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Category: annals of otology, rhinology and laryngology

Dual targeting of p53 and c-MYC selectively eliminates leukaemic stem cells - Nature
Real-time in vivo imaging reveals localised Nrf2 stress responses associated with direct and metabolism-dependent drug toxicity - Scientific Reports
Ischemic Preconditioning Protects Astrocytes against Oxygen Glucose Deprivation Via the Nuclear Erythroid 2-Related Factor 2 Pathway - Translational Stroke Research
Biomechanical forces promote embryonic haematopoiesis - Nature
RAS and RHO families of GTPases directly regulate distinct phosphoinositide 3-kinase isoforms - Cell
Hunger states switch a flip-flop memory circuit via a synaptic AMPK-dependent positive feedback loop - Cell
Genetic tracing via DNGR-1 expression history defines dendritic cells as a hematopoietic lineage - Cell
The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-ë_ locus - Cell
The retinoblastoma binding protein RBP2 is an H3K4 demethylase - Cell
Hijacking the neuronal NMDAR signaling circuit to promote tumor growth and invasion - Cell
Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML - Cell
53BP1 regulates DSB repair using Rif1 to control 5'' end resection - Science
Thalamic miR-338-3p mediates auditory thalamocortical disruption and its late onset in models of 22q11.2 microdeletion - Nature Medicine
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses - Nature Medicine
Combined inhibition of DDR1 and Notch signaling is a therapeutic strategy for KRAS-driven lung adenocarcinoma - Nature Medicine
Loss of BAP1 function leads to EZH2-dependent transformation - Nature Medicine
Epidermal growth factor regulates hematopoietic regeneration after radiation injury - Nature Medicine
DNA sequencing: generation next-next - Nature Methods
IL-37 requires the receptors IL-18Rë± and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction - Nature Immunology
The PYRIN domain-only protein POP3 inhibits ALR inflammasomes and regulates responses to infection with DNA viruses - Nature Immunology
c-Raf, but not B-Raf, is essential for development of K-Ras oncogene-driven non-small cell lung carcinoma - Cancer Cell
The ALK(F1174L) mutation potentiates the oncogenic activity of MYCN in neuroblastoma - Cancer Cell
Calcification of multipotent prostate tumor endothelium - Cancer Cell
Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling - Nature Cell Biology
Suppression of microRNA activity amplifies IFN-ë_-induced macrophage activation and promotes anti-tumour immunity - Nature Cell Biology
PET imaging of leptin biodistribution and metabolism in rodents and primates - Cell Metabolism
Imaging activity in neurons and glia with a Polr2a-based and cre-dependent GCaMP5G-IRES-tdTomato reporter mouse - Neuron
Sexual divergence in microtubule function: the novel intranasal microtubule targeting SKIP normalizes axonal transport and enhances memory - Molecular Psychiatry
Identification of neurodegenerative factors using translatome-regulatory network analysis - Nature Neuroscience
Diminished KCC2 confounds synapse specificity of LTP during senescence - Nature Neuroscience
AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training - Nature Neuroscience
Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in CCR2-/- mice: evidence for independent chemokine functions in atherogenesis - Circulation
TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres - Molecular Cell
Inhibition of Tumor Growth and Metastasis in Pancreatic Cancer Models by Interference With CD44v6 Signaling - Gastroenterology
Ca2+ responses in enteric glia are mediated by connexin-43 hemichannels and modulate colonic transit in mice - Gastroenterology
NOS1-derived nitric oxide promotes NF-ë¼B transcriptional activity through inhibition of suppressor of cytokine signaling-1 - Journal of Experimental Medicine
Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression - Journal of Clinical Investigation
Foxc1 and Foxc2 deletion causes abnormal lymphangiogenesis and correlates with ERK hyperactivation - Journal of Clinical Investigation
NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth - Journal of Clinical Investigation
Lack of protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis - Journal of Clinical Investigation
Neurovascular crosstalk between interneurons and capillaries is required for vision - Journal of Clinical Investigation
Targeting mTOR dependency in pancreatic cancer - Gut
Ketone bodies mediate antiseizure effects through mitochondrial permeability transition - Annals of Neurology
Matrix metalloproteinase 3 deletion preserves denervated motor endplates after traumatic nerve injury - Annals of Neurology
Periostin is required for maximal airways inflammation andåÊhyperresponsiveness in mice - Journal of Allergy and Clinical Immunology
Endothelial cell-dependent regulation of arteriogenesis - Circulation Research
Biallelic Mutations in PDE10A Lead to Loss of Striatal PDE10A and a Hyperkinetic Movement Disorder with Onset in Infancy - American Journal of Human Genetics
Transduction of group I mGluR-mediated synaptic plasticity by ë_-arrestin2 signalling - Nature Communications
A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa - Nature Communications
P-Rex1 is required for efficient melanoblast migration and melanoma metastasis - Nature Communications
Inflammation-driven carcinogenesis is mediated through STING - Nature Communications
Mek1/2 MAPK kinases are essential for Mammalian development, homeostasis, and Raf-induced hyperplasia - Developmental Cell
Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits - Developmental Cell
TRPC6 channel translocation into phagosomal membrane augments phagosomal function - Proceedings of the National Academy of Sciences of the United States of America
Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity - Proceedings of the National Academy of Sciences of the United States of America
Notch3 drives development and progression of cholangiocarcinoma - Proceedings of the National Academy of Sciences of the United States of America
Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer - Proceedings of the National Academy of Sciences of the United States of America
Striosome-dendron bouquets highlight a unique striatonigral circuit targeting dopamine-containing neurons - Proceedings of the National Academy of Sciences of the United States of America
Identification of cancer initiating cells in K-Ras driven lung adenocarcinoma - Proceedings of the National Academy of Sciences of the United States of America
Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation - Proceedings of the National Academy of Sciences of the United States of America
HER2 overcomes PTEN (loss)-induced senescence to cause aggressive prostate cancer - Proceedings of the National Academy of Sciences of the United States of America
Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice - Proceedings of the National Academy of Sciences of the United States of America
Cystic fibrosis transmembrane conductance regulator with a shortened R domain rescues the intestinal phenotype of CFTR-/- mice - Proceedings of the National Academy of Sciences of the United States of America
The preproghrelin gene is required for the normal integration of thermoregulation and sleep in mice - Proceedings of the National Academy of Sciences of the United States of America
CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo - Proceedings of the National Academy of Sciences of the United States of America
STING manifests self DNA-dependent inflammatory disease - Proceedings of the National Academy of Sciences of the United States of America
A human IL10 BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome - Proceedings of the National Academy of Sciences of the United States of America
Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst - Proceedings of the National Academy of Sciences of the United States of America
Modified activin receptor IIB ligand trap mitigates ineffective erythropoiesis and disease complications in murine ë_-thalassemia - Blood
FGF signaling facilitates postinjury recovery of mouse hematopoietic system - Blood
Targeting vasculogenesis to prevent progression in multiple myeloma - Leukemia
p120 Catenin Suppresses Basal Epithelial Cell Extrusion in Invasive Pancreatic Neoplasia - Cancer Research
Deregulated estrogen receptor alpha and p53 heterozygosity collaborate in the development of mammary hyperplasia - Cancer Research
STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma - Cancer Research
Obesity promotes breast cancer by CCL2-mediated macrophage recruitment and angiogenesis - Cancer Research
A novel mouse model that develops spontaneous arthritis and is predisposed towards atherosclerosis - Annals of Rheumatic Diseases
The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis - Oncogene
In vivo oncogenic conflict triggered by co-existing KRAS and EGFR activating mutations in lung adenocarcinoma - Oncogene
TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis - Oncogene
Mek1/2 gene dosage determines tissue response to oncogenic Ras signaling in the skin - Oncogene
Functions of TAp63 and p53 in restraining the development of metastatic cancer - Oncogene
p53 mutations cooperate with oncogenic Kras to promote adenocarcinoma from pancreatic ductal cells - Oncogene
C-terminal threonines and serines play distinct roles in the desensitization of rhodopsin, a G protein-coupled receptor - Elife
Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel - Elife
Hypoxia-induced metabolic stress in retinal pigment epithelial cells is sufficient to induce photoreceptor degeneration - Elife
Sex differences in cerebellar synaptic transmission and sex-specific responses to autism-linked Gabrb3 mutations in mice - Elife
Kindlin1 regulates microtubule function to ensure normal mitosis - Journal of Molecular Cell Biology
Matrix metalloproteinase-20 mediates dental enamel biomineralization by preventing protein occlusion inside apatite crystals - Biomaterials
Disrupted Cortical State Regulation in a Rat Model of Fragile X Syndrome - Cerebral Cortex
Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy - EMBO Molecular Medicine
SPRY2 loss enhances ErbB trafficking and PI3K/AKT signalling to drive human and mouse prostate carcinogenesis - EMBO Molecular Medicine
p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium - EMBO Molecular Medicine
Differential role of lipocalin 2 during immune complex-mediated acute and chronic inflammation in mice - Arthritis & Rheumatology
Requirement of myeloid cell-specific Fas expression for prevention of systemic autoimmunity in mice - Arthritis & Rheumatology
Role of ë_4* Nicotinic Acetylcholine Receptors in the Habenulo-Interpeduncular Pathway in Nicotine Reinforcement in Mice - Neuropsychopharmacology
Forebrain-specific CRF overproduction during development is sufficient to induce enduring anxiety and startle abnormalities in adult mice - Neuropsychopharmacology
NADPH Oxidase-Dependent NLRP3 Inflammasome Activation and its Important Role in Lung Fibrosis by Multiwalled Carbon Nanotubes - Small
CXCR2 inhibition suppresses acute and chronic pancreatic inflammation - Journal of Pathology
Fibroblast growth factor receptor 3 activation plays a causative role in urothelial cancer pathogenesis in cooperation with Pten loss in mice - Journal of Pathology
Vertebrate Host Susceptibility to Heartland Virus - Emerging Infectious Diseases
Telomere-Internal Double-Strand Breaks Are Repaired by Homologous Recombination and PARP1/Lig3-Dependent End-Joining - Cell Reports
Expression of BCR/ABL p210 from a knockin allele enhances bone marrow engraftment without inducing neoplasia - Cell Reports
Role of angiopoietin-2 in adaptive tumor resistance to VEGF signaling blockade - Cell Reports
Pten loss in Olig2 expressing neural progenitor cells and oligodendrocytes leads to interneuron dysplasia and leukodystrophy - Stem Cells
Target-derived neurotrophins coordinate transcription and transport of bclw to prevent axonal degeneration - Journal of Neuroscience
Fatty Acid-Binding Protein 5 at the Blood-Brain Barrier Regulates Endogenous Brain Docosahexaenoic Acid Levels and Cognitive Function - Journal of Neuroscience
