Category: Molecular Neurodegeneration

 

Early long-term administration of the CSF1R inhibitor PLX3397 ablates microglia and reduces accumulation of intraneuronal amyloid, neuritic plaque deposition and pre-fibrillar oligomers in 5XFAD mouse model of Alzheimer’s disease

 

Journal: Molecular Neurodegeneration

Authors: Sosna, J;Philipp, S;Albay, R;Reyes-Ruiz, JM;Baglietto-Vargas, D;LaFerla, FM;Glabe, CG;

Year: 2018

Publication ID: 29490706

Publication Date: 3/1/18

Country: United States

Affiliation: Department of Molecular Biology and Biochemistry, University of California, Irvine, USA

Article Link
 

Microglial p38ë± MAPK is critical for LPS-induced neuron degeneration, through a mechanism involving TNFë±

 

Journal: Molecular Neurodegeneration

Authors: Xing, B;Bachstetter, AD;Van Eldik, LJ;

Year: 2011

Publication ID: 22185458

Publication Date: 12/20/11

Country: United States

Affiliation: Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA

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