Northwest A&F University, Washington, DC 20052, United States
The astrocytic transporter SLC7A10 (Asc-1) mediates glycinergic inhibition of spinal cord motor neurons
Scientific Reports
Ehmsen, JT;Liu, Y;Wang, Y;Paladugu, N;Johnson, AE;Rothstein, JD;du Lac, S;Mattson, MP;H̦ke, A;
2016
27759100
October 19th, 2016
United States
Department of Neurology, Johns Hopkins School of Medicine, 855 N. Wolfe Street, Baltimore, Maryland, 21205, USA
Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis
Scientific Reports
O'Conor, CJ;Ramalingam, S;Zelenski, NA;Benefield, HC;Rigo, I;Little, D;Wu, CL;Chen, D;Liedtke, W;McNulty, AL;Guilak, F;
2016
27388701
July 8th, 2016
United States
Department of Orthopaedic Surgery, Washington University in St. Louis, Missouri, 63110, USA
Magnetic Resonance Spectroscopy discriminates the response to microglial stimulation of wild type and Alzheimer''s disease models
Scientific Reports
Pardon, MC;Yanez Lopez, M;Yuchun, D;MarjaÂãska, M;Prior, M;Brignell, C;Parhizkar, S;Agostini, A;Bai, L;Auer, DP;Faas, HM;
2016
26813748
January 27th, 2016
United Kingdom
Neuroscience, School of Life Sciences, University of Nottingham United Kingdom
Microfluidic squeezing for intracellular antigen loading in polyclonal B-cells as cellular vaccines
Scientific Reports
Szeto, GL;Van Egeren, D;Worku, H;Sharei, A;Alejandro, B;Park, C;Frew, K;Brefo, M;Mao, S;Heimann, M;Langer, R;Jensen, K;Irvine, DJ;
2015
25999171
May 22nd, 2015
United States
1] Department of Materials Science &Engineering, MIT [2] Department of Biological Engineering, MIT [3] David. H. Koch Institute for Integrative Cancer Research, MIT [4] The Ragon Institute of Harvard, MIT, and MGH
Crumbs3 is essential for proper epithelial development and viability
Molelcular and Cellular Biology
Whiteman, EL;Fan, S;Harder, JL;Walton, KD;Liu, CJ;Soofi, A;Fogg, VC;Hershenson, MB;Dressler, GR;Deutsch, GH;Gumucio, DL;Margolis, B;
2014
24164893
January 1st, 2014
United States
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, USA
Enhanced Cognition and Hypoglutamatergic Signaling in a Growth Hormone Receptor Knockout Mouse Model of Successful Aging
Journals of Gerontology
Hascup, KN;Lynn, MK;Fitzgerald, PJ;Randall, S;Kopchick, JJ;Boger, HA;Bartke, A;Hascup, ER;
2016
27208894
May 21st, 2016
United States
Department of Neurology, Center for Alzheimer's Disease and Related Disorders, Southern Illinois University School of Medicine, Springfield. Department of Pharmacology, Southern Illinois University School of Medicine, Springfield
Primary cancer cell culture: mammary-optimized vs conditional reprogramming
Endocrine Related Cancer
Alamri, AM;Kang, K;Groeneveld, S;Wang, W;Zhong, X;Kallakury, B;Hennighausen, L;Liu, X;Furth, PA;
2016
27267121
July 1st, 2016
United States
Department of OncologyLombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA Department of MedicineLombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia, USA
Microglial p38ë± MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aë_)
Journal of Neuroinflammation
Bachstetter, AD;Xing, B;de Almeida, L;Dimayuga, ER;Watterson, DM;Van Eldik, LJ;
2011
21733175
July 6th, 2011
United States
Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, USA
The p38alpha mitogen-activated protein kinase limits the CNS proinflammatory cytokine response to systemic lipopolysaccharide, potentially through an IL-10 dependent mechanism
Journal of Neuroinflammation
Bachstetter, AD;Xing, B;Van Eldik, LJ;
2014
25297465
October 10th, 2014
United States
Sanders-Brown Center on Aging, University of Kentucky, 800 S, Limestone Street, Lexington 40536, KY, USA
Age exacerbates the CCR2/5-mediated neuroinflammatory response to traumatic brain injury
Journal of Neuroinflammation
Morganti, JM;Riparip, LK;Chou, A;Liu, S;Gupta, N;Rosi, S;
2016
27090212
April 18th, 2016
United States
Brain and Spinal Injury Center, University of California, 1001 Potrero Ave, Bldg. 1, Room 101, San Francisco, CA, 94110, USA
Deficiency of complement receptors CR2/CR1 in Cr2‰ÂÈ/‰ÂÈ mice reduces the extent of secondary brain damage after closed head injury
Journal of Neuroinflammation
Neher, MD;Rich, MC;Keene, CN;Weckbach, S;Bolden, AL;Losacco, JT;Patane, J;Flierl, MA;Kulik, L;Holers, VM;Stahel, PF;
2014
24885042
May 24th, 2014
United States
Department of Orthopedic Surgery, Denver Health Medical Center, University of Colorado School of Medicine, 777 Bannock Street, Denver CO 80204, USA
Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease
Neurobiology of Aging
Rosa, E;Mahendram, S;Ke, YD;Ittner, LM;Ginsberg, SD;Fahnestock, M;
2016
27676333
August 31st, 2016
Canada
Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada
Accelerated protein damage in brains of PIMT+/- mice; a possible model for the variability of cognitive decline in human aging
Neurobiology of Aging
Qin, Z;Dimitrijevic, A;Aswad, DW;
2015
25465735
February 1st, 2015
United States
Department of Molecular Biology & Biochemistry, University of California, Irvine, Irvine, CA, USA
CB䉉 receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease
Molecular Medicine
Koppel, J;Vingtdeux, V;Marambaud, P;d'Abramo, C;Jimenez, H;Stauber, M;Friedman, R;Davies, P;
2013
24408112
November 8th, 2013
United States
Litwin-Zucker Research Center, Feinstein Institute for Medical Research, North-Shore Long Island Jewish Health System, Manhasset, New York, United States of America
Transcriptional dysregulation causes altered modulation of inhibition by haloperidol
Neuropharmacology
Brady, LJ;Bartley, AF;Li, Q;McMeekin, LJ;Hablitz, JJ;Cowell, RM;Dobrunz, LE;
2016
27480797
December 1st, 2016
United States
Department of Neurobiology and Evelyn F. McKnight Brain Institute, University of Alabama at Birmingham, 1825 University Blvd., Birmingham, AL, USA; Civitan International Research Center, University of Alabama at Birmingham, 1719 6th Ave. S., Birmingham, AL, USA
In vitro gamma oscillations following partial and complete ablation of ë« subunit-containing GABAA receptors from parvalbumin interneurons
Neuropharmacology
Ferando, I;Mody, I;
2015
25261782
January 1st, 2015
United States
Departments of Neurology, The David Geffen School of Medicine, University of California, Los Angeles, CA, USA; Departments of Physiology, The David Geffen School of Medicine, University of California, Los Angeles, CA, USA
Monitoring cholinergic activity during attentional performance in mice heterozygous for the choline transporter: a model of cholinergic capacity limits
Neuropharmacology
Paolone, G;Mallory, CS;Koshy Cherian, A;Miller, TR;Blakely, RD;Sarter, M;
2013
23958450
December 1st, 2013
United States
Department of Psychology & Neuroscience Program, University of Michigan, Ann Arbor, MI 48103, USA
Attenuated p53 activation in tumour-associated stromal cells accompanies decreased sensitivity to etoposide and vincristine
British Journal of Cancer
Dudley, AC;Shih, SC;Cliffe, AR;Hida, K;Klagsbrun, M;
2008
18594537
July 1st, 2008
United States
Vascular Biology Program, Department of Surgery, Children's Hospital and Harvard Medical School, Boston, MA 02115, USA
The ability of an attaching and effacing pathogen to trigger localized actin assembly contributes to virulence by promoting mucosal attachment
Cellular Microbiology
Mallick, EM;Garber, JJ;Vanguri, VK;Balasubramanian, S;Blood, T;Clark, S;Vingadassalom, D;Louissaint, C;McCormick, B;Snapper, SB;Leong, JM;
2014
24780054
September 1st, 2014
United States
Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA, 01655, USA
Fatty Acid-Binding Protein 5 Facilitates the Blood-Brain Barrier Transport of Docosahexaenoic Acid
Molecular Pharmaceutics
Pan, Y;Scanlon, MJ;Owada, Y;Yamamoto, Y;Porter, CJ;Nicolazzo, JA;
2015
26455443
December 1st, 2015
Australia
Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences,Monash University, 399 Royal Parade, Parkville, Victoria 3052, Australia
KISS1R signals independently of Gë±q/11 and triggers LH secretion via the ë_-arrestin pathway in the male mouse
Endocrinology
Ahow, M;Min, L;Pampillo, M;Nash, C;Wen, J;Soltis, K;Carroll, RS;Glidewell-Kenney, CA;Mellon, PL;Bhattacharya, M;Tobet, SA;Kaiser, UB;Babwah, AV;
2014
25147978
November 1st, 2014
Canada
Children's Health Research Institute, Victoria Research Laboratories, A4‰ÛÒ140, 800 Commissioners Road East, London, Ontario, Canada N6C 2V5.
Reduced melanocortin production causes sexual dysfunction in male mice with POMC neuronal insulin and leptin insensitivity
Endocrinology
Faulkner, LD;Dowling, AR;Stuart, RC;Nillni, EA;Hill, JW;
2015
25590244
April 1st, 2015
United States
Department of Physiology and Pharmacology (L.D.F., A.R.D., J.W.H.), College of Medicine, The University of Toledo, Toledo, Ohio 43614-2598; and Division of Endocrinology (R.C.S., E.A.N.), Department of Medicine, The Warren Alpert Medical School of Brown University, Providence, Rhode Island 02912-9107
Delayed puberty but normal fertility in mice with selective deletion of insulin receptors from Kiss1 cells
Endocrinology
Qiu, X;Dowling, AR;Marino, JS;Faulkner, LD;Bryant, B;BrÌ_ning, JC;Elias, CF;Hill, JW;
2013
23392256
March 1st, 2013
United States
Center for Diabetes and Endocrine Research, University of Toledo College of Medicine, Toledo, OH 43614, USA
Mechanisms of amylin/leptin synergy in rodent models
Endocrinology
Turek, VF;Trevaskis, JL;Levin, BE;Dunn-Meynell, AA;Irani, B;Gu, G;Wittmer, C;Griffin, PS;Vu, C;Parkes, DG;Roth, JD;
2010
19875640
January 1st, 2010
United States
Amylin Pharmaceuticals, Inc., 9360 Towne Centre Drive, San Diego, California 92121, USA
Regulation of brain PPARgamma2 contributes to ketogenic diet anti-seizure efficacy
Experimental Neurology
Simeone, TA;Matthews, SA;Samson, KK;Simeone, KA;
2017
27527983
January 1st, 2017
United States
Creighton University, School of Medicine, Department of Pharmacology, Omaha, NE 68174, USA
Preservation of neuromuscular function in symptomatic SOD1-G93A mice by peripheral infusion of methylene blue
Experimental Neurology
Talbot, JD;Barrett, JN;Nonner, D;Zhang, Z;Wicomb, K;Barrett, EF;
2016
27567739
November 1st, 2016
United States
Department of Physiology and Biophysics, University of Miami Miller School of Medicine, P.O. Box 016430, Miami, FL 33101, USA; Neuroscience Program, University of Miami Miller School of Medicine, Miami, FL, USA 33101
Desert hedgehog is a mediator of demyelination in compression neuropathies
Experimental Neurology
Jung, J;Frump, D;Su, J;Wang, W;Mozaffar, T;Gupta, R;
2015
25936873
September 1st, 2015
United States
Department of Orthopaedic Surgery, University of California, Irvine, CA 92697, USA; Department of Biomedical Engineering, University of California, Irvine, CA 92697, USA; Department of Anatomy and Neurobiology, University of California, Irvine, CA 92697, USA
BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle
American Journal of Pathology
Kennedy, TL;Swiderski, K;Murphy, KT;Gehrig, SM;Curl, CL;Chandramouli, C;Febbraio, MA;Delbridge, LM;Koopman, R;Lynch, GS;
2016
27750047
December 1st, 2016
Australia
Basic and Clinical Myology Laboratory, Department of Physiology, The University of Melbourne, Melbourne, Victoria
The PPARë_ agonist efatutazone increases the spectrum of well-differentiated mammary cancer subtypes initiated by loss of full-length BRCA1 in association with TP53 haploinsufficiency
American Journal of Pathology
Nakles, RE;Kallakury, BV;Furth, PA;
2013
23664366
June 1st, 2013
United States
Department of Oncology, Georgetown University, Washington, District of Columbia 20057, USA
The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity
Journal of Biological Chemisrty
Clement, CC;Becerra, A;Yin, L;Zolla, V;Huang, L;Merlin, S;Follenzi, A;Shaffer, SA;Stern, LJ;Santambrogio, L;
2016
26740625
March 11th, 2016
United States
From the Departments of Pathology and Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York 10461
Hepatic Insulin Resistance Following Chronic Activation of the CREB Coactivator CRTC2
Journal of Biological Chemisrty
Hogan, MF;Ravnskjaer, K;Matsumura, S;Huising, MO;Hull, RL;Kahn, SE;Montminy, M;
2015
26342077
October 23rd, 2015
United States
From the Peptide Biology Laboratories, Salk Institute for Biological Studies, La Jolla, California 92037
Central Mechanisms Mediating Thrombospondin-4-induced Pain States
Journal of Biological Chemisrty
Park, J;Yu, YP;Zhou, CY;Li, KW;Wang, D;Chang, E;Kim, DS;Vo, B;Zhang, X;Gong, N;Sharp, K;Steward, O;Vitko, I;Perez-Reyes, E;Eroglu, C;Barres, B;Zaucke, F;Feng, G;Luo, ZD;
2016
27129212
June 17th, 2016
United States
From the Department of Pharmacology and Department of Anesthesiology and Perioperative Care, University of California, Irvine, California 92697, Reeve-Irvine Research Center, University of California, Irvine, School of Medicine, Irvine, California 92697
Purinergic control of hippocampal circuit hyperexcitability in Dravet syndrome
Epilepsia
Gu, F;Hazra, A;Aulakh, A;Â_iburkus, J;
2014
24417577
February 1st, 2014
United States
Department of Biology and Biochemistry, University of Houston, Houston, Texas, U.S.A
In vivo ketogenic diet treatment attenuates pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices from epileptic Kv 1.1ë± knockout mice
Epilepsia
Simeone, TA;Samson, KK;Matthews, SA;Simeone, KA;
2014
24702645
May 1st, 2014
United States
Department of Pharmacology, School of Medicine, Creighton University, Omaha, Nebraska, U.S.A
Optogenetic stimulation of cholinergic brainstem neurons during focal limbic seizures: Effects on cortical physiology
Epilepsia
Furman, M;Zhan, Q;McCafferty, C;Lerner, BA;Motelow, JE;Meng, J;Ma, C;Buchanan, GF;Witten, IB;Deisseroth, K;Cardin, JA;Blumenfeld, H;
2015
26530287
December 1st, 2015
United States
Department of Neurology, Yale University School of Medicine, New Haven, Connecticut, U.S.A
Ketogenic diet treatment increases longevity in Kcna1-null mice, a model of sudden unexpected death in epilepsy
Epilepsia
Simeone, KA;Matthews, SA;Rho, JM;Simeone, TA;
2016
27346881
August 1st, 2016
United States
Department of Pharmacology, Creighton University School of Medicine, Omaha, Nebraska, U.S.A
Ketogenic diet treatment abolishes seizure periodicity and improves diurnal rhythmicity in epileptic Kcna1-null mice
Epilepsia
Fenoglio-Simeone, KA;Wilke, JC;Milligan, HL;Allen, CN;Rho, JM;Maganti, RK;
2009
19490051
September 1st, 2009
United States
Barrow Neurological Institute and St. Joseph's Medical Center, Neurology Research, Phoenix, Arizona 85013, USA
Research tool: Validation of floxed ë±7 nicotinic acetylcholine receptor conditional knockout mice using in vitro and in vivo approaches
Journal of Physiology (London)
Hernandez, CM;Cortez, I;Gu, Z;ColÃŒ_n-SÃŒÃez, JO;Lamb, PW;Wakamiya, M;Yakel, JL;Dineley, KT;
2014
24879866
August 1st, 2014
United States
Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch at Galveston (UTMB), Galveston, TX, USA Department of Neurology, UTMB, Galveston, TX, USA Rodent In Vivo Assessment Core, UTMB, Galveston, TX, USA Center for Addiction Research, UTMB, Galveston, TX, USA
Fluorescence recovery after photobleaching reveals regulation and distribution of connexin36 gap junction coupling within mouse islets of Langerhans
Journal of Physiology (London)
Farnsworth, NL;Hemmati, A;Pozzoli, M;Benninger, RK;
2014
25172942
October 15th, 2014
United States
Barbara Davis Center for Childhood Diabetes, University of Colorado, Aurora, CO, USA Department of Bioengineering, University of Colorado, Aurora, CO, USA
Utrophin regulates modal gating of mechanosensitive ion channels in dystrophic skeletal muscle
Journal of Physiology (London)
Tan, N;Lansman, JB;
2014
24879867
August 1st, 2014
United States
Department of Cellular and Molecular Pharmacology, School of Medicine, University of California, San Francisco, San Francisco, CA, 94143-0450, USA
CLC-3 chloride channels moderate long-term potentiation at Schaffer collateral-CA1 synapses
Journal of Physiology (London)
Farmer, LM;Le, BN;Nelson, DJ;
2013
23165767
February 15th, 2013
United States
Department of Neurobiology, Pharmacology and Physiology, The University of Chicago, Chicago, IL 60637, USA
Physiological and morphological properties of Dbx1-derived respiratory neurons in the pre-Botzinger complex of neonatal mice
Journal of Physiology (London)
Picardo, MC;Weragalaarachchi, KT;Akins, VT;Del Negro, CA;
2013
23459755
May 15th, 2013
United States
Department of Applied Science, McGlothlin-Street Hall, Room 318, The College of William & Mary, Williamsburg, VA 23187-8795, USA
Is connexin36 critical for GABAergic hypersynchronization in the hippocampus?
Journal of Physiology (London)
Beaumont, M;Maccaferri, G;
2011
21300748
April 1st, 2011
United States
Northwestern University Interdepartmental Neuroscience Program, Department of Physiology, Feinberg School of Medicine, 303 E Chicago Ave, Tarry Blg Rm 5-707, Chicago, IL 60611, USA
Automated cell-specific laser detection and ablation of neural circuits in neonatal brain tissue
Journal of Physiology (London)
Wang, X;Hayes, JA;Picardo, MC;Del Negro, CA;
2013
23440965
May 15th, 2013
United States
Department of Applied Science, McGlothlin-Street Hall, Room 318, The College of William & Mary, Williamsburg, VA 23187-8795, USA
T-bet is essential for Th1-mediated, but not Th17-mediated, CNS autoimmune disease
European Journal of Immunology
O'Connor, RA;Cambrook, H;Huettner, K;Anderton, SM;
2013
23878019
November 1st, 2013
United Kingdom
Medical Research Council Centre for Inflammation Research, Centre for Multiple Sclerosis Research and Centre for Immunity Infection and Evolution, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK
CD40 engagement of CD4+ CD40+ T cells in a neo-self antigen disease model ablates CTLA-4 expression and indirectly impacts tolerance
European Journal of Immunology
Carter, J;Vaitaitis, GM;Waid, DM;Wagner, DH;
2012
22105491
February 1st, 2012
United States
The Webb-Waring Center, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
Lineage tracking of mesenchymal and endothelial progenitors in BMP-induced bone formation
Bone
Kolind, M;Bobyn, JD;Matthews, BG;Mikulec, K;Aiken, A;Little, DG;Kalajzic, I;Schindeler, A;
2015
26141839
December 1st, 2015
Australia
Centre for Children's Bone Health, The Children's Hospital at Westmead, Westmead, NSW, Australia; Discipline of Paediatrics and Child Health, Faculty of Medicine, University of Sydney, Sydney, NSW, Australia
Activity-dependent neuroprotective protein (ADNP) exhibits striking sexual dichotomy impacting on autistic and Alzheimer's pathologies
Translational Psychiatry
Malishkevich, A;Amram, N;Hacohen-Kleiman, G;Magen, I;Giladi, E;Gozes, I;
2015
25646590
February 3rd, 2015
Israel
The Lily and Avraham Gildor Chair for Investigation of Growth Factors; The Elton Laboratory for Molecular Neuroendocrinology, Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Sagol School of Neuroscience and Adams Super Center for Brain Studies, Tel Aviv University, Tel Aviv, Israel
The activin A antagonist follistatin inhibits cystic fibrosis-like lung inflammation and pathology
Immunology and Cell Biology
Hardy, CL;King, SJ;Mifsud, NA;Hedger, MP;Phillips, DJ;Mackay, F;de Kretser, DM;Wilson, JW;Rolland, JM;O'Hehir, RE;
2015
25753271
July 1st, 2015
United States
1] Department of Allergy, Immunology & Respiratory Medicine, Central Clinical School, Monash University, Melbourne, Victoria, Australia [2] Department of Immunology, Central Clinical School, Monash University, Melbourne, Victoria, Australia
Mutation-independent rescue of a novel mouse model of Retinitis Pigmentosa
Gene Therapy
Greenwald, DL;Cashman, SM;Kumar-Singh, R;
2013
22809998
April 1st, 2013
United States
Department of Ophthalmology, Tufts University School of Medicine, Boston, MA 02111, USA
Ovarian cycle-linked plasticity of ë«-GABAA receptor subunits in hippocampal interneurons affects ë_ oscillations in vivo
Frontiers in Cellular Neuroscience
Barth, AM;Ferando, I;Mody, I;
2014
25157218
August 26th, 2014
United States
Department of Neurology, The David Geffen School of Medicine, University of California at Los Angeles Los Angeles, CA, USA ; Department of Physiology, The David Geffen School of Medicine, University of California at Los Angeles Los Angeles, CA, USA
Regulation of ethanol intake under chronic mild stress: roles of dopamine receptors and transporters
Frontiers in Behavioral Neuroscience
Delis, F;Rombola, C;Bellezza, R;Rosko, L;Grandy, DK;Volkow, ND;Thanos, PK;
2015
26029066
June 1st, 2015
United States
Department of Psychology, State University of New York at Stony Brook Stony Brook, NY, USA
TIR Domain-Containing Adapter-Inducing Beta Interferon (TRIF) Mediates Immunological Memory against Bacterial Pathogens
Infection and Immunity
Kanagavelu, S;Flores, C;Termini, JM;Romero, L;Riveron, R;Ruiz, J;Arditi, M;Schesser, K;Fukata, M;
2015
26351279
November 1st, 2015
United States
Division of Gastroenterology, Department of Medicine, Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, California, USA Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, California, USA
SOCS-3 Regulates Alveolar Bone Loss in Experimental Periodontitis
Journal of Dental Research
Papathanasiou, E;Kantarci, A;Konstantinidis, A;Gao, H;Van Dyke, TE;
2016
27126447
August 1st, 2016
United States
Department of Applied Oral Sciences, Center for Periodontology, Forsyth Institute, Cambridge, MA, USA
Skeletal muscle glucose uptake during treadmill exercise in neuronal nitric oxide synthase-ë_ knockout mice
American Journal of Physiology Endocrinology and Metabolism
Hong, YH;Yang, C;Betik, AC;Lee-Young, RS;McConell, GK;
2016
27006199
May 15th, 2016
Malaysia
College of Health and Biomedicine, Victoria University, Melbourne, Victoria, Australia; Clinical Exercise Science Program, Institute of Sport, Exercise and Active Living, Victoria University, Melbourne, Victoria, Australia; Department of Physiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia; and
The absence of 25-hydroxyvitamin D3-1ë±-hydroxylase potentiates the suppression of EAE in mice by ultraviolet light
Journal of Steroid Biochemistry and Molecular Biology
Wang, Y;Marling, SJ;Martino, VM;Prahl, JM;Deluca, HF;
2016
27108944
October 1st, 2016
United States
Department of Biochemistry, University of Wisconsin-Madison, 433 Babcock Drive, Madison, WI 53706-1544, United States
Fibroblast-specific expression of AC6 enhances beta-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis
American Journal of Physiology Lung Cellular and Molecular Physiology
Liu, X;Li, F;Sun, SQ;Thangavel, M;Kaminsky, J;Balazs, L;Ostrom, RS;
2010
20348281
June 1st, 2010
United States
Department of Pharmacology, University of Tennessee Health Science Center, Memphis, TN 38163, USA
Periostin promotes fibrosis and predicts progression in patients with idiopathic pulmonary fibrosis
American Journal of Physiology Lung Cellular and Molecular Physiology
Naik, PK;Bozyk, PD;Bentley, JK;Popova, AP;Birch, CM;Wilke, CA;Fry, CD;White, ES;Sisson, TH;Tayob, N;Carnemolla, B;Orecchia, P;Flaherty, KR;Hershenson, MB;Murray, S;Martinez, FJ;Moore, BB;, ;
2012
23043074
December 15th, 2012
United States
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA
Toll-like receptor 2 mediates mesenchymal stem cell-associated myocardial recovery and VEGF production following acute ischemia-reperfusion injury
American Journal of Physiology Heart and Circulatory Physiology
Abarbanell, AM;Wang, Y;Herrmann, JL;Weil, BR;Poynter, JA;Manukyan, MC;Meldrum, DR;
2010
20173040
May 1st, 2010
United States
Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA
ApoE deficiency exacerbates the development and sustainment of a semi-chronic K/BxN serum transfer-induced arthritis model
Journal of Translational Medicine
Archer, AM;Saber, R;Rose, S;Shaffer, A;Misharin, AV;Tsai, F;Haines Iii, GK;Dominguez, S;Eren, M;Vaughan, DE;Cuda, CM;Perlman, H;
2016
27287704
June 10th, 2016
United States
Division of Rheumatology, Department of Medicine, Northwestern University Feinberg School of Medicine, 240 East Huron Street, McGaw M338, Chicago, IL, 60611, USA
EP2 and EP4 receptors mediate PGE2 induced relaxation in murine colonic circular muscle: pharmacological characterization
Pharmacology Research
Martinez-Cutillas, M;Ma̱̩, N;Gallego, D;Jimenez, M;Martin, MT;
2014
25461458
December 1st, 2014
Spain
Department of Cell Biology, Physiology and Immunology, Universitat AutÃŒ_noma de Barcelona, Barcelona, Spain; Centro de InvestigaciÃŒ_n BiomÌ©dica en Red de Enfermedades HepÃŒÃticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Barcelona, Spain
Males are from Mars, and females are from Venus: sex-specific fetal brain gene expression signatures in a mouse model of maternal diet-induced obesity
American Journal of Obsterics and Gynecology
Edlow, AG;Guedj, F;Pennings, JL;Sverdlov, D;Neri, C;Bianchi, DW;
2016
26945603
May 1st, 2016
United States
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Tufts Medical Center, Boston, MA; Mother Infant Research Institute, Tufts Medical Center, Boston, MA
Network of brain protein level changes in glutaminase deficient fetal mice
Journal of Proteomics
Bae, N;Wang, Y;Li, L;Rayport, S;Lubec, G;
2013
23376484
March 27th, 2013
Austria
Department of Pediatrics, Medical University of Vienna, WÌ_hringer GÌ_rtel 18, 1090 Vienna, Austria
Neurological Dysfunction in Early Maturity of a Model for Niemann-Pick C1 Carrier Status
Neurotherapeutics
Hung, YH;Walterfang, M;Churilov, L;Bray, L;Jacobson, LH;Barnham, KJ;Jones, NC;O'Brien, TJ;Velakoulis, D;Bush, AI;
2016
26942423
July 1st, 2016
Australia
Oxidation Biology Unit, The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Parkville, Victoria, 3010, Australia
Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity
Journal of Pharmacology and Expreimental Therapeutics
Longo, KA;Govek, EK;Nolan, A;McDonagh, T;Charoenthongtrakul, S;Giuliana, DJ;Morgan, K;Hixon, J;Zhou, C;Kelder, B;Kopchick, JJ;Saunders, JO;Navia, MA;Curtis, R;DiStefano, PS;Geddes, BJ;
2011
21775475
October 1st, 2011
United States
Elixir Pharmaceuticals, Inc, Cambridge, Massachusetts, USA
Enhancing eNOS activity with simultaneous inhibition of IKKë_ restores vascular function in Ins2(Akita+/-) type-1 diabetic mice
Laboratory Investigation
Krishnan, M;Janardhanan, P;Roman, L;Reddick, RL;Natarajan, M;van Haperen, R;Habib, SL;de Crom, R;Mohan, S;
2015
26214584
October 1st, 2015
United States
Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
Quantitative assessment of pancreatic cancer precursor lesions in IHC-stained tissue with a tissue image analysis platform
Laboratory Investigation
Aeffner, F;Martin, NT;Peljto, M;Black, JC;Major, JK;Jangani, M;Ports, MO;Krueger, JS;Young, GD;
2016
27775692
December 1st, 2016
United States
Flagship Biosciences Inc., Westminster, CO, USA
Mice lacking sialyltransferase ST3Gal-II develop late onset obesity and insulin resistance
Glycobiology
Lopez, PH;Aja, S;Aoki, K;Seldin, MM;Lei, X;Ronnett, GV;Wong, GW;Schnaar, RL;
2016
27683310
September 28th, 2016
United States
Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, 21205 USA Departments of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, 21205 USA
c-Met signalling is required for efficient postnatal thymic regeneration and repair
Immunology
Song, Y;Su, M;Panchatsharam, P;Rood, D;Lai, L;
2015
25074726
February 1st, 2015
United States
Department of Allied Health Sciences, University of Connecticut, Storrs, CT, USA
Nervous-tissue-specific elimination of microtubule-actin crosslinking factor 1a results in multiple developmental defects in the mouse brain
Molecular and Cellular Neuroscience
Goryunov, D;He, CZ;Lin, CS;Leung, CL;Liem, RK;
2010
20170731
May 1st, 2010
United States
Department of Pathology and Cell Biology, Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University College of Physicians and Surgeons, NY, NY 10032, USA
Cooperative regulation of neurotransmitter release by Rab3a and synapsin II
Molecular and Cellular Neuroscience
Coleman, WL;Bykhovskaia, M;
2010
20338242
June 1st, 2010
United States
Department of Biological Sciences, Lehigh University, Bethlehem, PA, USA
Tissue inducible Lifeact expression allows visualization of actin dynamics in vivo and ex vivo
European Journal of Cell Biology
Schachtner, H;Li, A;Stevenson, D;Calaminus, SD;Thomas, SG;Watson, SP;Sixt, M;Wedlich-Soldner, R;Strathdee, D;Machesky, LM;
2012
22658956
October 15th, 2012
United Kingdom
The Beatson Institute for Cancer Research, Garscube Estate, Bearsden, Glasgow, United Kingdom
Mis-expression of the BK K(+) channel disrupts suprachiasmatic nucleus circuit rhythmicity and alters clock-controlled behavior
American Journal of Physiology, Cell Physiology
Montgomery, JR;Whitt, JP;Wright, BN;Lai, MH;Meredith, AL;
2013
23174562
February 15th, 2013
United States
Department of Physiology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Delayed in vitro development of Up states but normal network plasticity in Fragile X circuits
European Journal of Neuroscience
Motanis, H;Buonomano, D;
2015
26138886
September 1st, 2015
United States
Departments of Neurobiology and Psychology, Integrative Center for Learning and Memory, University of California, 695 Young Drive, Gonda, Los Angeles, CA, 90095, USA
Dopamine increases NMDA-stimulated calcium flux in striatopallidal neurons through a matrix metalloproteinase-dependent mechanism
European Journal of Neuroscience
Li, Y;Partridge, J;Berger, C;Sepulveda-Rodriguez, A;Vicini, S;Conant, K;
2016
26660285
January 1st, 2016
United States
Departments of Neuroscience and Pharmacology, Georgetown University, 3970 Reservoir Road, Washington, DC, USA
Intact brown adipose tissue thermogenesis is required for restorative sleep responses after sleep loss
European Journal of Neuroscience
Szentirmai, Ìä;KapÃŒÃs, L;
2014
24372950
March 1st, 2014
United States
Washington, Wyoming, Alaska, Montana and Idaho (WWAMI) Medical Education Program, PO Box 1495, Spokane, WA 99210-1495, USA; Department of Integrative Physiology and Neuroscience, Pullman, WA, USA; Sleep and Performance Research Center, Washington State University, Spokane, WA, USA
Impaired wake-promoting mechanisms in ghrelin receptor-deficient mice
European Journal of Neuroscience
Esposito, M;Pellinen, J;KapÃŒÃs, L;Szentirmai, Ìä;
2012
22211783
January 1st, 2012
United States
Washington, Wyoming, Alaska, Montana and Idaho (WWAMI) Medical Education Program, Washington State University, PO Box 1495, Spokane, WA 99210-1495, USA
5'-Ectonucleotidase-knockout mice lack non-REM sleep responses to sleep deprivation
European Journal of Neuroscience
Zielinski, MR;Taishi, P;Clinton, JM;Krueger, JM;
2012
22540145
June 1st, 2012
United States
Sleep and Performance Research Center, Programs in Neuroscience, WWAMI Medical Education Program, Washington State University, Spokane, WA 99210-1495, USA
RPGR-associated retinal degeneration in human X-linked RP and a murine model
Investigative Ophthalmology and Visual Science
Huang, WC;Wright, AF;Roman, AJ;Cideciyan, AV;Manson, FD;Gewaily, DY;Schwartz, SB;Sadigh, S;Limberis, MP;Bell, P;Wilson, JM;Swaroop, A;Jacobson, SG;
2012
22807293
August 15th, 2012
United States
Scheie Eye Institute, Department of Ophthalmology, University of Pennsylvania, Philadelphia, Pennsylvania, USA
L450W and Q455K Col8a2 knock-in mouse models of Fuchs endothelial corneal dystrophy show distinct phenotypes and evidence for altered autophagy
Investigative Ophthalmology and Visual Science
Meng, H;Matthaei, M;Ramanan, N;Grebe, R;Chakravarti, S;Speck, CL;Kimos, M;Vij, N;Eberhart, CG;Jun, AS;
2013
23422828
March 28th, 2013
United States
Wilmer Eye Institute, Johns Hopkins Medical Institutions, Baltimore, Maryland 21231, USA
Altered Refractive Development in Mice With Reduced Levels of Retinal Dopamine
Investigative Ophthalmology and Visual Science
Bergen, MA;Park, HN;Chakraborty, R;Landis, EG;Sidhu, C;He, L;Iuvone, PM;Pardue, MT;
2016
27750284
August 1st, 2016
United States
Center for Visual and Neurocognitive Rehabilitation, Atlanta VA Medical Center, Decatur, Georgia, United States 2Biology, Emory University, Atlanta, Georgia, United States
Isoaspartyl protein damage and repair in mouse retina
Investigative Ophthalmology and Visual Science
Qin, Z;Yang, J;Klassen, HJ;Aswad, DW;
2014
24550364
March 13th, 2014
United States
Department of Molecular Biology and Biochemistry, University of California, Irvine, California
Reduced ocular blood flow as an early indicator of diabetic retinopathy in a mouse model of diabetes
Investigative Ophthalmology and Visual Science
Muir, ER;RenterÌ_a, RC;Duong, TQ;
2012
22915034
September 21st, 2012
United States
Research Imaging Institute, University of Texas Health Science Center, San Antonio, Texas 78229, USA
The D-isoAsp-25 variant of histone H2B is highly enriched in active chromatin: potential role in the regulation of gene expression?