The Angelman syndrome protein Ube3a/E6AP is required for Golgi acidification and surface protein sialylation - Journal of Neuroscience
Homeostatic responses fail to correct defective amygdala inhibitory circuit maturation in fragile X syndrome - Journal of Neuroscience
PIP2-mediated HCN3 channel gating is crucial for rhythmic burst firing in thalamic intergeniculate leaflet neurons - Journal of Neuroscience
Mature mice lacking Rbl2/p130 gene have supernumerary inner ear hair cells and supporting cells - Journal of Neuroscience
The p38ë± MAPK regulates microglial responsiveness to diffuse traumatic brain injury - Journal of Neuroscience
PPARë_ recruitment to active ERK during memory consolidation is required for Alzheimer''s disease-related cognitive enhancement - Journal of Neuroscience
Sensory neuropathy attributable to loss of Bcl-w - Journal of Neuroscience
Circuit-specific intracortical hyperconnectivity in mice with deletion of the autism-associated Met receptor tyrosine kinase - Journal of Neuroscience
Dendritic HCN2 channels constrain glutamate-driven excitability in reticular thalamic neurons - Journal of Neuroscience
A new mouse model for stationary night blindness with mutant Slc24a1 explains the pathophysiology of the associated human disease - Human Molecular Genetics
CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy - Human Molecular Genetics
Reduction of ciliary length through pharmacologic or genetic inhibition of CDK5 attenuates polycystic kidney disease in a model of nephronophthisis - Human Molecular Genetics
Lipid-enriched diet rescues lethality and slows down progression in a murine model of VCP-associated disease - Human Molecular Genetics
Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related polycystic kidney disease - Human Molecular Genetics
Glycogen accumulation underlies neurodegeneration and autophagy impairment in Lafora disease - Human Molecular Genetics
AKT regulates NPM dependent ARF localization and p53mut stability in tumors - Oncotarget
The role of apoptosis in immune hyporesponsiveness following AAV8 liver gene transfer - Molecular Therapy
Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling - Journal of Investigative Dermatology
ë±5 and ë±v integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo - Development
Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle - Development
Phenotypic analysis of mice completely lacking netrin 1 - Development
Endothelial alpha5 and alphav integrins cooperate in remodeling of the vasculature during development - Development
Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development - Development
Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation - Development
The neuron-specific interleukin-1 receptor accessory protein is required for homeostatic sleep and sleep responses to influenza viral challenge in mice - Brain Behavior and Immunity
Sickness behaviour after lipopolysaccharide treatment in ghrelin deficient mice - Brain Behavior and Immunity
Specific suppression of insulin sensitivity in growth hormone receptor gene-disrupted (GHR-KO) mice attenuates phenotypic features of slow aging - Aging Cell
Sensitization of nociceptive spinal neurons contributes to pain in a transgenic model of sickle cell disease - Pain
Optogenetic release of norepinephrine from cardiac sympathetic neurons alters mechanical and electrical function - Cardiovascular Research
NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis - Free Radical Biology and Medicine
Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury - Free Radical Biology and Medicine
Chk1 is essential for the development of murine epidermal melanocytes - Pigment Cell and Melanoma Research
Differential effects of NOX4 and NOX1 on immune cell-mediated inflammation in the aortic sinus of diabetic ApoE-/- mice - Clinical Science
Use of a genetically engineered mouse model as a preclinical tool for HER2 breast cancer - Disease Models and Mechanisms
CK2 activity is required for the interaction of FGF14 with voltage-gated sodium channels and neuronal excitability - FASEB Journal
Sustained nitric oxide (NO)-releasing compound reverses dysregulated NO signal transduction in priapism - FASEB Journal
Proceedings of the Second Shanthi V. Sitaraman Intestinal Pathobiology Symposium - Inflammory Bowel Disorder Journal
Cathelicidin suppresses lipid accumulation and hepatic steatosis by inhibition of the CD36 receptor - International Journal of Obesity (Lond)
Intrauterine group A streptococcal infections are exacerbated by prostaglandin E2 - Journal of Immunology
The class A scavenger receptor, macrophage receptor with collagenous structure, is the major phagocytic receptor for Clostridium sordellii expressed by human decidual macrophages - Journal of Immunology
Characterization of human antiviral adaptive immune responses during hepatotropic virus infection in HLA-transgenic human immune system mice - Journal of Immunology
Intrinsic self-DNA triggers inflammatory disease dependent on STING - Journal of Immunology
Beta1 integrin is an adhesion protein for sperm binding to eggs - ACS Chemical Biology
Microglial p38ë± MAPK is critical for LPS-induced neuron degeneration, through a mechanism involving TNFë± - Molecular Neurodegeneration
Fibroblast Growth Factor 14 Modulates the Neurogenesis of Granule Neurons in the Adult Dentate Gyrus - Molecular Neurobiology
Role of ERalpha in the differential response of Stat5a loss in susceptibility to mammary preneoplasia and DMBA-induced carcinogenesis - Carcinogenesis
NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium - Journal of Molecular and Cellular Cardiology
Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington''s disease - Neurobiology of Disease
Mitochondrial dysfunction in an Opa1(Q285STOP) mouse model of dominant optic atrophy results from Opa1 haploinsufficiency - Cell Death Discovery
Protease induced plasticity: matrix metalloproteinase-1 promotes neurostructural changes through activation of protease activated receptor 1 - Scientific Reports
Electroacupuncture in conscious free-moving mice reduces pain by ameliorating peripheral and central nociceptive mechanisms - Scientific Reports
Macrophages form functional vascular mimicry channels in vivo - Scientific Reports
miR-182 Modulates Myocardial Hypertrophic Response Induced by Angiogenesis in Heart - Scientific Reports
Sensory hypo-excitability in a rat model of fetal development in Fragile X Syndrome - Scientific Reports
The astrocytic transporter SLC7A10 (Asc-1) mediates glycinergic inhibition of spinal cord motor neurons - Scientific Reports
Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis - Scientific Reports
Magnetic Resonance Spectroscopy discriminates the response to microglial stimulation of wild type and Alzheimer''s disease models - Scientific Reports
Microfluidic squeezing for intracellular antigen loading in polyclonal B-cells as cellular vaccines - Scientific Reports
Crumbs3 is essential for proper epithelial development and viability - Molelcular and Cellular Biology
Enhanced Cognition and Hypoglutamatergic Signaling in a Growth Hormone Receptor Knockout Mouse Model of Successful Aging - Journals of Gerontology
Primary cancer cell culture: mammary-optimized vs conditional reprogramming - Endocrine Related Cancer
Microglial p38ë± MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Aë_) - Journal of Neuroinflammation
The p38alpha mitogen-activated protein kinase limits the CNS proinflammatory cytokine response to systemic lipopolysaccharide, potentially through an IL-10 dependent mechanism - Journal of Neuroinflammation
Age exacerbates the CCR2/5-mediated neuroinflammatory response to traumatic brain injury - Journal of Neuroinflammation
Deficiency of complement receptors CR2/CR1 in Cr2‰È/‰È mice reduces the extent of secondary brain damage after closed head injury - Journal of Neuroinflammation
Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease - Neurobiology of Aging
Accelerated protein damage in brains of PIMT+/- mice; a possible model for the variability of cognitive decline in human aging - Neurobiology of Aging
CB䉉 receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease - Molecular Medicine
Transcriptional dysregulation causes altered modulation of inhibition by haloperidol - Neuropharmacology
In vitro gamma oscillations following partial and complete ablation of ë« subunit-containing GABAA receptors from parvalbumin interneurons - Neuropharmacology
Monitoring cholinergic activity during attentional performance in mice heterozygous for the choline transporter: a model of cholinergic capacity limits - Neuropharmacology
Attenuated p53 activation in tumour-associated stromal cells accompanies decreased sensitivity to etoposide and vincristine - British Journal of Cancer
The ability of an attaching and effacing pathogen to trigger localized actin assembly contributes to virulence by promoting mucosal attachment - Cellular Microbiology
Fatty Acid-Binding Protein 5 Facilitates the Blood-Brain Barrier Transport of Docosahexaenoic Acid - Molecular Pharmaceutics
KISS1R signals independently of Gë±q/11 and triggers LH secretion via the ë_-arrestin pathway in the male mouse - Endocrinology
Reduced melanocortin production causes sexual dysfunction in male mice with POMC neuronal insulin and leptin insensitivity - Endocrinology
Delayed puberty but normal fertility in mice with selective deletion of insulin receptors from Kiss1 cells - Endocrinology
Mechanisms of amylin/leptin synergy in rodent models - Endocrinology
Regulation of brain PPARgamma2 contributes to ketogenic diet anti-seizure efficacy - Experimental Neurology
Preservation of neuromuscular function in symptomatic SOD1-G93A mice by peripheral infusion of methylene blue - Experimental Neurology
Desert hedgehog is a mediator of demyelination in compression neuropathies - Experimental Neurology
BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle - American Journal of Pathology
The PPARë_ agonist efatutazone increases the spectrum of well-differentiated mammary cancer subtypes initiated by loss of full-length BRCA1 in association with TP53 haploinsufficiency - American Journal of Pathology
The Dendritic Cell Major Histocompatibility Complex II (MHC II) Peptidome Derives from a Variety of Processing Pathways and Includes Peptides with a Broad Spectrum of HLA-DM Sensitivity - Journal of Biological Chemisrty
Hepatic Insulin Resistance Following Chronic Activation of the CREB Coactivator CRTC2 - Journal of Biological Chemisrty
Central Mechanisms Mediating Thrombospondin-4-induced Pain States - Journal of Biological Chemisrty
Purinergic control of hippocampal circuit hyperexcitability in Dravet syndrome - Epilepsia
In vivo ketogenic diet treatment attenuates pathologic sharp waves and high frequency oscillations in in vitro hippocampal slices from epileptic Kv 1.1ë± knockout mice - Epilepsia
Optogenetic stimulation of cholinergic brainstem neurons during focal limbic seizures: Effects on cortical physiology - Epilepsia
Ketogenic diet treatment increases longevity in Kcna1-null mice, a model of sudden unexpected death in epilepsy - Epilepsia
Ketogenic diet treatment abolishes seizure periodicity and improves diurnal rhythmicity in epileptic Kcna1-null mice - Epilepsia
Research tool: Validation of floxed ë±7 nicotinic acetylcholine receptor conditional knockout mice using in vitro and in vivo approaches - Journal of Physiology (London)
Fluorescence recovery after photobleaching reveals regulation and distribution of connexin36 gap junction coupling within mouse islets of Langerhans - Journal of Physiology (London)
Utrophin regulates modal gating of mechanosensitive ion channels in dystrophic skeletal muscle - Journal of Physiology (London)
CLC-3 chloride channels moderate long-term potentiation at Schaffer collateral-CA1 synapses - Journal of Physiology (London)
Physiological and morphological properties of Dbx1-derived respiratory neurons in the pre-Botzinger complex of neonatal mice - Journal of Physiology (London)
Is connexin36 critical for GABAergic hypersynchronization in the hippocampus? - Journal of Physiology (London)
