Category: Proceedings of the National Academy of Sciences of the United States of America

 

Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Nguyen, AD;Nguyen, TA;Zhang, J;Devireddy, S;Zhou, P;Karydas, AM;Xu, X;Miller, BL;Rigo, F;Ferguson, SM;Huang, EJ;Walther, TC;Farese, RV;

Year: 2018

Publication ID: 29511098

Publication Date: 3/20/18

Country: United States

Affiliation: Department of Genetics and Complex Diseases, Harvard T. H. Chan School of Public Health, Boston, MA 02115

Article Link
 

Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Djurec, M;Graña, O;Lee, A;Troulé, K;Espinet, E;Cabras, L;Navas, C;Blasco, MT;Martín-Díaz, L;Burdiel, M;Li, J;Liu, Z;Vallespinós, M;Sanchez-Bueno, F;Sprick, MR;Trumpp, A;Sainz, B;Al-Shahrour, F;Rabadan, R;Guerra, C;Barbacid, M;

Year: 2018

Publication ID: 29351990

Publication Date: 1/19/18

Country: Spain

Affiliation: Molecular Oncology, Centro Nacional de Investigaciones Oncológicas (CNIO), 28029 Madrid, Spain

Article Link
 

HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Magnani, ND;Dada, LA;Queisser, MA;Brazee, PL;Welch, LC;Anekalla, KR;Zhou, G;Vagin, O;Misharin, AV;Budinger, GRS;Iwai, K;Ciechanover, AJ;Sznajder, JI;

Year: 2017

Publication ID: 29109255

Publication Date: 11/21/17

Country: Israel

Affiliation: Rappaport Faculty of Medicine and Research Institute, Technion Integrated Cancer Center, Haifa, Israel 3109601

Article Link
 

Dephosphorylation by protein phosphatase 2A regulates visual pigment regeneration and the dark adaptation of mammalian photoreceptors

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Kolesnikov, AV;Orban, T;Jin, H;Brooks, C;Hofmann, L;Dong, Z;Sokolov, M;Palczewski, K;Kefalov, VJ;

Year: 2017

Publication ID: 29078372

Publication Date: 10/23/17

Country: United States

Affiliation: Department of Pharmacology, Case Western Reserve University, Cleveland, OH 44106

Article Link
 

Cystic fibrosis transmembrane conductance regulator with a shortened R domain rescues the intestinal phenotype of CFTR-/- mice

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Ostedgaard, LS;Meyerholz, DK;Vermeer, DW;Karp, PH;Schneider, L;Sigmund, CD;Welsh, MJ;

Year: 2011

Publication ID: 21285372

Publication Date: 2/15/11

Country: United States

Affiliation: Department of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA

Article Link
 

The preproghrelin gene is required for the normal integration of thermoregulation and sleep in mice

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Szentirmai, E;KapÌÁs, L;Sun, Y;Smith, RG;Krueger, JM;

Year: 2009

Publication ID: 19666521

Publication Date: 8/18/09

Country: United States

Affiliation: Sleep and Performance Research Center, Department of Veterinary and Comparative Anatomy, Pharmacology, and Physiology, Washington State University, Pullman, WA 99164, USA

Article Link
 

A human IL10 BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Ranatunga, D;Hedrich, CM;Wang, F;McVicar, DW;Nowak, N;Joshi, T;Feigenbaum, L;Grant, LR;StÌ_ger, S;Bream, JH;

Year: 2009

Publication ID: 19805095

Publication Date: 10/1/09

Country: United States

Affiliation: W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205-1901, USA

Article Link
 

CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Zhu, JG;Ochalek, JT;Kaufmann, M;Jones, G;Deluca, HF;

Year: 2013

Publication ID: 24019477

Publication Date: 9/24/13

Country: United States

Affiliation: Department of Biochemistry, University of Wisconsin, Madison, WI 53706

Article Link
 

STING manifests self DNA-dependent inflammatory disease

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Ahn, J;Gutman, D;Saijo, S;Barber, GN;

Year: 2012

Publication ID: 23132945

Publication Date: 11/20/12

Country: United States

Affiliation: Department of Cell Biology and Sylvester Comprehensive Cancer Center, University of Miami School of Medicine, Miami, FL 33136, USA

Article Link
 

Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Laposa, RR;Huang, EJ;Cleaver, JE;

Year: 2007

Publication ID: 17229834

Publication Date: 1/23/07

Country: United States

Affiliation: Department of Dermatology and Cancer Center, University of California, San Francisco, CA 94143-0808, USA

Article Link
 

Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Ramsey, IS;Ruchti, E;Kaczmarek, JS;Clapham, DE;

Year: 2009

Publication ID: 19372380

Publication Date: 5/1/09

Country: United States

Affiliation: Howard Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, and Department of Cardiovascular Research, Manton Center for Orphan Disease, Children's Hospital, 320 Longwood Avenue, Boston, MA 02115, USA