Amino Acids
Qin, Z;Zhu, JX;Aswad, DW;
2016
26666674
February 1st, 2016
China
Department of Molecular Biology and Biochemistry, University of California, 3205 McGaugh Hall, Irvine, CA, 92697-3900, USA
WDR72 models of structure and function: a stage-specific regulator of enamel mineralization
Matrix Biology
Katsura, KA;Horst, JA;Chandra, D;Le, TQ;Nakano, Y;Zhang, Y;Horst, OV;Zhu, L;Le, MH;DenBesten, PK;
2014
25008349
September 1st, 2014
United States
Department of Oral and Craniofacial Sciences, School of Dentistry, University of California, San Francisco, 513 Parnassus Ave., San Francisco, CA 94143-0422, USA
p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas
Developmental Biology
Hendley, AM;Provost, E;Bailey, JM;Wang, YJ;Cleveland, MH;Blake, D;Bittman, RW;Roeser, JC;Maitra, A;Reynolds, AB;Leach, SD;
2015
25523391
March 1st, 2015
United States
Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; The McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Division of Gastroenterology, Hepatology and Nutrition, Department of Internal Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
A quantitative method for defining high-arched palate using the Tcof1(+/-) mutant mouse as a model
Developmental Biology
Conley, ZR;Hague, M;Kurosaka, H;Dixon, J;Dixon, MJ;Trainor, PA;
2016
26772999
July 15th, 2016
United States
The Stowers Institute for Medical Research, Kansas City, MO, United States; Department of Anatomy and Cell Biology, University of Kansas Medical Center, Kansas City, KS, United States
Integrin-ë±5ë_1 is not required for mural cell functions during development of blood vessels but is required for lymphatic-blood vessel separation and lymphovenous valve formation
Developmental Biology
Turner, CJ;Badu-Nkansah, K;Crowley, D;van der Flier, A;Hynes, RO;
2014
24858485
August 15th, 2014
United States
Howard Hughes Medical Institute, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice
Toxicology and Applied Pharmacology
Harrill, JA;Hukkanen, RR;Lawson, M;Martin, G;Gilger, B;Soldatow, V;Lecluyse, EL;Budinsky, RA;Rowlands, JC;Thomas, RS;
2013
23859880
October 15th, 2013
United States
The Hamner Institute for Health Sciences, Institute for Chemical Safety Sciences, RTP, NC 27709, USA
MKP1-dependent PTH modulation of bone matrix mineralization in female mice is osteoblast maturation stage specific and involves P-ERK and P-p38 MAPKs
Journal of Endocrinology
Mahalingam, CD;Sampathi, BR;Sharma, S;Datta, T;Das, V;Abou-Samra, AB;Datta, NS;
2013
23197743
March 1st, 2013
United States
Division of Endocrinology, Department of Internal Medicine, Wayne State University School of Medicine, 1107 Elliman Clinical Research Building, 421 East Canfield Avenue, Detroit, Michigan 48201, USA
Mitogen-activated protein kinase phosphatase 1 regulates bone mass, osteoblast gene expression, and responsiveness to parathyroid hormone
Journal of Endocrinology
Mahalingam, CD;Datta, T;Patil, RV;Kreider, J;Bonfil, RD;Kirkwood, KL;Goldstein, SA;Abou-Samra, AB;Datta, NS;
2011
21852324
November 1st, 2011
United States
Division of Endocrinology, Department of Internal Medicine, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
Blood-brain barrier impairment in an animal model of MPS III B
PLOS ONE
Garbuzova-Davis, S;Louis, MK;Haller, EM;Derasari, HM;Rawls, AE;Sanberg, PR;
2011
21408219
March 7th, 2011
United States
College of Medicine, Center of Excellence for Aging & Brain Repair, University of South Florida, Tampa, Florida, United States of America
Neonatal periostin knockout mice are protected from hyperoxia-induced alveolar simplication
PLOS ONE
Bozyk, PD;Bentley, JK;Popova, AP;Anyanwu, AC;Linn, MD;Goldsmith, AM;Pryhuber, GS;Moore, BB;Hershenson, MB;
2012
22363622
February 24th, 2012
United States
Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
Neuromuscular junction defects in mice with mutation of dynein heavy chain 1
PLOS ONE
Courchesne, SL;Pazyra-Murphy, MF;Lee, DJ;Segal, RA;
2011
21346813
February 4th, 2011
United States
Department of Cancer Biology, Dana Farber Cancer Institute, Boston, Massachusetts, United States of America
The nicotinic receptor Alpha7 impacts the mouse lung response to LPS through multiple mechanisms
PLOS ONE
Enioutina, EY;Myers, EJ;Tvrdik, P;Hoidal, JR;Rogers, SW;Gahring, LC;
2015
25803612
March 25th, 2015
United States
Department of Internal Medicine, Division of Geriatrics, University of Utah School of Medicine, Salt Lake City, Utah, United States of America; Department of Pathology, Division of Microbiology and Immunology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America
Generation and Characterisation of a Pax8-CreERT2 Transgenic Line and a Slc22a6-CreERT2 Knock-In Line for Inducible and Specific Genetic Manipulation of Renal Tubular Epithelial Cells
PLOS ONE
Espana-Agusti, J;Zou, X;Wong, K;Fu, B;Yang, F;Tuveson, DA;Adams, DJ;Matakidou, A;
2016
26866916
February 12th, 2016
United Kingdom
Department of Oncology, University of Cambridge, CRUK Cambridge institute, Cambridge, United Kingdom
A neonatal model of intravenous Staphylococcus epidermidis infection in mice <24 h old enables characterization of early innate immune responses
PLOS ONE
Kronforst, KD;Mancuso, CJ;Pettengill, M;Ninkovic, J;Power Coombs, MR;Stevens, C;Otto, M;Mallard, C;Wang, X;Goldmann, D;Levy, O;
2012
22970147
September 12th, 2012
United States
Newborn Medicine, Boston Children's Hospital, Boston, Massachusetts, United States of America
Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis
PLOS ONE
May, SL;Zhou, Q;Lewellen, M;Carter, CM;Coffey, D;Highfill, SL;Bucher, CM;Matise, I;Morse, HC;O'Sullivan, MG;Schutten, M;Johnson, C;Bellgrau, D;Blazar, BR;Modiano, JF;
2014
24945807
June 20th, 2014
United States
Masonic Cancer Center, University of Minnesota, Minneapolis, Minnesota, United States of America; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St Paul, Minnesota, United States of America; Integrated Department of Immunology, School of Medicine, University of Colorado, Denver, Colorado, United States of America; University of Colorado Cancer Center, Aurora, Colorado, United States of America
Smad4 loss synergizes with TGFë± overexpression in promoting pancreatic metaplasia, PanIN development, and fibrosis
PLOS ONE
Garcia-Carracedo, D;Yu, CC;Akhavan, N;Fine, SA;Sch̦nleben, F;Maehara, N;Karg, DC;Xie, C;Qiu, W;Fine, RL;Remotti, HE;Su, GH;
2015
25803032
March 25th, 2015
United States
The Department of Pathology, Columbia University Medical Center, New York, New York, United States of America; Herbert Irving Comprehensive Cancer Center, Columbia University Medical Center, New York, New York, United States of America; Pancreas Center, Columbia University Medical Center, New York, New York, United States of America; Department of Otolaryngology and Head and Neck Surgery, Columbia University Medical Center, New York, New York, United States of America
CRX is a diagnostic marker of retinal and pineal lineage tumors
PLOS ONE
Santagata, S;Maire, CL;Idbaih, A;Geffers, L;Correll, M;Holton, K;Quackenbush, J;Ligon, KL;
2009
19936203
November 20th, 2009
United States
Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts, United States of America
Lamellipodin-Deficient Mice: A Model of Rectal Carcinoma
PLOS ONE
Miller, CL;Muthupalani, S;Shen, Z;Drees, F;Ge, Z;Feng, Y;Chen, X;Gong, G;Nagar, KK;Wang, TC;Gertler, FB;Fox, JG;
2016
27045955
April 6th, 2016
United States
Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, United States of America
Insulin and Leptin Signaling Interact in the Mouse Kiss1 Neuron during the Peripubertal Period
PLOS ONE
Qiu, X;Dao, H;Wang, M;Heston, A;Garcia, KM;Sangal, A;Dowling, AR;Faulkner, LD;Molitor, SC;Elias, CF;Hill, JW;
2015
25946091
May 7th, 2015
United States
Center for Diabetes and Endocrine Research, Department of Physiology and Pharmacology, University of Toledo College of Medicine, Toledo, Ohio, United States of America; Department of Obstetrics-Gynecology, University of Toledo College of Medicine, Toledo, Ohio, United States of America
Considerations in the identification of endogenous substrates for protein L-isoaspartyl methyltransferase: the case of synuclein
PLOS ONE
Morrison, GJ;Ganesan, R;Qin, Z;Aswad, DW;
2012
22905247
August 20th, 2012
United States
Department of Molecular Biology & Biochemistry, University of California Irvine, Irvine, California, United States of America
Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage
PLOS ONE
Shearn, CT;Orlicky, DJ;McCullough, RL;Jiang, H;Maclean, KN;Mercer, KE;Stiles, BL;Saba, LM;Ronis, MJ;Petersen, DR;
2016
27124661
April 29th, 2016
United States
Skaggs School of Pharmaceutical Sciences and Pharmacy, University of Colorado Anschutz Medical Campus, Aurora, CO, United States of America
Comparative Analysis of Pain Behaviours in Humanized Mouse Models of Sickle Cell Anemia
PLOS ONE
Lei, J;Benson, B;Tran, H;Ofori-Acquah, SF;Gupta, K;
2016
27494522
August 6th, 2016
United States
Vascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, Minnesota, United States of America
Isoaspartate accumulation in mouse brain is associated with altered patterns of protein phosphorylation and acetylation, some of which are highly sex-dependent
PLOS ONE
Qin, Z;Kaufman, RS;Khoury, RN;Khoury, MK;Aswad, DW;
2013
24224061
November 13th, 2013
United States
Department of Molecular Biology & Biochemistry, University of California Irvine, Irvine, California, United States of America
Generation and behavior characterization of CaMKIIë_ knockout mice
PLOS ONE
Bachstetter, AD;Webster, SJ;Tu, T;Goulding, DS;Haiech, J;Watterson, DM;Van Eldik, LJ;
2014
25127391
August 16th, 2014
United States
Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America; Department of Anatomy and Neurobiology, University of Kentucky, Lexington, Kentucky, United States of America
Parental diabetes: the Akita mouse as a model of the effects of maternal and paternal hyperglycemia in wildtype offspring
PLOS ONE
Grasemann, C;Devlin, MJ;Rzeczkowska, PA;Herrmann, R;Horsthemke, B;Hauffa, BP;Grynpas, M;Alm, C;Bouxsein, ML;Palmert, MR;
2012
23209676
December 4th, 2012
Germany
Kinderklinik II, Division of Paediatric Endocrinology, UK- Essen and The University of Duisburg-Essen, Essen, Germany
Digastric Muscle Phenotypes of the Ts65Dn Mouse Model of Down Syndrome
PLOS ONE
Glass, TJ;Connor, NP;
2016
27336944
June 24th, 2016
United States
Department of Surgery, University of Wisconsin, Madison, Wisconsin, United States of America
Rapamycin and chloroquine: the in vitro and in vivo effects of autophagy-modifying drugs show promising results in valosin containing protein multisystem proteinopathy
PLOS ONE
Nalbandian, A;Llewellyn, KJ;Nguyen, C;Yazdi, PG;Kimonis, VE;
2015
25884947
April 18th, 2015
United States
Department of Pediatrics, Division of Genetics and Metabolism, University of California, Irvine, California, United States of America; Sue and Bill Gross Stem Cell Center, University of California, Irvine, California, United States of America
A Fine Balance of Dietary Lipids Improves Pathology of a Murine Model of VCP-Associated Multisystem Proteinopathy
PLOS ONE
Llewellyn, KJ;Walker, N;Nguyen, C;Tan, B;BenMohamed, L;Kimonis, VE;Nalbandian, A;
2015
26134519
July 3rd, 2015
United States
Department of Pediatrics, Division of Genetics and Genomics Medicine, University of California Irvine, Irvine, CA, 92697, United States of America; Sue and Bill Gross Stem Institute, University of California Irvine, Irvine, CA, 92697, United States of America
Cholecystokinin: an excitatory modulator of mitral/tufted cells in the mouse olfactory bulb
PLOS ONE
Ma, J;Dankulich-Nagrudny, L;Lowe, G;
2013
23691163
May 21st, 2013
United States
Monell Chemical Senses Center, Philadelphia, Pennsylvania, United States of America
Mechanism of testosterone deficiency in the transgenic sickle cell mouse
PLOS ONE
Musicki, B;Zhang, Y;Chen, H;Brown, TR;Zirkin, BR;Burnett, AL;
2015
26023917
May 30th, 2015
United States
The James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins School of Medicine, Baltimore, Maryland, United States of America
Novel marker for the onset of frontotemporal dementia: early increase in activity-dependent neuroprotective protein (ADNP) in the face of Tau mutation
PLOS ONE
Schirer, Y;Malishkevich, A;Ophir, Y;Lewis, J;Giladi, E;Gozes, I;
2014
24489906
February 3rd, 2014
Israel
The Adams Super Center for Brain Studies, The Lily and Avraham Gildor Chair for the Investigation of Growth Factors, The Elton Laboratory for Neuroendocrinology, Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine and Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel
Intrinsic susceptibility MRI identifies tumors with ALKF1174L mutation in genetically-engineered murine models of high-risk neuroblastoma
PLOS ONE
Jamin, Y;Glass, L;Hallsworth, A;George, R;Koh, DM;Pearson, AD;Chesler, L;Robinson, SP;
2014
24667968
March 26th, 2014
United Kingdom
Division of Radiotherapy and Imaging, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, United Kingdom
The effects of C75, an inhibitor of fatty acid synthase, on sleep and metabolism in mice
PLOS ONE
Pellinen, J;Szentirmai, Ìä;
2012
22348016
February 20th, 2012
United States
Washington, Wyoming, Alaska, Montana and Idaho, Medical Education Program, Washington State University, Spokane, Washington, United States of America
A reinforcing circuit action of extrasynaptic GABAA receptor modulators on cerebellar granule cell inhibition
PLOS ONE
Santhakumar, V;Meera, P;Karakossian, MH;Otis, TS;
2013
23977374
August 26th, 2013
United States
Department of Neurobiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, United States of America
Cranial irradiation alters the brain's microenvironment and permits CCR2+ macrophage infiltration
PLOS ONE
Morganti, JM;Jopson, TD;Liu, S;Gupta, N;Rosi, S;
2014
24695541
April 3rd, 2014
United States
Brain and Spinal Injury Center, University of California San Francisco, San Francisco, California, United States of America; Departments of Physical Therapy and Rehabilitation Science, University of California San Francisco, San Francisco, California, United States of America; Neurological Surgery, University of California San Francisco, San Francisco, California, United States of America
Deficiency in p38ë_ MAPK fails to inhibit cytokine production or protect neurons against inflammatory insult in in vitro and in vivo mouse models
PLOS ONE
Xing, B;Bachstetter, AD;Van Eldik, LJ;
2013
23457629
March 4th, 2013
United States
Sanders-Brown Center on Aging, University of Kentucky, Lexington, Kentucky, United States of America
Hilar somatostatin interneurons contribute to synchronized GABA activity in an in vitro epilepsy model
PLOS ONE
Grosser, S;Queenan, BN;Lalchandani, RR;Vicini, S;
2014
24465989
January 27th, 2014
United States
Department of Pharmacology and Physiology, Georgetown University, Washington, District of Columbia, United States of America ; Interdisciplinary Program in Neuroscience, Georgetown University, Washington, District of Columbia, United States of America
RDH10 oxidation of Vitamin A is a critical control step in synthesis of retinoic acid during mouse embryogenesis
PLOS ONE
Sandell, LL;Lynn, ML;Inman, KE;McDowell, W;Trainor, PA;
2012
22319578
February 9th, 2012
United States
Stowers Institute for Medical Research, Kansas City, Missouri, United States of America
7 Nicotinic receptor-mediated astrocytic gliotransmitter release: A effects in a preclinical Alzheimer's mouse model
PLOS ONE
Pirttimaki, TM;Codadu, NK;Awni, A;Pratik, P;Nagel, DA;Hill, EJ;Dineley, KT;Parri, HR;
2013
November 28th, 2013
United States
School of Life and Health Sciences, Aston University
Comprehensive analysis of ultrasonic vocalizations in a mouse model of fragile X syndrome reveals limited, call type specific deficits
PLOS ONE
Roy, S;Watkins, N;Heck, D;
2012
22984567
September 17th, 2012
United States
Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee, United States of America
GPR40 and GPR120 fatty acid sensors are critical for postoral but not oral mediation of fat preferences in the mouse
American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Sclafani, A;Zukerman, S;Ackroff, K;
2013
24154510
December 15th, 2013
United States
Department of Psychology, Brooklyn College, City University of New York, Brooklyn, New York, and
P2X7 receptors in body temperature, locomotor activity, and brain mRNA and lncRNA responses to sleep deprivation
American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Davis, CJ;Taishi, P;Honn, KA;Koberstein, JN;Krueger, JM;
2016
27707719
December 1st, 2016
United States
Elson S. Floyd College of Medicine, Department of Biomedical Sciences, Washington State University-Spokane, Spokane, Washington
Sugar-induced cephalic-phase insulin release is mediated by a T1r2+T1r3-independent taste transduction pathway in mice
American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Glendinning, JI;Stano, S;Holter, M;Azenkot, T;Goldman, O;Margolskee, RF;Vasselli, JR;Sclafani, A;
2015
26157055
September 1st, 2015
United States
Department of Biology, Barnard College, Columbia University, New York, New York
Restricted feeding-induced sleep, activity, and body temperature changes in normal and preproghrelin-deficient mice
American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Szentirmai, E;KapÃŒÃs, L;Sun, Y;Smith, RG;Krueger, JM;
2010
19939974
February 1st, 2010
United States
WWAMI Medical Education Program, Washington State Univ., Spokane, P.O. Box 1495, Spokane, WA 99210-1495, USA
Spontaneous sleep and homeostatic sleep regulation in ghrelin knockout mice
American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Szentirmai, E;KapÃŒÃs, L;Sun, Y;Smith, RG;Krueger, JM;
2007
17409264
July 1st, 2007
United States
Department of Veterinary and Comparative Anatomy, Pharmacology and Physiology, Program in Neuroscience, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6520, USA
SOD1-G93A mice exhibit muscle-fiber-type-specific decreases in glucose uptake in the absence of whole-body changes in metabolism
Neuro-degenerative Diseases
Smittkamp, SE;Morris, JK;Bomhoff, GL;Chertoff, ME;Geiger, PC;Stanford, JA;
2014
24021858
December 20th, 2014
United States
Department of Molecular and Integrative Physiology, University of Kansas Medical Center, Kansas City, Kans., USA
Effects of stimulus salience on touchscreen serial reversal learning in a mouse model of fragile X syndrome
Behavioral Brain Research
Dickson, PE;Corkill, B;McKimm, E;Miller, MM;Calton, MA;Goldowitz, D;Blaha, CD;Mittleman, G;
2013
23747611
September 1st, 2013
United States
The Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA
Sustained attention in mice: expanding the translational utility of the SAT by incorporating the Michigan Controlled Access Response Port (MICARP)
Behavioral Brain Research
St Peters, M;Cherian, AK;Bradshaw, M;Sarter, M;
2011
21888929
December 1st, 2011
United States
Department of Psychology, University of Michigan, Ann Arbor, MI 48109-8862, United States
A novel role for the immunophilin FKBP52 in motor coordination
Behavioral Brain Research
Young, MJ;Geiszler, PC;Pardon, MC;
2016
27418439
October 15th, 2016
United Kingdom
University of Nottingham Medical School, School of Life Sciences, Neuroscience group, Queen's Medical Centre, Nottingham NG7 2UH United Kingdom
Neuronal nitric oxide synthase and NADPH oxidase interact to affect cognitive, affective, and social behaviors in mice
Behavioral Brain Research
Walton, JC;Selvakumar, B;Weil, ZM;Snyder, SH;Nelson, RJ;
2013
23948215
November 1st, 2013
United States
Department of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH 43210, USA
Measures of bulbar and spinal motor function, muscle innervation, and mitochondrial function in ALS rats
Behavioral Brain Research
Smittkamp, SE;Spalding, HN;Brown, JW;Gupte, AA;Chen, J;Nishimune, H;Geiger, PC;Stanford, JA;
2010
20211206
July 29th, 2010
United States
Department of Molecular & Integrative Physiology, University of Kansas Medical Center, Kansas City, KS 66160, United States
Spatial frequency threshold and contrast sensitivity of an optomotor behavior are impaired in the Ins2Akita mouse model of diabetes
Behavioral Brain Research
Akimov, NP;RenterÌ_a, RC;
2012
21963766
January 15th, 2012
United States
Department of Physiology and Center for Biomedical Neuroscience, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, United States
Molecular and behavioral profiling of Dbx1-derived neurons in the arcuate, lateral and ventromedial hypothalamic nuclei
Neural Development
Sokolowski, K;Tran, T;Esumi, S;Kamal, Y;Oboti, L;Lischinsky, J;Goodrich, M;Lam, A;Carter, M;Nakagawa, Y;Corbin, JG;
2016
27209204
May 21st, 2016
United States
Center for Neuroscience Research, Children's National Medical Center, 111 Michigan Avenue, NW, Washington, 20010, DC, USA
Common and unique genetic interactions of the poly(ADP-ribose) polymerases PARP1 and PARP2 with DNA double-strand break repair pathways
DNA Repair
Ghosh, R;Roy, S;Kamyab, J;Dantzer, F;Franco, S;
2016
27373144
September 1st, 2016
United States
Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, MD 21287, United States
In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice
Drug Metabolism and Disposition
Yasuda, K;Cline, C;Lin, YS;Scheib, R;Ganguly, S;Thirumaran, RK;Chaudhry, A;Kim, RB;Schuetz, EG;
2015
26281846
November 1st, 2015
United States
Department of Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, Tennessee (K.Y., C.C., R.S., S.G., R.K.T., A.C., E.G.S.); Department of Medicine, Division of Clinical Pharmacology, University of Western Ontario, London, Ontario, Canada (R.B.K.); and Department of Pharmaceutics, The University of Washington, Seattle, Washington (Y.S.L.)