Automated cell-specific laser detection and ablation of neural circuits in neonatal brain tissue - Journal of Physiology (London)
T-bet is essential for Th1-mediated, but not Th17-mediated, CNS autoimmune disease - European Journal of Immunology
CD40 engagement of CD4+ CD40+ T cells in a neo-self antigen disease model ablates CTLA-4 expression and indirectly impacts tolerance - European Journal of Immunology
Lineage tracking of mesenchymal and endothelial progenitors in BMP-induced bone formation - Bone
Activity-dependent neuroprotective protein (ADNP) exhibits striking sexual dichotomy impacting on autistic and Alzheimer's pathologies - Translational Psychiatry
The activin A antagonist follistatin inhibits cystic fibrosis-like lung inflammation and pathology - Immunology and Cell Biology
Mutation-independent rescue of a novel mouse model of Retinitis Pigmentosa - Gene Therapy
Ovarian cycle-linked plasticity of ë«-GABAA receptor subunits in hippocampal interneurons affects ë_ oscillations in vivo - Frontiers in Cellular Neuroscience
Regulation of ethanol intake under chronic mild stress: roles of dopamine receptors and transporters - Frontiers in Behavioral Neuroscience
TIR Domain-Containing Adapter-Inducing Beta Interferon (TRIF) Mediates Immunological Memory against Bacterial Pathogens - Infection and Immunity
SOCS-3 Regulates Alveolar Bone Loss in Experimental Periodontitis - Journal of Dental Research
Skeletal muscle glucose uptake during treadmill exercise in neuronal nitric oxide synthase-ë_ knockout mice - American Journal of Physiology Endocrinology and Metabolism
The absence of 25-hydroxyvitamin D3-1ë±-hydroxylase potentiates the suppression of EAE in mice by ultraviolet light - Journal of Steroid Biochemistry and Molecular Biology
Fibroblast-specific expression of AC6 enhances beta-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis - American Journal of Physiology Lung Cellular and Molecular Physiology
Periostin promotes fibrosis and predicts progression in patients with idiopathic pulmonary fibrosis - American Journal of Physiology Lung Cellular and Molecular Physiology
Toll-like receptor 2 mediates mesenchymal stem cell-associated myocardial recovery and VEGF production following acute ischemia-reperfusion injury - American Journal of Physiology Heart and Circulatory Physiology
ApoE deficiency exacerbates the development and sustainment of a semi-chronic K/BxN serum transfer-induced arthritis model - Journal of Translational Medicine
EP2 and EP4 receptors mediate PGE2 induced relaxation in murine colonic circular muscle: pharmacological characterization - Pharmacology Research
Males are from Mars, and females are from Venus: sex-specific fetal brain gene expression signatures in a mouse model of maternal diet-induced obesity - American Journal of Obsterics and Gynecology
Network of brain protein level changes in glutaminase deficient fetal mice - Journal of Proteomics
Neurological Dysfunction in Early Maturity of a Model for Niemann-Pick C1 Carrier Status - Neurotherapeutics
Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity - Journal of Pharmacology and Expreimental Therapeutics
Enhancing eNOS activity with simultaneous inhibition of IKKë_ restores vascular function in Ins2(Akita+/-) type-1 diabetic mice - Laboratory Investigation
Quantitative assessment of pancreatic cancer precursor lesions in IHC-stained tissue with a tissue image analysis platform - Laboratory Investigation
Mice lacking sialyltransferase ST3Gal-II develop late onset obesity and insulin resistance - Glycobiology
c-Met signalling is required for efficient postnatal thymic regeneration and repair - Immunology
Nervous-tissue-specific elimination of microtubule-actin crosslinking factor 1a results in multiple developmental defects in the mouse brain - Molecular and Cellular Neuroscience
Cooperative regulation of neurotransmitter release by Rab3a and synapsin II - Molecular and Cellular Neuroscience
Tissue inducible Lifeact expression allows visualization of actin dynamics in vivo and ex vivo - European Journal of Cell Biology
Mis-expression of the BK K(+) channel disrupts suprachiasmatic nucleus circuit rhythmicity and alters clock-controlled behavior - American Journal of Physiology, Cell Physiology
Delayed in vitro development of Up states but normal network plasticity in Fragile X circuits - European Journal of Neuroscience
Dopamine increases NMDA-stimulated calcium flux in striatopallidal neurons through a matrix metalloproteinase-dependent mechanism - European Journal of Neuroscience
Intact brown adipose tissue thermogenesis is required for restorative sleep responses after sleep loss - European Journal of Neuroscience
Impaired wake-promoting mechanisms in ghrelin receptor-deficient mice - European Journal of Neuroscience
5'-Ectonucleotidase-knockout mice lack non-REM sleep responses to sleep deprivation - European Journal of Neuroscience
RPGR-associated retinal degeneration in human X-linked RP and a murine model - Investigative Ophthalmology and Visual Science
L450W and Q455K Col8a2 knock-in mouse models of Fuchs endothelial corneal dystrophy show distinct phenotypes and evidence for altered autophagy - Investigative Ophthalmology and Visual Science
Altered Refractive Development in Mice With Reduced Levels of Retinal Dopamine - Investigative Ophthalmology and Visual Science
Isoaspartyl protein damage and repair in mouse retina - Investigative Ophthalmology and Visual Science
Reduced ocular blood flow as an early indicator of diabetic retinopathy in a mouse model of diabetes - Investigative Ophthalmology and Visual Science
The D-isoAsp-25 variant of histone H2B is highly enriched in active chromatin: potential role in the regulation of gene expression? - Amino Acids
WDR72 models of structure and function: a stage-specific regulator of enamel mineralization - Matrix Biology
p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas - Developmental Biology
A quantitative method for defining high-arched palate using the Tcof1(+/-) mutant mouse as a model - Developmental Biology
Integrin-ë±5ë_1 is not required for mural cell functions during development of blood vessels but is required for lymphatic-blood vessel separation and lymphovenous valve formation - Developmental Biology
Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice - Toxicology and Applied Pharmacology
MKP1-dependent PTH modulation of bone matrix mineralization in female mice is osteoblast maturation stage specific and involves P-ERK and P-p38 MAPKs - Journal of Endocrinology
Mitogen-activated protein kinase phosphatase 1 regulates bone mass, osteoblast gene expression, and responsiveness to parathyroid hormone - Journal of Endocrinology
Blood-brain barrier impairment in an animal model of MPS III B - PLOS ONE
Neonatal periostin knockout mice are protected from hyperoxia-induced alveolar simplication - PLOS ONE
Neuromuscular junction defects in mice with mutation of dynein heavy chain 1 - PLOS ONE
The nicotinic receptor Alpha7 impacts the mouse lung response to LPS through multiple mechanisms - PLOS ONE
Generation and Characterisation of a Pax8-CreERT2 Transgenic Line and a Slc22a6-CreERT2 Knock-In Line for Inducible and Specific Genetic Manipulation of Renal Tubular Epithelial Cells - PLOS ONE
A neonatal model of intravenous Staphylococcus epidermidis infection in mice <24 h old enables characterization of early innate immune responses - PLOS ONE
Nfatc2 and Tob1 have non-overlapping function in T cell negative regulation and tumorigenesis - PLOS ONE
Smad4 loss synergizes with TGFë± overexpression in promoting pancreatic metaplasia, PanIN development, and fibrosis - PLOS ONE
CRX is a diagnostic marker of retinal and pineal lineage tumors - PLOS ONE
Lamellipodin-Deficient Mice: A Model of Rectal Carcinoma - PLOS ONE
Insulin and Leptin Signaling Interact in the Mouse Kiss1 Neuron during the Peripubertal Period - PLOS ONE
Considerations in the identification of endogenous substrates for protein L-isoaspartyl methyltransferase: the case of synuclein - PLOS ONE
Liver-Specific Deletion of Phosphatase and Tensin Homolog Deleted on Chromosome 10 Significantly Ameliorates Chronic EtOH-Induced Increases in Hepatocellular Damage - PLOS ONE
Comparative Analysis of Pain Behaviours in Humanized Mouse Models of Sickle Cell Anemia - PLOS ONE
Isoaspartate accumulation in mouse brain is associated with altered patterns of protein phosphorylation and acetylation, some of which are highly sex-dependent - PLOS ONE
Generation and behavior characterization of CaMKIIë_ knockout mice - PLOS ONE
Parental diabetes: the Akita mouse as a model of the effects of maternal and paternal hyperglycemia in wildtype offspring - PLOS ONE
Digastric Muscle Phenotypes of the Ts65Dn Mouse Model of Down Syndrome - PLOS ONE
Rapamycin and chloroquine: the in vitro and in vivo effects of autophagy-modifying drugs show promising results in valosin containing protein multisystem proteinopathy - PLOS ONE
A Fine Balance of Dietary Lipids Improves Pathology of a Murine Model of VCP-Associated Multisystem Proteinopathy - PLOS ONE
Cholecystokinin: an excitatory modulator of mitral/tufted cells in the mouse olfactory bulb - PLOS ONE
Mechanism of testosterone deficiency in the transgenic sickle cell mouse - PLOS ONE
Novel marker for the onset of frontotemporal dementia: early increase in activity-dependent neuroprotective protein (ADNP) in the face of Tau mutation - PLOS ONE
Intrinsic susceptibility MRI identifies tumors with ALKF1174L mutation in genetically-engineered murine models of high-risk neuroblastoma - PLOS ONE
The effects of C75, an inhibitor of fatty acid synthase, on sleep and metabolism in mice - PLOS ONE
A reinforcing circuit action of extrasynaptic GABAA receptor modulators on cerebellar granule cell inhibition - PLOS ONE
Cranial irradiation alters the brain's microenvironment and permits CCR2+ macrophage infiltration - PLOS ONE
Deficiency in p38ë_ MAPK fails to inhibit cytokine production or protect neurons against inflammatory insult in in vitro and in vivo mouse models - PLOS ONE
Hilar somatostatin interneurons contribute to synchronized GABA activity in an in vitro epilepsy model - PLOS ONE
RDH10 oxidation of Vitamin A is a critical control step in synthesis of retinoic acid during mouse embryogenesis - PLOS ONE
7 Nicotinic receptor-mediated astrocytic gliotransmitter release: A effects in a preclinical Alzheimer's mouse model - PLOS ONE
Comprehensive analysis of ultrasonic vocalizations in a mouse model of fragile X syndrome reveals limited, call type specific deficits - PLOS ONE
GPR40 and GPR120 fatty acid sensors are critical for postoral but not oral mediation of fat preferences in the mouse - American Journal of Physiology Regulatory, Integrative and Comparative Physiology
P2X7 receptors in body temperature, locomotor activity, and brain mRNA and lncRNA responses to sleep deprivation - American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Sugar-induced cephalic-phase insulin release is mediated by a T1r2+T1r3-independent taste transduction pathway in mice - American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Restricted feeding-induced sleep, activity, and body temperature changes in normal and preproghrelin-deficient mice - American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Spontaneous sleep and homeostatic sleep regulation in ghrelin knockout mice - American Journal of Physiology Regulatory, Integrative and Comparative Physiology
SOD1-G93A mice exhibit muscle-fiber-type-specific decreases in glucose uptake in the absence of whole-body changes in metabolism - Neuro-degenerative Diseases
Effects of stimulus salience on touchscreen serial reversal learning in a mouse model of fragile X syndrome - Behavioral Brain Research
Sustained attention in mice: expanding the translational utility of the SAT by incorporating the Michigan Controlled Access Response Port (MICARP) - Behavioral Brain Research
A novel role for the immunophilin FKBP52 in motor coordination - Behavioral Brain Research
Neuronal nitric oxide synthase and NADPH oxidase interact to affect cognitive, affective, and social behaviors in mice - Behavioral Brain Research
