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Referenced Publications

Overview
Founded in 2000, Transnetyx is a molecular diagnostics company based in Memphis, Tennessee that has built world’s first fully automated genotyping system for Transgenic, Knockout and Knock in mouse lines.

Process
Transnetyx uses real time PCR for genotyping.  If you would like more information regarding our process please contact us at customerservice@transnetyx.com
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Transnetyx has been referenced in the following publications.
 
 Date  Publication  Summary  View
June 2013 SciVerse Effects of stimulus salience on touchscreen serial reversal learning in a mouse model of fragile X syndrome Click Here
May 2013 Cell RAS and RHO Families of GTPases Directly Regulate Distinct Phosphoinositide 3-Kinase Isoforms Click Here
May 2013 PLOS One Cholecystokinin: An Excitatory Modulator of Mitral/Tufted Cells in the Mouse Olfactory Bulb
 
Click Here
May 2013 SciVerse Maneb causes pro-oxidant effects in the hippocampus of Nrf2 knockout mice Click Here
May 2013 American Journal of Pathology The PPARγ Agonist Efatutazone Increases the Spectrum of Well-Differentiated Mammary Cancer Subtypes Initiated by Loss of Full-Length BRCA1 in Association with TP53 Haploinsufficiency Click Here
May 2013 University of Glasgow Fascin 1 is transiently expressed in mouse melanoblasts during development and promotes migration and proliferation Click Here
Apr 2013 Physiology Journal Altered Responses to Cold Environment in Urocortin 1 and Corticotropin-Releasing Factor Deficient Mice Click Here
Apr 2013 Journal of Neuroscience Homeostatic Responses Fail to Correct Defective Amygdala Inhibitory Circuit Maturation in Fragile X Syndrome Click Here
Apr 2013 Virology Journal ZASC1 knockout mice exhibit an early bone marrow-specific defect in murine leukemia virus replication Click Here
Apr 2013 Wiley Online Library Chk1 is essential for the development of murine epidermal melanocytes Click Here
Arp 2013 The Journal of Neuroscience The p38α MAPK Regulates Microglial Responsiveness to Diffuse Traumatic Brain Injury Click Here
Mar 2013 SciVerse Hijacking the Neuronal NMDAR Signaling Circuit to Promote Tumor Growth and Invasion Click Here
Mar 2013 APS Nitric Oxide reduces Cl- absorption in the mouse cortical collecting duct through an ENaC-dependent mechanism. Click Here
Mar 2013 Journal of Neuroscience Target-Derived Neurotrophins Coordinate Transcription and Transport of Bclw to Prevent Axonal Degeneration Click Here
Mar 2013 JCI NO triggers RGS4 degradation to coordinate angiogenesis and cardiomyocyte growth Click Here
Feb 2013 University of Glasgow Role of Checkpoint Kinase 1 in Malignant Melanoma Click Here
Feb 2013 The Journal of Neuroscience The Angelman Syndrome Protein Ube3a/E6AP Is Required for Golgi Acidification and Surface Protein Sialylation Click Here
Feb 2013 The Journal of Neuroscience Rhes Deletion Is Neuroprotective in the 3-Nitropropionic Acid Model of Huntington's Disease Click Here
Feb 2013 The Journal of Physiology Automated cell-specific laser detection and ablation of neural circuits in neonatal brain tissue Click Here
Feb 2013 JCI Sprouty2, PTEN, and PP2A interact to regulate prostate cancer progression Click Here
Feb 2013 IOVS L450W and Q455K Col8a2 Knock-in Mouse Models of Fuchs Endothelial Corneal Dystrophy Show Distinct Phenotypes and Evidence for Altered Autophagy Click Here
Feb 2013 Journal of Neurophysiology Astrocytic group I mGluR dependent potentiation of astrocytic glutamate and potassium uptake Click Here
Feb 2013 PLOS ONE Deficiency in p38β MAPK Fails to Inhibit Cytokine Production or Protect Neurons against Inflammatory Insult in In Vitro and In Vivo Mouse Models Click Here
Feb 2013 Cell The NeST Long ncRNA Controls Microbial Susceptibility and Epigenetic Activation of the Interferon-γ Locus Click Here
Feb 2013 American Journal of Physiology Mis-expression of the BK K+ channel disrupts suprachiasmatic nucleus circuit rhythmicity and alters clock-controlled behavior Click Here
Feb 2013 Endocrinology Journal Delayed Puberty but Normal Fertility in Mice With Selective Deletion of Insulin Receptors From Kiss1 Cells Click Here
Jan 2013 SciVerse Network of brain protein level changes in glutaminase deficient fetal mice Click Here
Jan 2013 Wiley Online Library The role of the α7 subunit of the nicotinic acetylcholine receptor in the acute toxicosis of methyllycaconitine in mice Click Here
Nov 2012 PLOS ONE Parental Diabetes: The Akita Mouse as a Model of the Effects of Maternal and Paternal Hyperglycemia in Wildtype Offspring Click Here
Nov 2012 SciVerse Bacterial load and inflammation in fetal tissues is not dependent on IL-17a or IL-22 in 10–14 day pregnant mice infected with Listeria monocytogenes Click Here