Pharmacokinetics of oral D-serine in D-amino acid oxidase knockout mice
Drug Metabolism and Disposition
Rais, R;Thomas, AG;Wozniak, K;Wu, Y;Jaaro-Peled, H;Sawa, A;Strick, CA;Engle, SJ;Brandon, NJ;Rojas, C;Slusher, BS;Tsukamoto, T;
2012
22837388
November 1st, 2012
United States
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
Separation of function for classical and ganglion cell photoreceptors with respect to circadian rhythm entrainment and induction of photosomnolence
Neuroscience
Morin, LP;Studholme, KM;
2011
21985934
December 29th, 2011
United States
Department of Psychiatry, Stony Brook University Medical Center, Stony Brook, NY, USA
Activation of the Wnt/ë_-catenin signaling cascade after traumatic nerve injury
Neuroscience
Kurimoto, S;Jung, J;Tapadia, M;Lengfeld, J;Agalliu, D;Waterman, M;Mozaffar, T;Gupta, R;
2015
25743255
May 21st, 2015
United States
Department of Orthopaedic Surgery, University of California, Irvine, CA 92697, USA; Department of Hand Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-Cho, Showa-Ku, Nagoya 466-8550, Japan
Distinct mechanisms of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine resistance revealed by transcriptome mapping in mouse striatum
Neuroscience
Pattarini, R;Rong, Y;Qu, C;Morgan, JI;
2008
18675323
September 1st, 2008
United States
Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN 38105-3678, USA
Nuclear Thioredoxin-1 Overexpression Attenuates Alcohol-Mediated Nrf2 Signaling and Lung Fibrosis
Alcoholism Clinical and Experimental Research
Sueblinvong, V;Mills, ST;Neujahr, DC;Go, YM;Jones, DP;Guidot, DM;
2016
27436123
September 1st, 2016
United States
Division of Pulmonary, Allergy & Critical Care, Department of Medicine, Atlanta, Georgia
Effects of Gabra2 Point Mutations on Alcohol Intake: Increased Binge-Like and Blunted Chronic Drinking by Mice
Alcoholism Clinical and Experimental Research
Newman, EL;Gunner, G;Huynh, P;Gachette, D;Moss, SJ;Smart, TG;Rudolph, U;DeBold, JF;Miczek, KA;
2016
27717041
November 1st, 2016
United States
Department of Psychology, Tufts University, Medford, Massachusetts. , ELnewman@gmail.com
Galanin knockout mice show disturbances in ethanol consumption and expression of hypothalamic peptides that stimulate ethanol intake
Alcoholism Clinical and Experimental Research
Karatayev, O;Baylan, J;Weed, V;Chang, S;Wynick, D;Leibowitz, SF;
2010
19860804
January 1st, 2010
United States
Laboratory of Behavioral Neurobiology, Rockefeller University, New York, New York, USA
Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication
Virology
Hodgson, AJ;Hyser, JM;Keasler, VV;Cang, Y;Slagle, BL;
2012
22342275
April 25th, 2012
United States
Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX 77030, USA
Fragile X mental retardation protein regulates olfactory sensitivity but not odorant discrimination
Chemical Senses
Schilit Nitenson, A;Stackpole, EE;Truszkowski, TL;Midroit, M;Fallon, JR;Bath, KG;
2015
25917509
June 1st, 2015
United States
Department of Neuroscience, Brown University, 185 Meeting Street, Providence, RI 02912, USA, Department of Cognitive, Linguistic and Psychological Sciences, Brown University, 190 Thayer Street, Providence, RI 02912, USA
Salty taste deficits in CALHM1 knockout mice
Chemical Senses
Tordoff, MG;Ellis, HT;Aleman, TR;Downing, A;Marambaud, P;Foskett, JK;Dana, RM;McCaughey, SA;
2014
24846212
July 1st, 2014
United States
Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104, USA
Normal Taste Acceptance and Preference of PANX1 Knockout Mice
Chemical Senses
Tordoff, MG;Aleman, TR;Ellis, HT;Ohmoto, M;Matsumoto, I;Shestopalov, VI;Mitchell, CH;Foskett, JK;Poole, RL;
2015
25987548
September 1st, 2015
United States
Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104, USA
Heightened avidity for trisodium pyrophosphate in mice lacking Tas1r3
Chemical Senses
Tordoff, MG;Aleman, TR;McCaughey, SA;
2015
25452580
January 1st, 2015
United States
Monell Chemical Senses Center, 3500 Market Street, Philadelphia, PA 19104, USA and
Ectopic POU5F1 in the male germ lineage disrupts differentiation and spermatogenesis in mice
Reproduction
Zheng, Y;Phillips, LJ;Hartman, R;An, J;Dann, CT;
2016
27486267
October 1st, 2016
United States
Department of ChemistryIndiana University, Bloomington, Indiana, USA
Comprehensive motor testing in Fmr1-KO mice exposes temporal defects in oromotor coordination
Behavioral Neuroscience
Roy, S;Zhao, Y;Allensworth, M;Farook, MF;LeDoux, MS;Reiter, LT;Heck, DH;
2011
22004265
December 1st, 2011
United States
Department of Anatomy and Neurobiology, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
Aryl hydrocarbon receptor knockout rats are insensitive to the pathological effects of repeated oral exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin
Journal of Applied Toxicology
Harrill, JA;Layko, D;Nyska, A;Hukkanen, RR;Manno, RA;Grassetti, A;Lawson, M;Martin, G;Budinsky, RA;Rowlands, JC;Thomas, RS;
2016
26278112
June 1st, 2016
United States
The Hamner Institutes for Health Sciences, Institute for Chemical Safety Sciences, Research Triangle Park, NC, 27709, USA
Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis
Journal of Sexual Medicine
Musicki, B;Bivalacqua, TJ;Champion, HC;Burnett, AL;
2014
24251665
February 1st, 2014
United States
The James Buchanan Brady Urological Institute, Department of Urology, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Post-translational inactivation of endothelial nitric oxide synthase in the transgenic sickle cell mouse penis
Journal of Sexual Medicine
Musicki, B;Champion, HC;Hsu, LL;Bivalacqua, TJ;Burnett, AL;
2011
21143412
February 1st, 2011
United States
The Johns Hopkins University, Department of Urology, Baltimore, MD 21287, USA
Extracellular sodium and potassium levels modulate cardiac conduction in mice heterozygous null for the Connexin43 gene
Pflugers Archiv - European Journal of Physiology
George, SA;Sciuto, KJ;Lin, J;Salama, ME;Keener, JP;Gourdie, RG;Poelzing, S;
2015
25771952
November 1st, 2015
United States
Department of Biomedical Engineering and Mechanics, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA
Astrocytic group I mGluR-dependent potentiation of astrocytic glutamate and potassium uptake
Journal of Neurophysiology
Devaraju, P;Sun, MY;Myers, TL;Lauderdale, K;Fiacco, TA;
2013
23427307
May 1st, 2013
United States
Department of Cell Biology and Neuroscience, University of California, Riverside, CA, USA
pigk Mutation underlies macho behavior and affects Rohon-Beard cell excitability
Journal of Neurophysiology
Carmean, V;Yonkers, MA;Tellez, MB;Willer, JR;Willer, GB;Gregg, RG;Geisler, R;Neuhauss, SC;Ribera, AB;
2015
26133798
August 1st, 2015
United States
Neuroscience Program, University of Colorado Anschutz Medical Campus, Aurora, Colorado; Department of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, Colorado
PACAP modulation of calcium ion activity in developing granule cells of the neonatal mouse olfactory bulb
Journal of Neurophysiology
Irwin, M;Greig, A;Tvrdik, P;Lucero, MT;
2015
25475351
February 15th, 2015
United States
Department of Physiology, University of Utah School of Medicine, Salt Lake City, Utah; Interdepartmental Neuroscience Program, University of Utah School of Medicine, Salt Lake City, Utah; and Department of Neuroscience and Physiology, American University of the Caribbean, Cupecoy, Sint Maarten, Netherlands Antilles
Impact of inhibitory constraint of interneurons on neuronal excitability
Journal of Neurophysiology
Lee, V;Maguire, J;
2013
24027099
December 1st, 2013
United States
Medical Scientist Training Program and Graduate Program in Neuroscience, Sackler School of Graduate Biomedical Sciences, Tufts University, Boston, Massachusetts; and
Intragastric fat self-administration is impaired in GPR40/120 double knockout mice
Physiology and Behavior
Sclafani, A;Touzani, K;Ackroff, K;
2015
25911263
August 1st, 2015
United States
Brooklyn College of CUNY, Brooklyn, NY, USA
MCH receptor deletion does not impair glucose-conditioned flavor preferences in mice
Physiology and Behavior
Sclafani, A;Adamantidis, A;Ackroff, K;
2016
27195455
September 1st, 2016
United States
Department of Psychology, Brooklyn College of the City University of New York, Brooklyn, NY, USA; Behavioral and Cognitive Neuroscience Cluster, Psychology Doctoral Program, The Graduate School, City University of New York, New York, NY, USA
Ghrelin signaling is not essential for sugar or fat conditioned flavor preferences in mice
Physiology and Behavior
Sclafani, A;Touzani, K;Ackroff, K;
2015
26003495
October 1st, 2015
United States
Brooklyn College of CUNY, Brooklyn, NY, USA
Macronutrient selection by seven inbred mouse strains and three taste-related knockout strains
Physiology and Behavior
Tordoff, MG;Downing, A;Voznesenskaya, A;
2014
24912134
August 1st, 2014
United States
Monell Chemical Senses Center, Philadelphia, PA 19194, USA
Sucrose-conditioned flavor preferences in sweet ageusic T1r3 and Calhm1 knockout mice
Physiology and Behavior
Sclafani, A;Marambaud, P;Ackroff, K;
2014
24384370
March 14th, 2014
United States
Department of Psychology, Brooklyn College, City University of New York, Brooklyn, NY 11210, USA
Retinal macroglia changes in a triple transgenic mouse model of Alzheimer's disease
Experimental Eye Research
Edwards, MM;RodrÌ_guez, JJ;Gutierrez-Lanza, R;Yates, J;Verkhratsky, A;Lutty, GA;
2014
25149907
October 1st, 2014
United States
Wilmer Eye Institute, Johns Hopkins Hospital, M023 Smith Building, 400 N. Broadway, Baltimore, MD 21287, USA
Intact Toll-like receptor 9 signaling in neutrophils modulates normal thrombogenesis in mice
Journal of Vasuclar Surgery
El-Sayed, OM;Dewyer, NA;Luke, CE;Elfline, M;Laser, A;Hogaboam, C;Kunkel, SL;Henke, PK;
2016
26482993
November 1st, 2016
United States
Department of Vascular Surgery, University of Michigan Medical School, Ann Arbor, Mich
Morphine-induced antinociception and reward in humanized mice expressing the mu opioid receptor A118G polymorphism
Brain Research Bulletin
Henderson-Redmond, AN;Yuill, MB;Lowe, TE;Kline, AM;Zee, ML;Guindon, J;Morgan, DJ;
2016
26521067
May 1st, 2016
United States
Department of Pharmacology and Neuroscience, Texas Tech University Health Science Center, Lubbock, TX 79430, United States
Altered gamma oscillations during pregnancy through loss of ë« subunit-containing GABA(A) receptors on parvalbumin interneurons
Frontiers in Neural Circuits
Ferando, I;Mody, I;
2013
24062647
September 24th, 2013
United States
Department of Neurology, The David Geffen School of Medicine, University of California Los Angeles, CA 90095-733522, USA
Severe drug-induced repetitive behaviors and striatal overexpression of VAChT in ChAT-ChR2-EYFP BAC transgenic mice
Frontiers in Neural Circuits
Crittenden, JR;Lacey, CJ;Lee, T;Bowden, HA;Graybiel, AM;
2014
24904300
June 6th, 2014
United States
Department of Brain and Cognitive Sciences and McGovern Institute for Brain Research, Massachusetts Institute of Technology Cambridge, MA, USA
Distinct roles of synaptic and extrasynaptic GABAAreceptors in striatal inhibition dynamics
Frontiers in Neural Circuits
Luo, R;Partridge, JG;Vicini, S;
2013
24324406
December 10th, 2013
United States
Department of Pharmacology and Physiology, Georgetown University School of Medicine Washington, DC, USA
Cerebellar Nuclei Neurons Show Only Small Excitatory Responses to Optogenetic Olivary Stimulation in Transgenic Mice: In Vivo and In Vitro Studies
Frontiers in Neural Circuits
Lu, H;Yang, B;Jaeger, D;
2016
27047344
April 6th, 2016
United States
Department of Biomedical Sciences, Philadelphia College of Osteopathic Medicine-Georgia CampusSuwannee, GA, USA; Department of Biology, Emory UniversityAtlanta, GA, USA
Conditional knockout of myocyte focal adhesion kinase abrogates ischemic preconditioning in adult murine hearts
Journal of American Heart Association
Perricone, AJ;Bivona, BJ;Jackson, FR;Vander Heide, RS;
2013
24080910
September 30th, 2013
United States
Department of Pathology, Louisiana State University Health Sciences Center, New Orleans, LA
Reorganization of circuits underlying cerebellar modulation of prefrontal cortical dopamine in mouse models of autism spectrum disorder
Cerebellum
Rogers, TD;Dickson, PE;McKimm, E;Heck, DH;Goldowitz, D;Blaha, CD;Mittleman, G;
2013
23436049
August 1st, 2013
United States
Department of Psychology, University of Memphis, Memphis, TN 38152-6400, USA
E-prostanoid 2 receptor signaling suppresses lung innate immunity against Streptococcus pneumoniae
Prostaglandins Other Lipid Mediators
Aronoff, DM;Bergin, IL;Lewis, C;Goel, D;O'Brien, E;Peters-Golden, M;Mancuso, P;
2012
22575745
May 1st, 2012
United States
Divisions of Infectious Diseases, The University of Michigan, Ann Arbor, MI 48109-5680, United States
Non-invasive quantification of brain tumor-induced astrogliosis
BMC Neuroscience
Lee, J;Borboa, AK;Baird, A;Eliceiri, BP;
2011
21247490
January 19th, 2011
United States
Department of Surgery, University of California San Diego, San Diego, CA, USA
Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis
Brain Research
Lopez, AM;Chuang, JC;Posey, KS;Turley, SD;
2017
27789278
January 1st, 2017
United States
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Long-term improvements in sensory inhibition with gestational choline supplementation linked to 7 nicotinic receptors through studies in Chrna7 null mutation mice
Brain Research
Stevens, KE;Choo, KS;Stitzel, JA;Marks, MJ;Adams, CE;
2014
March 13th, 2014
United States
Medical Research Service, Veterans Affairs Medical Center, Denver, CO, USA
Taste dysfunction in BTBR mice due to a mutation of Itpr3, the inositol triphosphate receptor 3 gene
Physiological Genomics
Tordoff, MG;Ellis, HT;
2013
23859941
September 16th, 2013
United States
Monell Chemical Senses Center, Philadelphia, Pennsylvania
Involvement of T1R3 in calcium-magnesium taste
Physiological Genomics
Tordoff, MG;Shao, H;AlarcÌ_n, LK;Margolskee, RF;Mosinger, B;Bachmanov, AA;Reed, DR;McCaughey, S;
2008
18593862
August 15th, 2008
United States
Monell Chemical Senses Center, Philadelphia, Pennsylvania 19104-3308, USA
Lipoprotein(a) and vitamin C impair development of breast cancer tumors in Lp(a)+; Gulo-/- mice
International Journal of Oncology
Cha, J;Roomi, MW;Kalinovsky, T;Niedzwiecki, A;Rath, M;
2016
27573077
September 1st, 2016
United States
Dr. Rath Research Institute, Santa Clara, CA 95050, USA
Ascorbate supplementation inhibits growth and metastasis of B16FO melanoma and 4T1 breast cancer cells in vitamin C-deficient mice
International Journal of Oncology
Cha, J;Roomi, MW;Ivanov, V;Kalinovsky, T;Niedzwiecki, A;Rath, M;
2013
23175106
January 1st, 2013
United States
Dr Rath Research Institute, Santa Clara, CA 95050, USA
Inhibition of neuronal p38ë±, but not p38ë_ MAPK, provides neuroprotection against three different neurotoxic insults
Journal of Molecular Neuroscience
Xing, B;Bachstetter, AD;Van Eldik, LJ;
2015
25012593
February 1st, 2015
United States
Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY, 40536, USA
Abstracts of the 10th International Symposium on VIP-PACAP and Related Peptides. December 13-16, 2011. Eilat, Israel
Journal of Molecular Neuroscience
Unknown, ;
2012
22144041
November 1st, 2012
Israel
The Israel Society for Neuroscience Meeting
Lentiviral-based approach for the validation of cancer therapeutic targets in vivo
BioTechniques
Ambrogio, C;Stern, P;Scuoppo, C;Kranz, H;Barbacid, M;SantamarÌ_a, D;
2014
25312087
October 1st, 2014
Spain
Molecular Oncology Programme, Centro Nacional de Investigaciones OncolÌ_gicas (CNIO), Spanish National Cancer Research Center, Madrid, Spain
Intravital live cell triggered imaging system reveals monocyte patrolling and macrophage migration in atherosclerotic arteries
Journal of Biomedical Optics
McArdle, S;Chodaczek, G;Ray, N;Ley, K;
2015
25710308
February 1st, 2015
United States
La Jolla Institute, 9420 Athena Circle, La Jolla, California 92037, United States
Knockout of p11 attenuates the acquisition and reinstatement of cocaine conditioned place preference in male but not in female mice
Synapse
Thanos, PK;Malave, L;Delis, F;Mangine, P;Kane, K;Grunseich, A;Vitale, M;Greengard, P;Volkow, ND;
2016
26990537
July 1st, 2016
United States
Behavioral Neuropharmacology and Neuroimaging Laboratory on Addictions, Research Institute on Addictions, University at Buffalo, Buffalo, New York
Evaluation of [Ã¥_‰ÂüF]PFH PET renography to predict future disease progression in a rat model of autosomal dominant polycystic kidney disease
Nuclear Medicine and Biology
Pathuri, G;Hedrick, AF;Awasthi, V;Cowley, BD;Gali, H;
2016
26702780
January 1st, 2016
United States
Department of Pharmaceutical Sciences, College of Pharmacy, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA
Quantification of pain in sickle mice using facial expressions and body measurements
Blood Cells, Molecules, and Diseases
Mittal, A;Gupta, M;Lamarre, Y;Jahagirdar, B;Gupta, K;
2016
26852657
March 1st, 2016
United States
Vascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN, USA
Utrophin suppresses low frequency oscillations and coupled gating of mechanosensitive ion channels in dystrophic skeletal muscle
Channels (Austin)
Lansman, JB;
2015
25941878
June 13th, 2015
United States
a Department of Cellular and Molecular Pharmacology ; School of Medicine; University of California San Francisco; San Francisco , CA USA
A progressive translational mouse model of human valosin-containing protein disease: the VCP(R155H/+) mouse
Muscle Nerve
Nalbandian, A;Llewellyn, KJ;Badadani, M;Yin, HZ;Nguyen, C;Katheria, V;Watts, G;Mukherjee, J;Vesa, J;Caiozzo, V;Mozaffar, T;Weiss, JH;Kimonis, VE;
2013
23169451
February 1st, 2013
United States
Department of Pediatrics, Division of Genetics and Metabolism, 2501 Hewitt Hall, University of California, Irvine, Irvine, California 92696, USA
Circadian rhythmicity in serotonin transporter knockout mice
Life Sciences
Pang, RD;Holschneider, DP;Miller, JD;
2012
22884802
October 1st, 2012
United States
Graduate Program in Neuroscience, University of Southern California, CA 90033, United States
Protection against vascular leak in neprilysin transgenic mice with complexåÊoverexpressionåÊpattern
Transgenic Research
Wick, MJ;Loomis, ZL;Harral, JW;Le, M;Wehling, CA;Miller, YE;Dempsey, EC;
2016
27369050
December 1st, 2016
United States
Cardiovascular Pulmonary Research Laboratory, University of Colorado Denver, RC-2, Box B-133, 12700 E. 19th Ave., Aurora, CO, 80045, USA
A germline-competent embryonic stem cell line from NOD.Cg-Prkdc ( scid ) Il2rg ( tm1Wjl )/SzJ (NSG) mice
Transgenic Research
Landel, CP;Dunlap, J;Patton, JB;Manser, T;
2013
22767020
February 1st, 2013
United States
Department of Microbiology and Immunology, Thomas Jefferson University, 233 S. 10th St, Philadelphia, PA 19107, USA
Effects of SB-269970, a 5-HT7 receptor antagonist, in mouse models predictive of antipsychotic-like activity
Behavioral Pharmacology
Galici, R;Boggs, JD;Miller, KL;Bonaventure, P;Atack, JR;
2008
18332680
March 1st, 2008
United States
Johnson & Johnson Pharmaceutical Research and Development, LLC, 3210 Merryfield Row, San Diego, CA 92121, USA
Inducible cell labeling and lineage tracking during fracture repair
Development, Growth, and Differentiation
Seime, T;Kolind, M;Mikulec, K;Summers, MA;Cantrill, L;Little, DG;Schindeler, A;
2015
25389084
January 1st, 2015
Australia
Department of Orthopaedic Research & Biotechnology, The Children's Hospital at Westmead, Locked Bag 4001, Westmead, Sydney, NSW, 2145, Australia; MCI Management Center Innsbruck, A-6020 Innsbruck, Austria
Global gene expression profiling in R155H knock-in murine model of VCP disease
Clinical Transltional Science
Nalbandian, A;Ghimbovschi, S;Wang, Z;Knoblach, S;Llewellyn, KJ;Vesa, J;Hoffman, EP;Kimonis, VE;
2015
25388089
February 1st, 2015
United States
Department of Pediatrics, Division of Genetics and Metabolism, University of California-Irvine, Irvine, California, USA
ZASC1 knockout mice exhibit an early bone marrow-specific defect in murine leukemia virus replication
Virology Journal
Seidel, S;Bruce, J;Leblanc, M;Lee, KF;Fan, H;Ahlquist, P;Young, JA;
2013
23617998
April 24th, 2013
United States
Nomis Center for Immunobiology and Microbial Pathogenesis, The Salk Institute for Biological Studies, La Jolla, CA, USA
Anticonvulsant effects of the selective melatonin receptor agonist ramelteon - Epilepsy and Behavior
Anticonvulsant effects of the selective melatonin receptor agonist ramelteon
Epilepsy and Behavior
Fenoglio-Simeone, K;Mazarati, A;Sefidvash-Hockley, S;Shin, D;Wilke, J;Milligan, H;Sankar, R;Rho, JM;Maganti, R;
2009
19682955
September 1st, 2009
United States
Creighton University School of Medicine, Omaha, NE, USA
Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure
American Journal of Medical Genetics Part A
Rogers, SW;Tvrdik, P;Capecchi, MR;Gahring, LC;
2012
22473653
May 1st, 2012
United States
Salt Lake City VA Geriatric Research, Education and Clinical Center, Salt Lake City, Utah, USA
Megaesophagus in a line of transgenic rats: a model of achalasia
Veterinary Pathology
Pang, J;Borjeson, TM;Muthupalani, S;Ducore, RM;Carr, CA;Feng, Y;Sullivan, MP;Cristofaro, V;Luo, J;Lindstrom, JM;Fox, JG;
2014
24457157
November 1st, 2014
United States
Division of Comparative Medicine, Massachusetts Institute of Technology, Cambridge, MA, USA
Increased intake of ethanol and dietary fat in galanin overexpressing mice
Alcohol
Karatayev, O;Baylan, J;Leibowitz, SF;
2009
20004335
December 1st, 2009
United States
Laboratory of Behavioral Neurobiology, The Rockefeller University, 1230 York Avenue, New York, NY 10065, USA
Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice
Regulatory Peptides
Longo, KA;Charoenthongtrakul, S;Giuliana, DJ;Govek, EK;McDonagh, T;Qi, Y;DiStefano, PS;Geddes, BJ;
2008
18453014
October 1st, 2008
United States
Elixir Pharmaceuticals, Inc., 12 Emily St., Cambridge, MA 02139, United States
Bacterial load and inflammation in fetal tissues is not dependent on IL-17a or IL-22 in 10-14 day pregnant mice infected with Listeria monocytogenes
Microbial Pathogenesis
Poulsen, KP;Faith, NG;Steinberg, H;Czuprynski, CJ;
2013
23178254
March 1st, 2013
United States
Department of Clinical Sciences, College of Veterinary Medicine, Oregon State University, 700 SW 30th Street, Corvallis, OR 97331, USA
Multiple ERbeta antisera label in ERbeta knockout and null mouse tissues
Journal of Neuroscience Methods
Snyder, MA;Smejkalova, T;Forlano, PM;Woolley, CS;
2010
20170675
May 15th, 2010
United States
Department of Neurobiology and Physiology, Northwestern University, 2205 Tech Drive, Evanston, IL 60208, USA
Prediction of death in the SMNëÓ7 mouse model of spinal muscular atrophy: insight into disease stage and progression
Journal of Neuroscience Methods
El-Khodor, BF;Cirillo, K;Beltran, JA;Mushlin, R;Winberg, ML;Charney, R;Chomicova, O;Marino, T;Ramboz, S;
2012
22750651
August 15th, 2012
United States
PsychoGenics Inc., 765 Old Sawmill River Road, Tarrytown, NY 10591, United States
Activation of the NLRP3 Inflammasome Is Associated with Valosin-Containing Protein Myopathy
Inflammation
Nalbandian, A;Khan, AA;Srivastava, R;Llewellyn, KJ;Tan, B;Shukr, N;Fazli, Y;Kimonis, VE;BenMohamed, L;
2016
27730320
October 11th, 2016
United States
Laboratory of Cellular and Molecular Immunology, Gavin Herbert Institute, School of Medicine, University of California Irvine, Irvine, CA, 92697, USA
Attenuated Salmonella enterica Typhimurium reduces tumor burden in an autochthonous breast cancer model
Anticancer Research
Drees, J;Mertensotto, M;Liu, G;Panyam, J;Leonard, A;Augustin, L;Schottel, J;Saltzman, D;
2015
25667465
February 1st, 2015
United States
Department of Surgery, University of Minnesota, Minneapolis, MN, U.S.A
Maneb causes pro-oxidant effects in the hippocampus of Nrf2 knockout mice
Environ.mental Toxicology and Pharmacology
Kurzatkowski, DM;Trombetta, LD;
2013
23764462
September 1st, 2013
United States
Department of Pharmaceutical Sciences, St. John's University, 8000 Utopia Parkway, Queens, NY 11439, USA
Osteopontin does not mitigate cisplatin ototoxicity or nephrotoxicity in adult mice
Otolaryngology - Head and Neck Surgery
Schmitt, NC;Rubel, EW;
2013
23884286
October 1st, 2013
United States
Virginia Merrill Bloedel Hearing Research Center, Seattle, Washington, USA
Relationship between circadian period and body size in the tau-mutant golden hamster
Canadian Journal of Physiology and Pharmacology
Refinetti, R;
2014
24383870
January 1st, 2014
United States
Circadian Rhythm Laboratory, University of South Carolina, 807 Hampton Street, Walterboro, SC 29488, USA
A comparative assessment of the cytotoxicity and nitric oxide reducing ability of resveratrol, pterostilbene and piceatannol in transformed and normal mouse macrophages
Drug and Chemical Toxicology
Adiabouah Achy-Brou, CA;Billack, B;
2016
27079867
April 14th, 2016
United States
a Department of Pharmaceutical Sciences , College of Pharmacy and Health Sciences, St. John's University , Jamaica , NY , USA
Cannabinoid receptor-specific mechanisms to alleviate pain in sickle cell anemia via inhibition of mast cell activation and neurogenic inflammation
Haematologica
Vincent, L;Vang, D;Nguyen, J;Benson, B;Lei, J;Gupta, K;
2016
26703965
May 1st, 2016
United States
Vascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, MN, USA
Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease - Science Signaling
Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease
Science Signaling
Pryor, WM;Biagioli, M;Shahani, N;Swarnkar, S;Huang, WC;Page, DT;MacDonald, ME;Subramaniam, S;
2014
25351248
October 28th, 2014
United States
Department of Neuroscience, The Scripps Research Institute Florida, Jupiter, FL 33458, USA
SLC26A4 targeted to the endolymphatic sac rescues hearing and balance in Slc26a4 mutant mice
PLOS Genetics
Li, X;Sanneman, JD;Harbidge, DG;Zhou, F;Ito, T;Nelson, R;Picard, N;Chambrey, R;Eladari, D;Miesner, T;Griffith, AJ;Marcus, DC;Wangemann, P;
2013
23874234
July 22nd, 2013
United States
Anatomy & Physiology Department, Kansas State University, Manhattan, Kansas, USA
Interaction between Foxc1 and Fgf8 during mammalian jaw patterning and in the pathogenesis of syngnathia
PLOS Genetics
Inman, KE;Purcell, P;Kume, T;Trainor, PA;
2013
24385915
January 3rd, 2013
United States
Stowers Institute for Medical Research, Kansas City, Missouri, United States of America
Transient Loss of Protection Afforded by a Live Attenuated Non-typhoidal Salmonella Vaccine in Mice Co-infected with Malaria
PLOS Neglected Tropical Diseases
Mooney, JP;Lee, SJ;Lokken, KL;Nanton, MR;Nuccio, SP;McSorley, SJ;Tsolis, RM;
2015
26366739
September 15th, 2015
United States
Department of Microbiology & Immunology, School of Medicine, University of California Davis, Davis, California, United States of America
Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner
Arthritis Research and Therapy
Cuda, CM;Misharin, AV;Khare, S;Saber, R;Tsai, F;Archer, AM;Homan, PJ;Haines, GK;Hutcheson, J;Dorfleutner, A;Budinger, GR;Stehlik, C;Perlman, H;
2015
26471282
October 16th, 2015
United States
Division of Rheumatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, 240 East Huron Street, Room M300, Chicago, IL, 60611, USA
Short telomeres initiate telomere recombination in primary and tumor cells
PLOS Genetics
Morrish, TA;Greider, CW;
2009
19180191
January 1st, 2009
United States
Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America
Small-molecule nociceptin receptor agonist ameliorates mast cell activation and pain in sickle mice
Haematologica
Vang, D;Paul, JA;Nguyen, J;Tran, H;Vincent, L;Yasuda, D;Zaveri, NT;Gupta, K;
2015
26294734
December 1st, 2015
United States
Astraea Therapeutics, Mountain View, CA, USA nurulain@astraeatherapeutics.com
Ventral prostate fibrosis in the Akita mouse is associated with macrophage and fibrocyte infiltration
Journal of Diabetes Research
Lee, S;Yang, G;Mulligan, W;Gipp, J;Bushman, W;
2014
25019092
July 14th, 2014
United States
Department of Urology, University of Wisconsin School of Medicine and Public Health, Madison, WI 53717, USA ; Carbone Cancer Center, University of Wisconsin School of Medicine and Public Health, Madison, WI 53717, USA
Salmonella enterica Typhimurium as a tumor-targeting immunotherapy vector
Thesis
Drees, J;
2015
How serotonin system alterations influence emotion-and cognition-related behaviors
Thesis
Gilman, TL;
2013
Neuron to microglia communication; a study of CX3CL1 signaling implications in cognitive function, inflammation, and neurodegeneration
Thesis
Morganti, JM;
2012
Investigation of the functional and structural role of podosomes in megakaryocytes
Thesis
Schachtner, H;
2013
Role of -Glucuronidase in the Chemopreventive Efficacy of Oral Curcumin: A Prodrug Hypothesis
Thesis
Liu, G;
2015
The Role of the Dopamine D1 Receptor in Cognition
Thesis
Arola, A;
2013
Affiliation Unavailable
Role of Astrocytes in Ischemic Preconditioning-Induced Neuroprotection
Thesis
Narayanan, S;
2015
Functional characterisation of driver events in ovarian clear cell carcinoma
Thesis
Gounaris, I;
2014
Defining the role of Notch Signalling in Intrahepatic Cholangiocarcinoma
Thesis
Guest, RV;
2015
Neuronal cicuits and reinforcement mechanisms underlying feeding behaviour
Thesis
Huang Cao, ZF;
2015
Regulation of striatal medium spiny neuron GABAA receptor mediated tonic current
Thesis
Janssen Schroeder, MJ;
2010
United States
COMBINATION IMMUNOTHERAPY TARGETING IMMUNOSUPPRESSIVE SIGNALS IN THE TUMOR MICROENVIRONMENT PREVENTS CANCER PROGRESSION
Thesis
Keenan, BP;
2015
Serotonergic Modulation of Glutamate Transmission: Bridging Two Theories of Depression
Thesis
Kallarackal, AJ;
2011
United States
THE ROLE OF PPAR- IN TROPHOBLAST LAYER DYNAMICS
Thesis
Levytska, K;
2013
Canada
Laboratory Medicine and Pathobiology,University of Toronto
Defining the functional role of laminin isoforms in the regulation of the adult hepatic progenitor cell
Thesis
Williams, MJ;
2015
More than a License to Kill: Immune Regulation of Crohn's Disease by Natural Killer Cell and Its Clinical Implication
Thesis
Lin, L;
2013
United States
University of California LA
Assessment of hepatic micronutrient disruption and the hepatotoxicity of 3, 3', 4, 4', 5-pentachlorobiphenyl (PCB126)
Thesis
Klaren, WD;
2016
Neuropilin-2 in pancreatic cancer and Semaphorin-3F as a treatment
Thesis
Li, X;
2016
Cannabinoid CB1R Receptor Mediates Metabolic Syndrome in Models of Circadian and Glucocorticoid Dysregulation
Thesis
Bowles, N;
2013
The role of Netrin-1 in semicircular canal morphogenesis
Thesis
Nishitani, A;
2014
The Role of Serotonin in the Development of Psychiatric Disorders: Studies on Drug Dependence and Anxiety-like Behaviour Following the Genetic Reduction of the
Thesis
Oakly, A;
2015
Victoria University of Wellington
Examining and improving the chemopreventive efficacy of curcumin
Thesis
Grill, AE;
2012
RON Over-expression Induces Acinar-Ductal Metaplasia and Accelerates Tumorigenesis in a Kras Mutant Mouse Model of Pancreatic Cancer
Thesis
Harper, MM;
2013
United States
UC San Diego
Study of functions of shelterins and telomerase in aging and nuclear reprograming
Thesis
Garrobo Calleja, I;
2014
Universidad AutÌ_noma de Madrid, Facultad de Ciencias, Departamento de BiologÌ_a Molecular
The role of FGFR3 mutation in tumour initiation, progression and invasion of urothelial cell carcinoma in mice
Thesis
Foth, M;
2014
Requirement for fibroblast growth factor receptor 1 in hematopoietic stem cells under stress but not during homeostasis
Thesis
Ross, JT;
2010
The Mechanism of Neuroprotection Mediated By Nicotinamide Mononucleotide Adenylyl Transferase (NMNAT)
Thesis
Ali, YO;
2011
Investigating the role of caspase cleavage of ROCK1 in tissue homeostasis and tumour development
Thesis
Julian, L;
2015
The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming
Stem Cell Reports
Unternaehrer, JJ;Zhao, R;Kim, K;Cesana, M;Powers, JT;Ratanasirintrawoot, S;Onder, T;Shibue, T;Weinberg, RA;Daley, GQ;
2014
25316190
November 11th, 2014
United States
Division of Pediatric Hematology/Oncology, Stem Cell Transplantation Program, Manton Center for Orphan Disease Research, Howard Hughes Medical Institute, Children's Hospital Boston and Dana Farber Cancer Institute, Harvard University, Cambridge, MA 02138, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Harvard University, Cambridge, MA 02138, USA; Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA
Investigating downstream effectors of KRas signalling in vivo: Dusp6 and Fra1
Thesis
Moreaux, G;
2012
In vivo characterization of pituitary adenylate cyclase-activating polypeptide in mouse olfactory epithelium
Thesis
Stamm, ML;
2011
Kiss 1 neurons and metabolic sensing
Thesis
Qiu, X;
2013
Sex differences in the cardiac beta-adrenergic receptor contractile response
Thesis
Mcintosh, V;
2012
Nutraceutical Antioxidants and Their Therapeutic Potential in Neurodegeneration
Thesis
Ross, EK;
2012
AN INVESTIGATION INTO THE ROLE OF IRON, COPPER, AND GENDER IN A TRANSGENIC MOUSE MODEL OF ALZHEIMER'S DISEASE.