Measures of bulbar and spinal motor function, muscle innervation, and mitochondrial function in ALS rats - Behavioral Brain Research
Spatial frequency threshold and contrast sensitivity of an optomotor behavior are impaired in the Ins2Akita mouse model of diabetes - Behavioral Brain Research
Molecular and behavioral profiling of Dbx1-derived neurons in the arcuate, lateral and ventromedial hypothalamic nuclei - Neural Development
Common and unique genetic interactions of the poly(ADP-ribose) polymerases PARP1 and PARP2 with DNA double-strand break repair pathways - DNA Repair
In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice - Drug Metabolism and Disposition
Pharmacokinetics of oral D-serine in D-amino acid oxidase knockout mice - Drug Metabolism and Disposition
Separation of function for classical and ganglion cell photoreceptors with respect to circadian rhythm entrainment and induction of photosomnolence - Neuroscience
Activation of the Wnt/ë_-catenin signaling cascade after traumatic nerve injury - Neuroscience
Distinct mechanisms of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrimidine resistance revealed by transcriptome mapping in mouse striatum - Neuroscience
Nuclear Thioredoxin-1 Overexpression Attenuates Alcohol-Mediated Nrf2 Signaling and Lung Fibrosis - Alcoholism Clinical and Experimental Research
Effects of Gabra2 Point Mutations on Alcohol Intake: Increased Binge-Like and Blunted Chronic Drinking by Mice - Alcoholism Clinical and Experimental Research
Galanin knockout mice show disturbances in ethanol consumption and expression of hypothalamic peptides that stimulate ethanol intake - Alcoholism Clinical and Experimental Research
Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication - Virology
Fragile X mental retardation protein regulates olfactory sensitivity but not odorant discrimination - Chemical Senses
Salty taste deficits in CALHM1 knockout mice - Chemical Senses
Normal Taste Acceptance and Preference of PANX1 Knockout Mice - Chemical Senses
Heightened avidity for trisodium pyrophosphate in mice lacking Tas1r3 - Chemical Senses
Ectopic POU5F1 in the male germ lineage disrupts differentiation and spermatogenesis in mice - Reproduction
Comprehensive motor testing in Fmr1-KO mice exposes temporal defects in oromotor coordination - Behavioral Neuroscience
Aryl hydrocarbon receptor knockout rats are insensitive to the pathological effects of repeated oral exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin - Journal of Applied Toxicology
Sildenafil promotes eNOS activation and inhibits NADPH oxidase in the transgenic sickle cell mouse penis - Journal of Sexual Medicine
Post-translational inactivation of endothelial nitric oxide synthase in the transgenic sickle cell mouse penis - Journal of Sexual Medicine
Extracellular sodium and potassium levels modulate cardiac conduction in mice heterozygous null for the Connexin43 gene - Pflugers Archiv - European Journal of Physiology
Astrocytic group I mGluR-dependent potentiation of astrocytic glutamate and potassium uptake - Journal of Neurophysiology
pigk Mutation underlies macho behavior and affects Rohon-Beard cell excitability - Journal of Neurophysiology
PACAP modulation of calcium ion activity in developing granule cells of the neonatal mouse olfactory bulb - Journal of Neurophysiology
Impact of inhibitory constraint of interneurons on neuronal excitability - Journal of Neurophysiology
Intragastric fat self-administration is impaired in GPR40/120 double knockout mice - Physiology and Behavior
MCH receptor deletion does not impair glucose-conditioned flavor preferences in mice - Physiology and Behavior
Ghrelin signaling is not essential for sugar or fat conditioned flavor preferences in mice - Physiology and Behavior
Macronutrient selection by seven inbred mouse strains and three taste-related knockout strains - Physiology and Behavior
Sucrose-conditioned flavor preferences in sweet ageusic T1r3 and Calhm1 knockout mice - Physiology and Behavior
Retinal macroglia changes in a triple transgenic mouse model of Alzheimer's disease - Experimental Eye Research
Intact Toll-like receptor 9 signaling in neutrophils modulates normal thrombogenesis in mice - Journal of Vasuclar Surgery
Morphine-induced antinociception and reward in humanized mice expressing the mu opioid receptor A118G polymorphism - Brain Research Bulletin
Altered gamma oscillations during pregnancy through loss of ë« subunit-containing GABA(A) receptors on parvalbumin interneurons - Frontiers in Neural Circuits
Severe drug-induced repetitive behaviors and striatal overexpression of VAChT in ChAT-ChR2-EYFP BAC transgenic mice - Frontiers in Neural Circuits
Distinct roles of synaptic and extrasynaptic GABAAreceptors in striatal inhibition dynamics - Frontiers in Neural Circuits
Cerebellar Nuclei Neurons Show Only Small Excitatory Responses to Optogenetic Olivary Stimulation in Transgenic Mice: In Vivo and In Vitro Studies - Frontiers in Neural Circuits
Conditional knockout of myocyte focal adhesion kinase abrogates ischemic preconditioning in adult murine hearts - Journal of American Heart Association
Reorganization of circuits underlying cerebellar modulation of prefrontal cortical dopamine in mouse models of autism spectrum disorder - Cerebellum
E-prostanoid 2 receptor signaling suppresses lung innate immunity against Streptococcus pneumoniae - Prostaglandins Other Lipid Mediators
Non-invasive quantification of brain tumor-induced astrogliosis - BMC Neuroscience
Suppression of brain cholesterol synthesis in male Mecp2-deficient mice is age dependent and not accompanied by a concurrent change in the rate of fatty acid synthesis - Brain Research
Long-term improvements in sensory inhibition with gestational choline supplementation linked to 7 nicotinic receptors through studies in Chrna7 null mutation mice - Brain Research
Taste dysfunction in BTBR mice due to a mutation of Itpr3, the inositol triphosphate receptor 3 gene - Physiological Genomics
Involvement of T1R3 in calcium-magnesium taste - Physiological Genomics
Lipoprotein(a) and vitamin C impair development of breast cancer tumors in Lp(a)+; Gulo-/- mice - International Journal of Oncology
Ascorbate supplementation inhibits growth and metastasis of B16FO melanoma and 4T1 breast cancer cells in vitamin C-deficient mice - International Journal of Oncology
Inhibition of neuronal p38ë±, but not p38ë_ MAPK, provides neuroprotection against three different neurotoxic insults - Journal of Molecular Neuroscience
Abstracts of the 10th International Symposium on VIP-PACAP and Related Peptides. December 13-16, 2011. Eilat, Israel - Journal of Molecular Neuroscience
Lentiviral-based approach for the validation of cancer therapeutic targets in vivo - BioTechniques
Intravital live cell triggered imaging system reveals monocyte patrolling and macrophage migration in atherosclerotic arteries - Journal of Biomedical Optics
Knockout of p11 attenuates the acquisition and reinstatement of cocaine conditioned place preference in male but not in female mice - Synapse
Evaluation of [å_‰üF]PFH PET renography to predict future disease progression in a rat model of autosomal dominant polycystic kidney disease - Nuclear Medicine and Biology
Quantification of pain in sickle mice using facial expressions and body measurements - Blood Cells, Molecules, and Diseases
Utrophin suppresses low frequency oscillations and coupled gating of mechanosensitive ion channels in dystrophic skeletal muscle - Channels (Austin)
A progressive translational mouse model of human valosin-containing protein disease: the VCP(R155H/+) mouse - Muscle Nerve
Circadian rhythmicity in serotonin transporter knockout mice - Life Sciences
Protection against vascular leak in neprilysin transgenic mice with complexåÊoverexpressionåÊpattern - Transgenic Research
A germline-competent embryonic stem cell line from NOD.Cg-Prkdc ( scid ) Il2rg ( tm1Wjl )/SzJ (NSG) mice - Transgenic Research
Effects of SB-269970, a 5-HT7 receptor antagonist, in mouse models predictive of antipsychotic-like activity - Behavioral Pharmacology
Inducible cell labeling and lineage tracking during fracture repair - Development, Growth, and Differentiation
Global gene expression profiling in R155H knock-in murine model of VCP disease - Clinical Transltional Science
ZASC1 knockout mice exhibit an early bone marrow-specific defect in murine leukemia virus replication - Virology Journal
Anticonvulsant effects of the selective melatonin receptor agonist ramelteon - Epilepsy and Behavior
Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure - American Journal of Medical Genetics Part A
Megaesophagus in a line of transgenic rats: a model of achalasia - Veterinary Pathology
Increased intake of ethanol and dietary fat in galanin overexpressing mice - Alcohol
Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice - Regulatory Peptides
Bacterial load and inflammation in fetal tissues is not dependent on IL-17a or IL-22 in 10-14 day pregnant mice infected with Listeria monocytogenes - Microbial Pathogenesis
Multiple ERbeta antisera label in ERbeta knockout and null mouse tissues - Journal of Neuroscience Methods
Prediction of death in the SMNëÓ7 mouse model of spinal muscular atrophy: insight into disease stage and progression - Journal of Neuroscience Methods
Activation of the NLRP3 Inflammasome Is Associated with Valosin-Containing Protein Myopathy - Inflammation
Attenuated Salmonella enterica Typhimurium reduces tumor burden in an autochthonous breast cancer model - Anticancer Research
Maneb causes pro-oxidant effects in the hippocampus of Nrf2 knockout mice - Environ.mental Toxicology and Pharmacology
Osteopontin does not mitigate cisplatin ototoxicity or nephrotoxicity in adult mice - Otolaryngology - Head and Neck Surgery
Relationship between circadian period and body size in the tau-mutant golden hamster - Canadian Journal of Physiology and Pharmacology
A comparative assessment of the cytotoxicity and nitric oxide reducing ability of resveratrol, pterostilbene and piceatannol in transformed and normal mouse macrophages - Drug and Chemical Toxicology
Cannabinoid receptor-specific mechanisms to alleviate pain in sickle cell anemia via inhibition of mast cell activation and neurogenic inflammation - Haematologica
Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease - Science Signaling
SLC26A4 targeted to the endolymphatic sac rescues hearing and balance in Slc26a4 mutant mice - PLOS Genetics
Interaction between Foxc1 and Fgf8 during mammalian jaw patterning and in the pathogenesis of syngnathia - PLOS Genetics
Transient Loss of Protection Afforded by a Live Attenuated Non-typhoidal Salmonella Vaccine in Mice Co-infected with Malaria - PLOS Neglected Tropical Diseases
Conditional deletion of caspase-8 in macrophages alters macrophage activation in a RIPK-dependent manner - Arthritis Research and Therapy
Short telomeres initiate telomere recombination in primary and tumor cells - PLOS Genetics
Small-molecule nociceptin receptor agonist ameliorates mast cell activation and pain in sickle mice - Haematologica
Ventral prostate fibrosis in the Akita mouse is associated with macrophage and fibrocyte infiltration - Journal of Diabetes Research
Salmonella enterica Typhimurium as a tumor-targeting immunotherapy vector - Thesis
How serotonin system alterations influence emotion-and cognition-related behaviors - Thesis
Neuron to microglia communication; a study of CX3CL1 signaling implications in cognitive function, inflammation, and neurodegeneration - Thesis
Investigation of the functional and structural role of podosomes in megakaryocytes - Thesis
Role of -Glucuronidase in the Chemopreventive Efficacy of Oral Curcumin: A Prodrug Hypothesis - Thesis
The Role of the Dopamine D1 Receptor in Cognition - Thesis
Role of Astrocytes in Ischemic Preconditioning-Induced Neuroprotection - Thesis
Functional characterisation of driver events in ovarian clear cell carcinoma - Thesis
Defining the role of Notch Signalling in Intrahepatic Cholangiocarcinoma - Thesis
Neuronal cicuits and reinforcement mechanisms underlying feeding behaviour - Thesis
Regulation of striatal medium spiny neuron GABAA receptor mediated tonic current - Thesis