Oct 2012 The Journal of Neuroscience The Soluble Isoform of CX3CL1 Is Necessary for Neuroprotection in a Mouse Model of Parkinson's Disease Click Here
Oct 2012 Wiley Online Library MMP-3 deletion preserves denervated motor endplates after traumatic nerve injury Click Here
Sept 2012 PLOS ONE Comprehensive Analysis of Ultrasonic Vocalizations in a Mouse Model of Fragile X Syndrome Reveals Limited, Call Type Specific Deficits Click Here
Sept 2012 PLOS ONE A Neonatal Model of Intravenous Staphylococcus epidermidis Infection in Mice <24 h Old Enables Characterization of Early Innate Immune Responses Click Here
Sept 2012 University of Toronto Disruption of Abi1/Hssh3bp1 expression induces prostatic intraepithelial neoplasia in the conditional Abi1/Hssh3bp1KO mice Click Here
Aug 2012 NIH Public Access A Progressive Translational Mouse Model of Human VCP
Disease: The VCP R155H/+ Mouse
Click Here
Aug 2012 PLOS ONE Considerations in the Identification of Endogenous Substrates for Protein L-Isoaspartyl Methyltransferase: The Case of Synuclein Click Here
July 2012 SciVerse Circadian rhythmicity in serotonin transporter knockout mice Click Here
July 2012 Drug Metabolism & Disposition Pharmacokinetics of Oral D-Serine in D-Amino Acid Oxidase Knockout Mice Click Here
July 2012 Nature.com Mutation-independent rescue of a novel mouse model of Retinitis Pigmentosa Click Here
July 2012 IOVS RPGR-associated Retinal Degeneration in Human X-linked RP and a Murine Model Click Here
July 2012 Wiley Online Library A progressive translational mouse model of human VCP disease: The VCP R155H/+ mouse Click Here
July 2012 Cancer Cell The ALKF1174L Mutation Potentiates the Oncogenic Activity of MYCN in Neuroblastoma Click Here
June 2012 Omics Online: Anatomy & Physiology Association of Over-Expressed Estrogen Receptor Alpha with Development of Tamoxifen Resistant Hyperplasia and Adenocarcinomas in Genetically Engineered Mice Click Here
June 2012 SpringerLink A germline-competent embryonic stem cell line from NOD.Cg-PrkdcscidIl2rgtm1Wjl/SzJ (NSG) mice Click Here
June 2012 SciVerse Prediction of death in the SMNΔ7 mouse model of spinal muscular atrophy: Insight into disease stage and progression Click Here
June 2012 Glycobiology Biosynthesis of the major brain gangliosides GD1a adn GT1b Click Here
June 2012 The EULAR Journal A novel mouse model that develops spontaneous arthritis and is predisposed towards atherosclerosis Click Here
May 2012 EMBO Molecular Medicine SPRY2 loss enhances ErbB trafficking and PI3K/AKT signalling to drive human and mouse prostate carcinogenesis Click Here
May 2012 SciVerse Tissue inducible LIfeact expression allows visualization of actin dynamics in vivo and ex vivo Click Here
Apr 2012 Human Molecular Genetics Loss of GM3 synthase gene, but not sphingosine kinase 1, is protective against murine nephronophthisis-related Polycystic Kidney Disease Click Here
Apr 2012 European Journal of Neuroscience 5'Ectonucleotidse-knockout mice lack non-REM sleep responses to sleep deprivation Click Here
Apr 2012 Cancer Prevention Research The CDK4/6 inhibitor  PD0332991 reverses epithelial dysplasia associated with abnormal activation of the Cyclin-CDK-Rb pathway Click Here
Apr 2012 SciVerse E Prostanoid 2 REceptor Signaling Suppresses Lung Innate Immunity against Streptococcus penumoniae Click Here
Apr 2012 SciVerse Hepatitis B virus regulatory HBx protein binding to DDB1 is required but is not sufficient for maximal HBV replication Click Here
Mar 2012 American Journal of Medical Genetics Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure Click Here
Feb 2012 PLOS ONE Neonatal Periostin Knockout Mice Are Protected from Hyperoxia-Induced Alveolar Simplication Click Here
Feb 2012 PLOS ONE The Effects of C75, an Inhibitor of Fatty Acid Synthase, on Sleep and Metabolism in Mice Click Here
Feb 2012 The University of Maryland Serotonergic Modulation of Glutamate Transmission: Bridging Two Theories of Depression Click Here
Feb 2012 PLOS ONE RDH10 Oxidation of Vitamin A Is a Critical Control Step in Synthesis of Retinoic Acid during Mouse Embryogenesis Click Here
Jan 2012 American Diabetes Association Chronic GLP-1 Receptor Activation by Exendin-4 Induces Expansion of Pancreatic Duct Glands in Rats and Accelerates Formation of Dysplastic Lesions and Chronic Pancreatitis in the KrasG12D Mouse Model Click Here
Dec 2011 ScienceDirect Sustained attention in mice: Expanding the translational utility of the SAT by incorporating the Michigan Controlled Access Response Port (MICARP) Click Here
Dec 2011 Nature Autophagic targeting of Src promotes cancer cell survival following reduced FAK signalling Click Here
Dec 2011 The University of British Columbia Determination of disease progression with early toxin-induced neuropathology in the ageing mutant SOD mouse model of amyotrophic lateral sclerosis Click Here
Dec 2011 European Journal of Neuroscience Impaired wake-promoting mechanisms in ghrelin receptor-deficient mice Click Here