Thesis
Groeber, CM;
2013
Host cell factors involved in retrovirus replication and disease pathogenesis
Thesis
Seidel, SB;
2012
United States
University of California San Diego
The mechanisms of reversal of refractory dysplasia in the salivary gland: Testing the role of p53, RXR and PPARgamma agonists, and PD0332991
Thesis
Cabrera, MC;
2012
United States
Modulation of oncogenic transformation by Raf proteins
Thesis
Karreth, F;
2009
Universitat WIEN
The Effects of Specialized Proresolving Lipid Mediators on B Lymphocyte Function: Implications for B Cell Differentiation and Antibody Production
Thesis
Ramon, S;
2013
United States
University of RochesterRochester, New York
Mechanisms of epithelial cell cancer generation: genetic risk factors on cancer progression investigated using in vivo models and at a single cell level
Thesis
Nakles, RE;
2012
United States
p53 loss and Kras mutation in an invasive murine model of colorectal cancer
Thesis
Cuesta Garcia, N;
2013
Mechanisms that control the growth of cells in the presence of replication stress
Thesis
Monasor Pascual, A;
2013
Spain
UNIVERSIDAD DE ALCALÃŒÂ, Facultad de Medicina y Ciencias de la Salud, Departamento de BiologÃŒ_a de Sistemas
Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice
Oncogenesis
Xiong, X;Chorzalska, A;Dubielecka, PM;White, JR;Vedvyas, Y;Hedvat, CV;Haimovitz-Friedman, A;Koutcher, JA;Reimand, J;Bader, GD;Sawicki, JA;Kotula, L;
2012
23552839
September 3rd, 2012
United States
Laboratory of Cell Signaling, New York Blood Center, New York, NY, USA
Regulation of DMD pathology by an ankyrin-encoded miRNA
Skeletal Muscle
Alexander, MS;Casar, JC;Motohashi, N;Myers, JA;Eisenberg, I;Gonzalez, RT;Estrella, EA;Kang, PB;Kawahara, G;Kunkel, LM;
2011
21824387
August 8th, 2011
United States
Program in Genomics and Division of Genetics, Children's Hospital Boston, 3 Blackfan Circle, CLS15024, Boston, MA 02115, USA
CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State
Stem Cell Reports
Zheng, X;Yang, P;Lackford, B;Bennett, BD;Wang, L;Li, H;Wang, Y;Miao, Y;Foley, JF;Fargo, DC;Jin, Y;Williams, CJ;Jothi, R;Hu, G;
2016
27746116
November 8th, 2016
United States
Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA
Pericyte structure and distribution in the cerebral cortex revealed by high-resolution imaging of transgenic mice
Neurophotonics
Hartmann, DA;Underly, RG;Grant, RI;Watson, AN;Lindner, V;Shih, AY;
2015
26158016
October 1st, 2015
United States
Medical University of South Carolina , Department of Neurosciences, 173 Ashley Avenue CRI 406, Charleston, South Carolina 29425, United States ; Medical University of South Carolina , Center for Biomedical Imaging, 68 President Street, Charleston, South Carolina 29425, United States
Transcription factor activator protein 2C and downstream redox biology effectors in development and carcinogenesis
Thesis
Cyr, AR;
2014
Crosstalk between the canonical NF-B and Notch signaling pathways inhibits Ppar expression and promotes pancreatic cancer progression in mice
The Journal of Clinical Investigation‰
Maniati, E;Bossard, M;Cook, N;Candido, JB;Emami-Shahri, N;Nedospasov, SA;Balkwill, FR;Tuveson, DA;Hagemann, T;
2011
December 6th, 2011
United Kindom
1Centre for Cancer and Inflammation, Barts Cancer Institute, Queen Mary University of London
Altered AIB1 or AIB13 expression impacts ER effects on mammary gland stromal and epithelial content
Molecular Endocrinology
Nakles, RE;Shiffert, MT;DÌ_az-Cruz, ES;Cabrera, MC;Alotaiby, M;Miermont, AM;Riegel, AT;Furth, PA;
2011
February 3rd, 2011
United States
Georgetown University, Room E520A, Research Building, 3970 Reservoir Road Northwest, Washington, D.C. 20057
Diphtheria toxin-mediated ablation of lymphatic endothelial cells results in progressive lymphedema
JCI Insight
Gardenier, JC;Hespe, GE;Kataru, RP;Savetsky, IL;Torrisi, JS;Nores, GD;Dayan, JJ;Chang, D;Zampell, J;MartÌ_nez-Corral, I;Ortega, S;Mehrara, BJ;
2016
27699240
September 22nd, 2016
United States
Section of Plastic and Reconstructive Surgery, The University of Chicago Medicine and Biological Sciences, Chicago, Illinois, USA
Role of the Regulator of G protein Signaling 4 in renal ischemic reperfusion injury and repair
Thesis
Pang, PD;
2013
Mapping Functional Brain Activation Using [14 C]-Iodoantipyrine in Male Serotonin Transporter Knockout Mice
PLOS ONE
Pang, RD;Wang, Z;Klosinski, LP;Guo, Y;Herman, DH;Celikel, T;Dong, HW;Holschneider, DP;
2011
August 23rd, 2011
United States
Graduate Program in Neuroscience, University of Southern California
Reduction in hSOD1 copy number significantly impacts ALS phenotype presentation in G37R (line 29) mice: implications for the assessment of putative therapeutic agents
Journal of Negative Results in Biomedicine
Zwiegers, P;Lee, G;Shaw, CA;
2014
25103619
August 8th, 2014
United States
Program in Experimental Medicine, University of British Columbia, Vancouver, Canada
Biosynthesis of the major brain gangliosides GD1a and GT1b
Glycobiology
Sturgill, ER;Aoki, K;Lopez, PH;Colacurcio, D;Vajn, K;Lorenzini, I;ۈ , SM;Yang, WH;Heffer, M;Tiemeyer, M;Marth, JD;Schnaar, RL;
2012
June 26th, 2012
United States
Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, 725 N. Wolfe Street, Baltimore, MD 21205, USA
The Role of Dietary Copper and Zinc on Inflammation and Oxidative Stress in Alzheimer's Disease
Thesis
Boggs, K;
2015
An Investigation into the Role of Copper Deficiency and Zinc in a Mouse Model of Early Onset Alzheimer's Disease.
Thesis
Howell, SN;
2014
SELECTIVE MOLECULAR MODIFICATION TO CALCIUM CONDUCTANCE DOMAINS OF NMDA RECEPTOR GLUN2 SUBUNITS REGULATES MATURATION OF
Thesis
Sanders, EM;
2014
United States
George Mason University
The role of neuropilin 2 in physiological and pathological angiogenesis
Thesis
Levonyak, NS;
2013
Genome wide gene expression analysis of two ENU mouse models of major mental illness
Thesis
Brown, SM;
2011
Identification of a maleimide-based glycogen synthase kinase-3 (GSK-3) inhibitor, BIP-135, that prolongs the median survival time of 7 SMA KO mouse model of
ACS Chemical Neuroscience
Chen, PC;Gaisina, IN;El-Khodor, BF;Ramboz, S;Makhortova, NR;Rubin, LL;Kozikowski, AP;
2011
October 18th, 2011
United States
Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, Illinois 60612, United States
Receptor-Dependent Phagocytosis of Clostridium sordellii by Human Decidual Macrophages
Thesis
Thelen, TD;
2010
Contribution of Organic Cation Transporter 2 (OCT2) to CisplatinInduced Nephrotoxicity
Clinical Pharmacology & Therapeutics
Filipski, KK;Mathijssen, RH;Mikkelsen, TS;Schinkel, AH;Sparreboom, A;
2009
July 22nd, 2009
United States
Department of Pharmaceutical Sciences, St Jude Children's Research Hospital,262 Danny Thomas Place Memphis, TN 38105-3678 USA
Synaptic molecular imaging in spared and deprived columns of mouse barrel cortex with array tomography
Scientific Data
Weiler, NC;Collman, F;Vogelstein, JT;Burns, R;Smith, SJ;
2014
25977797
May 15th, 2014
United States
Graduate Program in Neurosciences, Stanford University School of Medicine , Stanford, California 94305, USA ; Department of Molecular and Cellular Physiology, Stanford University School of Medicine , Stanford, California 94305, USA
Genetic Pharmacotherapy as an Early CNS Drug Development Strategy: Testing Glutaminase Inhibition for Schizophrenia Treatment in Adult Mice
Frontiers in Systems Neuroscience
Mingote, S;Masson, J;Gellman, C;Thomsen, GM;Lin, CS;Merker, RJ;Gaisler-Salomon, I;Wang, Y;Ernst, R;Hen, R;Rayport, S;
2015
26778975
January 18th, 2015
United States
Department of Psychiatry, Columbia UniversityNew York, NY, USA; Department of Molecular Therapeutics, New York State Psychiatric InstituteNew York, NY, USA
Novel tubulin and tau neuroprotective fragments sharing structural similarities with the drug candidate NAP (Davuentide)
Journal of Alzheimers Disease
Gozes, I;Iram, T;Maryanovsky, E;Arviv, C;Rozenberg, L;Schirer, Y;Giladi, E;Furman-Assaf, S;
2014
24503616
May 28th, 2014
Israel
The Adams Super Center for Brain Studies and Sagol School of Neuroscience; The Lily and Avraham Gildor Chair for the Investigation of Growth Factors, The Dr. Diana and Zelman Elton (Elbaum) Laboratory for Neuroendocrinology, Department of Human Molecular Genetics and Biochemistry, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Deregulated estrogen receptor alpha-initiated preneoplasia and its progression: Role of STAT5A and cyclin D1
Thesis
Miermont, AM;
2009
United States
Human ApoE ëµ4 alters circadian rhythm activity, IL-1ë_, and GFAP in CRND8 mice
J. Alzheimers Dis.
Graybeal, JJ;Bozzelli, PL;Graybeal, LL;Groeber, CM;McKnight, PE;Cox, DN;Flinn, JM;
2015
25159669
December 5th, 2015
United States
Department of Psychology, George Mason University, Fairfax, VA, USA
The role of neuropilin 2 in physiological and pathological angiogenesis and lymphangiogenesis
Thesis
Mucka, P;
2014
Further validation to support clinical translation of [(18)F]FTC-146 for imaging sigma-1 receptors
EJNMMI Res
Shen, B;James, ML;Andrews, L;Lau, C;Chen, S;Palner, M;Miao, Z;Arksey, NC;Shuhendler, AJ;Scatliffe, S;Kaneshige, K;Parsons, SM;McCurdy, CR;Salehi, A;Gambhir, SS;Chin, FT;
2015
26384292
December 1st, 2015
United States
Molecular Imaging Program at Stanford (MIPS) Department of Radiology Stanford University, Stanford, CA, 94305, USA
Does Prenatal Valproate Interact with a Genetic Reduction in the Serotonin Transporter? A Rat Study on Anxiety and Cognition
Frontiers in Neuroscience
Ellenbroek, BA;August, C;Youn, J;
2016
27708559
October 6th, 2016
New Zealand
School of Psychology, Victoria University of Wellington Wellington, New Zealand
In vivo axonal transport deficits in a mouse model of fronto-temporal dementia - Neuroimage Clinical
In vivo axonal transport deficits in a mouse model of fronto-temporal dementia
Neuroimage Clinical
Majid, T;Ali, YO;Venkitaramani, DV;Jang, MK;Lu, HC;Pautler, RG;
2014
24936422
June 17th, 2014
United States
Interdepartmental Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, TX, USA ; Department of Molecular Physiology and Biophysics, Baylor College of Medicine, USA
Impact of the loss of caveolin-1 on lung mass and cholesterol metabolism in mice with and without the lysosomal cholesterol transporter, Niemann-Pick type C1
Biochimica et Biophysica Acta Journal (BBA)
Mundy, DI;Lopez, AM;Posey, KS;Chuang, JC;Ramirez, CM;Scherer, PE;Turley, SD;
2014
24747682
July 1st, 2014
United States
Department of Internal Medicine, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, USA
Quantitative Analysis of Supporting Cell Subtype Labeling Among CreER Lines in the Neonatal Mouse Cochlea
Journal of the Association for Research in Otolaryngology (JARO)
McGovern, MM;Brancheck, J;Grant, AC;Graves, KA;Cox, BC;
2016
27873085
November 21st, 2016
United States
Department of Pharmacology, Southern Illinois University School of Medicine, Springfield, IL, 62711, USA
A Cystine-Rich Whey Supplement (Immunocal(å¨)) Delays Disease Onset and Prevents Spinal Cord Glutathione Depletion in the hSOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis
Antioxidants (Basel)
Ross, EK;Winter, AN;Wilkins, HM;Sumner, WA;Duval, N;Patterson, D;Linseman, DA;
2014
26785244
December 12th, 2014
United States
Department of Biological Sciences and Eleanor Roosevelt Institute, University of Denver, 2199 S. University Blvd., Denver, CO 80208, USA
Deletion of the type-1 interferon receptor in APPSWE/PS1ëÓE9 mice preserves cognitive function and alters glial phenotype
Acta Neuropathologica Communications
Minter, MR;Moore, Z;Zhang, M;Brody, KM;Jones, NC;Shultz, SR;Taylor, JM;Crack, PJ;
2016
27400725
July 11th, 2016
Australia
Department of Pharmacology and Therapeutics, University of Melbourne, 8th floor, Medical building, Grattan St, Parkville, Melbourne, 3010, Victoria, Australia
Brain-specific interleukin-1 receptor accessory protein in sleep regulation
Journal of Applied Physiology
Taishi, P;Davis, CJ;Bayomy, O;Zielinski, MR;Liao, F;Clinton, JM;Smith, DE;Krueger, JM;
2012
22174404
March 1st, 2012
United States
Sleep and Performance Research Center, WWAMI Medical Education Program, Washington State University, Spokane, WA 99210-1495, USA
Modulating dopamine release by optogenetics in transgenic mice reveals terminal dopaminergic dynamics
Neurophotonics
Lu, Y;Driscoll, N;Ozden, I;Yu, Z;Nurmikko, AV;
2015
26171413
July 1st, 2015
United States
Brown University , School of Engineering, Providence, Rhode Island 02912, United States ; Brown University , Institute of Brain Science, Providence, Rhode Island 02912, United States
Early exposure to environmental toxin contributes to neuronal vulnerability and axonal pathology in a model of familial ALS
Neuroscience & Medicine
Lee, G;Shaw, CA;
2012
November 4th, 2012
United States
Department of Experimental Medicine, University of British Columbia
B cell and/or autoantibody deficiency do not prevent neuropsychiatric disease in murine systemic lupus erythematosus
Journal of Neuroinflammation
Wen, J;Doerner, J;Chalmers, S;Stock, A;Wang, H;Gullinello, M;Shlomchik, MJ;Putterman, C;
2016
April 7th, 2016
United States
Department of Microbiology and Immunology, Albert Einstein College of Medicine
Community pharmacists' experience with pharmacogenetic testing
Journal of American Pharmicists Association (2003)
Moaddeb, J;Mills, R;Haga, SB;
2015
26409205
September 27th, 2015
United States
Center for Applied Genomics and Precision Medicine, Department of Medicine, Duke University School of Medicine, Durham, NC
Metallothionein's role in PCB126 induced hepatotoxicity and hepatic micronutrient disruption
Toxicology Reports
Klaren, WD;Flor, S;Gibson-Corley, KN;Ludewig, G;Robertson, LW;
2016
26770886
January 15th, 2016
United States
Interdisciplinary Graduate Program in Human Toxicology, University of Iowa, Iowa City, Iowa; Department of Occupational and Environmental Health, College of Public Health, University of Iowa, Iowa City, Iowa
Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging
F1000Research
Arum, O;Saleh, J;Boparai, R;Turner, J;Kopchick, J;Khardori, R;Bartke, A;
2014
25789159
March 19th, 2014
United States
Department of Internal Medicine, Southern Illinois University-School of Medicine, Springfield, IL, 62794, USA
Ganglioside accumulation in glia during neurodegeneration and glial activation in the developing brain: Comparison between wild-type and GM2/GD2 synthase knock
Journal of Lipid Research
Saito, M;Wu, G;Hui, M;Masiello, K;Dobrenis, K;Ledeen, RW;Saito, M;
2015
June 10th, 2015
United States
Nathan Kline Institute for Psychiatric Research,140 Old Orangeburg Rd, Orangeburg, NY 10962
Identification of the pre-B̦tzinger complex inspiratory center in calibrated sandwich slices from newborn mice with fluorescent Dbx1 interneurons
Physiology Reports
Ruangkittisakul, A;Kottick, A;Picardo, MC;Ballanyi, K;Del Negro, CA;
2014
25138790
August 1st, 2014
Canada
Department of Physiology, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Alberta, Canada
Are Researchers Making the Most of Germ-Free Models?
Taconic
Vitale, J;
2014
September 13th, 2014
United States
Taconic Insights, One Hudson City Centre,Hudson, NY 12534
Generation of Kcnma1fl-tdTomato, a conditional deletion of the BK channel ë± subunit in mouse
Physiology Reports
Zemen, BG;Lai, MH;Whitt, JP;Khan, Z;Zhao, G;Meredith, AL;
2015
26537348
November 1st, 2015
United States
Department of Physiology, University of Maryland School of Medicine, Baltimore, Maryland
Association of Over-Expressed Estrogen Receptor Alpha with Development of Tamoxifen Resistant Hyperplasia and Adenocarcinomas in Genetically Engineered Mice
Anatomy & Physiology : Current Research
Miermont, AM;Cabrera, MC;Frech, SM;Nakles, RE;Diaz-Cruz, ES;Shiffert, MT;Furth, PA;
2012
24575359
June 25th, 2012
United States
Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20007, USA ; Department of Medicine, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, 20007, USA ; Department of Nanobiomedical Science and WCU Research Center of Nanobiomedical Science, Dankook University, Chungnam 330-714, Korea
Administration of CoQ 10 analogue ameliorates dysfunction of the mitochondrial respiratory chain in a mouse model of Angelman syndrome
Neurobiology of Disease
Llewellyn, KJ;Nalbandian, A;Gomez, A;Wei, D;Walker, N;Kimonis, VE;
2015
February 12th, 2015
United States
Department of Pediatrics, Division of Genetics and Genomics, University of California-Irvine
Pendrin gene ablation alters ENaC subcellular distribution and open probability
American Journal of Physiology Renal Physiology
Pech, V;Wall, SM;Nanami, M;Bao, HF;Kim, YH;Lazo-Fernandez, Y;Yue, Q;Pham, TD;Eaton, DC;Verlander, JW;
2015
25972513
July 15th, 2015
United States
Department of Medicine, Emory University School of Medicine, Atlanta, Georgia; Department of Physiology, Emory University School of Medicine, Atlanta, Georgia; and
The role of the 7 subunit of the nicotinic acetylcholine receptor in the acute toxicosis of methyllycaconitine in mice
Journal of Applied Toxicology
Welch, KD;Green, BT;Panter, KE;Pfister, JA;Gardner, DR;
2013
January 8th, 2013
United States
USDA-ARS Poisonous Plant Research Laboratory
Type II Cochlear Ganglion Neurons Do Not Drive the Olivocochlear Reflex: Re-Examination of the Cochlear Phenotype in Peripherin Knock-Out Mice
eNeuro
Maison, S;Liberman, LD;Liberman, MC;
2016
27570826
August 29th, 2016
United States
Department of Otology and Laryngology, Harvard Medical School, Boston, Massachusetts 02115; Eaton-Peabody Laboratories, Massachusetts Eye & Ear Infirmary, Boston, Massachusetts 02114-3096
The CDK4/6 inhibitor PD0332991 reverses epithelial dysplasia associated with abnormal activation of the cyclin-CDK-Rb pathway
Cancer Prev Res (Phila)
Cabrera, MC;DÌ_az-Cruz, ES;Kallakury, BV;Pishvaian, MJ;Grubbs, CJ;Muccio, DD;Furth, PA;
2012
22508966
June 1st, 2012
United States
Department of Oncology, Georgetown University, Washington, DC 20057, USA
Altered Responses to Cold Environment in Urocortin 1 and Corticotropin-Releasing Factor Deficient Mice
Physiology Journal
Chaker, B;Samra, TA;Datta, NS;Abou-Samra, AB;
2013
April 23rd, 2013
United States
Endocrine Division, Department of Medicine,Wayne State University School of Medicine, Detroit, MI 48201, USA
Obesity and diabetes cause cognitive dysfunction in the absence of accelerated ë_-amyloid deposition in a novel murine model of mixed or vascular dementia
Acta Neuropathologica Communications
Niedowicz, DM;Reeves, VL;Platt, TL;Kohler, K;Beckett, TL;Powell, DK;Lee, TL;Sexton, TR;Song, ES;Brewer, LD;Latimer, CS;Kraner, SD;Larson, KL;Ozcan, S;Norris, CM;Hersh, LB;Porter, NM;Wilcock, DM;Murphy, MP;
2014
24916066
June 10th, 2014
United States
Sanders Brown Center on Aging, University of Kentucky, 800 S, Limestone, Sanders Brown 211, Lexington, KY 40536-0230, USA
Short Course
Pathobiology & Phenotyping
Brayton, C;Forbes, N;Watson, J;
2015
United States
Johns Hopkins University School of Medicine
2006 ALA Survey on Industrial Laboratory Automation
Journal of the Association for Laboratory Automation
Hamilton, SD;
2007
August 1st, 2017
United States
Sanitas Consulting, Boulder, CO
Effects of cell-type specific hIL-10 expression on disease susceptibility (51.5)
The Journal of Immunology
Ranatunga, D;Hedrich, C;Wang, F;McVicar, D;Norwak, N;Joshi, T;Feigenbaum, L;Grant, L;Stager, S;Bream, J;
2010
April 1st, 2010
United States
W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins University, Bloomberg School of Public Health
ATP and the purine type 2 X7 receptor affect sleep
Journal of Applied Physiology
Krueger, JM;Taishi, P;De, A;Davis, CJ;Winters, BD;Clinton, J;Szentirmai, E;Zielinski, MR;
2010
20829501
November 1st, 2010
United States
Sleep and Performance Research Center, Programs in Neuroscience, Dept. of Veterinary and Comparative Anatomy, Pharmacology, and Physiology, College of Veterinary Medicine, Washington State University, Pullman, WA 99164-6520, USA
Ascorbate depletion increases growth and metastasis of melanoma cells in vitamin C deficient mice
Experimental Oncology
Cha, J;Roomi, MW;Ivanov, V;Kalinovsky, T;Niedzwiecki, A;Rath, M;
2011
22217712
December 1st, 2011
United States
Dr. Rath Research Institute, Cancer Division, Santa Clara, CA-95050, USA
Nitric oxide reduces Cl‰ÂÈ absorption in the mouse cortical collecting duct through an ENaC-dependent mechanism
American Journal of Physiology
Pech, V;Thumova, M;Dikalov, SI;Hummler, E;Rossier, BC;Harrison, DG;Wall, SM;
2013
23515718
June 1st, 2013
United States
Department of Medicine, Renal Division, Emory University School of Medicine, Atlanta, GA, USA
Program and Abstracts of the 10th Transgenic Technology Meeting (TT2011)
Transgenic Research
Sobieszczuk, P;Pease, S;Fielder, T;Cameron, A;
2011
September 16th, 2011
United States
TradeWinds Island Grand Resort, St Pete Beach, Florida, USA
Loss of Jagged1 in renin progenitors leads to focal kidney fibrosis
Physiology Reports
Belyea, BC;Xu, F;Sequeira-Lopez, ML;Ariel Gomez, R;
2015
26537340
November 1st, 2015
United States
Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, Virginia
An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks
Current Biology
Bedont, JL;LeGates, TA;Buhr, E;Bathini, A;Ling, JP;Bell, B;Wu, MN;Wong, PC;Van Gelder, RN;Mongrain, V;Hattar, S;Blackshaw, S;
2016
28017605
December 18th, 2016
United States
Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA
Injectable, Guest-Host Assembled Polyethylenimine Hydrogel for siRNA Delivery
Biomacromolecules
Wang, LL;Sloand, JN;Gaffey, AC;Venkataraman, CM;Wang, Z;Trubelja, A;Hammer, DA;Atluri, P;Burdick, JA;
2016
27997133
December 20th, 2016
United States
Department of Bioengineering, ‰ÛÃDivision of Cardiovascular Surgery, Department of Surgery, and å¤Department of Chemical and Biomolecular Engineering, University of Pennsylvania , Philadelphia, Pennsylvania 19104, United States
IL-15 Enables Septic Shock by Maintaining NK Cell Integrity and Function
Journal of Immunology
Guo, Y;Luan, L;Patil, NK;Wang, J;Bohannon, JK;Rabacal, W;Fensterheim, BA;Hernandez, A;Sherwood, ER;
2016
28031340
December 28th, 2016
United States
Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37212; and
Interleukin 37 expression in mice alters sleep responses to inflammatory agents and influenza virus infection
Neurobiology of Sleep and Circadian Rhythms
Davis, CJ;Zielinski, MR;Dunbrasky, D;Taishi, P;Dinarello, CA;Krueger, JM;
2016
December 2nd, 2016
United States
Elson S. Floyd College of Medicine, Department of Biomedical Sciences, Washington State University
Distinct Brca1 Mutations Differentially Reduce Hematopoietic Stem Cell Function
Cell Reports
Mgbemena, VE;Signer, RA;Wijayatunge, R;Laxson, T;Morrison, SJ;Ross, TS;
2017
28122244
January 24th, 2017
United States
Department of Internal Medicine, Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
Experimental Design and Data Analysis Issues Contribute to Inconsistent Results of C-Bouton Changes in Amyotrophic Lateral Sclerosis
eNeuro
Dukkipati, SS;Chihi, A;Wang, Y;Elbasiouny, SM;
2017
28101533
January 19th, 2017
United States
Department of Neuroscience, Cell Biology, and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, Ohio 45435; Department of Biomedical, Industrial, and Human Factors Engineering, College of Engineering and Computer Science, Wright State University, Dayton, Ohio 45435
Complement C5a receptor is the key initiator of neutrophil adhesion igniting immune complex‰ÛÒinduced arthritis
Science Immunology
Miyabe, Y;Miyabe, C;Murooka, TT;Kim, EY;Newton, GA;Kim, ND;Haribabu, B;Luscinskas, FW;Mempel, TR;Luster, AD;
2017
January 20th, 2017
United States
Center for Immunology and Inflammatory Diseases, Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital
Tumor-Infiltrating Merkel Cell Polyomavirus-Specific T Cells Are Diverse and Associated with Improved Patient Survival.
Cancer Immunology Research
Miller, NJ;Church, CD;Dong, L;Crispin, D;Fitzgibbon, MP;Lachance, K;Jing, L;Shinohara, M;Gavvovidis, I;Willimsky, G;McIntosh, M;Blankenstein, T;Koelle, DM;Nghiem, P;
2017
28093446
February 1st, 2017
United States
Dermatology/Medicine/Pathology, University of Washington, Seattle, Washington.
Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin
Current Biology
Woodham, EF;Paul, NR;Tyrrell, B;Spence, HJ;Swaminathan, K;Scribner, MR;Giampazolias, E;Hedley, A;Clark, W;Kage, F;Marston, DJ;Hahn, KM;Tait, SW;Larue, L;Brakebusch, CH;Insall, RH;Machesky, LM;
2017
28238662
February 18th, 2017
United Kingdom
CRUK Beatson Institute, University of Glasgow, Switchback Road, Bearsden, Glasgow G61 1BD, UK
CatSperë¦ regulates the structural continuity of sperm Ca(2+) signaling domains and is required for normal fertility
Elife
Chung, JJ;Miki, K;Kim, D;Shim, SH;Shi, HF;Hwang, JY;Cai, X;Iseri, Y;Zhuang, X;Clapham, DE;
2017
28226241
February 22nd, 2017
United States
Department of Cellular and Molecular Physiology, Yale School of Medicine, New Haven, United States
Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells
Elife
Sternfeld, MJ;Hinckley, CA;Moore, NJ;Pankratz, MT;Hilde, KL;Driscoll, SP;Hayashi, M;Amin, ND;Bonanomi, D;Gifford, WD;Sharma, K;Goulding, M;Pfaff, SL;
2017
28195039
February 14th, 2017
United States
Gene Expression Laboratory, Howard Hughes Medical Institute, Salk Institute for Biological Studies, La Jolla, United States
Frequent Zika Virus Sexual Transmission and Prolonged Viral RNA Shedding in an Immunodeficient Mouse Model
Cell Reports
Duggal, NK;Ritter, JM;Pestorius, SE;Zaki, SR;Davis, BS;Chang, GJ;Bowen, RA;Brault, AC;
2017
28199846
February 14th, 2017
United States
Division of Vector-Borne Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
Two modes of enteric gliotransmission differentially affect gut physiology
Glia
GrubiÂÃiۈ , V;Parpura, V;
2017
28168732
February 7th, 2017
United States
Department of Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama
Epileptiform activity and behavioral arrests in mice overexpressing the calcium channel subunit ë±2ë«-1
Neurobiology of Disease
Faria, LC;Gu, F;Parada, I;Barres, B;David Luo, Z;Prince, DA;
2017
28193459
February 10th, 2017
United States
Department of Neurology and Neurological Sciences, Stanford University, School of Medicine, Stanford, CA 94305, USA
Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation
PLOS ONE
Loomis, Z;Eigenberger, P;Redinius, K;Lisk, C;Karoor, V;Nozik-Grayck, E;Ferguson, SK;Hassell, K;Nuss, R;Stenmark, K;Buehler, P;Irwin, DC;
2017
28152051
February 2nd, 2017
United States
Cardiovascular and Pulmonary Research Laboratory, Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado, United States of America
Ablation of Cyclophilin D Results in an Activation of FAK, Akt and ERK Pathways in the Mouse Heart
Journal of Cellular Biochemistry
Klawitter, J;Seres, T;Pennington, A;Beatty, JT;Klawitter, J;Christians, U;
2017
28230282
February 23rd, 2017
United States
Department of Anesthesiology, University of Colorado Denver, Anschutz Medical Campus, Aurora, Colorado
Action Potentials and Ion Conductances in Wild-type and CALHM1-knockout Type II Taste Cells
Journal of Neurophysiology
Ma, Z;Saung, WT;Foskett, JK;
2017
28202574
February 15th, 2017
United States
University of Pennsylvania School of Medicine
A Longitudinal Investigation into the Effect of Zn and Cu on Spatial Learning/Memory and Social Preference in a Mouse Model of LOAD
Thesis
Howell, SN;
2016
United States
George Mason University
Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model
Biochimica et Biophysica Acta
Bichell, TJ;Wegrzynowicz, M;Grace Tipps, K;Bradley, EM;Uhouse, MA;Bryan, M;Horning, K;Fisher, N;Dudek, K;Halbesma, T;Umashanker, P;Stubbs, AD;Holt, HK;Kwakye, GF;Tidball, AM;Colbran, RJ;Aschner, M;Diana Neely, M;Di Pardo, A;Maglione, V;Osmand, A;Bowman, AB;
2017
28213125
February 14th, 2017
United States
Department of Pediatrics, Vanderbilt University (VU), Vanderbilt University Medical Center (VUMC), Nashville, TN, USA; Department of Neurology, Vanderbilt University (VU), Vanderbilt University Medical Center (VUMC), Nashville, TN, USA; Department of Biochemistry, Vanderbilt University (VU), Vanderbilt University Medical Center (VUMC), Nashville, TN, USA; Vanderbilt Brain Institute, VUMC
Parvalbumin Interneurons Modulate Striatal Output and Enhance Performance during Associative Learning
Neuron
Lee, K;Holley, SM;Shobe, JL;Chong, NC;Cepeda, C;Levine, MS;Masmanidis, SC;
2017
28334608
March 22nd, 2017
United States
Department of Neurobiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA; California Nanosystems Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA; Brain Research Institute, Integrative Center for Learning and Memory, University of California, Los Angeles, Los Angeles, CA 90095, USA
Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice
Elife
Bucks, SA;Cox, BC;Vlosich, BA;Manning, JP;Nguyen, TB;Stone, JS;
2017
28263708
March 6th, 2017
United States
Department of Otolaryngology-Head and Neck Surgery, Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, United States
Mebendazole and a non-steroidal anti-inflammatory combine to reduce tumor initiation in a colon cancer preclinical model
Oncotarget
Williamson, T;Bai, RY;Staedtke, V;Huso, D;Riggins, GJ;
2016
27612418
October 18th, 2016
United States
Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Mertk on tumor macrophages is a therapeutic target to prevent tumor recurrence following radiation therapy
Oncotarget
Crittenden, MR;Baird, J;Friedman, D;Savage, T;Uhde, L;Alice, A;Cottam, B;Young, K;Newell, P;Nguyen, C;Bambina, S;Kramer, G;Akporiaye, E;Malecka, A;Jackson, A;Gough, MJ;
2016
27602953
November 29th, 2016
United States
Earle A. Chiles Research Institute, Robert W. Franz Cancer Center, Providence Portland Medical Center, Portland OR, USA
Abnormal Capillary Vasodynamics Contribute to Ictal Neurodegeneration in Epilepsy
Scientific Reports
Leal-Campanario, R;Alarcon-Martinez, L;Rieiro, H;Martinez-Conde, S;Alarcon-Martinez, T;Zhao, X;LaMee, J;Popp, PJ;Calhoun, ME;Arribas, JI;Schlegel, AA;Stasi, LL;Rho, JM;Inge, L;Otero-Millan, J;Treiman, DM;Macknik, SL;
2017
28240297
February 27th, 2017
United States
Barrow Neurological Institute, 350 W Thomas Rd, Phoenix, AZ 85013, USA
Absence of a gestational diabetes phenotype in the LepRdb/+ mouse is independent of control strain, diet, misty allele, or parity
Scientific Reports
Plows, JF;Yu, X;Broadhurst, R;Vickers, MH;Tong, C;Zhang, H;Qi, H;Stanley, JL;Baker, PN;
2017
28338021
March 24th, 2017
New Zealand
Liggins Institute, University of Auckland, New Zealand
Adrenocorticotropic hormone protects learning and memory function in epileptic Kcna1-null mice
Neuroscience Letters
Scantlebury, MH;Chun, KC;Ma, SC;Rho, JM;Kim, DY;
2017
28249786
April 3rd, 2017
United States
Department of Neurology and Neurobiology, Barrow Neurological Institute, St. Joseph Hospital and Medical Center Phoenix, Arizona, USA
An anthocyanin-enriched extract from strawberries delays disease onset and extends survival in the hSOD1(G93A) mouse model of amyotrophic lateral sclerosis
Nutritional Neuroscience
Winter, AN;Ross, EK;Wilkins, HM;Stankiewicz, TR;Wallace, T;Miller, K;Linseman, DA;
2017
28276271
March 9th, 2017
United States
a Department of Biological Sciences , Eleanor Roosevelt Institute, University of Denver , 2199 S. University Blvd., Denver , CO 80208 , USA
Responsiveness of Brca1 and Trp53 Deficiency-Induced Mammary Preneoplasia to Selective Estrogen Modulators versus an Aromatase Inhibitor in Mus musculus
Cancer Prevention Research (Phila)
Alothman, SJ;Wang, W;Goerlitz, DS;Islam, M;Zhong, X;Kishore, A;Azhar, RI;Kallakury, BV;Furth, PA;
2017
28283467
March 10th, 2017
United States
Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC
Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice
Nature
Becker, LA;Huang, B;Bieri, G;Ma, R;Knowles, DA;Jafar-Nejad, P;Messing, J;Kim, HJ;Soriano, A;Auburger, G;Pulst, SM;Taylor, JP;Rigo, F;Gitler, AD;
2017
28405022
April 20th, 2017
United States
Department of Genetics, Stanford University School of Medicine, Stanford, California 94305, USA
Modulating the therapeutic response of tumours to dietary serine and glycine starvation
Nature
Maddocks, ODK;Athineos, D;Cheung, EC;Lee, P;Zhang, T;van den Broek, NJF;Mackay, GM;Labuschagne, CF;Gay, D;Kruiswijk, F;Blagih, J;Vincent, DF;Campbell, KJ;Ceteci, F;Sansom, OJ;Blyth, K;Vousden, KH;
2017
28425994
April 19th, 2017
United Kingdom
Cancer Research UK Beatson Institute, Switchback Road, Glasgow G61 1BD, UK
Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion
Nature Communications
Gundry, C;Marco, S;Rainero, E;Miller, B;Dornier, E;Mitchell, L;Caswell, PT;Campbell, AD;Hogeweg, A;Sansom, OJ;Morton, JP;Norman, JC;
2017
28294115
March 15th, 2017
United Kingdom
CRUK Beatson Institute for Cancer Research, Garscube Estate, Glasgow G61 1BD, UK
Embryonic transcription factor expression in mice predicts medial amygdala neuronal identity and sex-specific responses to innate behavioral cues
Elife
Lischinsky, JE;Sokolowski, K;Li, P;Esumi, S;Kamal, Y;Goodrich, M;Oboti, L;Hammond, TR;Krishnamoorthy, M;Feldman, D;Huntsman, M;Liu, J;Corbin, JG;
2017
28244870
March 13th, 2017
United States
Center for Neuroscience Research, Children's National Medical Center, Washington, DC, United States
Astrocytes modulate thalamic sensory processing via mGlu2 receptor activation
Neuropharmacology
Copeland, CS;Wall, TM;Sims, RE;Neale, SA;Nisenbaum, E;Parri, HR;Salt, TE;
2017
28416443
April 14th, 2017
United Kingdom
Institute of Ophthalmology, University College London, 11-43 Bath Street, London, EC1V 9EL, UK; St George's, University of London, Cranmer Terrace, London, SW17 0RE, UK
Investigating the Role of Serotonin in Methamphetamine Psychosis: Unaltered Behavioral Effects of Chronic Methamphetamine in 5-HT1A Knockout Mice
Frontiers in Psychiatry
Jaehne, EJ;Ameti, D;Paiva, T;van den Buuse, M;
2017
28473777
May 5th, 2017
Australia
Department Psychology and Counselling, School of Psychology and Public Health, La Trobe University, Melbourne, VIC, Australia
Embryonic Transcription Factor Expression Predicts Neuronal Identity and Innate Behavioral Activation Patterns in the Limbic System
Thesis
Lischinsky, JE;
2017
United States
George Washington University
Protease induced plasticity: Matrix metalloproteinase-1 activation of protease activated receptor 1 induces neuronal structural plasticity
Thesis
Allen, M;
2017
United States
Arts and Sciences of Georgetown University
PPARë_-pERK interaction restores memory consolidation in an Alzheimer's disease model
Thesis
Jahrling, J;
2017
United States
University of Texas Medical Branch
Chemopreventive efficacy of curcumin-loaded PLGA microparticles in a transgenic mouse model of HER-2-positive breast cancer
Drug Delivery and Translational Research
Grill, AE;Shahani, K;Koniar, B;Panyam, J;
2017
28417445
April 17th, 2017
United States
Department of Pharmaceutics, College of Pharmacy, University of Minnesota, 9-177 Weaver Densford Hall, 308 Harvard Street, S.E, Minneapolis, MN, 55455, USA
Treadmill exercise delays the onset of non-motor behaviors and striatal pathology in the CAG140 knock-in mouse model of Huntington's disease.
Neurobiology of Disease
Stefanko, DP;Shah, VD;Yamasaki, WK;Petzinger, GM;Jakowec, MW;
2017
28502806
May 11th, 2017
United States
Department of Neurology, University of Southern California, Los Angeles, CA, 91007, United States; Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, CA, 91007, United States
The role of the brown adipose tissue in ë_3-adrenergic receptor activation-induced sleep, metabolic and feeding responses
Scientific Reports
Szentirmai, Ìä;KapÃŒÃs, L;
2017
28424466
April 19th, 2017
United States
Elson S. Floyd College of Medicine, Department of Biomedical Sciences, Washington State University, Spokane, WA, USA
Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo
Scientific Reports
Hock, AK;Cheung, EC;Humpton, TJ;Monteverde, T;Paulus-Hock, V;Lee, P;McGhee, E;Scopelliti, A;Murphy, DJ;Strathdee, D;Blyth, K;Vousden, KH;
2017
28500323
May 12th, 2017
United Kingdom
Cancer Research UK Beatson Institute, Switchback Road, Glasgow, G61 1BD, UK
Proteomic profiling of the hypothalamus in two mouse models of narcolepsy
Proteomics
Azzam, S;Schlatzer, D;Nethery, D;Saleh, D;Li, X;Akladious, A;Chance, MR;Strohl, KP;
2017
28544614
May 22nd, 2017
United States
Center for Proteomics and Bioinformatics, Department of Nutrition, Case Western Reserve University, Cleveland, OH, USA
Phosphorus Taste Involves T1R2 and T1R3
Chemical Senses
Tordoff, MG;
2017
28383662
June 1st, 2017
United States
Monell Chemical Senses Center, Philadelphia, PA, USA
Enkephalin levels and the number of neuropeptide Y-containing interneurons in the hippocampus are decreased in female cannabinoid-receptor 1 knock-out mice
Neuroscience Letters
Rogers, SA;Kempen, TA;Pickel, VM;Milner, TA;
2016
27012427
May 4th, 2016
United States
Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, 407 East 61st Street, New York, NY 10065, United States
Targeting Tumour Angiogenesis in Colorectal Cancer Liver Metastases
Thesis
Webster, PJ;
2016
May 15th, 2017
England
The University of Leeds
The Na(+)/Ca(2+), K(+) exchanger NCKX4 is required for efficient cone-mediated vision
Elife
Vinberg, F;Wang, T;De Maria, A;Zhao, H;Bassnett, S;Chen, J;Kefalov, VJ;
2017
28650316
June 26th, 2017
United States
Department of Ophthalmology and Visual Sciences, Washington University in St. Louis, St. Louis, United States
Treadmill exercise delays the onset of non-motor behaviors and striatal pathology in the CAG 140 knock-in mouse model of Huntington's disease
Neurobiology of Disease
Stefanko, D;Shah, V;Yamasaki, W;Petzinger, G;Jakowec, M;
2017
May 11th, 2017
United States
Department of Neurology, University of Southern California
PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease
Experimental Neurology
Hsu, WJ;Wildburger, NC;Haidacher, SJ;Nenov, MN;Folorunso, O;Singh, AK;Chesson, BC;Franklin, WF;Cortez, I;Sadygov, RG;Dineley, KT;Rudra, JS;Taglialatela, G;Lichti, CF;Denner, L;Laezza, F;
2017
28522250
May 15th, 2017
United States
Department of Pharmacology & Toxicology, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555, United States; Mitchell Center for Neurodegenerative Diseases, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555, United States; Center for Addiction Research, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555, United States; Center for Biomedical Engineering, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555, United States
Role of ERë± in Mediating Female Uterine Transcriptional Responses to IGF1
Endocrinology
Hewitt, SC;Winuthayanon, W;Lierz, SL;Hamilton, KJ;Donoghue, LJ;Ramsey, JT;Grimm, SA;Arao, Y;Korach, KS;
2017
28586424
June 6th, 2017
United States
Receptor Biology, Reproductive and Developmental Laboratory, National Institute of Environmental Health Sciences, NIH, Research Triangle Park, NC 27709
Functional perturbation of forebrain principal neurons reveals differential effects in novel and well-learned tasks.
Brain Research
Stoneham, ET;McHail, DG;Boggs, KN;Albani, SH;Carty, JA;Evans, RC;Hamilton, KA;Saadat, VM;Hussain, S;Greer, ME;Dumas, TC;
2017
28666957
June 27th, 2017
United States
Department of Molecular Neuroscience, George Mason University, Fairfax, VA, USA
Skeletal Cell YAP And TAZ Redundantly Promote Bone Development By Regulation Of Collagen I Expression And Organization
bioRxiv
Kegelman, CD;Mason, DE;Dawahare, JH;Vigil, GD;Howard, SS;Bellido, TM;Robling, AG;Boerckel, J;
2017
May 30th, 2017
United States
Departments of Orthopaedic Surgery and Bioengineering, University of Pennsylvania
Mechanisms Regulating Growth Progression of Salivary Gland Neoplasms Using Mucoepidermoid Carcenoma Primary Cells
Thesis
Alamri, AM;
2017
April 17th, 2017
United States
N/A
Dopamine neuron dependent behaviors mediated by glutamate cotransmission
bioRxiv
Mingote, S;Chuhma, N;Kalmbach, A;Thomsen, GM;Wang, Y;Mihali, A;Sferrazza, C;Zucker-Scharff, I;Siena, A;Welch, MG;Lizardi-Ortiz, J;Sulzer, D;Moore, H;Gaisler-Salomon, I;Rayport, S;
2017
June 23rd, 2017
United States
Department of Psychiatry, Columbia University
Measuring the olfactory bulb input-output transformation reveals a contribution to the perception of odorant concentration invariance
Nature Communications
Storace, DA;Cohen, LB;
2017
28724907
July 19th, 2017
United States
Department of Cellular and Molecular Physiology, Yale University School of Medicine, 333 Cedar Street, New Haven, Connecticut, 06520, USA
A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism
Nature Communications
Barzi, M;Pankowicz, FP;Zorman, B;Liu, X;Legras, X;Yang, D;Borowiak, M;Bissig-Choisat, B;Sumazin, P;Li, F;Bissig, KD;
2017
28659616
June 28th, 2017
United States
Center for Cell and Gene Therapy, Stem Cells and Regenerative Medicine Center, Baylor College of Medicine, Houston, TX-77030, USA
Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells
Molecular Biology of the Cell
Sui, Z;Gokhin, DS;Nowak, RB;Guo, X;An, X;Fowler, VM;
2017
28720661
July 18th, 2017
United States
Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA, USA
Endothelium-derived fibronectin regulates neonatal vascular morphogenesis in an autocrine fashion
Angiogenesis
Turner, CJ;Badu-Nkansah, K;Hynes, RO;
2017
28667352
June 30th, 2017
United States
Howard Hughes Medical Institute, Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Ave, 76-361, Cambridge, MA, 02139, USA
Monosynaptic retrograde tracing of neurons expressing the G-protein coupled receptor Gpr151 in the mouse brain
The Journal of Comparative Neurology
Broms, J;Grahm, M;Haugegaard, L;Blom, T;Meletis, K;Tingstr̦m, A;
2017
28657115
June 28th, 2017
Sweden
Psychiatric Neuromodulation Unit, Department of Clinical Sciences, Faculty of Medicine, Lund University, Lund, Sweden
Tonotopic alterations in inhibitory input to the medial nucleus of the trapezoid body in a mouse model of Fragile X syndrome
The Journal of Comparative Neurology
McCullagh, EA;Salcedo, E;Huntsman, MM;Klug, A;
2017
28744893
July 26th, 2017
United States
Department of Physiology and Biophysics, University of Colorado School of Medicine, Aurora, CO, USA
The Neural Encoding of Reward in the Striatal-Pallidal Circuitry
Thesis
Chan, CL;
2017
August 1st, 2017
United States
Marquette University
Importance of poly (A)-binding protein 4 (PABP4) in healthy pregnancy
Thesis
Hrabalkova, L;
2016
August 1st, 2017
United Kingdom
University of Edinburgh
Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening
Molecular Cell
Arduino, DM;Wettmarshausen, J;Vais, H;Navas-Navarro, P;Cheng, Y;Leimpek, A;Ma, Z;Delrio-Lorenzo, A;Giordano, A;Garcia-Perez, C;MÌ©dard, G;Kuster, B;GarcÌ_a-Sancho, J;Mokranjac, D;Foskett, JK;Alonso, MT;Perocchi, F;
2017
28820965
August 17th, 2017
Germany
Gene Center/Department of Biochemistry, Ludwig-Maximilians UniversitÌ_t MÌ_nchen, Munich 81377, Germany; Institute for Diabetes and Obesity, Helmholtz Zentrum MÌ_nchen, Neuherberg 85764, Germany
Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance
Nature Communications
Rode, B;Shi, J;Endesh, N;Drinkhill, MJ;Webster, PJ;Lotteau, SJ;Bailey, MA;Yuldasheva, NY;Ludlow, MJ;Cubbon, RM;Li, J;Futers, TS;Morley, L;Gaunt, HJ;Marszalek, K;Viswambharan, H;Cuthbertson, K;Baxter, PD;Foster, R;Sukumar, P;Weightman, A;Calaghan, SC;Wheatcroft, SB;Kearney, MT;Beech, DJ;
2017
28839146
August 24th, 2017
United Kingdom
Schools of Medicine, University of Leeds, Leeds, LS2 9JT, UK
Gemcitabine-induced TIMP1 attenuates therapy response and promotes tumor growth and liver metastasis in pancreatic cancer
Cancer Research
D'Costa, Z;Jones, K;Azad, A;van Stiphout, R;Lim, SY;Gomes, AL;Kinchesh, P;Smart, SC;McKenna, WG;Buffa, FM;Sansom, OJ;Muschel, RJ;O'Neill, E;Fokas, E;
2017
28765154
August 1st, 2017
United Kingdom
Department of Oncology, Oxford Institute for Radiation Oncology and Biology, University of Oxford
The selective Tie2 inhibitor rebastinib blocks recruitment and function of Tie2Hi macrophages in breast cancer and pancreatic neuroendocrine tumors
Molecular Cancer Therapeutics
Harney, AS;Karagiannis, GS;Pignatelli, J;Smith, BD;Kadioglu, E;Wise, SC;Hood, MM;Kaufman, MD;Leary, CB;Lu, WP;Al-Ani, G;Chen, X;Entenberg, D;Oktay, MH;Wang, Y;Chun, L;De Palma, M;Jones, JG;Flynn, DL;Condeelis, JS;
2017
28838996
August 24th, 2017
United States
Department of Anatomy & Structural Biology, Albert Einstein College of Medicine
The Small Rho GTPase TC10 Modulates B Cell Immune Responses
Journal of Immunology
Burbage, M;Keppler, SJ;Montaner, B;Mattila, PK;Batista, FD;
2017
28747344
September 1st, 2017
Finland
Lymphocyte Interaction Laboratory, Francis Crick Institute, London NW1 1AT, United Kingdom
Detection of Maltodextrin and Its Discrimination from Sucrose are Independent of the T1R2+T1R3 Heterodimer
American Journal of Physiology
Smith, KR;Spector, AC;
2017
28768658
August 2nd, 2017
United States
Florida State University
Increased ethanol drinking in humanized mice expressing the mu opioid receptor A118G polymorphism are mediated through sex-specific mechanisms
Brain Research Bulletin
Henderson-Redmond, AN;Lowe, TE;Tian, XB;Morgan, DJ;
2017
28780411
August 2nd, 2017
United States
Department of Anesthesiology & Perioperative Medicine, Penn State University College of Medicine, Hershey, PA 17033, United States
Mutations in the Katnb1 gene cause left-right asymmetry and heart defects
Developmental Dynamics
Furtado, MB;Merriner, DJ;Berger, S;Rhodes, D;Jamsai, D;O'Bryan, MK;
2017
28791777
August 9th, 2017
United States
The Jackson Laboratory, Bar Harbor, Maine, USA
Beneficial Effects of Prebiotic Saccharomyces cerevisiae Mannan on Allergic Asthma Mouse Models
Journal of Immunology Research
Lew, DB;Michael, CF;Overbeck, T;Robinson, WS;Rohman, EL;Lehman, JM;Patel, JK;Eiseman, B;LeMessurier, KS;Samarasinghe, AE;Gaber, MW;
2017
28835901
August 24th, 2017
United States
Department of Pediatrics, University of Tennessee Health Science Center (UTHSC) and Children's Foundation Research Institute, Le Bonheur Children's Hospital, Memphis, TN, USA
Morphology of Dbx1 respiratory neurons in the preB̦tzinger complex and reticular formation of neonatal mice
Scientific Data
Akins, VT;Weragalaarachchi, K;Picardo, MCD;Revill, AL;Del Negro, CA;
2017
28763053
August 1st, 2017
United States
Department of Applied Science, The College of William and Mary, Williamsburg, Virginia 23185, USA
cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation
Neuron
Hwang, HW;Saito, Y;Park, CY;Blachère, NE;Tajima, Y;Fak, JJ;Zucker-Scharff, I;Darnell, RB;
2017
28910620
September 13th, 2017
United States
Laboratory of Molecular Neuro-Oncology and Howard Hughes Medical Institute, The Rockefeller University, 1230 York Avenue, New York, New York 10065, USA; Department of Pathology, University of Pittsburgh, School of Medicine, 3550 Terrace Street, Pittsburgh, PA 15213, USA
Identification of HSP90 inhibitors as a novel class of senolytics
Nature Communications
Fuhrmann-Stroissnigg, H;Ling, YY;Zhao, J;McGowan, SJ;Zhu, Y;Brooks, RW;Grassi, D;Gregg, SQ;Stripay, JL;Dorronsoro, A;Corbo, L;Tang, P;Bukata, C;Ring, N;Giacca, M;Li, X;Tchkonia, T;Kirkland, JL;Niedernhofer, LJ;Robbins, PD;
2017
28871086
September 4th, 2017
United States
Department of Metabolism and Aging, The Scripps Research Institute, Jupiter, 33458, FL, USA
Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes
Cell Reports
Adam, J;Ramracheya, R;Chibalina, MV;Ternette, N;Hamilton, A;Tarasov, AI;Zhang, Q;Rebelato, E;Rorsman, NJG;MartÃn-Del-RÃo, R;Lewis, A;Özkan, G;Do, HW;Spégel, P;Saitoh, K;Kato, K;Igarashi, K;Kessler, BM;Pugh, CW;Tamarit-Rodriguez, J;Mulder, H;Clark, A;Frizzell, N;Soga, T;Ashcroft, FM;Silver, A;Pollard, PJ;Rorsman, P;
2017
28954230
September 26th, 2017
United Kingdom
Radcliffe Department of Medicine, OCDEM, Churchill Hospital, University of Oxford, Oxford OX3 7LE, UK; Nuffield Department of Medicine, Henry Wellcome Building for Molecular Physiology, University of Oxford, Oxford OX3 7BN, UK; Nuffield Department of Medicine, NDMRB, University of Oxford, Oxford OX3 7FZ, UK
Rubrocerebellar feedback loop isolates the interposed nucleus as an independent processor of corollary discharge information in mice
Journal of Neuroscience
Beitzel, CS;Houck, BD;Lewis, SM;Person, AL;
2017
28916520
September 15th, 2017
United States
Department of Physiology & Biophysics, University of Colorado School of Medicine, Aurora, CO 80045
Experience-dependent synaptic plasticity in V1 occurs without microglial CX3CR1
Journal of Neuroscience
Schecter, RW;Maher, EE;Welsh, CA;Stevens, B;Erisir, A;Bear, MF;
2017
28951447
September 26th, 2017
United States
Picower Institute for Learning and Memory, Massachusetts Institute of Technology, Cambridge, United States 02139
Morphine activation of mu opioid receptors causes disinhibition of neurons in the ventral tegmental area mediated by β-arrestin2 and c-Src
Scientific Reports
Bull, FA;Baptista-Hon, DT;Lambert, JJ;Walwyn, W;Hales, TG;
2017
28855588
August 30th, 2017
United Kingdom
The Institute of Academic Anaesthesia, University of Dundee, Dundee, DD1 9SY, UK
Intracellular Chloride Regulation in AVP+ and VIP+ Neurons of the Suprachiasmatic Nucleus
Scientific Reports
Klett, NJ;Allen, CN;
2017
28860458
August 31st, 2017
United States
Oregon Institute for Occupational Health Sciences, School of Medicine, Oregon Health & Science University, Portland, OR, 97239, USA
Intravenous treatment with human recombinant ApoA-I Milano reduces beta amyloid cerebral deposition in the APP23-transgenic mouse model of Alzheimer's disease
Neurobiology of Aging
Fernández-de Retana, S;Montañola, A;Marazuela, P;De La Cuesta, M;Batlle, A;Fatar, M;Grudzenski, S;Montaner, J;Hernández-Guillamon, M;
2017
28941727
September 5th, 2017
Spain
Neurovascular Research Laboratory, Vall d'Hebron Research Insitute, Universitat Autònoma de Barcelona, Barcelona, Spain
Inflammation alters AMPA-stimulated calcium responses in dorsal striatal D2 but not D1 spiny projection neurons
European Journal of Neuroscience
Winland, CD;Welsh, N;Sepulveda-Rodriguez, A;Vicini, S;Maguire-Zeiss, KA;
2017
28921719
September 16th, 2017
United States
Interdisciplinary Program in Neuroscience, Georgetown University Medical Center, Washington, D.C, 20007, USA
Pazopanib Reduces Phosphorylated Tau Levels and Alters Astrocytes in a Mouse Model of Tauopathy
Journal of Alzheimers Disease
Javidnia, M;Hebron, ML;Xin, Y;Kinney, NG;Moussa, CE;
2017
28869476
September 4th, 2017
United States
Department of Neurology, Laboratory for Dementiaand Parkinsonism, Translational Neurotherapeutics Program, Washington, DC, USA
Histone chaperone HIRA deposits histone H3. 3 onto foreign viral DNA and contributes to anti-viral intrinsic immunity
Nucleic Acids Research
Rai, TS;Glass, M;Cole, JJ;Rather, MI;Marsden, M;Neilson, M;Brock, C;Humphreys, IR;Everett, RD;Adams, PD;
2017
September 13th, 2017
United States
Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037, USA
Reliable sensory processing in mouse visual cortex through inhibitory interactions between Somatostatin and Parvalbumin interneurons
bioRxiv
Rikhye, RV;Hu, M;Yildirim, M;Sur, M;
2017
September 11th, 2017
United States
Picower Institute for Learning and Memory, Massachusetts Institute of Technology Cambridge, Massachusetts 02139
Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes
Frontiers in Immunology
McDonald, G;Medina, CO;Pilichowska, M;Kearney, JF;Shinkura, R;Selsing, E;Wortis, HH;Honjo, T;Imanishi-Kari, T;
2017
28955333
September 28th, 2017
United States
Department of Integrative Physiology and Pathobiology, Sackler School of Graduate Biomedical Sciences, Tufts University School of Medicine, Boston, MA, United States
Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration.
