Category: EMBO Molecular Medicine

 

Sprouty2 loss-induced IL6 drives castration-resistant prostate cancer through scavenger receptor B1

 

Journal: EMBO Molecular Medicine

Authors: Patel, R;Fleming, J;Mui, E;Loveridge, C;Repiscak, P;Blomme, A;Harle, V;Salji, M;Ahmad, I;Teo, K;Hamdy, FC;Hedley, A;van den Broek, N;Mackay, G;Edwards, J;Sansom, OJ;Leung, HY;

Year: 2018

Publication ID: 29540470

Publication Date: 3/14/18

Country: United Kingdom

Affiliation: Cancer Research UK Beatson Institute, Glasgow, UK

Article Link
 

Targeting the LOX/hypoxia axis reverses many of the features that make pancreatic cancer deadly: inhibition of LOX abrogates metastasis and enhances drug efficacy

 

Journal: EMBO Molecular Medicine

Authors: Miller, BW;Morton, JP;Pinese, M;Saturno, G;Jamieson, NB;McGhee, E;Timpson, P;Leach, J;McGarry, L;Shanks, E;Bailey, P;Chang, D;Oien, K;Karim, S;Au, A;Steele, C;Carter, CR;McKay, C;Anderson, K;Evans, TR;Marais, R;Springer, C;Biankin, A;Erler, JT;Sansom, OJ;

Year: 2015

Publication ID: 26077591

Publication Date: 6/15/15

Country: Denmark

Affiliation: Biotech Research & Innovation Centre (BRIC), University of Copenhagen, Copenhagen (UCPH), Denmark o.sansom@beatson.gla.ac.uk

Article Link
 

SPRY2 loss enhances ErbB trafficking and PI3K/AKT signalling to drive human and mouse prostate carcinogenesis

 

Journal: EMBO Molecular Medicine

Authors: Gao, M;Patel, R;Ahmad, I;Fleming, J;Edwards, J;McCracken, S;Sahadevan, K;Seywright, M;Norman, J;Sansom, O;Leung, HY;

Year: 2012

Publication ID: 22649008

Publication Date: 8/1/12

Country: United Kingdom

Affiliation: Beatson Institute for Cancer Research, Glasgow, UK

Article Link
 

p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium

 

Journal: EMBO Molecular Medicine

Authors: Cole, AM;Ridgway, RA;Derkits, SE;Parry, L;Barker, N;Clevers, H;Clarke, AR;Sansom, OJ;

Year: 2010

Publication ID: 20976827

Publication Date: 11/1/10

Country: United Kingdom

Affiliation: Beatson Institute of Cancer Research, Glasgow, UK

Article Link

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