COMBINATION IMMUNOTHERAPY TARGETING IMMUNOSUPPRESSIVE SIGNALS IN THE TUMOR MICROENVIRONMENT PREVENTS CANCER PROGRESSION - Thesis
Serotonergic Modulation of Glutamate Transmission: Bridging Two Theories of Depression - Thesis
THE ROLE OF PPAR- IN TROPHOBLAST LAYER DYNAMICS - Thesis
Defining the functional role of laminin isoforms in the regulation of the adult hepatic progenitor cell - Thesis
More than a License to Kill: Immune Regulation of Crohn's Disease by Natural Killer Cell and Its Clinical Implication - Thesis
Assessment of hepatic micronutrient disruption and the hepatotoxicity of 3, 3', 4, 4', 5-pentachlorobiphenyl (PCB126) - Thesis
Neuropilin-2 in pancreatic cancer and Semaphorin-3F as a treatment - Thesis
Cannabinoid CB1R Receptor Mediates Metabolic Syndrome in Models of Circadian and Glucocorticoid Dysregulation - Thesis
NEUROPILIN 2 EXPRESSION AND FUNCTION IN - Thesis
The role of Netrin-1 in semicircular canal morphogenesis - Thesis
The Role of Serotonin in the Development of Psychiatric Disorders: Studies on Drug Dependence and Anxiety-like Behaviour Following the Genetic Reduction of the - Thesis
Examining and improving the chemopreventive efficacy of curcumin - Thesis
RON Over-expression Induces Acinar-Ductal Metaplasia and Accelerates Tumorigenesis in a Kras Mutant Mouse Model of Pancreatic Cancer - Thesis
Study of functions of shelterins and telomerase in aging and nuclear reprograming - Thesis
The role of FGFR3 mutation in tumour initiation, progression and invasion of urothelial cell carcinoma in mice - Thesis
Requirement for fibroblast growth factor receptor 1 in hematopoietic stem cells under stress but not during homeostasis - Thesis
The Mechanism of Neuroprotection Mediated By Nicotinamide Mononucleotide Adenylyl Transferase (NMNAT) - Thesis
Investigating the role of caspase cleavage of ROCK1 in tissue homeostasis and tumour development - Thesis
The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming - Stem Cell Reports
Investigating downstream effectors of KRas signalling in vivo: Dusp6 and Fra1 - Thesis
In vivo characterization of pituitary adenylate cyclase-activating polypeptide in mouse olfactory epithelium - Thesis
Kiss 1 neurons and metabolic sensing - Thesis
Sex differences in the cardiac beta-adrenergic receptor contractile response - Thesis
Nutraceutical Antioxidants and Their Therapeutic Potential in Neurodegeneration - Thesis
AN INVESTIGATION INTO THE ROLE OF IRON, COPPER, AND GENDER IN A TRANSGENIC MOUSE MODEL OF ALZHEIMER'S DISEASE. - Thesis
Host cell factors involved in retrovirus replication and disease pathogenesis - Thesis
The mechanisms of reversal of refractory dysplasia in the salivary gland: Testing the role of p53, RXR and PPARgamma agonists, and PD0332991 - Thesis
Modulation of oncogenic transformation by Raf proteins - Thesis
The Effects of Specialized Proresolving Lipid Mediators on B Lymphocyte Function: Implications for B Cell Differentiation and Antibody Production - Thesis
Role of checkpoint kinase 1 in malignant melanoma - Thesis
Mechanisms of epithelial cell cancer generation: genetic risk factors on cancer progression investigated using in vivo models and at a single cell level - Thesis
p53 loss and Kras mutation in an invasive murine model of colorectal cancer - Thesis
Mechanisms that control the growth of cells in the presence of replication stress - Thesis
Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1 KO mice - Oncogenesis
Regulation of DMD pathology by an ankyrin-encoded miRNA - Skeletal Muscle
CNOT3-Dependent mRNA Deadenylation Safeguards the Pluripotent State - Stem Cell Reports
Pericyte structure and distribution in the cerebral cortex revealed by high-resolution imaging of transgenic mice - Neurophotonics
Transcription factor activator protein 2C and downstream redox biology effectors in development and carcinogenesis - Thesis
Crosstalk between the canonical NF-B and Notch signaling pathways inhibits Ppar expression and promotes pancreatic cancer progression in mice - The Journal of Clinical Investigation‰
Altered AIB1 or AIB13 expression impacts ER effects on mammary gland stromal and epithelial content - Molecular Endocrinology
Diphtheria toxin-mediated ablation of lymphatic endothelial cells results in progressive lymphedema - JCI Insight
Role of the Regulator of G protein Signaling 4 in renal ischemic reperfusion injury and repair - Thesis
Mapping Functional Brain Activation Using [14 C]-Iodoantipyrine in Male Serotonin Transporter Knockout Mice - PLOS ONE
Reduction in hSOD1 copy number significantly impacts ALS phenotype presentation in G37R (line 29) mice: implications for the assessment of putative therapeutic agents - Journal of Negative Results in Biomedicine
Biosynthesis of the major brain gangliosides GD1a and GT1b - Glycobiology
jul~ z, q. dol - Thesis
The Role of Dietary Copper and Zinc on Inflammation and Oxidative Stress in Alzheimer's Disease - Thesis
An Investigation into the Role of Copper Deficiency and Zinc in a Mouse Model of Early Onset Alzheimer's Disease. - Thesis
SELECTIVE MOLECULAR MODIFICATION TO CALCIUM CONDUCTANCE DOMAINS OF NMDA RECEPTOR GLUN2 SUBUNITS REGULATES MATURATION OF - Thesis
The role of neuropilin 2 in physiological and pathological angiogenesis - Thesis
Genome wide gene expression analysis of two ENU mouse models of major mental illness - Thesis
Identification of a maleimide-based glycogen synthase kinase-3 (GSK-3) inhibitor, BIP-135, that prolongs the median survival time of 7 SMA KO mouse model of - ACS Chemical Neuroscience
Receptor-Dependent Phagocytosis of Clostridium sordellii by Human Decidual Macrophages - Thesis
Contribution of Organic Cation Transporter 2 (OCT2) to CisplatinInduced Nephrotoxicity - Clinical Pharmacology &amp; Therapeutics
Synaptic molecular imaging in spared and deprived columns of mouse barrel cortex with array tomography - Scientific Data
Genetic Pharmacotherapy as an Early CNS Drug Development Strategy: Testing Glutaminase Inhibition for Schizophrenia Treatment in Adult Mice - Frontiers in Systems Neuroscience
Novel tubulin and tau neuroprotective fragments sharing structural similarities with the drug candidate NAP (Davuentide) - Journal of Alzheimers Disease
Deregulated estrogen receptor alpha-initiated preneoplasia and its progression: Role of STAT5A and cyclin D1 - Thesis
Human ApoE ëµ4 alters circadian rhythm activity, IL-1ë_, and GFAP in CRND8 mice - J. Alzheimers Dis.
The role of neuropilin 2 in physiological and pathological angiogenesis and lymphangiogenesis - Thesis
Further validation to support clinical translation of [(18)F]FTC-146 for imaging sigma-1 receptors - EJNMMI Res
Does Prenatal Valproate Interact with a Genetic Reduction in the Serotonin Transporter? A Rat Study on Anxiety and Cognition - Frontiers in Neuroscience
In vivo axonal transport deficits in a mouse model of fronto-temporal dementia - Neuroimage Clinical
Impact of the loss of caveolin-1 on lung mass and cholesterol metabolism in mice with and without the lysosomal cholesterol transporter, Niemann-Pick type C1 - Biochimica et Biophysica Acta Journal (BBA)
Quantitative Analysis of Supporting Cell Subtype Labeling Among CreER Lines in the Neonatal Mouse Cochlea - Journal of the Association for Research in Otolaryngology (JARO)
A Cystine-Rich Whey Supplement (Immunocal(å¨)) Delays Disease Onset and Prevents Spinal Cord Glutathione Depletion in the hSOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis - Antioxidants (Basel)
Deletion of the type-1 interferon receptor in APPSWE/PS1ëÓE9 mice preserves cognitive function and alters glial phenotype - Acta Neuropathologica Communications
Brain-specific interleukin-1 receptor accessory protein in sleep regulation - Journal of Applied Physiology
Modulating dopamine release by optogenetics in transgenic mice reveals terminal dopaminergic dynamics - Neurophotonics
Early exposure to environmental toxin contributes to neuronal vulnerability and axonal pathology in a model of familial ALS - Neuroscience &amp; Medicine
B cell and/or autoantibody deficiency do not prevent neuropsychiatric disease in murine systemic lupus erythematosus - Journal of Neuroinflammation
Community pharmacists' experience with pharmacogenetic testing - Journal of American Pharmicists Association (2003)
Metallothionein's role in PCB126 induced hepatotoxicity and hepatic micronutrient disruption - Toxicology Reports
Interaction of growth hormone receptor/binding protein gene disruption and caloric restriction for insulin sensitivity and attenuated aging - F1000Research
Ganglioside accumulation in glia during neurodegeneration and glial activation in the developing brain: Comparison between wild-type and GM2/GD2 synthase knock - Journal of Lipid Research
Identification of the pre-B̦tzinger complex inspiratory center in calibrated sandwich slices from newborn mice with fluorescent Dbx1 interneurons - Physiology Reports
Are Researchers Making the Most of Germ-Free Models? - Taconic
Generation of Kcnma1fl-tdTomato, a conditional deletion of the BK channel ë± subunit in mouse - Physiology Reports
Association of Over-Expressed Estrogen Receptor Alpha with Development of Tamoxifen Resistant Hyperplasia and Adenocarcinomas in Genetically Engineered Mice - Anatomy &amp; Physiology : Current Research
Administration of CoQ 10 analogue ameliorates dysfunction of the mitochondrial respiratory chain in a mouse model of Angelman syndrome - Neurobiology of Disease
Pendrin gene ablation alters ENaC subcellular distribution and open probability - American Journal of Physiology Renal Physiology
The role of the 7 subunit of the nicotinic acetylcholine receptor in the acute toxicosis of methyllycaconitine in mice - Journal of Applied Toxicology
Type II Cochlear Ganglion Neurons Do Not Drive the Olivocochlear Reflex: Re-Examination of the Cochlear Phenotype in Peripherin Knock-Out Mice - eNeuro
The CDK4/6 inhibitor PD0332991 reverses epithelial dysplasia associated with abnormal activation of the cyclin-CDK-Rb pathway - Cancer Prev Res (Phila)
Altered Responses to Cold Environment in Urocortin 1 and Corticotropin-Releasing Factor Deficient Mice - Physiology Journal
Obesity and diabetes cause cognitive dysfunction in the absence of accelerated ë_-amyloid deposition in a novel murine model of mixed or vascular dementia - Acta Neuropathologica Communications
Short Course - Pathobiology &amp; Phenotyping
2006 ALA Survey on Industrial Laboratory Automation - Journal of the Association for Laboratory Automation
Effects of cell-type specific hIL-10 expression on disease susceptibility (51.5) - The Journal of Immunology
ATP and the purine type 2 X7 receptor affect sleep - Journal of Applied Physiology
Ascorbate depletion increases growth and metastasis of melanoma cells in vitamin C deficient mice - Experimental Oncology
Nitric oxide reduces Cl‰È absorption in the mouse cortical collecting duct through an ENaC-dependent mechanism - American Journal of Physiology
Program and Abstracts of the 10th Transgenic Technology Meeting (TT2011) - Transgenic Research
Loss of Jagged1 in renin progenitors leads to focal kidney fibrosis - Physiology Reports
An LHX1-Regulated Transcriptional Network Controls Sleep/Wake Coupling and Thermal Resistance of the Central Circadian Clockworks - Current Biology
Injectable, Guest-Host Assembled Polyethylenimine Hydrogel for siRNA Delivery - Biomacromolecules
IL-15 Enables Septic Shock by Maintaining NK Cell Integrity and Function - Journal of Immunology
Interleukin 37 expression in mice alters sleep responses to inflammatory agents and influenza virus infection - Neurobiology of Sleep and Circadian Rhythms
Distinct Brca1 Mutations Differentially Reduce Hematopoietic Stem Cell Function - Cell Reports
Experimental Design and Data Analysis Issues Contribute to Inconsistent Results of C-Bouton Changes in Amyotrophic Lateral Sclerosis - eNeuro
Complement C5a receptor is the key initiator of neutrophil adhesion igniting immune complex‰ÛÒinduced arthritis - Science Immunology
Tumor-Infiltrating Merkel Cell Polyomavirus-Specific T Cells Are Diverse and Associated with Improved Patient Survival. - Cancer Immunology Research
Coordination by Cdc42 of Actin, Contractility, and Adhesion for Melanoblast Movement in Mouse Skin - Current Biology