Neuron
Pease-Raissi, SE;Pazyra-Murphy, MF;Li, Y;Wachter, F;Fukuda, Y;Fenstermacher, SJ;Barclay, LA;Bird, GH;Walensky, LD;Segal, RA;
2017
29024661
October 11th, 2017
United States
Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA; Departments of Cancer Biology and Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA
Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression
The Journal of Clinical Investigation‰
Guo, P;Poulos, MG;Palikuqi, B;Badwe, CR;Lis, R;Kunar, B;Ding, BS;Rabbany, SY;Shido, K;Butler, JM;Rafii, S;
2017
29058691
October 23rd, 2017
United States
Department of Medicine, Division of Regenerative Medicine, Ansary Stem Cell Institute, Weill Cornell Medicine, New York, New York, USA
Dephosphorylation by protein phosphatase 2A regulates visual pigment regeneration and the dark adaptation of mammalian photoreceptors
Proceedings of the National Academy of Sciences of the United States of America
Kolesnikov, AV;Orban, T;Jin, H;Brooks, C;Hofmann, L;Dong, Z;Sokolov, M;Palczewski, K;Kefalov, VJ;
2017
29078372
October 23rd, 2017
United States
Department of Pharmacology, Case Western Reserve University, Cleveland, OH 44106
Molecular architecture underlying fluid absorption by the developing inner ear
Elife
Honda, K;Kim, SH;Kelly, MC;Burns, JC;Constance, L;Li, X;Zhou, F;Hoa, M;Kelley, MW;Wangemann, P;Morell, RJ;Griffith, AJ;
2017
28994389
October 10th, 2017
United States
Molecular Biology and Genetics Section, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, United States
Analysis of Nkx3.1:Cre-driven Erk5 deletion reveals a profound spinal deformity which is linked to increased osteoclast activity
Scientific Reports
Loveridge, CJ;van 't Hof, RJ;Charlesworth, G;King, A;Tan, EH;Rose, L;Daroszewska, A;Prior, A;Ahmad, I;Welsh, M;Mui, EJ;Ford, C;Salji, M;Sansom, O;Blyth, K;Leung, HY;
2017
29038439
October 16th, 2017
United Kingdom
Institute of Ageing and Chronic Disease, University of Liverpool, WH Duncan Building, West Derby Street, Liverpool, L7 8TX, UK
Sim1 neurons are sufficient for MC4R-mediated sexual function in male mice
Endocrinology
Semple, E;Hill, JW;
2017
29059347
October 19th, 2017
United States
University of Toledo College of Medicine and Life Sciences, Department of Physiology and Pharmacology
The caspase-8/RIPK3 signaling axis in antigen presenting cells controls the inflammatory arthritic response
Arthritis Research and Therapy
Dominguez, S;Montgomery, AB;Haines, GK;Bloomfield, CL;Cuda, CM;
2017
28978351
October 4th, 2017
United States
Department of Medicine, Division of Rheumatology, Northwestern University, Feinberg School of Medicine, 240 East Huron Street, M300, Chicago, IL, 60611, USA
Characterising the Role of mTORC1 in Myeloid Cells
Thesis
Yamani, LZ;
2017
January 1st, 2017
England
Queen Mary University of London
Activation of the Aryl Hydrocarbon Receptor Interferes with Early Embryonic Development
Stem Cell Reports
Gialitakis, M;Tolaini, M;Li, Y;Pardo, M;Yu, L;Toribio, A;Choudhary, JS;Niakan, K;Papayannopoulos, V;Stockinger, B;
2017
November 14th, 2017
N/A
The Francis Crick Institute
CXCR2-Dependent Accumulation of Tumor-Associated Neutrophils Regulates T-cell Immunity in Pancreatic Ductal Adenocarcinoma
Cancer Immunology Research
Chao, T;Furth, EE;Vonderheide, RH;
2016
27737879
November 1st, 2016
United States
Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania
Chronic Stress Alters Striosome-Circuit Dynamics, Leading to Aberrant Decision-Making
Cell
Friedman, A;Homma, D;Bloem, B;Gibb, LG;Amemori, KI;Hu, D;Delcasso, S;Truong, TF;Yang, J;Hood, AS;Mikofalvy, KA;Beck, DW;Nguyen, N;Nelson, ED;Toro Arana, SE;Vorder Bruegge, RH;Goosens, KA;Graybiel, AM;
2017
29149606
November 16th, 2017
United States
McGovern Institute for Brain Research and Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
IRF3 and type I interferons fuel a fatal response to myocardial infarction
Nature Medicine
King, KR;Aguirre, AD;Ye, YX;Sun, Y;Roh, JD;Ng, RP;Kohler, RH;Arlauckas, SP;Iwamoto, Y;Savol, A;Sadreyev, RI;Kelly, M;Fitzgibbons, TP;Fitzgerald, KA;Mitchison, T;Libby, P;Nahrendorf, M;Weissleder, R;
2017
29106401
November 6th, 2017
United States
Center for Systems Biology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
Bim suppresses the development of SLE by limiting myeloid inflammatory responses
Journal of Experimental Medicine
Tsai, F;Homan, PJ;Agrawal, H;Misharin, AV;Abdala-Valencia, H;Haines, GK;Dominguez, S;Bloomfield, CL;Saber, R;Chang, A;Mohan, C;Hutcheson, J;Davidson, A;Budinger, GRS;Bouillet, P;Dorfleutner, A;Stehlik, C;Winter, DR;Cuda, CM;Perlman, H;
2017
29114065
December 4th, 2017
United States
Division of Rheumatology, Feinberg School of Medicine, Northwestern University, Chicago, IL
Staphylococcus aureus Epicutaneous Exposure Drives Skin Inflammation via IL-36-Mediated T Cell Responses.
Cell Host Microbe
Liu, H;Archer, NK;Dillen, CA;Wang, Y;Ashbaugh, AG;Ortines, RV;Kao, T;Lee, SK;Cai, SS;Miller, RJ;Marchitto, MC;Zhang, E;Riggins, DP;Plaut, RD;Stibitz, S;Geha, RS;Miller, LS;
2017
29120743
November 8th, 2017
United States
Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA; Department of Medicine, Division of Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA; Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA; Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, MD 21218, USA
HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury
Proceedings of the National Academy of Sciences of the United States of America
Magnani, ND;Dada, LA;Queisser, MA;Brazee, PL;Welch, LC;Anekalla, KR;Zhou, G;Vagin, O;Misharin, AV;Budinger, GRS;Iwai, K;Ciechanover, AJ;Sznajder, JI;
2017
29109255
November 21st, 2017
Israel
Rappaport Faculty of Medicine and Research Institute, Technion Integrated Cancer Center, Haifa, Israel 3109601
Characterization of ApoJ-reconstituted high-density lipoprotein (rHDL) nanodisc for the potential treatment of cerebral β-amyloidosis
Scientific Reports
Fernández-de-Retana, S;Cano-Sarabia, M;Marazuela, P;Sánchez-Quesada, JL;Garcia-Leon, A;Montañola, A;Montaner, J;Maspoch, D;Hernández-Guillamon, M;
2017
29116115
November 7th, 2017
Spain
Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and the Barcelona Institute of Science and Technology, Campus UAB, Bellaterra, Barcelona, Spain
In vivo evidence that RBM5 is a tumour suppressor in the lung
Scientific Reports
Jamsai, D;Watkins, DN;O'Connor, AE;Merriner, DJ;Gursoy, S;Bird, AD;Kumar, B;Miller, A;Cole, TJ;Jenkins, BJ;O'Bryan, MK;
2017
29176597
November 24th, 2017
United States
The School of Biological Sciences, Monash University, 25 Rainforest Walk, Clayton, Victoria, 3800, Australia
Accumulation of rest deficiency precedes sudden death of epileptic Kv1.1 knockout mice, a model of sudden unexpected death in epilepsy
Epilepsia
Iyer, SH;Matthews, SA;Simeone, TA;Maganti, R;Simeone, KA;
2017
29193044
November 28th, 2017
United States
Department of Pharmacology, Creighton University School of Medicine, Omaha, NE, USA
Targeted deletion of câ€Met in thymic epithelial cells leads to an autoimmune phenotype
Immunology and Cell Biology
Su, M;Hu, R;Song, Y;Liu, Y;Lai, L;
2017
December 3rd, 2017
United States
Department of Allied Health Sciences, University of Connecticut
Brain-derived neurotrophic factor (BDNF) determines a sex difference in cue-conditioned alcohol seeking in rats.
Behavioral Brain Research
Hogarth, SJ;Jaehne, EJ;van den Buuse, M;Djouma, E;
2017
29158111
November 21st, 2017
Australia
School of Life Sciences, Department of Physiology, Anatomy and Microbiology, La Trobe University, Bundoora, Australia
Growth Differentiation Factor 11 does not Mitigate the Lethal Effects of Total-Abdominal Irradiation
Radiation Research
Duhachek-Muggy, S;Bhat, K;Vlashi, E;Pajonk, F;
2017
28829672
November 1st, 2017
United States
a   Department of Radiation Oncology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California
Katanin-like 2 (KATNAL2) functions in multiple aspects of haploid male germ cell development in the mouse
PLOS Genetics
Dunleavy, JEM;Okuda, H;O'Connor, AE;Merriner, DJ;O'Donnell, L;Jamsai, D;Bergmann, M;O'Bryan, MK;
2017
29136647
November 1st, 2017
United States
School of Biological Sciences, Monash University, Melbourne, Victoria; Australia
Testosterone replacement in transgenic sickle cell mice controls priapic activity and upregulates PDE5 expression and eNOS activity in the penis
Andrology
Musicki, B;Karakus, S;Akakpo, W;Silva, FH;Liu, J;Chen, H;Zirkin, BR;Burnett, AL;
2017
29145710
November 16th, 2017
United States
The James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins School of Medicine, Baltimore, MD, USA
Mode of Surgical Injury Influences the Source of Urothelial Progenitors during Bladder Defect Repair
Stem Cell Reports
Schäfer, FM;Algarrahi, K;Savarino, A;Yang, X;Seager, C;Franck, D;Costa, K;Liu, S;Logvinenko, T;Adam, R;Mauney, JR;
2017
29173895
November 17th, 2017
United States
Urological Diseases Research Center, Boston Children's Hospital, Boston, MA 02115, USA; Department of Surgery, Harvard Medical School, Boston, MA 02115, USA
Dose-Dependent Rescue of KO Amelogenin Enamel by Transgenes in Vivo.
Frontiers in Physiology
Bidlack, FB;Xia, Y;Pugach, MK;
2017
29201008
November 16th, 2017
United States
Forsyth Institute, Cambridge, MA, United States
Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents.
Nature
Gao, X;Tao, Y;Lamas, V;Huang, M;Yeh, WH;Pan, B;Hu, YJ;Hu, JH;Thompson, DB;Shu, Y;Li, Y;Wang, H;Yang, S;Xu, Q;Polley, DB;Liberman, MC;Kong, WJ;Holt, JR;Chen, ZY;Liu, DR;
2017
29258297
December 20th, 2017
United States
Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA
ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs
Nature Cell Biology
Hicks, MR;Hiserodt, J;Paras, K;Fujiwara, W;Eskin, A;Jan, M;Xi, H;Young, CS;Evseenko, D;Nelson, SF;Spencer, MJ;Handel, BV;Pyle, AD;
2018
29255171
January 1st, 2018
United States
Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research, University of California, Los Angeles, CA, USA
Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis
Nature Communications
Espana-Agusti, J;Warren, A;Chew, SK;Adams, DJ;Matakidou, A;
2017
29229903
December 11th, 2017
United States
Department of Oncology, University of Cambridge, CRUK Cambridge institute, Cambridge, CB2 0RE, UK
CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis
Developmental Cell
Smith, MD;Harley, ME;Kemp, AJ;Wills, J;Lee, M;Arends, M;von Kriegsheim, A;Behrends, C;Wilkinson, S;
2017
29290589
December 27th, 2017
United Kingdom
Edinburgh Cancer Research UK Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XR, UK
STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis
Cell Reports
Ahn, J;Son, S;Oliveira, SC;Barber, GN;
2017
29281834
December 26th, 2017
United States
Department of Cell Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA
The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury
Journal of Immunology
Campana, L;Starkey Lewis, PJ;Pellicoro, A;Aucott, RL;Man, J;O'Duibhir, E;Mok, SE;Ferreira-Gonzalez, S;Livingstone, E;Greenhalgh, SN;Hull, KL;Kendall, TJ;Vernimmen, D;Henderson, NC;Boulter, L;Gregory, CD;Feng, Y;Anderton, SM;Forbes, SJ;Iredale, JP;
2017
29263216
December 20th, 2017
United Kingdom
Medical Research Council Centre for Inflammation Research, University of Edinburgh, Edinburgh EH16 4TJ, United Kingdom
Kif1bp loss in mice leads to defects in the peripheral and central nervous system and perinatal death
Scientific Reports
Hirst, CS;Stamp, LA;Bergner, AJ;Hao, MM;Tran, MX;Morgan, JM;Dutschmann, M;Allen, AM;Paxinos, G;Furlong, TM;McKeown, SJ;Young, HM;
2017
29192291
November 30th, 2017
United States
Department of Anatomy and Neuroscience, The University of Melbourne, Victoria, 3010, Australia
Neuronal CCL2 expression drives inflammatory monocyte infiltration into the brain during acute virus infection
Journal of Neuroinflammation
Howe, CL;LaFrance-Corey, RG;Goddery, EN;Johnson, RK;Mirchia, K;
2017
29202854
December 4th, 2017
United States
Translational Neuroimmunology Lab, Mayo Clinic, Rochester, USA
Fatty acid binding protein 5 mediates the uptake of fatty acids, but not drugs, into human brain endothelial cells
Journal of Pharmaceutical Sciences
Lee, GS;Pan, Y;Scanlon, MJ;Porter, CJH;Nicolazzo, JA;
2017
29247738
December 13th, 2017
United States
Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia
The Endosomal-Lysosomal Pathway is Dysregulated by APOE4 Expression In Vivo
Frontiers in Neuroscience
Nuriel, T;Peng, KY;Ashok, A;Dillman, AA;Figueroa, HY;Apuzzo, J;Ambat, J;Levy, E;Cookson, MR;Mathews, PM;Duff, KE;
2017
December 12th, 2017
United States
Department of Pathology and Cell Biology, Taub Institute for Research of Alzheimer's Disease and the Aging Brain, Columbia University Medical Center, Colombia University, New York, NY, United States
HSCB, a Co-chaperone in Mitochondrial Iron-Sulfur Cluster Biogenesis, is a Novel Candidate Gene for Congenital Sideroblastic Anemia
Thesis
Crispin, A;
2017
United States
Boston University
Single point mutation on the gene encoding dysbindin results in recognition deficits
Brain and Behavior
Chang, EH;Fernando, K;Yeung, LWE;Barbari, K;Chandon, TS;Malhotra, AK;
2017
29227583
December 11th, 2017
United States
Center for Psychiatric Neuroscience, The Feinstein Institute for Medical Research, Northwell Health, 350 Community Drive, Manhasset, NY, 11030, USA
Consistent hypersocial behavior in mice carrying a deletion of Gtf2i but no evidence of hyposocial behavior with Gtf2i duplication: Implications for Williams–Beuren syndrome and autism spectrum disorder
Brain and Behavior
Martin, LA;Iceberg, E;Allaf, G;
2017
December 19th, 2017
Department of Graduate Psychology, Azusa Pacific University, Azusa, CA, USA
Department of Graduate Psychology, Azusa Pacific University, Azusa, CA, USA
Bimodal RMS distributions for the objective detection of theta (θ) and gamma (γ) brain oscillations during long-term continuous LFP recordings in mice
MACRo 2015
Molnar, L;Domokos, J;Ferando, I;Mody, I;
2017
December 21st, 2017
Romania
Department of Electrical Engineering, Faculty of Technical and Human Sciences, Sapientia University, Tg
Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration
Nature
Raven, A;Lu, WY;Man, TY;Ferreira-Gonzalez, S;O'Duibhir, E;Dwyer, BJ;Thomson, JP;Meehan, RR;Bogorad, R;Koteliansky, V;Kotelevtsev, Y;Ffrench-Constant, C;Boulter, L;Forbes, SJ;
2017
28700576
July 20th, 2017
France
MRC Centre for Regenerative Medicine, University of Edinburgh, 5 Little France Drive, Edinburgh EH16 4UU, UK
Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors
Proceedings of the National Academy of Sciences of the United States of America
Djurec, M;Graña, O;Lee, A;Troulé, K;Espinet, E;Cabras, L;Navas, C;Blasco, MT;MartÃn-DÃaz, L;Burdiel, M;Li, J;Liu, Z;Vallespinós, M;Sanchez-Bueno, F;Sprick, MR;Trumpp, A;Sainz, B;Al-Shahrour, F;Rabadan, R;Guerra, C;Barbacid, M;
2018
29351990
January 19th, 2018
Spain
Molecular Oncology, Centro Nacional de Investigaciones Oncológicas (CNIO), 28029 Madrid, Spain
Targeting multiple effector pathways in pancreatic ductal adenocarcinoma with a G-quadruplex-binding small molecule
Journal of Medicinal Chemistry
Marchetti, C;Zyner, KG;Ohnmacht, SA;Robson, M;Haider, SM;Morton, JP;Marsico, G;Vo, T;Laughlin-Toth, S;Ahmed, AA;Di Vita, G;Pazitna, I;Gunaratnam, M;Besser, RJ;Andrade, AC;Diocou, S;Pike, JA;Tannahill, D;Pedley, RB;Evans, TRJ;Wilson, WD;Balasubramanian, S;Neidle, S;
2018
29356532
January 22nd, 2018
United Kingdom
UCL School of Pharmacy, University College London, 29-39 Brunswick Square, London WC1N 1AX, UK
Neurogenesis during abstinence is necessary for context-driven methamphetamine-related memory
Journal of Neuroscience
Galinato, MH;Takashima, Y;Fannon, MJ;Quach, LW;Morales Silva, RJ;Mysore, KK;Terranova, MJ;Dutta, RR;Ostrom, RW;Somkuwar, SS;Mandyam, CD;
2018
29363584
January 23rd, 2018
United States
Department of Neuroscience, University of California San Diego, San Diego, CA, USA
Skeletal cell YAP and TAZ combinatorially promote bone development
The FASEB Journal
Kegelman, C;Mason, D;Dawahare, J;Horan, D;Vigil, G;Howard, S;Robling, A;Bellido, T;Boerckel, J;
2018
January 10th, 2018
United States
Department of Orthopaedic Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
Respiratory dysfunction progresses with age in Kcna1-null mice, a model of sudden unexpected death in epilepsy
Epilepsia
Simeone, KA;Hallgren, J;Bockman, CS;Aggarwal, A;Kansal, V;Netzel, L;Iyer, SH;Matthews, SA;Deodhar, M;Oldenburg, PJ;Abel, PW;Simeone, TA;
2018
29327348
January 12th, 2018
United States
Department of Pharmacology, Creighton University School of Medicine, Omaha, NE, USA
Transcriptomic analysis of gene signatures associated with sickle pain
Scientific Data
Paul, JA;Aich, A;Abrahante, JE;Wang, Y;LaRue, RS;Rathe, SK;Kalland, K;Mittal, A;Jha, R;Peng, F;Largaespada, DA;Bagchi, A;Gupta, K;
2017
29292796
May 16th, 2017
United States
Vascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota, Minneapolis, Minnesota 55455, USA
The large-conductance voltage- and Ca2+ -activated K+ channel and its γ1 subunit modulate mouse uterine artery function during pregnancy
Journal of Physiology (London)
Lorca, RA;Wakle-Prabagaran, M;Freeman, WE;Pillai, MK;England, SK;
2018
29319186
January 10th, 2018
United States
Center for Reproductive Health Sciences, Department of Obstetrics and Gynecology, Washington University in St. Louis School of Medicine, St. Louis, MO, 63110, USA
Oxytocin and the warm outer glow: Thermoregulatory deficits cause huddling abnormalities in oxytocin-deficient mouse pups
Hormones and Behavior
Harshaw, C;Leffel, JK;Alberts, JR;
2018
29277701
January 4th, 2018
United States
Department of Psychology, University of New Orleans, New Orleans, LA, United States; Department of Psychological & Brain Sciences, Indiana University, Bloomington, IN, United States
Pazopanib Reduces Tau Pathology and Restores Astrocytes in a Novel Mouse Model of Neurodegenerative Tauopathy
Thesis
Javidnia, M;
2017
October 20th, 2017
United States
Georgetown University
A Braf kinase-inactive mutant induces lung adenocarcinoma
Nature
Nieto, P;Ambrogio, C;Esteban-Burgos, L;Gómez-López, G;Blasco, MT;Yao, Z;Marais, R;Rosen, N;Chiarle, R;Pisano, DG;Barbacid, M;SantamarÃa, D;
2017
28783725
August 10th, 2017
Spain
Experimental Oncology, Molecular Oncology Programme, Centro Nacional de Investigaciones Oncológicas (CNIO), 28029 Madrid, Spain
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
Nature Medicine
Bartelt, A;Widenmaier, SB;Schlein, C;Johann, K;Goncalves, RLS;Eguchi, K;Fischer, AW;Parlakgül, G;Snyder, NA;Nguyen, TB;Bruns, OT;Franke, D;Bawendi, MG;Lynes, MD;Leiria, LO;Tseng, YH;Inouye, KE;Arruda, AP;Hotamisligil, GS;
2018
29400713
February 5th, 2018
United States
Department of Genetics and Complex Diseases and Sabri Ãœlker Center, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA
Delayed Degradation and Impaired Dendritic Delivery of Intron-LackingEGFP-Arc/Arg3.1mRNA inEGFP-ArcTransgenic Mice
Frontiers in Molecular Neuroscience
Steward, O;Matsudaira Yee, K;Farris, S;Pirbhoy, PS;Worley, P;Okamura, K;Okuno, H;Bito, H;
2017
29445324
January 31st, 2017
United States
Reeve-Irvine Research Center, University of California, Irvine, Irvine, CA, United States
The Bcl-2 Homology-3 Domain (BH3)-Only Proteins, Bid, DP5/Hrk, and BNip3L, Are Upregulated in Reactive Astrocytes of End-Stage Mutant SOD1 Mouse Spinal Cord
Frontiers in Cellular Neuroscience
Duval, N;Sumner, WA;Andrianakos, AG;Gray, JJ;Bouchard, RJ;Wilkins, HM;Linseman, DA;
2018
29440992
January 30th, 2018
United States
Biological Sciences and Knoebel Institute for Healthy Aging, University of Denver, Denver, CO, United States
The Complement System Is Critical in Maintaining Retinal Integrity during Aging
Frontiers in Aging Neuroscience
Mukai, R;Okunuki, Y;Husain, D;Kim, C;Lambris, J;Connor, K;
2018
February 15th, 2018
United States
Angiogenesis Laboratory, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Harvard University, Boston, MA, United States
Water transport and homeostasis as a major function of erythrocytes
American Journal of Physiology Heart and Circulatory Physiology
Sugie, J;Intaglietta, M;Sung, LA;
2018
29393658
February 2nd, 2018
United States
Bioengineering, UCSD, United States
Taste sensitivity to a mixture of monosodium glutamate and inosine 5'-monophosphate by mice lacking both subunits of the T1R1+T1R3 amino acid receptor
American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Blonde, GD;Travers, SP;Spector, AC;
2018
29443544
February 14th, 2018
United States
Department of Psychology, Florida State University, United States
Gain-of-function and dominant-negative effects of distinct p53 mutations in lung tumours
Thesis
Turrell, FK;
2018
December 1st, 2017
United Kingdom
University of Cambridge
Development of T cell based therapeutic strategies for childhood cancer neuroblastoma
Thesis
Turrell, FK;
2017
United Kingdom
University College London
INSL5 activates multiple signalling pathways and regulates GLP-1 secretion in NCI-H716 cells
Journal of Molecular Endocrinology
Ang, SY;Evans, BA;Poole, DP;Bron, R;DiCello, JJ;Bathgate, RAD;Kocan, M;Hutchinson, DS;Summers, RJ;
2018
29535183
April 1st, 2018
United States
Drug Discovery BiologyMonash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia
Evidence of Wnt/β-Catenin alterations in brain and bone of a tauopathy mouse model of Alzheimer’s disease
Neurobiology of Aging
Dengler-Crish, C;Ball, H;Lin, L;Novak, K;Cooper, L;
2018
March 1st, 2018
United States
Department of Pharmaceutical Sciences Northeast Ohio Medical University 4209 State Route 44 Rootstown, OH 44272
The vulnerability of spinal motoneurons and soma size plasticity in a mouse model of amyotrophic lateral sclerosis
The Journal of Physiology
Dukkipati, SS;Garrett, TL;Elbasiouny, SM;
2018
29502344
March 4th, 2018
United States
Department of Neuroscience, Cell Biology, and Physiology, Boonshoft School of Medicine and College of Science and Mathematics, Wright State University, Dayton, OH 45435, USA
Paracrine cellular senescence exacerbates biliary injury and impairs regeneration
Nature Communications
Ferreira-Gonzalez, S;Lu, WY;Raven, A;Dwyer, B;Man, TY;O'Duibhir, E;Lewis, PJS;Campana, L;Kendall, TJ;Bird, TG;Tarrats, N;Acosta, JC;Boulter, L;Forbes, SJ;
2018
29523787
March 9th, 2018
France
MRC Centre for Regenerative Medicine, University of Edinburgh, 5 Little France Drive, Edinburgh, EH16 4UU, UK
Dopamine D2 Receptors in Dopaminergic Neurons Modulate Performance in a Reversal Learning Task in Mice
eNeuro
Linden, J;James, AS;McDaniel, C;Jentsch, JD;
2018
29527566
March 8th, 2018
United States
State University of New York at Binghamton, Binghamton, NY 13902
Consistent hypersocial behavior in mice carrying a deletion ofGtf2ibut no evidence of hyposocial behavior withGtf2iduplication: Implications for Williams-Beuren syndrome and autism spectrum disorder
Brain and Behavior
Martin, LA;Iceberg, E;Allaf, G;
2018
29568691
January 1st, 2018
United States
Department of Graduate PsychologyAzusa Pacific UniversityAzusaCAUSA
Characteristics of cellular and synaptic function in rodent forebrain neurons with altered SynGAP expression
Thesis
Mizen, LAMT;
2018
N/A
N/A
Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay
Proceedings of the National Academy of Sciences of the United States of America
Nguyen, AD;Nguyen, TA;Zhang, J;Devireddy, S;Zhou, P;Karydas, AM;Xu, X;Miller, BL;Rigo, F;Ferguson, SM;Huang, EJ;Walther, TC;Farese, RV;
2018
29511098
March 20th, 2018
United States
Department of Genetics and Complex Diseases, Harvard T. H. Chan School of Public Health, Boston, MA 02115
Sprouty2 loss-induced IL6 drives castration-resistant prostate cancer through scavenger receptor B1
EMBO Molecular Medicine
Patel, R;Fleming, J;Mui, E;Loveridge, C;Repiscak, P;Blomme, A;Harle, V;Salji, M;Ahmad, I;Teo, K;Hamdy, FC;Hedley, A;van den Broek, N;Mackay, G;Edwards, J;Sansom, OJ;Leung, HY;
2018
29540470
March 14th, 2018
United Kingdom
Cancer Research UK Beatson Institute, Glasgow, UK
Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer's disease
Molecular Neurodegeneration
Sosna, J;Philipp, S;Albay, R;Reyes-Ruiz, JM;Baglietto-Vargas, D;LaFerla, FM;Glabe, CG;
2018
29490706
March 1st, 2018
United States
Department of Molecular Biology and Biochemistry, University of California, Irvine, USA
PI3Kδ hyper-activation promotes the development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner
bioRxiv
Stark, A;Chandra, A;Chakraborty, K;Alam, R;Carbonaro, V;Clark, J;Sriskantharajah, S;Bradley, G;Richter, A;Banham-Hall, E;Clatworthy, M;Nejentsev, S;Hamblin, J;Hessel, E;Condliffe, A;Okkenhaug, K;
2018
March 18th, 2018
United States
Laboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge CB21 3AT, UK
Phospho-regulation of Atoh1 is required for plasticity of secretory progenitors and tissue regeneration
bioRxiv
Tomic, G;Morrissey, E;Kozar, S;Ben-Moshe, S;Hoyle, A;Azzarelli, R;Kemp, R;Chilamakuri, C;Itzkovitz, S;Philpott, A;Winton, D;
2018
February 27th, 2018
United States
Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge CB2 0RE, UK
Impact of X/Y genes and sex hormones on mouse neuroanatomy
Neuroimage
Vousden, DA;Corre, C;Spring, S;Qiu, LR;Metcalf, A;Cox, E;Lerch, JP;Palmert, MR;
2018
29501873
March 2nd, 2018
Canada
Mouse Imaging Centre and Program in Neuroscience and Mental Health, The Hospital for Sick Children, 25 Orde Street, Toronto, ON, M5T 3H7, Canada; Department of Medical Biophysics, The University of Toronto, 101 College Street, Suite 15-701, Toronto, ON, M5G 1L7, Canada
Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells
Cancer Cell
Ahn, J;Xia, T;Rabasa Capote, A;Betancourt, D;Barber, G;
2018
April 1st, 2018
United States
Department of Cell Biology, The University of Miami Miller School of Medicine, University of Miami, 511 Papanicolaou Building, 1550 NW 10th Avenue, Miami, FL 33136, USA
An Autoimmune Basis for Raynaud's Phenomenon: Murine Model and Human Disease
Arthritis & Rheumatology
Ascherman, DP;Zang, Y;Fernandez, I;Clark, ES;Khan, WN;Martinez, L;Greidinger, EL;
2018
29569858
March 23rd, 2018