Article Link
 

Sleeping Beauty screen reveals Pparg activation in metastatic prostate cancer

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Ahmad, I;Mui, E;Galbraith, L;Patel, R;Tan, EH;Salji, M;Rust, AG;Repiscak, P;Hedley, A;Markert, E;Loveridge, C;van der Weyden, L;Edwards, J;Sansom, OJ;Adams, DJ;Leung, HY;

Year: 2016

Publication ID: 27357679

Publication Date: 7/19/16

Country: United Kingdom

Affiliation: Cancer Research UK Beatson Institute, Bearsden, Glasgow G61 1BD, United Kingdom; Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1QH, United Kingdom; h.leung@beatson.gla.ac.uk

Article Link
 

TRPC6 channel translocation into phagosomal membrane augments phagosomal function

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Riazanski, V;Gabdoulkhakova, AG;Boynton, LS;Eguchi, RR;Deriy, LV;Hogarth, DK;LoaÌÇc, N;Oumata, N;Galons, H;Brown, ME;Shevchenko, P;Gallan, AJ;Yoo, SG;Naren, AP;Villereal, ML;Beacham, DW;Bindokas, VP;Birnbaumer, L;Meijer, L;Nelson, DJ;

Year: 2015

Publication ID: 26604306

Publication Date: 11/24/15

Country: United States

Affiliation: Laboratory of Neurobiology, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709 nelson@uchicago.edu

Article Link
 

Notch3 drives development and progression of cholangiocarcinoma

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Guest, RV;Boulter, L;Dwyer, BJ;Kendall, TJ;Man, TY;Minnis-Lyons, SE;Lu, WY;Robson, AJ;Gonzalez, SF;Raven, A;Wojtacha, D;Morton, JP;Komuta, M;Roskams, T;Wigmore, SJ;Sansom, OJ;Forbes, SJ;

Year: 2016

Publication ID: 27791012

Publication Date: 10/25/16

Country: United Kingdom

Affiliation: Medical Research Council Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4UU, United Kingdom; Department of Surgery, Royal Infirmary of Edinburgh, Edinburgh EH16 4SA, United Kingdom; stuart.forbes@ed.ac.uk

Article Link
 

Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Sah, R;Mesirca, P;Van den Boogert, M;Rosen, J;Mably, J;Mangoni, ME;Clapham, DE;

Year: 2013

Publication ID: 23878236

Publication Date: 8/1/13

Country: United States

Affiliation: Howard Hughes Medical Institute, Department of Cardiology, Boston Children's Hospital, Boston, MA 02115, USA

Article Link
 

HER2 overcomes PTEN (loss)-induced senescence to cause aggressive prostate cancer

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Ahmad, I;Patel, R;Singh, LB;Nixon, C;Seywright, M;Barnetson, RJ;Brunton, VG;Muller, WJ;Edwards, J;Sansom, OJ;Leung, HY;

Year: 2011

Publication ID: 21930937

Publication Date: 9/27/11

Country: United Kingdom

Affiliation: Beatson Institute for Cancer Research, Glasgow G61 1BD, United Kingdom

Article Link
 

Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Castillo, EF;Dekonenko, A;Arko-Mensah, J;Mandell, MA;Dupont, N;Jiang, S;Delgado-Vargas, M;Timmins, GS;Bhattacharya, D;Yang, H;Hutt, J;Lyons, CR;Dobos, KM;Deretic, V;

Year: 2012

Publication ID: 23093667

Publication Date: 11/13/12

Country: United States

Affiliation: Department of Molecular Genetics and Microbiology, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA

Article Link
 

Striosome-dendron bouquets highlight a unique striatonigral circuit targeting dopamine-containing neurons

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Crittenden, JR;Tillberg, PW;Riad, MH;Shima, Y;Gerfen, CR;Curry, J;Housman, DE;Nelson, SB;Boyden, ES;Graybiel, AM;

Year: 2016

Publication ID: 27647894

Publication Date: 10/4/16

Country: United States

Affiliation: McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA 02139; Department of Brain and Cognitive Sciences, Massachusetts Institute of Technology, Cambridge, MA 02139

Article Link
 

Identification of cancer initiating cells in K-Ras driven lung adenocarcinoma

 

Journal: Proceedings of the National Academy of Sciences of the United States of America

Authors: Mainardi, S;Mijimolle, N;Francoz, S;Vicente-Due̱as, C;SÌÁnchez-GarcÌ_a, I;Barbacid, M;

Year: 2014

Publication ID: 24367082

Publication Date: 1/1/14

Country: Spain

Affiliation: Molecular Oncology Programme, Centro Nacional de Investigaciones OncolÌ_gicas, 28029 Madrid, Spain

Article Link

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