CatSperë¦ regulates the structural continuity of sperm Ca(2+) signaling domains and is required for normal fertility - Elife
Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells - Elife
Frequent Zika Virus Sexual Transmission and Prolonged Viral RNA Shedding in an Immunodeficient Mouse Model - Cell Reports
Two modes of enteric gliotransmission differentially affect gut physiology - Glia
Epileptiform activity and behavioral arrests in mice overexpressing the calcium channel subunit ë±2ë«-1 - Neurobiology of Disease
Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation - PLOS ONE
Ablation of Cyclophilin D Results in an Activation of FAK, Akt and ERK Pathways in the Mouse Heart - Journal of Cellular Biochemistry
Action Potentials and Ion Conductances in Wild-type and CALHM1-knockout Type II Taste Cells - Journal of Neurophysiology
A Longitudinal Investigation into the Effect of Zn and Cu on Spatial Learning/Memory and Social Preference in a Mouse Model of LOAD - Thesis
Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model - Biochimica et Biophysica Acta
Parvalbumin Interneurons Modulate Striatal Output and Enhance Performance during Associative Learning - Neuron
Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice - Elife
Mebendazole and a non-steroidal anti-inflammatory combine to reduce tumor initiation in a colon cancer preclinical model - Oncotarget
Mertk on tumor macrophages is a therapeutic target to prevent tumor recurrence following radiation therapy - Oncotarget
Abnormal Capillary Vasodynamics Contribute to Ictal Neurodegeneration in Epilepsy - Scientific Reports
Absence of a gestational diabetes phenotype in the LepRdb/+ mouse is independent of control strain, diet, misty allele, or parity - Scientific Reports
Adrenocorticotropic hormone protects learning and memory function in epileptic Kcna1-null mice - Neuroscience Letters
An anthocyanin-enriched extract from strawberries delays disease onset and extends survival in the hSOD1(G93A) mouse model of amyotrophic lateral sclerosis - Nutritional Neuroscience
Responsiveness of Brca1 and Trp53 Deficiency-Induced Mammary Preneoplasia to Selective Estrogen Modulators versus an Aromatase Inhibitor in Mus musculus - Cancer Prevention Research (Phila)
Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice - Nature
Modulating the therapeutic response of tumours to dietary serine and glycine starvation - Nature
Phosphorylation of Rab-coupling protein by LMTK3 controls Rab14-dependent EphA2 trafficking to promote cell:cell repulsion - Nature Communications
Embryonic transcription factor expression in mice predicts medial amygdala neuronal identity and sex-specific responses to innate behavioral cues - Elife
Astrocytes modulate thalamic sensory processing via mGlu2 receptor activation - Neuropharmacology
Investigating the Role of Serotonin in Methamphetamine Psychosis: Unaltered Behavioral Effects of Chronic Methamphetamine in 5-HT1A Knockout Mice - Frontiers in Psychiatry
Embryonic Transcription Factor Expression Predicts Neuronal Identity and Innate Behavioral Activation Patterns in the Limbic System - Thesis
Protease induced plasticity: Matrix metalloproteinase-1 activation of protease activated receptor 1 induces neuronal structural plasticity - Thesis
PPARë_-pERK interaction restores memory consolidation in an Alzheimer's disease model - Thesis
Chemopreventive efficacy of curcumin-loaded PLGA microparticles in a transgenic mouse model of HER-2-positive breast cancer - Drug Delivery and Translational Research
Treadmill exercise delays the onset of non-motor behaviors and striatal pathology in the CAG140 knock-in mouse model of Huntington's disease. - Neurobiology of Disease
The role of the brown adipose tissue in ë_3-adrenergic receptor activation-induced sleep, metabolic and feeding responses - Scientific Reports
Development of an inducible mouse model of iRFP713 to track recombinase activity and tumour development in vivo - Scientific Reports
Proteomic profiling of the hypothalamus in two mouse models of narcolepsy - Proteomics
Phosphorus Taste Involves T1R2 and T1R3 - Chemical Senses
Enkephalin levels and the number of neuropeptide Y-containing interneurons in the hippocampus are decreased in female cannabinoid-receptor 1 knock-out mice - Neuroscience Letters
Targeting Tumour Angiogenesis in Colorectal Cancer Liver Metastases - Thesis
The Na(+)/Ca(2+), K(+) exchanger NCKX4 is required for efficient cone-mediated vision - Elife
Treadmill exercise delays the onset of non-motor behaviors and striatal pathology in the CAG 140 knock-in mouse model of Huntington's disease - Neurobiology of Disease
PPARgamma agonists rescue increased phosphorylation of FGF14 at S226 in the Tg2576 mouse model of Alzheimer's disease - Experimental Neurology
Role of ERë± in Mediating Female Uterine Transcriptional Responses to IGF1 - Endocrinology
Functional perturbation of forebrain principal neurons reveals differential effects in novel and well-learned tasks. - Brain Research
Skeletal Cell YAP And TAZ Redundantly Promote Bone Development By Regulation Of Collagen I Expression And Organization - bioRxiv
Mechanisms Regulating Growth Progression of Salivary Gland Neoplasms Using Mucoepidermoid Carcenoma Primary Cells - Thesis
Dopamine neuron dependent behaviors mediated by glutamate cotransmission - bioRxiv
Measuring the olfactory bulb input-output transformation reveals a contribution to the perception of odorant concentration invariance - Nature Communications
A novel humanized mouse lacking murine P450 oxidoreductase for studying human drug metabolism - Nature Communications
Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells - Molecular Biology of the Cell
Endothelium-derived fibronectin regulates neonatal vascular morphogenesis in an autocrine fashion - Angiogenesis
Monosynaptic retrograde tracing of neurons expressing the G-protein coupled receptor Gpr151 in the mouse brain - The Journal of Comparative Neurology
Tonotopic alterations in inhibitory input to the medial nucleus of the trapezoid body in a mouse model of Fragile X syndrome - The Journal of Comparative Neurology
The Neural Encoding of Reward in the Striatal-Pallidal Circuitry - Thesis
Importance of poly (A)-binding protein 4 (PABP4) in healthy pregnancy - Thesis
Systematic Identification of MCU Modulators by Orthogonal Interspecies Chemical Screening - Molecular Cell
Piezo1 channels sense whole body physical activity to reset cardiovascular homeostasis and enhance performance - Nature Communications
Gemcitabine-induced TIMP1 attenuates therapy response and promotes tumor growth and liver metastasis in pancreatic cancer - Cancer Research
The selective Tie2 inhibitor rebastinib blocks recruitment and function of Tie2Hi macrophages in breast cancer and pancreatic neuroendocrine tumors - Molecular Cancer Therapeutics
The Small Rho GTPase TC10 Modulates B Cell Immune Responses - Journal of Immunology
Detection of Maltodextrin and Its Discrimination from Sucrose are Independent of the T1R2+T1R3 Heterodimer - American Journal of Physiology
Increased ethanol drinking in humanized mice expressing the mu opioid receptor A118G polymorphism are mediated through sex-specific mechanisms - Brain Research Bulletin
Mutations in the Katnb1 gene cause left-right asymmetry and heart defects - Developmental Dynamics
Beneficial Effects of Prebiotic Saccharomyces cerevisiae Mannan on Allergic Asthma Mouse Models - Journal of Immunology Research
Morphology of Dbx1 respiratory neurons in the preB̦tzinger complex and reticular formation of neonatal mice - Scientific Data
cTag-PAPERCLIP Reveals Alternative Polyadenylation Promotes Cell-Type Specific Protein Diversity and Shifts Araf Isoforms with Microglia Activation - Neuron
Identification of HSP90 inhibitors as a novel class of senolytics - Nature Communications
Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes - Cell Reports
Rubrocerebellar feedback loop isolates the interposed nucleus as an independent processor of corollary discharge information in mice - Journal of Neuroscience
Experience-dependent synaptic plasticity in V1 occurs without microglial CX3CR1 - Journal of Neuroscience
Morphine activation of mu opioid receptors causes disinhibition of neurons in the ventral tegmental area mediated by β-arrestin2 and c-Src - Scientific Reports
Intracellular Chloride Regulation in AVP+ and VIP+ Neurons of the Suprachiasmatic Nucleus - Scientific Reports
Intravenous treatment with human recombinant ApoA-I Milano reduces beta amyloid cerebral deposition in the APP23-transgenic mouse model of Alzheimer's disease - Neurobiology of Aging
Inflammation alters AMPA-stimulated calcium responses in dorsal striatal D2 but not D1 spiny projection neurons - European Journal of Neuroscience
Pazopanib Reduces Phosphorylated Tau Levels and Alters Astrocytes in a Mouse Model of Tauopathy - Journal of Alzheimers Disease
Histone chaperone HIRA deposits histone H3. 3 onto foreign viral DNA and contributes to anti-viral intrinsic immunity - Nucleic Acids Research
Reliable sensory processing in mouse visual cortex through inhibitory interactions between Somatostatin and Parvalbumin interneurons - bioRxiv
Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes - Frontiers in Immunology
Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration. - Neuron
Endothelial jagged-2 sustains hematopoietic stem and progenitor reconstitution after myelosuppression - The Journal of Clinical Investigation‰
Dephosphorylation by protein phosphatase 2A regulates visual pigment regeneration and the dark adaptation of mammalian photoreceptors - Proceedings of the National Academy of Sciences of the United States of America
Molecular architecture underlying fluid absorption by the developing inner ear - Elife
Analysis of Nkx3.1:Cre-driven Erk5 deletion reveals a profound spinal deformity which is linked to increased osteoclast activity - Scientific Reports
Sim1 neurons are sufficient for MC4R-mediated sexual function in male mice - Endocrinology
The caspase-8/RIPK3 signaling axis in antigen presenting cells controls the inflammatory arthritic response - Arthritis Research and Therapy
Characterising the Role of mTORC1 in Myeloid Cells - Thesis
Activation of the Aryl Hydrocarbon Receptor Interferes with Early Embryonic Development - Stem Cell Reports
CXCR2-Dependent Accumulation of Tumor-Associated Neutrophils Regulates T-cell Immunity in Pancreatic Ductal Adenocarcinoma - Cancer Immunology Research
Chronic Stress Alters Striosome-Circuit Dynamics, Leading to Aberrant Decision-Making - Cell
IRF3 and type I interferons fuel a fatal response to myocardial infarction - Nature Medicine
Bim suppresses the development of SLE by limiting myeloid inflammatory responses - Journal of Experimental Medicine
Staphylococcus aureus Epicutaneous Exposure Drives Skin Inflammation via IL-36-Mediated T Cell Responses. - Cell Host Microbe
HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury - Proceedings of the National Academy of Sciences of the United States of America
Characterization of ApoJ-reconstituted high-density lipoprotein (rHDL) nanodisc for the potential treatment of cerebral β-amyloidosis - Scientific Reports
In vivo evidence that RBM5 is a tumour suppressor in the lung - Scientific Reports
Accumulation of rest deficiency precedes sudden death of epileptic Kv1.1 knockout mice, a model of sudden unexpected death in epilepsy - Epilepsia
Targeted deletion of c‐Met in thymic epithelial cells leads to an autoimmune phenotype - Immunology and Cell Biology
Brain-derived neurotrophic factor (BDNF) determines a sex difference in cue-conditioned alcohol seeking in rats. - Behavioral Brain Research
Growth Differentiation Factor 11 does not Mitigate the Lethal Effects of Total-Abdominal Irradiation - Radiation Research
Katanin-like 2 (KATNAL2) functions in multiple aspects of haploid male germ cell development in the mouse - PLOS Genetics
Testosterone replacement in transgenic sickle cell mice controls priapic activity and upregulates PDE5 expression and eNOS activity in the penis - Andrology
Mode of Surgical Injury Influences the Source of Urothelial Progenitors during Bladder Defect Repair - Stem Cell Reports