United States
Miami VA Medical Center
Evidence of Wnt/β-catenin alterations in brain and bone of a tauopathy mouse model of Alzheimer's disease
Neurobiology of Aging
Dengler-Crish, CM;Ball, HC;Lin, L;Novak, KM;Cooper, LN;
2018
29660685
March 23rd, 2018
United States
Department of Pharmaceutical Sciences, Northeast Ohio Medical University, Rootstown, OH, USA
Activity-dependent modulation of hippocampal synaptic plasticity via PirB and endocannabinoids
Molecular Psychiatry
Djurisic, M;Brott, BK;Saw, NL;Shamloo, M;Shatz, CJ;
2018
29670176
April 18th, 2018
United States
Departments of Biology and Neurobiology, and Bio-X, Stanford University, Stanford, CA, 94305, USA
Galectins Control mTOR in Response to Endomembrane Damage
Molecular Cell
Jia, J;Abudu, YP;Claude-Taupin, A;Gu, Y;Kumar, S;Choi, SW;Peters, R;Mudd, MH;Allers, L;Salemi, M;Phinney, B;Johansen, T;Deretic, V;
2018
29625033
April 5th, 2018
United States
Autophagy Inflammation and Metabolism Center of Biomedical Research Excellence, University of New Mexico Health Sciences Center, 915 Camino de Salud, NE, Albuquerque, NM 87131, USA; Department of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, 915 Camino de Salud, NE, Albuquerque, NM 87131, USA
The ERBB network facilitates KRAS-driven lung tumorigenesis
bioRxiv
Kruspig, B;Monteverde, T;Neidler, S;Hock, A;Kerr, E;Nixon, C;Clark, W;Hedley, A;Dick, C;Vousden, K;Martins, C;Murphy, D;
2018
April 9th, 2018
United Kingdom
Institute of Cancer Sciences, University of Glasgow, U.K
SOX11 augments BCR signaling to drive MCL-like tumor development
Blood
Kuo, PY;Jatiani, SS;Rahman, AH;Edwards, D;Jiang, Z;Ahr, K;Perumal, D;Leshchenko, VV;Brody, J;Shaknovich, R;Ye, BH;Parekh, S;
2018
29615403
April 3rd, 2018
United States
Hematology and Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY, United States
The role of CX3CR1 in pancreatic cancer
Thesis
Li Causi, E;
2018
N/A
N/A
CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes
Neuron
Ma, Z;Taruno, A;Ohmoto, M;Jyotaki, M;Lim, JC;Miyazaki, H;Niisato, N;Marunaka, Y;Lee, RJ;Hoff, H;Payne, R;Demuro, A;Parker, I;Mitchell, CH;Henao-Mejia, J;Tanis, JE;Matsumoto, I;Tordoff, MG;Foskett, JK;
2018
29681531
April 13th, 2018
United States
Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Type-2 diabetic aldehyde dehydrogenase 2 mutant mice (ALDH 2*2) exhibiting heart failure with preserved ejection fraction phenotype can be determined by exercise stress echocardiography
PLOS ONE
Pan, G;Munukutla, S;Kar, A;Gardinier, J;Thandavarayan, RA;Palaniyandi, SS;
2018
29677191
April 20th, 2018
United States
Division of Hypertension and Vascular Research, Department of Internal Medicine, Henry Ford Health System, Detroit, MI United States of America
Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging
Redox Biology
Robinson, A;Yousefzadeh, M;Rozgaja, T;Wang, J;Li, X;Tilstra, J;Feldman, C;Gregg, S;Johnson, C;Skoda, E;Frantz, M;Bell-Temin, H;Pope-Varsalona, H;Gurkar, A;Nasto, L;Robinson, R;Fuhrmann-Stroissnigg, H;Czerwinska, J;McGowan, S;Cantu-Medellin, N;Harris, J;Maniar, S;Ross, M;Trussoni, C;LaRusso, N;Cifuentes-Pagano, E;Pagano, P;Tudek, B;Vo, N;Rigatti, L;Opresko, P;Beer-Stolz, D;Watkins, S;Burd, C;Croix, C;Siuzdak, G;Yates, N;Robbins, P;Wang, Y;Wipf, P;Kelley, E;Niedernhofer, L;
2018
April 1st, 2018
United States
Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, 15261, USA
Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M
Nature Communications
Sampath, SC;Sampath, SC;Ho, ATV;Corbel, SY;Millstone, JD;Lamb, J;Walker, J;Kinzel, B;Schmedt, C;Blau, HM;
2018
29670077
April 18th, 2018
United States
Baxter Laboratory for Stem Cell Biology, Department of Microbiology and Immunology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, CA, 94305, USA
The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia
Cell Metabolism
Sim, J;Cowburn, AS;Palazon, A;Madhu, B;Tyrakis, PA;MacÃas, D;Bargiela, DM;Pietsch, S;Gralla, M;Evans, CE;Kittipassorn, T;Chey, YCJ;Branco, CM;Rundqvist, H;Peet, DJ;Johnson, RS;
2018
29617647
April 3rd, 2018
United States
Physiological Laboratory, Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3EG, UK
Studies of Breast Cancer Chemoprevention in Human High-risk Primary Cells and Genetically Engineered Mouse Models
Thesis
Alothman, SJ;
2018
N/A
N/A
Abnormal Sleep Architecture and Hippocampal Circuit Dysfunction in a Mouse Model of Fragile X Syndrome
Neuroscience
Boone, CE;Davoudi, H;Harrold, JB;Foster, DJ;
2018
29775702
May 21st, 2018
United States
Medical Scientist Training Program, Johns Hopkins University School of Medicine, Baltimore, MD, United States; Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, United States
CSF1R+ Macrophages Sustain Pancreatic Tumor Growth through T Cell Suppression and Maintenance of Key Gene Programs that Define the Squamous Subtype
Cell Reports
Candido, JB;Morton, JP;Bailey, P;Campbell, AD;Karim, SA;Jamieson, T;Lapienyte, L;Gopinathan, A;Clark, W;McGhee, EJ;Wang, J;Escorcio-Correia, M;Zollinger, R;Roshani, R;Drew, L;Rishi, L;Arkell, R;Evans, TRJ;Nixon, C;Jodrell, DI;Wilkinson, RW;Biankin, AV;Barry, ST;Balkwill, FR;Sansom, OJ;
2018
29719257
May 1st, 2018
United Kingdom
Barts Cancer Institute, Queen Mary University of London, London EC1M 6BQ, UK
Role of Enteric Glial Activation in Gastrointestinal Physiology and Inflammation
Thesis
Delvalle-Dorta, NM;
2018
N/A
N/A
Global Untargeted Serum Metabolomic Analyses Nominate Metabolic Pathways Responsive to Loss of Expression of the Orphan Metallo β-Lactamase, Mblac1
Molecular Omics
Gibson, C;Codreanu, S;Schrimpe-Rutledge, A;Retzlaff, C;Wright, J;Mortlock, D;Sherrod, S;McLean, J;Blakely, R;
2018
May 28th, 2018
United States
Department of Biomedical Science, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, USA
MiR-142-3p is downregulated in aggressive p53 mutant mouse models of pancreatic ductal adenocarcinoma by hypermethylation of its locus
Cell Death and Disease
Godfrey, JD;Morton, JP;Wilczynska, A;Sansom, OJ;Bushell, MD;
2018
29844410
May 29th, 2018
United States
Medical Research Council Toxicology Unit, Lancaster Rd, Leicester, LE1 7HB, UK
Chemogenetic Enhancement of Axon Regeneration Following Peripheral Nerve Injury in the SLICK-A Mouse
Brain Sciences
Jaiswal, PB;Mistretta, OC;Ward, PJ;English, AW;
2018
29786639
May 22nd, 2018
United States
Department of Cell Biology, Emory University School of Medicine, Atlanta, GA 30322, USA
Identification of Correlative Shifts in Indices of Brain Cholesterol Metabolism in the C57BL6/Mecp2tm1.1Bird Mouse, a Model for Rett Syndrome
Lipids
Lütjohann, D;Lopez, AM;Chuang, JC;Kerksiek, A;Turley, SD;
2018
29770459
April 1st, 2018
Germany
Institute for Clinical Chemistry and Clinical Pharmacology, University Clinics of Bonn, Sigmund-Freud-Str. 25, 53127 Bonn, Germany
Spontaneous Hair Cell Regeneration Is Prevented by Increased Notch Signaling in Supporting Cells
Frontiers in Cellular Neuroscience
McGovern, MM;Zhou, L;Randle, MR;Cox, BC;
2018
29780306
May 4th, 2018
United States
Department of Pharmacology, School of Medicine, Southern Illinois University, Springfield, IL, United States
Membrane Mucin Muc4 promotes blood cell association with tumor cells and mediates efficient metastasis in a mouse model of breast cancer
Oncogene
Rowson-Hodel, AR;Wald, JH;Hatakeyama, J;O'Neal, WK;Stonebraker, JR;VanderVorst, K;Saldana, MJ;Borowsky, AD;Sweeney, C;Carraway, KL;
2018
28892049
January 11th, 2018
United States
Department of Biochemistry and Molecular Medicine, and UC Davis Comprehensive Cancer Center, University of California, Davis, School of Medicine, Sacramento, CA, USA
Separate functional properties of NMDARs regulate distinct aspects of spatial cognition
Learning & Memory
Sanders, EM;Nyarko-Odoom, AO;Zhao, K;Nguyen, M;Liao, HH;Keith, M;Pyon, J;Kozma, A;Sanyal, M;McHail, DG;Dumas, TC;
2018
29764972
June 1st, 2018
United States
Krasnow Institute for Advanced Study, George Mason University, Fairfax, Virginia 22030, USA
RNaseT2 knockout rats exhibit hippocampal neuropathology and deficits in memory
Disease Models and Mechanisms
Sinkevicius, KW;Morrison, TR;Kulkarni, P;Cagliostro, MKC;Iriah, S;Malmberg, S;Sabrick, J;Honeycutt, JA;Askew, KL;Trivedi, M;Ferris, CF;
2018
29752287
May 10th, 2018
United States
Preclinical Pharmacology, Alexion Pharmaceuticals, Lexington, MA 02421, USA
Brown adipose tissue plays a central role in systemic inflammation-induced sleep responses
PLOS ONE
Szentirmai, É;Kapás, L;
2018
29746591
May 10th, 2018
United States
Elson S. Floyd College of Medicine, Department of Biomedical Sciences, Washington State University, Spokane, Washington, United States of America
Cell-Type-Specific Role of ΔFosB in Nucleus Accumbens In Modulating Intermale Aggression
The Journal of Neuroscience
Aleyasin, H;Flanigan, ME;Golden, SA;Takahashi, A;Menard, C;Pfau, ML;Multer, J;Pina, J;McCabe, KA;Bhatti, N;Hodes, GE;Heshmati, M;Neve, RL;Nestler, EJ;Heller, EA;Russo, SJ;
2018
29891732
June 27th, 2018
United States
Fishberg Department of Neuroscience, Friedman Brain Institute, and Center for Affective Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York 10029
A Combination of Ontogeny and CNS Environment Establishes Microglial Identity
Neuron
Bennett, FC;Bennett, ML;Yaqoob, F;Mulinyawe, SB;Grant, GA;Hayden Gephart, M;Plowey, ED;Barres, BA;
2018
29861285
June 27th, 2018
United States
Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
TectaY1870C/+ mice with alterations in the structure and porosity of the tectorial membrane display large numbers of spontaneous emissions
AIP Conference Proceedings
Cheatham, M;Ahmad, A;Dallos, P;Richardson, G;
2018
June 1st, 2018
United States
Department of Communication Sciences and Disorders, The Hugh Knowles Center, 2240 Campus Drive, Northwestern University, Evanston IL 60208, USA
The Biochemical Effects of Tau and Zinc in A Tau Mouse Model
Thesis
Craven, KM;
2018
N/A
N/A
Zinc Exacerbates Tau Pathology in a Tau Mouse Model
Journal of Alzheimers Disease
Craven, KM;Kochen, WR;Hernandez, CM;Flinn, JM;
2018
29914030
June 20th, 2018
United States
George Mason University, Fairfax, VA, USA
Effects of living at moderate altitude on pulmonary vascular function and exercise capacity in mice with sickle cell anemia
The Journal of Physiology
Ferguson, SK;Redinius, K;Yalamanoglu, A;Harral, JW;Hyen Baek, J;Pak, D;Loomis, Z;Hassel, D;Eigenberger, P;Grayck, E;Nuss, R;Hassell, K;Stenmark, KR;Buehler, PW;Irwin, DC;
2018
29931797
June 21st, 2018
United States
Cardiovascular and Pulmonary Research Laboratory, Department of Medicine, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, 80045, USA
Hydroxyurea embryotoxicity is enhanced in P53-deficient mice
Reproductive Toxicology
Husseini, NE;Hales, BF;
2018
29940331
June 22nd, 2018
Canada
Department of Pharmacology and Therapeutics, McGill University, Montreal, Quebec, Canada
Functional cross-talk between PTEN and PDK1 in normal haematopoiesis and leukaemia development
Thesis
Lekgetho, H;
2018
N/A
N/A
Investigating the role of thiosulfate sulfurtransferase in adipose tissue dysfunction in obesity
Thesis
Mc Fadden, CE;
2018
N/A
N/A
A novel sialylation site on Neisseria gonorrhoeae lipooligosaccharide links heptose II lactose expression with pathogenicity
Infection and Immunity
Ram, S;Gulati, S;Lewis, LA;Chakraborti, S;Zheng, B;DeOliveira, RB;Reed, GW;Cox, AD;Li, J;St Michael, F;Stupak, J;Su, XH;Saha, S;Landig, CS;Varki, A;Rice, PA;
2018
29844237
May 29th, 2018
United States
Division of Infectious Diseases and Immunology and Preventive and Behavioral Medicine, University of Massachusetts Medical School, Worcester MA 01605, USA
Impairing hepatocyte regeneration to determine the regenerative capacity of the biliary epithelium
Thesis
Raven, AP;
2018
N/A
N/A
Iron Chelation with Transdermal Deferoxamine Accelerates Healing of Murine Sickle Cell Ulcers
Advances in Wound Care
Rodrigues, M;Bonham, C;Minniti, C;Gupta, K;Longaker, M;Gurtner, G;
2018
June 18th, 2018
United States
Department of Surgery, Stanford University School of Medicine, Stanford, California
POT1a depletion in the developing brain leads to p53-dependent neuronal cell death and ataxia.
bioRxiv
She, R;Clapp, C;Lazzerini Denchi, E;
2018
May 31st, 2018
United States
Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA
TSPO-PET Imaging Using [18F]PBR06 is a Potential Translatable Biomarker for Treatment Response in Huntington's Disease: Preclinical Evidence with the p75NTR Ligand LM11A-31
Human Molecular Genetics
Simmons, DA;James, ML;Belichenko, NP;Semaan, S;Condon, C;Kuan, J;Shuhendler, AJ;Miao, Z;Chin, FT;Longo, FM;
2018
29860333
May 30th, 2018
United States
Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305
Characterization of Adult Vestibular Organs in 11 CreER Mouse Lines
Journal of the Association for Research in Otolaryngology (JARO)
Stone, JS;Wisner, SR;Bucks, SA;Mellado Lagarde, MM;Cox, BC;
2018
29869046
June 4th, 2018
United States
Department of Otolaryngology-Head and Neck Surgery, Virginia Merrill Bloedel Hearing Research Center, University of Washington, Seattle, WA, USA
Targeted deletion of c-Met in thymic epithelial cells leads to an autoimmune phenotype
Immunology and Cell Biology
Su, M;Hu, R;Song, Y;Liu, Y;Lai, L;
2018
29363160
February 1st, 2018
United States
Department of Allied Health Sciences, University of Connecticut, Storrs, CT, USA
Temporal changes in macrophage phenotype after peripheral nerve injury
Journal of Neuroinflammation
Tomlinson, JE;Žygelytė, E;Grenier, JK;Edwards, MG;Cheetham, J;
2018
29907154
June 15th, 2018
United States
Cornell University College of Veterinary Medicine, Ithaca, NY, USA
Differential electrophysiological properties of D1 and D2 spiny projection neurons in the mouse nucleus accumbens core
Physiological Reports
Al-Muhtasib, N;Forcelli, PA;Vicini, S;
2018
29962016
July 1st, 2018
United States
Department of Pharmacology & Physiology, Georgetown University Medical Center, Washington, District of Columbia
Constitutive and Conditional Deletion of Type 1 Dopamine Receptor (Drd1) to Study Food Anticipatory Activity
Thesis
Assali, D;
2018
n/a
n/a
Alterations of functional circuitry in aging brain and the impact of mutated APP expression
Neurobiology of Aging
Bearer, EL;Manifold-Wheeler, BC;Medina, CS;Gonzales, AG;Chaves, FL;Jacobs, RE;
2018
30055413
June 28th, 2018
Mexico
University of New Mexico Health Sciences Center, Albuquerque, NM, USA; Division of Biology, California Institute of Technology, Pasadena, CA, USA
Triheteromeric GluN1/GluN2A/GluN2C NMDARs with Unique Single-Channel Properties Are the Dominant Receptor Population in Cerebellar Granule Cells
Neuron
Bhattacharya, S;Khatri, A;Swanger, SA;DiRaddo, JO;Yi, F;Hansen, KB;Yuan, H;Traynelis, SF;
2018
30056832
July 25th, 2018
United States
Department of Pharmacology, Emory University School of Medicine, Atlanta, GA 30322, USA
Synaptic vesicle recycling in preclinical models of intellectual disability, autism spectrum disorder and epilepsy
Thesis
Bonnycastle, K;
2018
n/a
n/a
Tropomyosin 3.5 protects F-actin networks required for tissue biomechanical properties
bioRxiv
Cheng, C;Nowak, R;Amadeo, M;Biswas, S;Lo, W;Fowler, V;
2018
June 28th, 2018
United States
Department of Molecular Medicine, The Scripps Research Institute, La Jolla, CA
Persistent Infiltration and Impaired Response of Peripherally-Derived Monocytes after Traumatic Brain Injury in the Aged Brain
International Journal of Molecular Sciences
Chou, A;Krukowski, K;Morganti, JM;Riparip, LK;Rosi, S;
2018
29848996
May 30th, 2018
United States
Brain and Spinal Injury Center, University of California, San Francisco, CA 94143, USA
Effects of 5-HT1A Receptor Agonism on Repetitive Grooming and Learning Behavior in Shank3B Mice
Thesis
Dunn, JT;
2018
n/a
n/a
Contractile functions of Piezo1 channels in murine arteries
Thesis
Endesh, NEM;
2018
United Kingdom
n/a
GAL3 receptor knockout mice exhibit an alcohol-preferring phenotype
Addiction Biology
Genders, SG;Scheller, KJ;Jaehne, EJ;Turner, BJ;Lawrence, AJ;Brunner, SM;Kofler, B;van den Buuse, M;Djouma, E;
2018
29984872
July 9th, 2018
Australia
School of Life Sciences, Department of Physiology, Anatomy and Microbiology, La Trobe University, Australia
Suppression of Harmaline Tremor by Activation of an Extrasynaptic GABAA Receptor: Implications for Essential Tremor
Tremor and Other Hyperkinetic Movements
Handforth, A;Kadam, PA;Kosoyan, HP;
2018
United States
Neurology Service, Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA, USA
Disruption of the Zdhhc9 intellectual disability gene leads to behavioural abnormalities in a mouse model
Experimental Neurology
Kouskou, M;Thomson, DM;Brett, RR;Wheeler, L;Tate, RJ;Pratt, JA;Chamberlain, LH;
2018
29944857
June 23rd, 2018
United Kingdom
Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, United Kingdom
Citrullinated histone 3 causes endothelial barrier dysfunction
Biochemical and Biophysical Research Communications
Meegan, JE;Yang, X;Beard, RS;Jannaway, M;Chatterjee, V;Taylor-Clark, TE;Yuan, SY;
2018
30029877
July 17th, 2018
United States
Department of Molecular Pharmacology & Physiology, University of South Florida Morsani College of Medicine, Tampa, FL, USA
53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in
Nature
Mirman, Z;Lottersberger, F;Takai, H;Kibe, T;Gong, Y;Takai, K;Bianchi, A;Zimmermann, M;Durocher, D;de Lange, T;
2018
30022158
August 1st, 2018
United States
Laboratory for Cell Biology and Genetics, Rockefeller University, New York, NY, USA
Loss of maternal EED results in postnatal overgrowth
Clinical Epigenetics
Prokopuk, L;Stringer, JM;White, CR;Vossen, RHAM;White, SJ;Cohen, ASA;Gibson, WT;Western, PS;
2018
30005706
July 13th, 2018
Australia
Centre for Reproductive Health, Hudson Institute of Medical Research and Department of Molecular and Translational Science, Monash University, Clayton, Victoria, 3168, Australia
The role of Runx1 in genetic models of breast cancer
Thesis
Riggio, AI;
2017
n/a
n/a
This is to certify that the work contained within has been composed by me and is entirely my own work. No part of this thesis has been submitted for any other
Thesis
Sime, NEL;
2018
n/a
n/a
Pathway specific drive of cerebellar Golgi cells reveals integrative rules of cortical inhibition
bioRxiv
Tabuchi, S;Gilmer, J;Purba, K;Person, A;
2018
June 27th, 2018
n/a
Department of Physiology & Biophysics
Depletion of haptoglobin and hemopexin promote hemoglobin-mediated lipoprotein oxidation in sickle cell disease
American Journal of Physiology
Yalamanoglu, A;Deuel, JW;Hunt, RC;Baek, JH;Hassell, K;Redinius, K;Irwin, DC;Schär, DJ;Buehler, PW;
2018
30047285
July 26th, 2018
United States
United States
Inhibiting autophagy reduces retinal degeneration caused by protein misfolding
Autophagy
Yao, J;Qiu, Y;Frontera, E;Jia, L;Khan, NW;Klionsky, DJ;Ferguson, TA;Thompson, DA;Zacks, DN;
2018
29940785
July 13th, 2018
United States
a Department of Ophthalmology and Visual Sciences , University of Michigan , Ann Arbor , MI , USA
CTCF maintains regulatory homeostasis of cancer pathways
Genome Biology
Aitken, SJ;Ibarra-Soria, X;Kentepozidou, E;Flicek, P;Feig, C;Marioni, JC;Odom, DT;
2018
30086769
August 7th, 2018
United Kingdom
Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK
Astrocytes and neurons produce distinct types of polyglucosan bodies in Lafora disease
Glia
Augé, E;PelegrÃ, C;Manich, G;Cabezón, I;Guinovart, JJ;Duran, J;Vilaplana, J;
2018
30152044
August 26th, 2018
Spain
Secció de Fisiologia, Departament de BioquÃmica i Fisiologia, Universitat de Barcelona, Barcelona, Spain
MYBL2 supports DNA double strand break repair in haematopoietic stem cells
Cancer Research
Bayley, R;Blakemore, D;Cancian, L;Dumon, S;Volpe, G;Ward, C;Almaghrabi, R;Gujar, J;Reeve, N;Raghavan, M;Higgs, MR;Stewart, GS;Petermann, E;Garcia, P;
2018
30082276
August 6th, 2018
United Kingdom
Institute of Cancer and Genomic Sciences, University of Birmingham
An Examination of the Role of L-Glutamate and Inosine 5'-Monophosphate in Hedonic Taste-Guided Behavior by Mice Lacking the T1R1 + T1R3 Receptor
Chemical Senses
Blonde, GD;Spector, AC;
2017
28334294
June 1st, 2017
United States
Department of Psychology and Program in Neuroscience, Florida State University, Tallahassee, FL, USA
Communication Between Enteric Neurons, Glia, and Nociceptors Underlies the Effects of Tachykinins on Neuroinflammation
Cellular and Molecular Gastroenterology and Hepatology
Delvalle, NM;Dharshika, C;Morales-Soto, W;Fried, DE;Gaudette, L;Gulbransen, BD;
2018
30116771
May 29th, 2018
United States
Neuroscience Program, Michigan State University, East Lansing, Michigan
GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine
Oncogene
Ferro, R;Adamska, A;Lattanzio, R;Mavrommati, I;Edling, CE;Arifin, SA;Fyffe, CA;Sala, G;Sacchetto, L;Chiorino, G;De Laurenzi, V;Piantelli, M;Sansom, OJ;Maffucci, T;Falasca, M;
2018
30061636
July 30th, 2018
Australia
Queen Mary University of London, Barts and The London School of Medicine and Dentistry, Blizard Institute, Centre for Cell Biology and Cutaneous Research, 4 Newark Street, London, E1 2AT, UK
Intestine-specific expression of human chimeric intestinal alkaline phosphatase attenuates Western diet-induced barrier dysfunction and glucose intolerance
Physiological Reports
Ghosh, SS;He, H;Wang, J;Korzun, W;Yannie, PJ;Ghosh, S;
2018
30058275
July 1st, 2018
United States
Department of Internal Medicine, VCU Medical Center, Richmond, Virginia
Distinct Bone Marrow Sources of Pleiotrophin Control Hematopoietic Stem Cell Maintenance and Regeneration
Stem Cells
Himburg, HA;Termini, CM;Schlussel, L;Kan, J;Li, M;Zhao, L;Fang, T;Sasine, JP;Chang, VY;Chute, JP;
2018
30100167
July 30th, 2018
United States
Division of Hematology/Oncology, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
Mapping Transgene Insertion Sites Reveals Complex Interactions Between Mouse Transgenes And Neighboring Endogenous Genes
bioRxiv
Laboulaye, M;Duan, X;Qiao, M;Whitney, I;Sanes, J;
2018
August 10th, 2018
United States
Center for Brain Science and Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA, 02138
Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration
Cell Reports
Latremoliere, A;Cheng, L;DeLisle, M;Wu, C;Chew, S;Hutchinson, EB;Sheridan, A;Alexandre, C;Latremoliere, F;Sheu, SH;Golidy, S;Omura, T;Huebner, EA;Fan, Y;Whitman, MC;Nguyen, E;Hermawan, C;Pierpaoli, C;Tischfield, MA;Woolf, CJ;Engle, EC;
2018
30110642
August 14th, 2018
United States
Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA; Department of Neurobiology, Harvard Medical School, Boston, MA, USA
Exacerbation of dystrophic cardiomyopathy by phospholamban deficiency-mediated chronically increased cardiac Ca2+ cycling in vivo
American Journal of Physiology
Law, ML;Prins, KW;Olander, ME;Metzger, JM;
2018
30118340
August 17th, 2018
United States
Department of Integrative Biology and Physiology, University of Minnesota
Ndr kinases regulate retinal interneuron proliferation and homeostasis
Scientific Reports
Léger, H;Santana, E;Leu, NA;Smith, ET;Beltran, WA;Aguirre, GD;Luca, FC;
2018
30135513
August 22nd, 2018
United States
Department of Biomedical Sciences, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA, United States
One-step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock-in mice
The EMBO Journal
Lin, YC;Pecetta, S;Steichen, JM;Kratochvil, S;Melzi, E;Arnold, J;Dougan, SK;Wu, L;Kirsch, KH;Nair, U;Schief, WR;Batista, FD;
2018
30087111
August 7th, 2018
United States
Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA
Apigenin Inhibits UVB-Induced Skin Carcinogenesis: The Role of Thrombospondin-1 as an Anti-Inflammatory Factor
Neoplasia
Mirzoeva, S;Tong, X;Bridgeman, BB;Plebanek, MP;Volpert, OV;
2018
30118999
August 14th, 2018
United States
Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611
Loss of MST/Hippo signaling in a genetically engineered mouse model of fusion-positive rhabdomyosarcoma accelerates tumorigenesis
Cancer Research
Oristian, KM;Crose, LES;Kuprasertkul, N;Bentley, RC;Lin, YT;Williams, N;Kirsch, DG;Linardic, CM;
2018
30093562
August 9th, 2018
United States
Division Pediatric Hematology-Oncology, Duke University Medical Center
A Dominant Role for the Beta 4 Nicotinic Receptor Subunit in Nicotinic Modulation of Glomerular Microcircuits in the Mouse Olfactory Bulb
Journal of Neurophysiology
Spindle, MS;Parsa, PV;Bowles, SG;D'Souza, RD;Vijayaraghavan, S;
2018
30089021
August 8th, 2018
United States
Physiology and Biophysics, University of Colorado, School of Medicine
PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner
Nature Communications
Stark, AK;Chandra, A;Chakraborty, K;Alam, R;Carbonaro, V;Clark, J;Sriskantharajah, S;Bradley, G;Richter, AG;Banham-Hall, E;Clatworthy, MR;Nejentsev, S;Hamblin, JN;Hessel, EM;Condliffe, AM;Okkenhaug, K;
2018
30093657
August 9th, 2018
United Kingdom
Laboratory of Lymphocyte Signalling and Development, Babraham Institute, Cambridge, CB21 3AT, UK
Prestin Contributes to Membrane Compartmentalization and Is Required for Normal Innervation of Outer Hair Cells
Frontiers in Cellular Neuroscience
Takahashi, S;Sun, W;Zhou, Y;Homma, K;Kachar, B;Cheatham, MA;Zheng, J;
2018
30079013
July 20th, 2018
United States
Department of Otolaryngology - Head and Neck Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States
Fine-Tuning Mybl2 Is Required for Proper Mesenchymal-to-Epithelial Transition during Somatic Reprogramming
Cell Reports
Ward, C;Volpe, G;Cauchy, P;Ptasinska, A;Almaghrabi, R;Blakemore, D;Nafria, M;Kestner, D;Frampton, J;Murphy, G;Buganim, Y;Kaji, K;GarcÃa, P;
2018
30089261
August 7th, 2018
United Kingdom
Institute of Cancer and Genomic Science, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
Deficiency of the Endocytic Protein Hip1 Leads to Decreased Gdpd3 expression, Low Phosphocholine, and Kypholordosis
bioRxiv
wijayatunge, R;Holmstrom, S;foley, s;mgbemena, v;bhargava, v;perez, g;mccrum, k;ross, T;
2018
August 2nd, 2018
United States
From the Department of Internal Medicine, University of Texas Southwestern Medical 16 Center, Dallas, TX
Knock-in rats expressing Cre and Flp recombinases at the Parvalbumin locus.