Dec 2011 Experimental Oncology Ascorbate depletion increases growth and metastasis of melanoma cells in vitamin c deficient mice Click Here
Dec 2011 Journal of Applied Physiology Brain-specific interleukin-1 receptor accessory protein in sleep regulation Click Here
Dec 2011 Arthritis and Rheumatism Myeloid cell-specific Fas expression is required to prevent systemic autoimmunity Click Here
Nov 2011 European Journal of Immunology CD40 engagement of CD4+CD40+ T Cells in a neoself anitgen disease model ablates CTLA-4 expression and indirectly impacts tolerance Click Here
Nov 2011 JCI Crosstalk between the canonical NF-κB  and Notch signaling and promotes pancreatic cancer progression in mice Click Here
Oct 2011 Human Molecular Genetics CREB-activity and nmnat2 transcription are down-regulated prior to neurodegeneration, while NMNAT2 over-expression is neuroprotective, in a mouse model of human tauopathy Click Here
Oct 2011 APA PsychNET Comprehensive motor testing in Fmr1-KO mice exposes temporal defects in oromotor coordination Click Here
Oct 2011 ScienceDirect Spatial Frequency Threshold and Contrast Sensitivity of an Optomotor Behavior are Impaired in the Ins2 sup Akita sup Mouse Model of Diabetes Click Here
Oct 2011 ScienceDirect Separation of function for classical and ganglion cell photoreceptors with respect to circadian rhythm entrainment and induction of photosomnolence Click Here
Sept 2011 PNAS HER2 overcomes PTEN (loss)-induced senescence to cause aggressive prostate cancer Click Here
Aug 2011 PLOS ONE Mapping Functional Brain Activation Usint [14C]-lodoantipyrine in Male Serotonin Transporter Knockout Mice Click Here
Aug 2011 Journal of Endocrinology Mitogen activated protein kinase phosphatase - 1 regulates bone mass, osteoblast gene expression, and responsiveness to parathyroid hormone Click Here
Aug 2011 Skeletal Muscle Journal Regulation of DMD pathology by an ankyrincoded miRNA Click Here
 July 2011 The Journal of Pharmacology and Experimental Therapeutics Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity Click Here
July 2011  The Journal of Neuroscience  PIP2-Mediated HCN3 Channel Gating Is Crucial for Rhythmic Burst Firing in Thalamic Intergeniculate Leaflet Neurons Click Here
 July 2011  The Journal of Neuroinflammation Microglial p38alpha MAPK is a key regulator of proinflammatory cytokine up-regulation induced by toll-like receptor (TLR) ligands or beta-amyloid (Abeta)  Click Here
June 2011 The Journal of Neuroscience Mature Mice Lacking Rbl2/p130 Gene Have Supernumerary Inner Ear Hair Cells and Supporting Cells Click Here
Apr 2011 The Journal of Neuroscience Circuit-Specific Intracortical Hyperconnectivity in Mice with Deletion of the Autism-Associated Met Receptor Tyrosine Kinase Click Here
Apr 2011 Cancer Cell c-Raf, but Not B-Raf, Is Essential for Development of K-Ras Oncogene-Driven Non-Small Cell Lung Carcinoma Click Here
Mar 2011 Development Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development  Click Here
Feb 2011 The Journal of Sexual Medicine Post-Translational Inactivation of Endothelial Nitric Oxide Synthase in the Transgenic Sickle Cell Mouse Penis Click Here
Feb 2011 PNAS Cystic fibrosis transmembrane conductance regulator with a shortened R domain rescues the intestinal phenotype of CFTR−/− mice Click Here
Feb 2011 The Journal of Physiology Is connexin36 critical for GABAergic hyper-synchronization in the hippocampus? Click Here
Feb 2011 PLOS ONE Neuromuscular Junction Defects in Mice with Mutation of dynein heavy chain 1 Click Here
Feb 2011 Molecular Endocrinology Altered AIB1 or AIB13 Expression Impacts ER Effects on Mammary Gland Stromal and Epithelial Content Click Here
Feb 2011 The Journal of Neuroscience Sensory Neuropathy Attributable to Loss of Bcl-w Click Here
Jan 2011 Nature A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa Click Here
Jan 2011 University of Edinburgh Genome wide gene expression analysis of two ENU mouse models of major mental illness Click Here
Jan 2011 University of Alberta Normal and Pathological Development of the Rodent Primordial Diaphragm Click Here
Jan 2011 BMC Neuroscience Non-invasive quantification of brain tumor-induced astrogliosis Click Here
Jan 2011 The Journal of Neuroscience A Corticosteroid-Responsive Transcription Factor, Promyelocytic Leukemia Zinc Finger Protein, Mediates Protection of the Cochlea from Acoustic Trauma Click Here
Jan 2011 PLOS ONE Blood-Brain Barrier Impairment in and Animal Model of MPS III B Click Here
Jan 2011 ScienceDirect Fatty acid amide hydrolase is a key regulator of endocannabinoid-induced myocardial tissue injury Click Here
Dec 2010 Nature Neuroscience AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training Click Here
Nov 2010 EMBO Molecular Medicine p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium Click Here
Mar 2007 APS