Dose-Dependent Rescue of KO Amelogenin Enamel by Transgenes in Vivo. - Frontiers in Physiology
Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents. - Nature
ERBB3 and NGFR mark a distinct skeletal muscle progenitor cell in human development and hPSCs - Nature Cell Biology
Loss of PBRM1 rescues VHL dependent replication stress to promote renal carcinogenesis - Nature Communications
CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis - Developmental Cell
STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis - Cell Reports
The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury - Journal of Immunology
Kif1bp loss in mice leads to defects in the peripheral and central nervous system and perinatal death - Scientific Reports
Neuronal CCL2 expression drives inflammatory monocyte infiltration into the brain during acute virus infection - Journal of Neuroinflammation
Fatty acid binding protein 5 mediates the uptake of fatty acids, but not drugs, into human brain endothelial cells - Journal of Pharmaceutical Sciences
The Endosomal-Lysosomal Pathway is Dysregulated by APOE4 Expression In Vivo - Frontiers in Neuroscience
HSCB, a Co-chaperone in Mitochondrial Iron-Sulfur Cluster Biogenesis, is a Novel Candidate Gene for Congenital Sideroblastic Anemia - Thesis
Single point mutation on the gene encoding dysbindin results in recognition deficits - Brain and Behavior
Consistent hypersocial behavior in mice carrying a deletion of Gtf2i but no evidence of hyposocial behavior with Gtf2i duplication: Implications for Williams–Beuren syndrome and autism spectrum disorder - Brain and Behavior
Bimodal RMS distributions for the objective detection of theta (θ) and gamma (γ) brain oscillations during long-term continuous LFP recordings in mice - MACRo 2015
Cholangiocytes act as facultative liver stem cells during impaired hepatocyte regeneration - Nature
Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors - Proceedings of the National Academy of Sciences of the United States of America
Targeting multiple effector pathways in pancreatic ductal adenocarcinoma with a G-quadruplex-binding small molecule - Journal of Medicinal Chemistry
Neurogenesis during abstinence is necessary for context-driven methamphetamine-related memory - Journal of Neuroscience
Skeletal cell YAP and TAZ combinatorially promote bone development - The FASEB Journal
Respiratory dysfunction progresses with age in Kcna1-null mice, a model of sudden unexpected death in epilepsy - Epilepsia
Transcriptomic analysis of gene signatures associated with sickle pain - Scientific Data
The large-conductance voltage- and Ca2+ -activated K+ channel and its γ1 subunit modulate mouse uterine artery function during pregnancy - Journal of Physiology (London)
Oxytocin and the warm outer glow: Thermoregulatory deficits cause huddling abnormalities in oxytocin-deficient mouse pups - Hormones and Behavior
Pazopanib Reduces Tau Pathology and Restores Astrocytes in a Novel Mouse Model of Neurodegenerative Tauopathy - Thesis
A Braf kinase-inactive mutant induces lung adenocarcinoma - Nature
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity - Nature Medicine
Delayed Degradation and Impaired Dendritic Delivery of Intron-LackingEGFP-Arc/Arg3.1mRNA inEGFP-ArcTransgenic Mice - Frontiers in Molecular Neuroscience
The Bcl-2 Homology-3 Domain (BH3)-Only Proteins, Bid, DP5/Hrk, and BNip3L, Are Upregulated in Reactive Astrocytes of End-Stage Mutant SOD1 Mouse Spinal Cord - Frontiers in Cellular Neuroscience
The Complement System Is Critical in Maintaining Retinal Integrity during Aging - Frontiers in Aging Neuroscience
Water transport and homeostasis as a major function of erythrocytes - American Journal of Physiology Heart and Circulatory Physiology
Taste sensitivity to a mixture of monosodium glutamate and inosine 5'-monophosphate by mice lacking both subunits of the T1R1+T1R3 amino acid receptor - American Journal of Physiology Regulatory, Integrative and Comparative Physiology
Gain-of-function and dominant-negative effects of distinct p53 mutations in lung tumours - Thesis
Development of T cell based therapeutic strategies for childhood cancer neuroblastoma - Thesis
INSL5 activates multiple signalling pathways and regulates GLP-1 secretion in NCI-H716 cells - Journal of Molecular Endocrinology
Evidence of Wnt/β-Catenin alterations in brain and bone of a tauopathy mouse model of Alzheimer’s disease - Neurobiology of Aging
The vulnerability of spinal motoneurons and soma size plasticity in a mouse model of amyotrophic lateral sclerosis - The Journal of Physiology
Paracrine cellular senescence exacerbates biliary injury and impairs regeneration - Nature Communications
Dopamine D2 Receptors in Dopaminergic Neurons Modulate Performance in a Reversal Learning Task in Mice - eNeuro
Consistent hypersocial behavior in mice carrying a deletion ofGtf2ibut no evidence of hyposocial behavior withGtf2iduplication: Implications for Williams-Beuren syndrome and autism spectrum disorder - Brain and Behavior
Characteristics of cellular and synaptic function in rodent forebrain neurons with altered SynGAP expression - Thesis
Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay - Proceedings of the National Academy of Sciences of the United States of America
Sprouty2 loss-induced IL6 drives castration-resistant prostate cancer through scavenger receptor B1 - EMBO Molecular Medicine
Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer's disease - Molecular Neurodegeneration
PI3Kδ hyper-activation promotes the development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner - bioRxiv
Phospho-regulation of Atoh1 is required for plasticity of secretory progenitors and tissue regeneration - bioRxiv
Impact of X/Y genes and sex hormones on mouse neuroanatomy - Neuroimage
Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells - Cancer Cell
An Autoimmune Basis for Raynaud's Phenomenon: Murine Model and Human Disease - Arthritis &amp; Rheumatology
Evidence of Wnt/β-catenin alterations in brain and bone of a tauopathy mouse model of Alzheimer's disease - Neurobiology of Aging
Activity-dependent modulation of hippocampal synaptic plasticity via PirB and endocannabinoids - Molecular Psychiatry
Galectins Control mTOR in Response to Endomembrane Damage - Molecular Cell
The ERBB network facilitates KRAS-driven lung tumorigenesis - bioRxiv
SOX11 augments BCR signaling to drive MCL-like tumor development - Blood
The role of CX3CR1 in pancreatic cancer - Thesis
CALHM3 Is Essential for Rapid Ion Channel-Mediated Purinergic Neurotransmission of GPCR-Mediated Tastes - Neuron
Type-2 diabetic aldehyde dehydrogenase 2 mutant mice (ALDH 2*2) exhibiting heart failure with preserved ejection fraction phenotype can be determined by exercise stress echocardiography - PLOS ONE
Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging - Redox Biology
Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M - Nature Communications
The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia - Cell Metabolism
Studies of Breast Cancer Chemoprevention in Human High-risk Primary Cells and Genetically Engineered Mouse Models - Thesis
Abnormal Sleep Architecture and Hippocampal Circuit Dysfunction in a Mouse Model of Fragile X Syndrome - Neuroscience
CSF1R+ Macrophages Sustain Pancreatic Tumor Growth through T Cell Suppression and Maintenance of Key Gene Programs that Define the Squamous Subtype - Cell Reports
Role of Enteric Glial Activation in Gastrointestinal Physiology and Inflammation - Thesis
Global Untargeted Serum Metabolomic Analyses Nominate Metabolic Pathways Responsive to Loss of Expression of the Orphan Metallo β-Lactamase, Mblac1 - Molecular Omics
MiR-142-3p is downregulated in aggressive p53 mutant mouse models of pancreatic ductal adenocarcinoma by hypermethylation of its locus - Cell Death and Disease
Chemogenetic Enhancement of Axon Regeneration Following Peripheral Nerve Injury in the SLICK-A Mouse - Brain Sciences
Identification of Correlative Shifts in Indices of Brain Cholesterol Metabolism in the C57BL6/Mecp2tm1.1Bird Mouse, a Model for Rett Syndrome - Lipids
Spontaneous Hair Cell Regeneration Is Prevented by Increased Notch Signaling in Supporting Cells - Frontiers in Cellular Neuroscience
Membrane Mucin Muc4 promotes blood cell association with tumor cells and mediates efficient metastasis in a mouse model of breast cancer - Oncogene
Separate functional properties of NMDARs regulate distinct aspects of spatial cognition - Learning &amp; Memory
RNaseT2 knockout rats exhibit hippocampal neuropathology and deficits in memory - Disease Models and Mechanisms
Brown adipose tissue plays a central role in systemic inflammation-induced sleep responses - PLOS ONE
Cell-Type-Specific Role of ΔFosB in Nucleus Accumbens In Modulating Intermale Aggression - The Journal of Neuroscience
A Combination of Ontogeny and CNS Environment Establishes Microglial Identity - Neuron
TectaY1870C/+ mice with alterations in the structure and porosity of the tectorial membrane display large numbers of spontaneous emissions - AIP Conference Proceedings
The Biochemical Effects of Tau and Zinc in A Tau Mouse Model - Thesis
Zinc Exacerbates Tau Pathology in a Tau Mouse Model - Journal of Alzheimers Disease
Effects of living at moderate altitude on pulmonary vascular function and exercise capacity in mice with sickle cell anemia - The Journal of Physiology
Hydroxyurea embryotoxicity is enhanced in P53-deficient mice - Reproductive Toxicology
Functional cross-talk between PTEN and PDK1 in normal haematopoiesis and leukaemia development - Thesis
Investigating the role of thiosulfate sulfurtransferase in adipose tissue dysfunction in obesity - Thesis
A novel sialylation site on Neisseria gonorrhoeae lipooligosaccharide links heptose II lactose expression with pathogenicity - Infection and Immunity
Impairing hepatocyte regeneration to determine the regenerative capacity of the biliary epithelium - Thesis
Iron Chelation with Transdermal Deferoxamine Accelerates Healing of Murine Sickle Cell Ulcers - Advances in Wound Care
POT1a depletion in the developing brain leads to p53-dependent neuronal cell death and ataxia. - bioRxiv
TSPO-PET Imaging Using [18F]PBR06 is a Potential Translatable Biomarker for Treatment Response in Huntington's Disease: Preclinical Evidence with the p75NTR Ligand LM11A-31 - Human Molecular Genetics
Characterization of Adult Vestibular Organs in 11 CreER Mouse Lines - Journal of the Association for Research in Otolaryngology (JARO)
Targeted deletion of c-Met in thymic epithelial cells leads to an autoimmune phenotype - Immunology and Cell Biology
Temporal changes in macrophage phenotype after peripheral nerve injury - Journal of Neuroinflammation
Differential electrophysiological properties of D1 and D2 spiny projection neurons in the mouse nucleus accumbens core - Physiological Reports
Constitutive and Conditional Deletion of Type 1 Dopamine Receptor (Drd1) to Study Food Anticipatory Activity - Thesis
Alterations of functional circuitry in aging brain and the impact of mutated APP expression - Neurobiology of Aging
Triheteromeric GluN1/GluN2A/GluN2C NMDARs with Unique Single-Channel Properties Are the Dominant Receptor Population in Cerebellar Granule Cells - Neuron
Synaptic vesicle recycling in preclinical models of intellectual disability, autism spectrum disorder and epilepsy - Thesis
Tropomyosin 3.5 protects F-actin networks required for tissue biomechanical properties - bioRxiv
Persistent Infiltration and Impaired Response of Peripherally-Derived Monocytes after Traumatic Brain Injury in the Aged Brain - International Journal of Molecular Sciences
Effects of 5-HT1A Receptor Agonism on Repetitive Grooming and Learning Behavior in Shank3B Mice - Thesis
Contractile functions of Piezo1 channels in murine arteries - Thesis
GAL3 receptor knockout mice exhibit an alcohol-preferring phenotype - Addiction Biology
Suppression of Harmaline Tremor by Activation of an Extrasynaptic GABAA Receptor: Implications for Essential Tremor - Tremor and Other Hyperkinetic Movements
Disruption of the Zdhhc9 intellectual disability gene leads to behavioural abnormalities in a mouse model - Experimental Neurology