bioRxiv
Yu, J;Pettibone, J;Guo, C;Zhang, S;Saunders, T;Hughes, E;Filipiak, W;Zeidler, M;Bender, K;Hopf, F;Smyth, C;Kharazia, V;Kiseleva, A;Davidson, T;Frank, L;Berke, J;
2018
August 7th, 2018
United States
Howard Hughes Medical Institute, University of California San Francisco
Whole genomes redefine the mutational landscape of pancreatic cancer
Nature
Waddell, N;Pajic, M;Patch, AM;Chang, DK;Kassahn, KS;Bailey, P;Johns, AL;Miller, D;Nones, K;Quek, K;Quinn, MC;Robertson, AJ;Fadlullah, MZ;Bruxner, TJ;Christ, AN;Harliwong, I;Idrisoglu, S;Manning, S;Nourse, C;Nourbakhsh, E;Wani, S;Wilson, PJ;Markham, E;Cloonan, N;Anderson, MJ;Fink, JL;Holmes, O;Kazakoff, SH;Leonard, C;Newell, F;Poudel, B;Song, S;Taylor, D;Waddell, N;Wood, S;Xu, Q;Wu, J;Pinese, M;Cowley, MJ;Lee, HC;Jones, MD;Nagrial, AM;Humphris, J;Chantrill, LA;Chin, V;Steinmann, AM;Mawson, A;Humphrey, ES;Colvin, EK;Chou, A;Scarlett, CJ;Pinho, AV;Giry-Laterriere, M;Rooman, I;Samra, JS;Kench, JG;Pettitt, JA;Merrett, ND;Toon, C;Epari, K;Nguyen, NQ;Barbour, A;Zeps, N;Jamieson, NB;Graham, JS;Niclou, SP;Bjerkvig, R;GrÌ_tzmann, R;Aust, D;Hruban, RH;Maitra, A;Iacobuzio-Donahue, CA;Wolfgang, CL;Morgan, RA;Lawlor, RT;Corbo, V;Bassi, C;Falconi, M;Zamboni, G;Tortora, G;Tempero, MA;, ;Gill, AJ;Eshleman, JR;Pilarsky, C;Scarpa, A;Musgrove, EA;Pearson, JV;Biankin, AV;Grimmond, SM;
2015
25719666
February 26th, 2015
United Kingdom
1] Queensland Centre for Medical Genomics, Institute for Molecular Bioscience, The University of Queensland, St Lucia, Brisbane, Queensland 4072, Australia [2] Wolfson Wohl Cancer Research Centre, Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Switchback Road, Bearsden, Glasgow G61 1BD, UK
Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model
Diabetes
Gier, B;Matveyenko, AV;Kirakossian, D;Dawson, D;Dry, SM;Butler, PC;
2012
22266668
May 1st, 2012
United States
Larry L. Hillblom Islet Research Center, University of California Los Angeles (UCLA), David Geffen School of Medicine, Los Angeles, California, USA
Lhx1 controls terminal differentiation and circadian function of the suprachiasmatic nucleus
Cell Reports
Bedont, JL;LeGates, TA;Slat, EA;Byerly, MS;Wang, H;Hu, J;Rupp, AC;Qian, J;Wong, GW;Herzog, ED;Hattar, S;Blackshaw, S;
2014
24767996
May 1st, 2014
United States
Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Physiology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Center for High-Throughput Biology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA; Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
Sialylation regulates brain structure and function
FASEB Journal
Yoo, SW;Motari, MG;Susuki, K;Prendergast, J;Mountney, A;Hurtado, A;Schnaar, RL;
2015
25846372
July 1st, 2015
United States
*Department of Pharmacology and Molecular Sciences, Department of Neurology, and Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA; Department of Neuroscience, Baylor College of Medicine, Houston, Texas, USA; Brain Trauma Neuroprotection and Neurorestoration Branch, Center for Military Psychiatry and Neuroscience, Walter Reed Army Institute of Research, Silver Spring, Maryland, USA; and International Center for Spinal Cord Injury, Hugo W. Moser Research Institute, Kennedy Krieger, Baltimore, Maryland, USA
Trp63 is regulated by STAT5 in mammary tissue and subject to differentiation in cancer
Endocrine Related Cancer
Assefnia, S;Kang, K;Groeneveld, S;Yamaji, D;Dabydeen, S;Alamri, A;Liu, X;Hennighausen, L;Furth, PA;
2014
24692510
June 1st, 2014
United States
Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, 3970 Reservoir Road NW, Research Building, Room 520A, Washington, District of Columbia 20057, USA Laboratory of Genetics and Physiology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, 8 Center Drive, Bethesda, Maryland 20892-0822, USA Department of Microbiology, Dankook University, Cheonan 330-714, Republic of Korea Department Pharmazie, Ludwig-Maximilians-UniversitÌ_t MÌ_nchen, MÌ_nchen, Germany College of Medical Sciences, King Khalid University, Abha, Saudi Arabia Departments of Pathology Medicine, Lombardi Comprehensive Cancer Center, Georgetown University, 3970 Reservoir Road NW, Research Building, Room 520A, Washington, District of Columbia 20057 USA
Beneficial Effect of the Nitric Oxide Donor Compound 3-(1,3-Dioxoisoindolin-2-yl)Benzyl Nitrate on Dysregulated Phosphodiesterase 5, NADPH Oxidase, and Nitrosative Stress in the Sickle Cell Mouse Penis: Implication for Priapism Treatment
Journal of Pharmacology and Expreimental Therapeutics
Silva, FH;Karakus, S;Musicki, B;Matsui, H;Bivalacqua, TJ;Dos Santos, JL;Costa, FF;Burnett, AL;
2016
27540002
November 1st, 2016
United States
James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins School of Medicine, Baltimore, Maryland (F.H.S., S.K., B.M., H.M., T.J.B., A.L.B.); Hematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil (F.H.S., F.F.C.); and LaboratÃŒ_rio de Pesquisa e Desenvolvimento de FÃŒÃrmacos, Faculdade de CiÌ»ncias FarmacÌ»uticas, Universidade Estadual Paulista, Araraquara, SP, Brazil (J.L.S.)
Sex-specific regulation of weight and puberty by the Lin28/let-7 axis
Journal of Endocrinology
Corre, C;Shinoda, G;Zhu, H;Cousminer, DL;Crossman, C;Bellissimo, C;Goldenberg, A;Daley, GQ;Palmert, MR;
2016
26698568
March 1st, 2016
Canada
Division of EndocrinologyThe Hospital for Sick Children, 555 University Avenue, Toronto ON, M5G 1X8, CanadaDivision of Hematology/OncologyBoston Children's Hospital, Boston, Massachusetts, USADepartments of Pediatrics and Internal MedicineChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, Texas, USAInstitute for Molecular MedicineFinland (FIMM), University of Helsinki, Helsinki, FinlandGenetics and Genome Biology ProgramThe Hospital for Sick Children, Toronto, Ontario, CanadaDepartment of Computer ScienceUniversity of Toronto, Toronto, Ontario, CanadaDepartments of Paediatrics and PhysiologyThe University of Toronto, Toronto, Ontario, Canada Division of EndocrinologyThe Hospital for Sick Children, 555 University Avenue, Toronto ON, M5G 1X8, CanadaDivision of Hematology/OncologyBoston Children's Hospital, Boston, Massachusetts, USADepartments of Pediatrics and Internal MedicineChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, Texas, USAInstitute for Molecular MedicineFinland (FIMM), University of Helsinki, Helsinki, FinlandGenetics and Genome Biology ProgramThe Hospital for Sick Children, Toronto, Ontario, CanadaDepartment of Computer ScienceUniversity of Toronto, Toronto, Ontario, CanadaDepartments of Paediatrics and PhysiologyThe University of Toronto, Toronto, Ontario, Canada
Isoaspartyl formation in creatine kinase B is associated with loss of enzymatic activity; implications for the linkage of isoaspartate accumulation and neurological dysfunction in the PIMT knockout mouse
PLOS ONE
Dimitrijevic, A;Qin, Z;Aswad, DW;
2014
24955845
June 24th, 2014
United States
Department of Molecular Biology & Biochemistry, University of California Irvine, Irvine, California, United States of America
Corrigendum to Enkephalin levels and the number of neuropeptide Y-containing interneurons in the hippocampus are decreased in female cannabinoid-receptor 1 knock-out mice [Neurosci. Lett. 620 (2016) 97-103]
Neuroscience Letters
Rogers, SA;Van Kempen, TA;Pickel, VM;Milner, TA;
2016
27665046
October 28th, 2016
United States
Feil Family Brain and Mind Research Institute, Weill Cornell Medicine, 407 East 61st Street, New York, NY 10065, United States
Investigating the Production of Auto-Antibodies at Different Stages of B Cell Development
Thesis
Larbi, AA;
2013
Kwame Nkrumah University of Science and Technology
Targeted lentiviral-mediated delivery of progranulin cDNA in a genetic model of amyotrophic lateral sclerosis
Thesis
Zwiegers, P;
2015
Hippocampal neural progenitor cells play a distinct role in fear memory retrieval in male and female CIE rats
Neuropharmacology
Fannon, M;Mysore, K;Williams, J;Quach, L;Purohit, D;Sibley, B;Sage-Sepulveda, J;Kharidia, K;Morales Silva, R;Terranova, M;Somkuwar, S;Staples, M;Mandyam, C;
2018
September 1st, 2018
United States
Veterans Medical Research Foundation, VA San Diego Healthcare System, San Diego, CA, USA
Metabolic and vascular effects of thiosulfate sulfurtransferase deletion
Thesis
Gibbins, MTG;
2018
Ketogenic diet regulates the antioxidant catalase via the transcription factor PPAR?2
Epilepsy Res.
Knowles, S;Budney, S;Deodhar, M;Matthews, SA;Simeone, KA;Simeone, TA;
2018
30261354
September 21st, 2018
United States
Creighton University, School of Medicine, Department of Pharmacology, Omaha, NE, 68174, USA
Examining the Role of Cone-expressed RPE65 in Mouse Cone Function
Sci Rep
Kolesnikov, AV;Tang, PH;Kefalov, VJ;
2018
30242264
September 21st, 2018
United States
Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, Saint Louis, MO, 63110, USA
Increased tau phosphorylation follows impeded dopamine clearance in a P301L and novel P301L/COMT-deleted (DM) tau mouse model
J. Neurochem.
Koppel, J;Jimenez, H;Adrien, L;Chang, E;Malhotra, AK;Davies, P;
2018
30238463
September 20th, 2018
The Litwin-Zucker Research Center for the Study of Alzheimer's Disease, The Feinstein Institute for Medical Research, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell
Inhibition of Atypical Protein Kinase C Reduces Inflammation-Induced Retinal Vascular Permeability
Am. J. Pathol.
Lin, CM;Titchenell, PM;Keil, JM;Garcia-Ocaña, A;Bolinger, MT;Abcouwer, SF;Antonetti, DA;
2018
30220554
October 1st, 2018
United States
Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan
Cre-dependent optogenetic transgenic mice without early age-related hearing loss
bioRxiv
Lyngholm, D;Sakata, S;
2018
September 13th, 2018
United Kingdom
Strathclyde Institute of Pharmacy and Biomedical Sciences University of Strathclyde 161 Cathedral Street, Glasgow G4 0RE, UK
Precision medicine approach: Empagliflozin for diabetic cardiomyopathy in mice with aldehyde dehydrogenase (ALDH) 2?2 mutation, a specific genetic mutation in millions of East Asians
Eur. J. Pharmacol.
Pan, G;Deshpande, M;Pang, H;Palaniyandi, SS;
2018
30240795
September 18th, 2018
United States
Division of Hypertension and Vascular Research, Department of Internal Medicine, Henry Ford Health System, Detroit, MI 48202
The EGF-LIKE domain of thrombospondin-4 is a key determinant in the development of pain states due to increased excitatory synaptogenesis
J. Biol. Chem.
Park, JF;Yu, YP;Gong, N;Trinh, VN;Luo, ZD;
2018
30194282
September 7th, 2018
United States
University of California Irvine, United States
GIRK currents in VTA dopamine neurons control the sensitivity of mice to cocaine-induced locomotor sensitization
Proc. Natl. Acad. Sci. U.S.A.
Rifkin, RA;Huyghe, D;Li, X;Parakala, M;Aisenberg, E;Moss, SJ;Slesinger, PA;
2018
30228121
September 18th, 2018
United States
Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY 10029
Mouse Models of Pain in Sickle Cell Disease
Curr Protoc Neurosci
Sagi, V;Song-Naba, WL;Benson, BA;Joshi, SS;Gupta, K;
2018
30265442
September 28th, 2018
United States
Vascular Biology Center, Division of Hematology, Oncology and Transplantation, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota
Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance
BMC Biol.
Stringer, JM;Forster, SC;Qu, Z;Prokopuk, L;O'Bryan, MK;Gardner, DK;White, SJ;Adelson, D;Western, PS;
2018
30236109
September 20th, 2018
Australia
Centre for Reproductive Health, Hudson Institute of Medical Research, Clayton, Victoria, 3168, Australia
Sex differences in vocal communication of freely interacting adult mice depend upon behavioral context
PLOS ONE
Warren, MR;Spurrier, MS;Roth, ED;Neunuebel, JP;
2018
30240434
September 21st, 2018
United States
Department of Psychological and Brain Sciences, University of Delaware, Newark, Delaware, United States of America
The susceptibility of cochlear outer hair cells to cyclodextrin is not related to their electromotile activity
Acta Neuropathol Commun
Zhou, Y;Takahashi, S;Homma, K;Duan, C;Zheng, J;Cheatham, MA;Zheng, J;
2018
30249300
September 24th, 2018
United States
Department of Communication Sciences and Disorders, Northwestern University, Evanston, IL, 60208, USA
Astrocyte-Secreted Chordin-like 1 Drives Synapse Maturation and Limits Plasticity by Increasing Synaptic GluA2 AMPA Receptors
Neuron
Blanco-Suarez, E;Liu, TF;Kopelevich, A;Allen, NJ;
2018
30344043
October 12th, 2018
United States
The Salk Institute for Biological Studies, Molecular Neurobiology Laboratory, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
Impaired innate immune signaling due to combined Toll-like receptor 2 and 4 deficiency affects both periodontitis and atherosclerosis in response to polybacterial infection
Pathog Dis
Chukkapalli, SS;Ambadapadi, S;Varkoly, K;Jiron, J;Aguirre, JI;Bhattacharyya, I;Morel, LM;Lucas, AR;Lakshmyya, K;
2018
30351354
October 23rd, 2018
United States
Department of Periodontology, College of Dentistry, University of Florida, Gainesville, FL 32610, USA
Estudio de variantes estructurales de ApoA-I y ApoJ recombinantes como aproximación terapéutica en el contexto de la ß-amiloidosis cerebral
Thesis
Fernandez de Retana Alda, S;
2018
Sex-Dependent Effects of Environmental Enrichment on Spatial Memory and Brain-Derived Neurotrophic Factor (BDNF) Signaling in a Developmental "Two-Hit" Mouse Model Combining BDNF Haploinsufficiency and Chronic Glucocorticoid Stimulation
Front Behav Neurosci
Grech, AM;Ratnayake, U;Hannan, AJ;van den Buuse, M;Hill, RA;
2018
30356704
October 9th, 2018
Australia
Department of Psychiatry, School of Clinical Sciences, Monash Medical Centre, Monash University, Clayton, VIC, Australia
Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth
Breast Cancer Res.
Mao, SPH;Park, M;Cabrera, RM;Christin, JR;Karagiannis, GS;Oktay, MH;Zaiss, DMW;Abrams, SI;Guo, W;Condeelis, JS;Kenny, PA;Segall, JE;
2018
30367629
October 26th, 2018
United States
Department of Anatomy and Structural Biology, Albert Einstein College of Medicine, 1301 Morris Park Avenue, Bronx, NY, 10461, USA
Injury promotes sarcoma development in a genetically and temporally restricted manner
JCI Insight
Van Mater, D;Xu, E;Reddy, A;Añó, L;Sachdeva, M;Huang, W;Williams, N;Ma, Y;Love, C;Happ, L;Dave, S;Kirsch, DG;
2018
30333301
October 18th, 2018
Canada
Department of Pediatrics, Division of Hematology-Oncology
Investigating the Ca2+-dependent and Ca2+-independent mechanisms for mammalian cone light adaptation
Sci Rep
Vinberg, F;Kefalov, VJ;
2018
30367097
October 26th, 2018
United States
Ophthalmology and Visual Sciences, Washington University School of Medicine, St. Louis, Missouri, USA
Genetic and behavioural requirements for structural brain plasticity
bioRxiv
Vousden, D;Friesen, A;Wen, X;Qiu, L;O'Toole, N;Darwin, B;Spencer Noakes, L;Allemang-Grand, R;Diorio, J;Frankland, P;Josselyn, S;Nieman, B;Meaney, M;Zhang, T;Lerch, J;
2018
October 3rd, 2018
Canada
Mouse Imaging Centre, The Hospital for Sick Children, 25 Orde Street, Toronto, ON, M5T 3H7, Canada
Fisetin is a senotherapeutic that extends health and lifespan
EBioMedicine
Yousefzadeh, MJ;Zhu, Y;McGowan, SJ;Angelini, L;Fuhrmann-Stroissnigg, H;Xu, M;Ling, YY;Melos, KI;Pirtskhalava, T;Inman, CL;McGuckian, C;Wade, EA;Kato, JI;Grassi, D;Wentworth, M;Burd, CE;Arriaga, EA;Ladiges, WL;Tchkonia, T;Kirkland, JL;Robbins, PD;Niedernhofer, LJ;
2018
30279143
October 1st, 2018
United States
Department of Molecular Medicine and the Center on Aging, The Scripps Research Institute, 130 Scripps Way, Jupiter, FL 33458, United States
Early functional connectivity deficits and progressive microstructural alterations in the TgF344-AD rat model of Alzheimer's Disease: A longitudinal MRI study
Neurobiol. Dis.
Anckaerts, C;Blockx, I;Summer, P;Michael, J;Hamaide, J;Kreutzer, C;Boutin, H;Couillard-Després, S;Verhoye, M;Van der Linden, A;
2018
30445024
November 13th, 2018
Belgium
Bio-Imaging Lab, University of Antwerp, Universiteitsplein 1, Wilrijk, Antwerp 2610, Belgium
NCLX prevents cell death during adrenergic activation of the brown adipose tissue
bioRxiv
Assali, E;Jones, A;Veliova, M;Taha, M;Miller, N;Shum, M;Oliveira, M;Las, G;Liesa, M;Sekler, I;Shirihai, O;
2018
November 7th, 2018
UCLA
Leukemia development initiated by deletion of RBP-J: mouse strain, deletion efficiency, and cell of origin
Dis Model Mech
Belyea, BC;Xu, F;Sequeira-Lopez, MLS;Gomez, RA;
2018
30467111
November 22nd, 2018
United States
Department of Pediatrics, University of Virginia School of Medicine, MR4 Building, 409 Lane Road, Charlottesville, VA 22908, USA
The HDAC3-SMARCA4-miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma
Sci Signal
Bharathy, N;Berlow, NE;Wang, E;Abraham, J;Settelmeyer, TP;Hooper, JE;Svalina, MN;Ishikawa, Y;Zientek, K;Bajwa, Z;Goros, MW;Hernandez, BS;Wolff, JE;Rudek, MA;Xu, L;Anders, NM;Pal, R;Harrold, AP;Davies, AM;Ashok, A;Bushby, D;Mancini, M;Noakes, C;Goodwin, NC;Ordentlich, P;Keck, J;Hawkins, DS;Rudzinski, ER;Chatterjee, B;Bächinger, HP;Barr, FG;Liddle, J;Garcia, BA;Mansoor, A;Perkins, TJ;Vakoc, CR;Michalek, JE;Keller, C;
2018
30459282
November 20th, 2018
United States
Children's Cancer Therapy Development Institute, Beaverton, OR 97005, USA
Placental Macrophages: A Window Into Fetal Microglial Function in Maternal Obesity
Int. J. Dev. Neurosci.
Edlow, AG;Glass, RM;Smith, CJ;Tran, PK;James, K;Bilbo, S;
2018
30465871
November 20th, 2018
United States
Obstetrics, Gynecology, and Reproductive Biology, Harvard Medical School; Massachusetts General Hospital, Vincent Center for Reproductive Biology
Early impacts of modified food consistency on oromotor outcomes in mouse models of Down syndrome
Physiol. Behav.
Glass, TJ;Twadell, SL;Valmadrid, LC;Connor, NP;
2018
30496741
November 26th, 2018
United States
Department of Surgery, University of Wisconsin, Madison, WI, USA
Macrophage Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer
bioRxiv
Halbrook, C;Pontious, C;Lee, H;Kovalenko, I;Zhang, Y;Lapienyte, L;Dreyer, S;Kremer, D;Sajjakulnukit, P;Zhang, L;Nelson, B;Hong, H;Kemp, S;Chang, D;Biankin, A;Crawford, H;Morton, J;Pasca di Magliano, M;Lyssiotis, C;
2018
November 5th, 2018
United States
University of Michigan
Diet-Induced Insulin Resistance Elevates Hippocampal Glutamate as well as VGLUT1 and GFAP Expression in AßPP/PS1 Mice
J. Neurochem.
Hascup, ER;Broderick, SO;Russell, MK;Fang, Y;Bartke, A;Boger, HA;Hascup, KN;
2018
30472734
November 25th, 2018
Department of Neurology, Center for Alzheimer's Disease and Related Disorders, Neurosciences Institute
NLRP3 Promotes Diabetic Bladder Dysfunction and Changes in Symptom-Specific Bladder Innervation
Diabetes
Hughes, FM;Hirshman, NA;Inouye, BM;Jin, H;
2018
30425063
Foxc2 is required for proper cardiac neural crest cell migration, outflow tract septation, and ventricle expansion
Dev. Dyn.
Inman, KE;Caiaffa, CD;Melton, KR;Sandell, LL;Achilleos, A;Kume, T;Trainor, PA;
2018
30376688
December 1st, 2018
United States
Department of Natural Sciences, Shawnee State University, Portsmouth, Ohio
Direct intracellular signaling by the carboxy terminus of NMDA receptor GluN2 subunits regulates dendritic morphology in hippocampal CA1 pyramidal neurons
Neuroscience
Keith, RE;Azcarate, JM;Keith, MJ;Hung, CW;Badakhsh, MF;Dumas, TC;
2018
30471357
November 21st, 2018
United States
Interdisciplinary Program in Neuroscience, United States; Krasnow Institute of Advanced Study, George Mason University, Fairfax, VA 22030, United States
Investigating the Role of the Growth Hormone Secretagogue Receptor in Food-Motivated Behaviours
Thesis
King, S;
2018
November 13th, 2018
Carleton University Ottawa, ON
Increased susceptibility to cortical spreading depression and epileptiform activity in a mouse model for FHM2
Sci Rep
Kros, L;Lykke-Hartmann, K;Khodakhah, K;
2018
30446731
November 16th, 2018
Netherlands
Dominick P. Purpura Department of Neuroscience, Albert Einstein College of Medicine, 1410 Pelham Parkway South, Bronx, NY, 10461, USA
Establishing sleep stages using Delta, Theta and Gamma oscillations from long term Local Field Potential (LFP) recordings in mice
researchgate.net
Molnar, L;Hungarian, S;Domokos, J;Ferando, I;Mody, I;
2018
Oman
Department of Electrical Engineering Sapientia Hungarian University of Transylvania Târgu-Mures, Romania
Knock-in rat lines with Cre recombinase at the dopamine D1 and adenosine 2a receptor loci. - bioRxiv
Knock-in rat lines with Cre recombinase at the dopamine D1 and adenosine 2a receptor loci.
bioRxiv
Pettibone, J;Yu, J;Herman, R;Hughes, E;Filipiak, W;Zeidler, M;Saunders, T;Ferrario, C;Berke, J;
2018
October 29th, 2018
United States
University of California San Francisco
Phenotypic Modulation of Skeletal Muscle Fibers in LPIN1-Deficient Lipodystrophic ( fld) Mice
Vet. Pathol.
Sellers, RS;Mahmood, SR;Perumal, GS;Macaluso, FP;Kurland, IJ;
2018
30381013
October 31st, 2018
United States
1 Department of Pathology, Albert Einstein College of Medicine, Bronx, NY, USA
CHARACTERIZING AQP9: A REGULATOR OF EPIPHYSEAL PLATE CHONDROCYTE PROLIFERATION, HYPERTROPHY, AND LONG BONE GROWTH
Thesis
Tang, P;
2018
1-(4-nitrobenzenesulfonyl)-4-penylpiperazine increases the number of Peyer’s patch-associated regenerating crypts in the small intestines after radiation injury
Radiotherapy and Oncology
Bhat, K;Duhachek-Muggy, S;Ramanathan, R;Saki, M;Alli, C;Medina, P;Damoiseaux, R;Whitelegge, J;McBride, W;Schaue, D;Vlashi, E;Pajonk, F;
2019
March 1st, 2019
United States
Department of Radiation Oncology, David Geffen School of Medicine, University of California at Los Angeles, USA
Improving Outcomes in NF1 Spine Fusion
Thesis
Bobyn, JD;
2018
Australia
Arkadia degrades SNON to activate level-specific NODAL responses
bioRxiv
Carthy, J;Ioannou, M;Episkopou, V;
2018
December 5th, 2018
Department of Medicine, Division of Brain Sciences, Imperial College London
Salmonella Persist in Activated Macrophages in T Cell-Sparse Granulomas but Are Contained by Surrounding CXCR3 Ligand-Positioned Th1 Cells
Immunity
Goldberg, MF;Roeske, EK;Ward, LN;Pengo, T;Dileepan, T;Kotov, DI;Jenkins, MK;
2018
30552021
December 18th, 2018
United States
Center for Immunology, Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA
Multiple receptors converge on H2-Q10 to regulate NK & γδT cell development
Immunology and Cell Biology
Goodall, KJ;Nguyen, A;Matsumoto, A;McMullen, JR;Eckle, SB;Bertolino, P;Sullivan, LC;Andrews, DM;
2018
30537346
December 9th, 2018
Australia
Department of Immunology and Pathology, Central Clinical School, Monash University, Melbourne, Australia
Early Life Stress Drives Sex-Selective Impairment in Reversal Learning by Affecting Parvalbumin Interneurons in Orbitofrontal Cortex of Mice
Cell Rep
Goodwill, HL;Manzano-Nieves, G;LaChance, P;Teramoto, S;Lin, S;Lopez, C;Stevenson, RJ;Theyel, BB;Moore, CI;Connors, BW;Bath, KG;
2018
30485800
November 27th, 2018
United States
Department of Neuroscience, Brown University, Providence, RI 02912, USA
Sox9 regulates cell state and activity of embryonic mouse mammary progenitor cells
Communications Biology
Kogata, N;Bland, P;Tsang, M;Oliemuller, E;Lowe, A;Howard, BA;
2018
30564749
December 13th, 2018
United Kingdom
1The Breast Cancer Now Toby Robins Research Centre, Division of Breast Cancer Research, The Institute of Cancer Research, London, UK
A Novel hAPP/htau Mouse Model of Alzheimer's Disease: Inclusion of APP With Tau Exacerbates Behavioral Deficits and Zinc Administration Heightens Tangle Pathology
Front Aging Neuroscience
Lippi, SLP;Smith, ML;Flinn, JM;
2018
30524268
November 22nd, 2018
United States
Psychology Department, George Mason University, Fairfax, VA, United States
Sex- and Development-Dependent Responses of Rat Microglia to Pro- and Anti-inflammatory Stimulation
Front Cell Neuroscience
Lively, S;Wong, R;Lam, D;Schlichter, LC;
2018
30524242
November 20th, 2018
Canada
Division of Genetics & Development, Krembil Research Institute, University Health Network, Toronto, ON, Canada
The Effect of Maternal Obesity on Placental Cell-Free DNA Release in a Mouse Model
Reproductive Sciences
Mhatre, M;Adeli, S;Norwitz, E;Craigo, S;Phillippe, M;Edlow, A;
2018
30453834
November 19th, 2018
United States
1 Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Tufts Medical Center, Boston, MA, USA
Sudden heart rate reduction upon optogenetic release of acetylcholine from cardiac parasympathetic neurons in perfused hearts
bioRxiv
Moreno, A;Endicott, K;Skancke, M;Dwyer, M;Brennan, J;Efimov, I;Trachiotis, G;Mendelowitz, D;Kay, M;
2018
October 24th, 2018
United States
Department of Biomedical Engineering, The George Washington University, 800 22nd Street NW, Suite 5000, Washington, DC 20052, USA
A sensorimotor pathway via higher-order thalamus
Journal of Neuroscience
Mo, C;Sherman, SM;
2018
30504278
November 30th, 2018
United States
Department of Neurobiology, University of Chicago, Chicago, Illinois, 60637
Harnessing Genetic Complexity to Enhance Translatability of Alzheimer's Disease Mouse Models: A Path toward Precision Medicine
Neuron
Neuner, SM;Heuer, SE;Huentelman, MJ;O'Connell, KMS;Kaczorowski, CC;
2018
30595332
December 21st, 2018
United States
The Neuroscience Institute, University of Tennessee Health Science Center, Memphis, TN 38163, USA; The Jackson Laboratory, Bar Harbor, ME 04609, USA
The α7 nicotinic acetylcholine receptors regulate hippocampal adult-neurogenesis in a sexually dimorphic fashion
Brain Structure and Function
Otto, SL;Yakel, JL;
2018
30515567
December 4th, 2018
United States
Neurobiology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, P.O. box 12233, Mail Drop F2-08, Research Triangle Park, NC, 27709, USA
Cellular interactions underpinning the immunomodulatory action of mesenchymal stromal cells in models of liver transplant injury
Thesis
Owen, AP;
2018
United Kingdom
LCAT Enzyme Replacement Therapy Reduces LpX and Improves Kidney Function in a Mouse Model of Familial LCAT Deficiency
Journal of Pharmacology and Experimental Therapeutics
Vaisman, BL;Neufeld, EB;Freeman, LA;Gordon, SM;Sampson, ML;Pryor, M;Hillman, E;Axley, MJ;Karathanasis, SK;Remaley, AT;
2018
30563940
December 18th, 2018
United States
NHLBI, NIH
SETD3 is an actin histidine methyltransferase that prevents primary dystocia
Nature
Wilkinson, A;Diep, J;Dai, S;Liu, S;Ooi, Y;Song, D;Li, T;Horton, J;Zhang, X;Liu, C;Trivedi, D;Ruppel, K;Vilches-Moure, J;Casey, K;Mak, J;Cowan, T;Elias, J;Nagamine, C;Spudich, J;Cheng, X;Carette, J;Gozani, O;
2018
December 10th, 2018
United States
Department of Biology, Stanford University, Stanford, CA, USA