Spontaneous sleep and homeostatic sleep regulation in ghrelin knockout mice

Click Here
Mar 2007 SciVerse
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
Click Here
Apr 2007 ScienceDirect

Mek1/2 MAPK Kinases Are Essential for Mammalian Development, Homeostasis, and Raf-Induced Hyperplasia

Click Here
Aug 2007

The Journal of Neuroscience

Dendritic HCN2 Channels Constrain Glutamate-DrivenExcitability in Reticular Thalamic Neurons

Click Here
Oct 2007 AHA Journal

Fractalkine Deficiency Markedly Reduces Macrophage Accumulation and Atherosclerotic Lesion Formation in CCR2−/− Mice

Click Here
Mar 2008 Behavioural Pharmacology

Effects of SB-269970, a 5-HT7 receptor antagonist, in mouse models predictive of antipsychotic-like activity

Click Here
Sept 2008 SciVerse

Distinct mechanisms of 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyrimidine resistance revealed by transcriptome mapping in mouse striatum

Click Here
Sept 2008 SciVerse

Calcification of multipotent prostate tumor endothelium

Click Here
Oct 2008 SciVerse

Improved insulin sensitivity and metabolic flexibility in ghrelin receptor knockout mice

Click Here
July 2008 British Journal of Cancer

Attenuated p53 activation in tumour-associated stromal cells accompanies decreased sensitivity to etoposide and vincristine

Click Here
July 2008 APS

Involvement of T1R3 in calcium-magnesium taste

Click Here
Jan 2009 books.google.com

Synapsin II and Rab3a are dynamic regulators of vesicle cycling in mouse motor endplates

Click Here
Feb 2009 The Journal of Immunology
Deletion of PPARγ in alveolar macrophages is associated with a Th-1 pulmonary inflammatory response
Click Here
Mar 2009 PNAS

Hv1 proton channels are required for high-level NADPH oxidase-dependent superoxide production during the phagocyte respiratory burst

Click Here
Mar 2009 Nature

Mek1/2 gene dosage determines tissue response to oncogenic Ras signaling in the skinMek1/2 gene dosage dependence of oncogenic Ras