Citrullinated histone 3 causes endothelial barrier dysfunction - Biochemical and Biophysical Research Communications
53BP1-RIF1-shieldin counteracts DSB resection through CST- and Polα-dependent fill-in - Nature
Loss of maternal EED results in postnatal overgrowth - Clinical Epigenetics
The role of Runx1 in genetic models of breast cancer - Thesis
This is to certify that the work contained within has been composed by me and is entirely my own work. No part of this thesis has been submitted for any other - Thesis
Pathway specific drive of cerebellar Golgi cells reveals integrative rules of cortical inhibition - bioRxiv
Depletion of haptoglobin and hemopexin promote hemoglobin-mediated lipoprotein oxidation in sickle cell disease - American Journal of Physiology
Inhibiting autophagy reduces retinal degeneration caused by protein misfolding - Autophagy
CTCF maintains regulatory homeostasis of cancer pathways - Genome Biology
Astrocytes and neurons produce distinct types of polyglucosan bodies in Lafora disease - Glia
MYBL2 supports DNA double strand break repair in haematopoietic stem cells - Cancer Research
An Examination of the Role of L-Glutamate and Inosine 5'-Monophosphate in Hedonic Taste-Guided Behavior by Mice Lacking the T1R1 + T1R3 Receptor - Chemical Senses
Communication Between Enteric Neurons, Glia, and Nociceptors Underlies the Effects of Tachykinins on Neuroinflammation - Cellular and Molecular Gastroenterology and Hepatology
GPR55 signalling promotes proliferation of pancreatic cancer cells and tumour growth in mice, and its inhibition increases effects of gemcitabine - Oncogene
Intestine-specific expression of human chimeric intestinal alkaline phosphatase attenuates Western diet-induced barrier dysfunction and glucose intolerance - Physiological Reports
Distinct Bone Marrow Sources of Pleiotrophin Control Hematopoietic Stem Cell Maintenance and Regeneration - Stem Cells
Mapping Transgene Insertion Sites Reveals Complex Interactions Between Mouse Transgenes And Neighboring Endogenous Genes - bioRxiv
Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration - Cell Reports
Exacerbation of dystrophic cardiomyopathy by phospholamban deficiency-mediated chronically increased cardiac Ca2+ cycling in vivo - American Journal of Physiology
Ndr kinases regulate retinal interneuron proliferation and homeostasis - Scientific Reports
One-step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock-in mice - The EMBO Journal
Apigenin Inhibits UVB-Induced Skin Carcinogenesis: The Role of Thrombospondin-1 as an Anti-Inflammatory Factor - Neoplasia
Loss of MST/Hippo signaling in a genetically engineered mouse model of fusion-positive rhabdomyosarcoma accelerates tumorigenesis - Cancer Research
A Dominant Role for the Beta 4 Nicotinic Receptor Subunit in Nicotinic Modulation of Glomerular Microcircuits in the Mouse Olfactory Bulb - Journal of Neurophysiology
PI3Kδ hyper-activation promotes development of B cells that exacerbate Streptococcus pneumoniae infection in an antibody-independent manner - Nature Communications
Prestin Contributes to Membrane Compartmentalization and Is Required for Normal Innervation of Outer Hair Cells - Frontiers in Cellular Neuroscience
Fine-Tuning Mybl2 Is Required for Proper Mesenchymal-to-Epithelial Transition during Somatic Reprogramming - Cell Reports
Deficiency of the Endocytic Protein Hip1 Leads to Decreased Gdpd3 expression, Low Phosphocholine, and Kypholordosis - bioRxiv
Knock-in rats expressing Cre and Flp recombinases at the Parvalbumin locus. - bioRxiv
Whole genomes redefine the mutational landscape of pancreatic cancer - Nature
Chronic GLP-1 receptor activation by exendin-4 induces expansion of pancreatic duct glands in rats and accelerates formation of dysplastic lesions and chronic pancreatitis in the Kras(G12D) mouse model - Diabetes
Lhx1 controls terminal differentiation and circadian function of the suprachiasmatic nucleus - Cell Reports
Sialylation regulates brain structure and function - FASEB Journal
Trp63 is regulated by STAT5 in mammary tissue and subject to differentiation in cancer - Endocrine Related Cancer
Beneficial Effect of the Nitric Oxide Donor Compound 3-(1,3-Dioxoisoindolin-2-yl)Benzyl Nitrate on Dysregulated Phosphodiesterase 5, NADPH Oxidase, and Nitrosative Stress in the Sickle Cell Mouse Penis: Implication for Priapism Treatment - Journal of Pharmacology and Expreimental Therapeutics
Sex-specific regulation of weight and puberty by the Lin28/let-7 axis - Journal of Endocrinology
Isoaspartyl formation in creatine kinase B is associated with loss of enzymatic activity; implications for the linkage of isoaspartate accumulation and neurological dysfunction in the PIMT knockout mouse - PLOS ONE
Corrigendum to Enkephalin levels and the number of neuropeptide Y-containing interneurons in the hippocampus are decreased in female cannabinoid-receptor 1 knock-out mice [Neurosci. Lett. 620 (2016) 97-103] - Neuroscience Letters
Investigating the Production of Auto-Antibodies at Different Stages of B Cell Development - Thesis
Targeted lentiviral-mediated delivery of progranulin cDNA in a genetic model of amyotrophic lateral sclerosis - Thesis
Hippocampal neural progenitor cells play a distinct role in fear memory retrieval in male and female CIE rats - Neuropharmacology
Metabolic and vascular effects of thiosulfate sulfurtransferase deletion - Thesis
Ketogenic diet regulates the antioxidant catalase via the transcription factor PPAR?2 - Epilepsy Res.
Examining the Role of Cone-expressed RPE65 in Mouse Cone Function - Sci Rep
Increased tau phosphorylation follows impeded dopamine clearance in a P301L and novel P301L/COMT-deleted (DM) tau mouse model - J. Neurochem.
Inhibition of Atypical Protein Kinase C Reduces Inflammation-Induced Retinal Vascular Permeability - Am. J. Pathol.
Cre-dependent optogenetic transgenic mice without early age-related hearing loss - bioRxiv
Precision medicine approach: Empagliflozin for diabetic cardiomyopathy in mice with aldehyde dehydrogenase (ALDH) 2?2 mutation, a specific genetic mutation in millions of East Asians - Eur. J. Pharmacol.
The EGF-LIKE domain of thrombospondin-4 is a key determinant in the development of pain states due to increased excitatory synaptogenesis - J. Biol. Chem.
GIRK currents in VTA dopamine neurons control the sensitivity of mice to cocaine-induced locomotor sensitization - Proc. Natl. Acad. Sci. U.S.A.
Mouse Models of Pain in Sickle Cell Disease - Curr Protoc Neurosci
Reduced PRC2 function alters male germline epigenetic programming and paternal inheritance - BMC Biol.
Sex differences in vocal communication of freely interacting adult mice depend upon behavioral context - PLOS ONE
The susceptibility of cochlear outer hair cells to cyclodextrin is not related to their electromotile activity - Acta Neuropathol Commun
Astrocyte-Secreted Chordin-like 1 Drives Synapse Maturation and Limits Plasticity by Increasing Synaptic GluA2 AMPA Receptors - Neuron
Impaired innate immune signaling due to combined Toll-like receptor 2 and 4 deficiency affects both periodontitis and atherosclerosis in response to polybacterial infection - Pathog Dis
Estudio de variantes estructurales de ApoA-I y ApoJ recombinantes como aproximación terapéutica en el contexto de la ß-amiloidosis cerebral - Thesis
Sex-Dependent Effects of Environmental Enrichment on Spatial Memory and Brain-Derived Neurotrophic Factor (BDNF) Signaling in a Developmental "Two-Hit" Mouse Model Combining BDNF Haploinsufficiency and Chronic Glucocorticoid Stimulation - Front Behav Neurosci
Loss of amphiregulin reduces myoepithelial cell coverage of mammary ducts and alters breast tumor growth - Breast Cancer Res.
Injury promotes sarcoma development in a genetically and temporally restricted manner - JCI Insight
Investigating the Ca2+-dependent and Ca2+-independent mechanisms for mammalian cone light adaptation - Sci Rep
Genetic and behavioural requirements for structural brain plasticity - bioRxiv
Fisetin is a senotherapeutic that extends health and lifespan - EBioMedicine
Early functional connectivity deficits and progressive microstructural alterations in the TgF344-AD rat model of Alzheimer's Disease: A longitudinal MRI study - Neurobiol. Dis.
NCLX prevents cell death during adrenergic activation of the brown adipose tissue - bioRxiv
Leukemia development initiated by deletion of RBP-J: mouse strain, deletion efficiency, and cell of origin - Dis Model Mech
The HDAC3-SMARCA4-miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma - Sci Signal
Placental Macrophages: A Window Into Fetal Microglial Function in Maternal Obesity - Int. J. Dev. Neurosci.
Early impacts of modified food consistency on oromotor outcomes in mouse models of Down syndrome - Physiol. Behav.
Macrophage Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer - bioRxiv
Diet-Induced Insulin Resistance Elevates Hippocampal Glutamate as well as VGLUT1 and GFAP Expression in AßPP/PS1 Mice - J. Neurochem.
NLRP3 Promotes Diabetic Bladder Dysfunction and Changes in Symptom-Specific Bladder Innervation - Diabetes
Foxc2 is required for proper cardiac neural crest cell migration, outflow tract septation, and ventricle expansion - Dev. Dyn.
Direct intracellular signaling by the carboxy terminus of NMDA receptor GluN2 subunits regulates dendritic morphology in hippocampal CA1 pyramidal neurons - Neuroscience
Investigating the Role of the Growth Hormone Secretagogue Receptor in Food-Motivated Behaviours - Thesis
Increased susceptibility to cortical spreading depression and epileptiform activity in a mouse model for FHM2 - Sci Rep
Establishing sleep stages using Delta, Theta and Gamma oscillations from long term Local Field Potential (LFP) recordings in mice - researchgate.net
Knock-in rat lines with Cre recombinase at the dopamine D1 and adenosine 2a receptor loci. - bioRxiv
Phenotypic Modulation of Skeletal Muscle Fibers in LPIN1-Deficient Lipodystrophic ( fld) Mice - Vet. Pathol.
CHARACTERIZING AQP9: A REGULATOR OF EPIPHYSEAL PLATE CHONDROCYTE PROLIFERATION, HYPERTROPHY, AND LONG BONE GROWTH - Thesis
1-(4-nitrobenzenesulfonyl)-4-penylpiperazine increases the number of Peyer’s patch-associated regenerating crypts in the small intestines after radiation injury - Radiotherapy and Oncology
Improving Outcomes in NF1 Spine Fusion - Thesis
Arkadia degrades SNON to activate level-specific NODAL responses - bioRxiv
Salmonella Persist in Activated Macrophages in T Cell-Sparse Granulomas but Are Contained by Surrounding CXCR3 Ligand-Positioned Th1 Cells - Immunity
Multiple receptors converge on H2-Q10 to regulate NK &amp; γδT cell development - Immunology and Cell Biology
Early Life Stress Drives Sex-Selective Impairment in Reversal Learning by Affecting Parvalbumin Interneurons in Orbitofrontal Cortex of Mice - Cell Rep
Sox9 regulates cell state and activity of embryonic mouse mammary progenitor cells - Communications Biology
A Novel hAPP/htau Mouse Model of Alzheimer's Disease: Inclusion of APP With Tau Exacerbates Behavioral Deficits and Zinc Administration Heightens Tangle Pathology - Front Aging Neuroscience
Sex- and Development-Dependent Responses of Rat Microglia to Pro- and Anti-inflammatory Stimulation - Front Cell Neuroscience
The Effect of Maternal Obesity on Placental Cell-Free DNA Release in a Mouse Model - Reproductive Sciences
Sudden heart rate reduction upon optogenetic release of acetylcholine from cardiac parasympathetic neurons in perfused hearts - bioRxiv
A sensorimotor pathway via higher-order thalamus - Journal of Neuroscience
Harnessing Genetic Complexity to Enhance Translatability of Alzheimer's Disease Mouse Models: A Path toward Precision Medicine - Neuron
The α7 nicotinic acetylcholine receptors regulate hippocampal adult-neurogenesis in a sexually dimorphic fashion - Brain Structure and Function
Cellular interactions underpinning the immunomodulatory action of mesenchymal stromal cells in models of liver transplant injury - Thesis
LCAT Enzyme Replacement Therapy Reduces LpX and Improves Kidney Function in a Mouse Model of Familial LCAT Deficiency - Journal of Pharmacology and Experimental Therapeutics
SETD3 is an actin histidine methyltransferase that prevents primary dystocia - Nature