Click Here
Apr 2009 ACS Publications

β1 integrin is an adhesion protein for sperm binding to eggs

Click Here
May 2009 Science AAAS

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

Click Here
May 2009 Nature

Biomechanical forces promote embryonic haematopoiesis

Click Here
June 2009 Epilepsia

Ketogenic diet treatment abolishes seizure periodicity and improves diurnal rhythmicity in epileptic Kcna1‐null mice

Click Here
July 2009 PNAS

A human IL-10 BAC transgene reveals tissue-specific control of IL-10 expression and alters disease outcome

Click Here
July 2009 Journal of Neuroscience

Excitability changes related to GABAA receptor plasticity during pregnancy

Click Here
July 2009 Nature

Contribution of organic cation transporter 2 (OCT2) to cisplatin-induced nephrotoxicity

Click Here
Aug 2009 PNAS

The preproghrelin gene is required for the normal integration of thermoregulation and sleep in mice

Click Here
Aug 2009 SciVerse

PET Imaging of Leptin Biodistribution and Metabolism in Rodents and Primates

Click Here
Sept 2009 SciVerse

Anticonvulsant effects of the selective melatonin receptor agonist ramelteon

Click Here
Oct 2009 JCI

Lack of Protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis

Click Here
Nov 2009 PLOS ONE

CRX is a diagnostic marker of retinal and pineal lineage tumors

Click Here
Dec 2009 NCBI

Increased intake of ethanol and dietary fat in galanin overexpressing mice

Click Here
Jan 2010  The Endocrine Society   Mechanisms of Amylin/Leptin Synergy in Rodent Models  Click Here
 Jan 2010 Alcoholism Clinical & Experimental Research   Galanin Knockout Mice Show Disturbances in Ethanol Consumption and Expression of Hypothalamic Peptides That Stimulate Ethanol Intake  Click Here
 Jan 2010 Science Direct  Nervous-tissue-specific elimination of microtubule-actin crosslinking factor 1a results in multiple developmental defects in the mouse brain   Click Here
 Feb 2010 American Journal of Physiology  Restricted feeding-induced sleep, activity, and body temperature changes in normal and preproghrelin-deficient mice   Click Here
 Feb 2010 American Journal of Physiology  Toll-like receptor 2 mediates mesenchymal stem cell-associated myocardial recovery and VEGF production following acute ischemia-reperfusion injury   Click Here
 Feb 2010 Carcinogenesis  Role of ERα in the differential response of Stat5a loss in susceptibility to mammary preneoplasia and DMBA-induced carcinogenesis   Click Here
Mar 2010 Molecular and Cellular Neuroscience Cooperative regulation of neurotransmitter release by Rab3a and synapsin II Click Here
Mar 2010 Lung Cellular and Molecular Physiology Fibroblast-specific expression of AC6 enhances β-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis Click Here
Apr 2010 The Journal of Immunology Effects of cell-type specific hIL-10 expression on disease susceptibility Click Here
May 2010   UMI Biomechanical control of hematopoiesis  Click Here 
 May 2010 Journal of Neuroscience Methods   Multiple ERβ antisera label in ERβ knockout and null mouse tissues Click Here 
 May 2010 Cancer Research   Deregulated Estrogen Receptor α and p53 Heterozygosity Collaborate in the Development of Mammary Hyperplasia  Click Here
 July 2010 Development   Endothelial α5 and αv integrins cooperate in remodeling of the vasculature during development Click Here 
July 2010  Science Direct   Measures of bulbar and spinal motor function, muscle innervation, and mitochondrial function in ALS rats Click Here 
July 2010 KU Scholar Works

Requirement for fibroblast growth factor receptor 1 in hematopoietic stem cells under stress but not during homeostasis

Click Here
Aug 2010   Journal of Applied Physiology ATP and the purine type 2 X7 receptor affect sleep   Click Here
Aug 2010 University of Eastern Michigan

Receptor-dependent phagocytosis of clostridium sordellii by human decidual macrophages

Click Here
Sept 2010  The Journal of Neuroscience  Pyramidal Neurons Are Generated from Oligodendroglial Progenitor Cells in Adult Piriform Cortex Click Here 
Sept 2010 The Journal of Immunology The Class A Scavenger Receptor, Macrophage Receptor with Collagenous Structure, Is the Major Phagocytic Receptor for Clostridium sordellii Expressed by Human Decidual Macrophages Click Here
Jan 2007 PNAS Increased apoptosis, p53 up-regulation, and cerebellar neuronal degeneration in repair-deficient Cockayne syndrome mice Click Here
Aug 2006 Science AAAS Human Validated Kinase siRNA Set Click Here
 
 

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